LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Flagellum attachment zone protein 12
Species:
Leishmania braziliensis
UniProt:
A4HLV7_LEIBR
TriTrypDb:
LbrM.33.2730 , LBRM2903_330035100 *
Length:
1044

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HLV7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HLV7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 180 184 PF00656 0.516
CLV_C14_Caspase3-7 196 200 PF00656 0.465
CLV_C14_Caspase3-7 278 282 PF00656 0.485
CLV_C14_Caspase3-7 654 658 PF00656 0.586
CLV_C14_Caspase3-7 676 680 PF00656 0.558
CLV_C14_Caspase3-7 700 704 PF00656 0.543
CLV_C14_Caspase3-7 765 769 PF00656 0.379
CLV_NRD_NRD_1 1021 1023 PF00675 0.522
CLV_NRD_NRD_1 211 213 PF00675 0.541
CLV_NRD_NRD_1 607 609 PF00675 0.514
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I9F7 Leptomonas seymouri 54% 100%
A0A3S5H7V1 Leishmania donovani 71% 99%
D0A666 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 97%
E9AHR4 Leishmania infantum 71% 99%
E9B485 Leishmania mexicana (strain MHOM/GT/2001/U1103) 70% 99%
Q4Q3U1 Leishmania major 71% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS