LeishMANIAdb
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H1 histone-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
H1 histone-like protein
Gene product:
h1 histone-like protein
Species:
Leishmania braziliensis
UniProt:
A4HM32_LEIBR
TriTrypDb:
LbrM.33.3520 , LBRM2903_330043900
Length:
137

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HM32
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HM32

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 10 12 PF00675 0.646
CLV_NRD_NRD_1 132 134 PF00675 0.678
CLV_NRD_NRD_1 135 137 PF00675 0.736
CLV_PCSK_KEX2_1 128 130 PF00082 0.543
CLV_PCSK_PC1ET2_1 128 130 PF00082 0.543
CLV_PCSK_SKI1_1 128 132 PF00082 0.668
CLV_PCSK_SKI1_1 84 88 PF00082 0.652
DEG_APCC_DBOX_1 2 10 PF00400 0.528
DEG_Nend_Nbox_1 1 3 PF02207 0.637
DOC_USP7_MATH_1 23 27 PF00917 0.585
DOC_USP7_MATH_1 56 60 PF00917 0.467
DOC_USP7_MATH_1 92 96 PF00917 0.628
DOC_USP7_UBL2_3 12 16 PF12436 0.643
DOC_USP7_UBL2_3 120 124 PF12436 0.597
DOC_USP7_UBL2_3 87 91 PF12436 0.697
DOC_WW_Pin1_4 115 120 PF00397 0.503
LIG_14-3-3_CanoR_1 3 7 PF00244 0.628
LIG_14-3-3_CanoR_1 55 65 PF00244 0.685
LIG_FHA_1 102 108 PF00498 0.525
LIG_FHA_1 116 122 PF00498 0.560
LIG_SH3_3 40 46 PF00018 0.607
LIG_SH3_3 66 72 PF00018 0.496
LIG_SH3_3 77 83 PF00018 0.474
MOD_CDK_SPK_2 115 120 PF00069 0.503
MOD_CK1_1 26 32 PF00069 0.669
MOD_CK1_1 95 101 PF00069 0.744
MOD_Cter_Amidation 73 76 PF01082 0.681
MOD_GSK3_1 91 98 PF00069 0.574
MOD_NEK2_1 2 7 PF00069 0.630
MOD_NEK2_2 50 55 PF00069 0.593
MOD_PIKK_1 56 62 PF00454 0.677
MOD_PKA_2 2 8 PF00069 0.631
MOD_PKA_2 92 98 PF00069 0.761
MOD_Plk_1 101 107 PF00069 0.523
MOD_ProDKin_1 115 121 PF00069 0.502
TRG_NLS_Bipartite_1 96 118 PF00514 0.521
TRG_NLS_MonoExtC_3 132 137 PF00514 0.523
TRG_NLS_MonoExtN_4 131 137 PF00514 0.549

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5K8 Leptomonas seymouri 40% 91%
A0A3Q8IH60 Leishmania donovani 60% 100%
A4I9G5 Leishmania infantum 60% 100%
E9B4G3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 60% 96%
Q4Q3L2 Leishmania major 57% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS