Chromosome segregation ATPase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HLU0_LEIBR

TriTrypDb:

LbrM.33.2560 , LBRM2903_330033200

Length:

894

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HLU0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HLU0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	23	27	PF00656	0.622
CLV_NRD_NRD_1	770	772	PF00675	0.459
CLV_NRD_NRD_1	849	851	PF00675	0.499
CLV_NRD_NRD_1	859	861	PF00675	0.522
CLV_PCSK_FUR_1	810	814	PF00082	0.452
CLV_PCSK_KEX2_1	770	772	PF00082	0.459
CLV_PCSK_KEX2_1	792	794	PF00082	0.537
CLV_PCSK_KEX2_1	812	814	PF00082	0.411
CLV_PCSK_KEX2_1	858	860	PF00082	0.548
CLV_PCSK_PC1ET2_1	792	794	PF00082	0.537
CLV_PCSK_PC1ET2_1	812	814	PF00082	0.411
CLV_PCSK_SKI1_1	813	817	PF00082	0.484
CLV_Separin_Metazoa	98	102	PF03568	0.475
DEG_Nend_UBRbox_3	1	3	PF02207	0.608
DEG_SPOP_SBC_1	155	159	PF00917	0.497
DEG_SPOP_SBC_1	194	198	PF00917	0.491
DEG_SPOP_SBC_1	247	251	PF00917	0.508
DEG_SPOP_SBC_1	286	290	PF00917	0.590
DEG_SPOP_SBC_1	325	329	PF00917	0.547
DEG_SPOP_SBC_1	364	368	PF00917	0.554
DEG_SPOP_SBC_1	403	407	PF00917	0.544
DEG_SPOP_SBC_1	442	446	PF00917	0.496
DEG_SPOP_SBC_1	45	49	PF00917	0.677
DEG_SPOP_SBC_1	481	485	PF00917	0.512
DEG_SPOP_SBC_1	534	538	PF00917	0.518
DEG_SPOP_SBC_1	573	577	PF00917	0.508
DEG_SPOP_SBC_1	612	616	PF00917	0.607
DEG_SPOP_SBC_1	651	655	PF00917	0.560
DEG_SPOP_SBC_1	690	694	PF00917	0.539
DEG_SPOP_SBC_1	729	733	PF00917	0.529
DOC_MAPK_gen_1	770	778	PF00069	0.469
DOC_PP4_FxxP_1	777	780	PF00568	0.503
DOC_USP7_MATH_1	115	119	PF00917	0.728
DOC_USP7_MATH_1	155	159	PF00917	0.715
DOC_USP7_MATH_1	194	198	PF00917	0.565
DOC_USP7_MATH_1	247	251	PF00917	0.726
DOC_USP7_MATH_1	28	32	PF00917	0.631
DOC_USP7_MATH_1	286	290	PF00917	0.714
DOC_USP7_MATH_1	325	329	PF00917	0.569
DOC_USP7_MATH_1	364	368	PF00917	0.575
DOC_USP7_MATH_1	403	407	PF00917	0.566
DOC_USP7_MATH_1	442	446	PF00917	0.517
DOC_USP7_MATH_1	481	485	PF00917	0.535
DOC_USP7_MATH_1	534	538	PF00917	0.540
DOC_USP7_MATH_1	573	577	PF00917	0.529
DOC_USP7_MATH_1	612	616	PF00917	0.629
DOC_USP7_MATH_1	651	655	PF00917	0.583
DOC_USP7_MATH_1	690	694	PF00917	0.562
DOC_USP7_MATH_1	729	733	PF00917	0.552
DOC_USP7_UBL2_3	812	816	PF12436	0.451
DOC_WW_Pin1_4	113	118	PF00397	0.764
DOC_WW_Pin1_4	8	13	PF00397	0.630
LIG_14-3-3_CanoR_1	39	46	PF00244	0.631
LIG_FHA_1	161	167	PF00498	0.461
LIG_FHA_1	200	206	PF00498	0.458
LIG_FHA_1	253	259	PF00498	0.547
LIG_FHA_1	292	298	PF00498	0.505
LIG_FHA_1	331	337	PF00498	0.516
LIG_FHA_1	370	376	PF00498	0.539
LIG_FHA_1	409	415	PF00498	0.510
LIG_FHA_1	448	454	PF00498	0.496
LIG_FHA_1	481	487	PF00498	0.474
LIG_FHA_1	495	501	PF00498	0.438
LIG_FHA_1	540	546	PF00498	0.490
LIG_FHA_1	579	585	PF00498	0.532
