Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HLR4_LEIBR

TriTrypDb:

LbrM.33.2300 , LBRM2903_330030100

Length:

849

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

A4HLR4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HLR4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	327	331	PF00656	0.656
CLV_NRD_NRD_1	328	330	PF00675	0.459
CLV_NRD_NRD_1	380	382	PF00675	0.612
CLV_NRD_NRD_1	384	386	PF00675	0.588
CLV_NRD_NRD_1	568	570	PF00675	0.865
CLV_NRD_NRD_1	625	627	PF00675	0.528
CLV_PCSK_FUR_1	326	330	PF00082	0.459
CLV_PCSK_FUR_1	685	689	PF00082	0.401
CLV_PCSK_KEX2_1	328	330	PF00082	0.456
CLV_PCSK_KEX2_1	342	344	PF00082	0.480

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7U8	Leishmania donovani	50%	100%
A4I964	Leishmania infantum	51%	100%
E9B440	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	98%
Q4Q3Y5	Leishmania major	51%	100%

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