Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HM00_LEIBR

TriTrypDb:

LbrM.33.3180 , LBRM2903_330039700

Length:

262

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 1, no: 1
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A4HM00

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HM00

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	163	167	PF00656	0.701
CLV_C14_Caspase3-7	256	260	PF00656	0.661
CLV_NRD_NRD_1	231	233	PF00675	0.477
CLV_NRD_NRD_1	237	239	PF00675	0.455
CLV_PCSK_FUR_1	234	238	PF00082	0.466
CLV_PCSK_FUR_1	88	92	PF00082	0.516
CLV_PCSK_KEX2_1	231	233	PF00082	0.512
CLV_PCSK_KEX2_1	236	238	PF00082	0.499
CLV_PCSK_KEX2_1	51	53	PF00082	0.614
CLV_PCSK_KEX2_1	85	87	PF00082	0.513
CLV_PCSK_KEX2_1	90	92	PF00082	0.452
CLV_PCSK_PC1ET2_1	51	53	PF00082	0.631
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.388
CLV_PCSK_PC1ET2_1	90	92	PF00082	0.392
CLV_PCSK_PC7_1	232	238	PF00082	0.469
CLV_PCSK_PC7_1	86	92	PF00082	0.499
CLV_PCSK_SKI1_1	128	132	PF00082	0.503
CLV_PCSK_SKI1_1	37	41	PF00082	0.661
DEG_APCC_DBOX_1	237	245	PF00400	0.696
DEG_APCC_DBOX_1	40	48	PF00400	0.472
DEG_MDM2_SWIB_1	75	82	PF02201	0.600
DEG_SPOP_SBC_1	15	19	PF00917	0.739
DOC_CYCLIN_yCln2_LP_2	131	137	PF00134	0.686
DOC_MAPK_RevD_3	71	86	PF00069	0.586
DOC_USP7_MATH_1	145	149	PF00917	0.734
DOC_USP7_MATH_1	15	19	PF00917	0.698
DOC_USP7_MATH_1	164	168	PF00917	0.605
DOC_USP7_MATH_1	226	230	PF00917	0.832
DOC_WW_Pin1_4	141	146	PF00397	0.768
LIG_14-3-3_CanoR_1	140	146	PF00244	0.702
LIG_14-3-3_CanoR_1	242	250	PF00244	0.729
LIG_14-3-3_CanoR_1	35	40	PF00244	0.482
LIG_BIR_II_1	1	5	PF00653	0.522
LIG_EH_1	132	136	PF12763	0.687
LIG_FHA_1	56	62	PF00498	0.425
LIG_FHA_2	122	128	PF00498	0.791
LIG_LIR_Gen_1	68	78	PF02991	0.339
LIG_LIR_Nem_3	68	73	PF02991	0.355
LIG_Pex14_2	75	79	PF04695	0.515
LIG_SH2_SRC	103	106	PF00017	0.638
LIG_SH2_STAT5	103	106	PF00017	0.660
LIG_SH3_3	187	193	PF00018	0.721
LIG_SH3_3	201	207	PF00018	0.745
LIG_SH3_3	21	27	PF00018	0.609
LIG_SUMO_SIM_par_1	251	259	PF11976	0.669
LIG_TRAF2_1	107	110	PF00917	0.750
LIG_TRAF2_1	218	221	PF00917	0.816
MOD_CK1_1	13	19	PF00069	0.545
MOD_CK1_1	136	142	PF00069	0.802
MOD_CK2_1	104	110	PF00069	0.638
MOD_CK2_1	121	127	PF00069	0.717
MOD_CK2_1	169	175	PF00069	0.685
MOD_GlcNHglycan	116	119	PF01048	0.491
MOD_GlcNHglycan	135	138	PF01048	0.491
MOD_GlcNHglycan	141	144	PF01048	0.511
MOD_GlcNHglycan	162	165	PF01048	0.607
MOD_GlcNHglycan	166	170	PF01048	0.561
MOD_GlcNHglycan	244	247	PF01048	0.496
MOD_GlcNHglycan	67	70	PF01048	0.494
MOD_GSK3_1	10	17	PF00069	0.508
MOD_GSK3_1	110	117	PF00069	0.723
MOD_GSK3_1	141	148	PF00069	0.725
MOD_GSK3_1	160	167	PF00069	0.618
MOD_LATS_1	240	246	PF00433	0.698
MOD_N-GLC_1	35	40	PF02516	0.677
MOD_NEK2_1	1	6	PF00069	0.503
MOD_PKA_2	139	145	PF00069	0.687
MOD_PKA_2	169	175	PF00069	0.709
MOD_PKB_1	35	43	PF00069	0.456
MOD_Plk_1	35	41	PF00069	0.466
MOD_Plk_4	1	7	PF00069	0.503
MOD_Plk_4	121	127	PF00069	0.755
MOD_Plk_4	169	175	PF00069	0.690
MOD_ProDKin_1	141	147	PF00069	0.769
TRG_ER_diArg_1	231	234	PF00400	0.715
TRG_ER_diArg_1	235	238	PF00400	0.716
TRG_ER_diArg_1	34	37	PF00400	0.485
TRG_ER_diArg_1	91	94	PF00400	0.618

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X746	Leishmania donovani	44%	100%