LIG_FHA_1	618	624	PF00498	0.560
LIG_FHA_1	657	663	PF00498	0.529
LIG_FHA_1	696	702	PF00498	0.507
LIG_FHA_1	735	741	PF00498	0.499
LIG_FHA_2	4	10	PF00498	0.568
LIG_FHA_2	51	57	PF00498	0.605
LIG_LIR_Apic_2	774	780	PF02991	0.488
LIG_LIR_Gen_1	56	65	PF02991	0.760
LIG_LIR_Gen_1	66	75	PF02991	0.596
LIG_LIR_Nem_3	56	61	PF02991	0.775
LIG_LIR_Nem_3	66	72	PF02991	0.598
LIG_LIR_Nem_3	886	890	PF02991	0.516
LIG_Pex14_2	777	781	PF04695	0.506
LIG_RPA_C_Fungi	123	135	PF08784	0.479
LIG_RPA_C_Fungi	137	149	PF08784	0.422
LIG_RPA_C_Fungi	176	188	PF08784	0.477
LIG_RPA_C_Fungi	215	227	PF08784	0.479
LIG_RPA_C_Fungi	229	241	PF08784	0.430
LIG_RPA_C_Fungi	268	280	PF08784	0.468
LIG_RPA_C_Fungi	307	319	PF08784	0.520
LIG_RPA_C_Fungi	346	358	PF08784	0.560
LIG_RPA_C_Fungi	385	397	PF08784	0.527
LIG_RPA_C_Fungi	424	436	PF08784	0.484
LIG_RPA_C_Fungi	463	475	PF08784	0.511
LIG_RPA_C_Fungi	502	514	PF08784	0.462
LIG_RPA_C_Fungi	516	528	PF08784	0.432
LIG_RPA_C_Fungi	555	567	PF08784	0.517
LIG_RPA_C_Fungi	594	606	PF08784	0.552
LIG_RPA_C_Fungi	633	645	PF08784	0.554
LIG_RPA_C_Fungi	672	684	PF08784	0.527
LIG_RPA_C_Fungi	711	723	PF08784	0.515
LIG_RPA_C_Fungi	750	762	PF08784	0.506
LIG_SH2_CRK	58	62	PF00017	0.766
LIG_SH2_GRB2like	58	61	PF00017	0.571
LIG_SH2_GRB2like	69	72	PF00017	0.476
LIG_SH2_SRC	69	72	PF00017	0.471
LIG_SH2_STAT5	33	36	PF00017	0.655
LIG_SH3_3	111	117	PF00018	0.632
LIG_SUMO_SIM_anti_2	96	101	PF11976	0.492
LIG_TRAF2_1	853	856	PF00917	0.476
LIG_TYR_ITAM	66	82	PF00017	0.471
LIG_TYR_ITIM	67	72	PF00017	0.473
LIG_UBA3_1	99	103	PF00899	0.480
LIG_WRC_WIRS_1	4	9	PF05994	0.568
MOD_CDK_SPxxK_3	113	120	PF00069	0.760
MOD_CK1_1	29	35	PF00069	0.666
MOD_CK1_1	295	301	PF00069	0.660
MOD_CK1_1	373	379	PF00069	0.525
MOD_CK1_1	38	44	PF00069	0.805
MOD_CK1_1	412	418	PF00069	0.501
MOD_CK1_1	47	53	PF00069	0.751
MOD_CK2_1	115	121	PF00069	0.556
MOD_CK2_1	155	161	PF00069	0.519
MOD_CK2_1	194	200	PF00069	0.637
MOD_CK2_1	247	253	PF00069	0.534
MOD_CK2_1	286	292	PF00069	0.517
MOD_CK2_1	325	331	PF00069	0.564
MOD_CK2_1	364	370	PF00069	0.573
MOD_CK2_1	403	409	PF00069	0.566
MOD_CK2_1	442	448	PF00069	0.515
MOD_CK2_1	481	487	PF00069	0.535
MOD_CK2_1	50	56	PF00069	0.616
MOD_CK2_1	534	540	PF00069	0.542
MOD_CK2_1	573	579	PF00069	0.532
MOD_CK2_1	612	618	PF00069	0.627
MOD_CK2_1	651	657	PF00069	0.583
MOD_CK2_1	690	696	PF00069	0.563
MOD_CK2_1	729	735	PF00069	0.553
MOD_CMANNOS	884	887	PF00535	0.524
MOD_GlcNHglycan	117	120	PF01048	0.675
MOD_GlcNHglycan	158	161	PF01048	0.514
MOD_GlcNHglycan	197	200	PF01048	0.587
MOD_GlcNHglycan	250	253	PF01048	0.700
MOD_GlcNHglycan	26	29	PF01048	0.625
MOD_GlcNHglycan	289	292	PF01048	0.725
MOD_GlcNHglycan	297	300	PF01048	0.609
MOD_GlcNHglycan	328	331	PF01048	0.581
MOD_GlcNHglycan	367	370	PF01048	0.773
MOD_GlcNHglycan	375	378	PF01048	0.541
MOD_GlcNHglycan	406	409	PF01048	0.525
MOD_GlcNHglycan	414	417	PF01048	0.491
MOD_GlcNHglycan	445	448	PF01048	0.513
MOD_GlcNHglycan	537	540	PF01048	0.503
MOD_GlcNHglycan	576	579	PF01048	0.535
MOD_GlcNHglycan	615	618	PF01048	0.581
MOD_GlcNHglycan	654	657	PF01048	0.539
MOD_GlcNHglycan	693	696	PF01048	0.520
MOD_GlcNHglycan	732	735	PF01048	0.511
MOD_GlcNHglycan	865	869	PF01048	0.571
MOD_GSK3_1	156	163	PF00069	0.500
MOD_GSK3_1	195	202	PF00069	0.620
MOD_GSK3_1	20	27	PF00069	0.662
MOD_GSK3_1	248	255	PF00069	0.532
MOD_GSK3_1	28	35	PF00069	0.635
MOD_GSK3_1	287	294	PF00069	0.706
MOD_GSK3_1	326	333	PF00069	0.561
MOD_GSK3_1	365	372	PF00069	0.550
MOD_GSK3_1	40	47	PF00069	0.629
MOD_GSK3_1	404	411	PF00069	0.509
MOD_GSK3_1	443	450	PF00069	0.536
MOD_GSK3_1	482	489	PF00069	0.516
MOD_GSK3_1	535	542	PF00069	0.524
MOD_GSK3_1	574	581	PF00069	0.520
MOD_GSK3_1	613	620	PF00069	0.605
MOD_GSK3_1	652	659	PF00069	0.565
MOD_GSK3_1	691	698	PF00069	0.545
MOD_GSK3_1	730	737	PF00069	0.535
MOD_GSK3_1	872	879	PF00069	0.591
MOD_LATS_1	37	43	PF00433	0.630
MOD_N-GLC_1	35	40	PF02516	0.738
MOD_NEK2_1	124	129	PF00069	0.602
MOD_NEK2_1	82	87	PF00069	0.547
MOD_NEK2_1	827	832	PF00069	0.421
MOD_NEK2_2	3	8	PF00069	0.569
MOD_PIKK_1	26	32	PF00454	0.667
MOD_PIKK_1	827	833	PF00454	0.424
MOD_PKA_2	161	167	PF00069	0.472
MOD_PKA_2	200	206	PF00069	0.458
MOD_PKA_2	253	259	PF00069	0.539
MOD_PKA_2	292	298	PF00069	0.574
MOD_PKA_2	331	337	PF00069	0.516
MOD_PKA_2	370	376	PF00069	0.539
MOD_PKA_2	38	44	PF00069	0.628
MOD_PKA_2	409	415	PF00069	0.510
MOD_PKA_2	448	454	PF00069	0.496
MOD_PKA_2	540	546	PF00069	0.490
MOD_PKA_2	579	585	PF00069	0.532
MOD_PKA_2	618	624	PF00069	0.560
MOD_PKA_2	657	663	PF00069	0.529
MOD_PKA_2	696	702	PF00069	0.507
MOD_PKA_2	735	741	PF00069	0.499
MOD_PKA_2	83	89	PF00069	0.550
MOD_Plk_1	827	833	PF00069	0.424
MOD_Plk_1	872	878	PF00069	0.546
MOD_Plk_4	41	47	PF00069	0.639
MOD_ProDKin_1	113	119	PF00069	0.762
MOD_ProDKin_1	8	14	PF00069	0.632
MOD_SUMO_rev_2	785	794	PF00179	0.540
TRG_DiLeu_BaEn_1	865	870	PF01217	0.586
TRG_DiLeu_BaLyEn_6	821	826	PF01217	0.436
TRG_ENDOCYTIC_2	58	61	PF00928	0.777
TRG_ENDOCYTIC_2	69	72	PF00928	0.569
TRG_ENDOCYTIC_2	79	82	PF00928	0.511
TRG_ER_diArg_1	769	771	PF00400	0.457
TRG_ER_diArg_1	857	860	PF00400	0.547
TRG_ER_diArg_1	877	880	PF00400	0.495
TRG_Pf-PMV_PEXEL_1	120	125	PF00026	0.583
TRG_Pf-PMV_PEXEL_1	73	77	PF00026	0.642
TRG_Pf-PMV_PEXEL_1	805	809	PF00026	0.447
TRG_Pf-PMV_PEXEL_1	824	828	PF00026	0.390

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X6W4	Leishmania donovani	62%	85%
E9B466	Leishmania mexicana (strain MHOM/GT/2001/U1103)	62%	100%