Putative phosphoribosylpyrophosphate synthetase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphoribosylpyrophosphate synthetase, putative

Species:

Leishmania braziliensis

UniProt:

A4HLQ5_LEIBR

TriTrypDb:

LbrM.33.2210 , LBRM2903_330029000

Length:

356

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 75

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 33
NetGPI	no	yes: 0, no: 33

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	4
GO:0002189	ribose phosphate diphosphokinase complex	5	3
GO:0005737	cytoplasm	2	3
GO:0032991	protein-containing complex	1	3
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	3
GO:1902494	catalytic complex	2	3
GO:1990234	transferase complex	3	3

Expansion

Sequence features

A4HLQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HLQ5

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	34
GO:0006725	cellular aromatic compound metabolic process	3	34
GO:0006753	nucleoside phosphate metabolic process	4	34
GO:0006793	phosphorus metabolic process	3	34
GO:0006796	phosphate-containing compound metabolic process	4	34
GO:0006807	nitrogen compound metabolic process	2	34
GO:0008152	metabolic process	1	34
GO:0009058	biosynthetic process	2	34
GO:0009117	nucleotide metabolic process	5	34
GO:0009165	nucleotide biosynthetic process	6	34
GO:0009987	cellular process	1	34
GO:0018130	heterocycle biosynthetic process	4	34
GO:0019438	aromatic compound biosynthetic process	4	34
GO:0019637	organophosphate metabolic process	3	34
GO:0034641	cellular nitrogen compound metabolic process	3	34
GO:0034654	nucleobase-containing compound biosynthetic process	4	34
GO:0044237	cellular metabolic process	2	34
GO:0044238	primary metabolic process	2	34
GO:0044249	cellular biosynthetic process	3	34
GO:0044271	cellular nitrogen compound biosynthetic process	4	34
GO:0044281	small molecule metabolic process	2	34
GO:0046483	heterocycle metabolic process	3	34
GO:0055086	nucleobase-containing small molecule metabolic process	3	34
GO:0071704	organic substance metabolic process	2	34
GO:0090407	organophosphate biosynthetic process	4	34
GO:1901293	nucleoside phosphate biosynthetic process	5	34
GO:1901360	organic cyclic compound metabolic process	3	34
GO:1901362	organic cyclic compound biosynthetic process	4	34
GO:1901576	organic substance biosynthetic process	3	34
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	6	3
GO:0006163	purine nucleotide metabolic process	5	3
GO:0006164	purine nucleotide biosynthetic process	6	3
GO:0019693	ribose phosphate metabolic process	4	3
GO:0046390	ribose phosphate biosynthetic process	5	3
GO:0046391	5-phosphoribose 1-diphosphate metabolic process	5	3
GO:0072521	purine-containing compound metabolic process	4	3
GO:0072522	purine-containing compound biosynthetic process	5	3
GO:1901135	carbohydrate derivative metabolic process	3	3
GO:1901137	carbohydrate derivative biosynthetic process	4	3
GO:1901564	organonitrogen compound metabolic process	3	3
GO:1901566	organonitrogen compound biosynthetic process	4	3
GO:0016310	phosphorylation	5	3

Molecular functions
Term	Name	Level	Count
GO:0000287	magnesium ion binding	5	34
GO:0003824	catalytic activity	1	34
GO:0004749	ribose phosphate diphosphokinase activity	5	34
GO:0005488	binding	1	34
GO:0016740	transferase activity	2	34
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	34
GO:0016778	diphosphotransferase activity	4	34
GO:0043167	ion binding	2	34
GO:0043169	cation binding	3	34
GO:0046872	metal ion binding	4	34
GO:0016301	kinase activity	4	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	46	50	PF00656	0.589
CLV_NRD_NRD_1	134	136	PF00675	0.295
CLV_NRD_NRD_1	234	236	PF00675	0.516
CLV_PCSK_KEX2_1	119	121	PF00082	0.259
CLV_PCSK_KEX2_1	233	235	PF00082	0.467
CLV_PCSK_KEX2_1	65	67	PF00082	0.305
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.269
CLV_PCSK_PC1ET2_1	233	235	PF00082	0.471
CLV_PCSK_PC1ET2_1	65	67	PF00082	0.305
CLV_PCSK_PC7_1	61	67	PF00082	0.323
CLV_PCSK_SKI1_1	119	123	PF00082	0.290
CLV_PCSK_SKI1_1	159	163	PF00082	0.342
DOC_CDC14_PxL_1	330	338	PF14671	0.464
DOC_MAPK_gen_1	135	143	PF00069	0.478
DOC_MAPK_gen_1	320	329	PF00069	0.485
DOC_MAPK_MEF2A_6	135	143	PF00069	0.470
DOC_USP7_MATH_1	285	289	PF00917	0.491
DOC_USP7_MATH_1	339	343	PF00917	0.577
DOC_WW_Pin1_4	2	7	PF00397	0.671
DOC_WW_Pin1_4	204	209	PF00397	0.447
LIG_14-3-3_CanoR_1	120	128	PF00244	0.445
LIG_14-3-3_CanoR_1	135	139	PF00244	0.496
LIG_14-3-3_CanoR_1	140	148	PF00244	0.482
LIG_14-3-3_CanoR_1	159	164	PF00244	0.355
LIG_14-3-3_CanoR_1	222	232	PF00244	0.368
LIG_14-3-3_CanoR_1	318	327	PF00244	0.606
LIG_Actin_WH2_2	99	116	PF00022	0.485
LIG_APCC_ABBA_1	182	187	PF00400	0.355
LIG_BIR_II_1	1	5	PF00653	0.730
LIG_BIR_III_4	209	213	PF00653	0.459
LIG_BRCT_BRCA1_1	349	353	PF00533	0.480
LIG_BRCT_BRCA1_2	349	355	PF00533	0.491
LIG_FHA_1	110	116	PF00498	0.472
LIG_FHA_1	120	126	PF00498	0.445
LIG_FHA_1	160	166	PF00498	0.321
LIG_FHA_1	201	207	PF00498	0.355
LIG_FHA_1	252	258	PF00498	0.501
LIG_FHA_1	279	285	PF00498	0.494
LIG_FHA_1	330	336	PF00498	0.577
LIG_FHA_1	46	52	PF00498	0.580
LIG_Integrin_RGD_1	81	83	PF01839	0.275
LIG_LIR_Gen_1	350	356	PF02991	0.538
LIG_LIR_LC3C_4	307	311	PF02991	0.508
LIG_LIR_Nem_3	187	191	PF02991	0.368
LIG_LIR_Nem_3	350	356	PF02991	0.521
LIG_PCNA_yPIPBox_3	100	114	PF02747	0.480
LIG_PCNA_yPIPBox_3	175	183	PF02747	0.427
LIG_PDZ_Class_2	351	356	PF00595	0.686
LIG_REV1ctd_RIR_1	171	177	PF16727	0.396
LIG_REV1ctd_RIR_1	18	27	PF16727	0.584
LIG_SH2_CRK	253	257	PF00017	0.505
LIG_SH2_SRC	128	131	PF00017	0.546
LIG_SH2_STAP1	253	257	PF00017	0.505
LIG_SH2_STAT3	130	133	PF00017	0.483
LIG_SH2_STAT5	191	194	PF00017	0.413
LIG_SH2_STAT5	253	256	PF00017	0.491
LIG_SH3_1	136	142	PF00018	0.480
LIG_SH3_3	136	142	PF00018	0.489
LIG_SH3_3	202	208	PF00018	0.437
LIG_SUMO_SIM_anti_2	105	112	PF11976	0.483
LIG_SUMO_SIM_anti_2	325	332	PF11976	0.538
LIG_SUMO_SIM_par_1	105	112	PF11976	0.480
LIG_SUMO_SIM_par_1	202	207	PF11976	0.398
LIG_TRAF2_1	305	308	PF00917	0.536
LIG_UBA3_1	106	114	PF00899	0.482
MOD_CK1_1	2	8	PF00069	0.747
MOD_CK1_1	243	249	PF00069	0.480
MOD_CK1_1	348	354	PF00069	0.501
MOD_GlcNHglycan	1	4	PF01048	0.772
MOD_GlcNHglycan	116	119	PF01048	0.279
MOD_GlcNHglycan	143	146	PF01048	0.296
MOD_GlcNHglycan	39	42	PF01048	0.291
MOD_GSK3_1	109	116	PF00069	0.497
MOD_GSK3_1	200	207	PF00069	0.372
MOD_GSK3_1	223	230	PF00069	0.386
MOD_GSK3_1	325	332	PF00069	0.534
MOD_GSK3_1	94	101	PF00069	0.492
MOD_N-GLC_1	200	205	PF02516	0.510
MOD_N-GLC_2	301	303	PF02516	0.285
MOD_NEK2_1	109	114	PF00069	0.483
MOD_NEK2_1	261	266	PF00069	0.493
MOD_NEK2_1	278	283	PF00069	0.508
MOD_NEK2_2	16	21	PF00069	0.547
MOD_NEK2_2	339	344	PF00069	0.558
MOD_PKA_1	119	125	PF00069	0.455
MOD_PKA_2	119	125	PF00069	0.474
MOD_PKA_2	134	140	PF00069	0.497
MOD_PKB_1	35	43	PF00069	0.323
MOD_Plk_1	200	206	PF00069	0.397
MOD_Plk_1	345	351	PF00069	0.489
MOD_Plk_4	16	22	PF00069	0.576
MOD_Plk_4	187	193	PF00069	0.403
MOD_Plk_4	200	206	PF00069	0.397
MOD_Plk_4	227	233	PF00069	0.382
MOD_Plk_4	325	331	PF00069	0.497
MOD_Plk_4	348	354	PF00069	0.504
MOD_ProDKin_1	2	8	PF00069	0.668
MOD_ProDKin_1	204	210	PF00069	0.458
MOD_SUMO_rev_2	131	137	PF00179	0.470
MOD_SUMO_rev_2	58	67	PF00179	0.500
TRG_DiLeu_BaEn_1	105	110	PF01217	0.480
TRG_DiLeu_BaLyEn_6	331	336	PF01217	0.475
TRG_DiLeu_BaLyEn_6	34	39	PF01217	0.439
TRG_ENDOCYTIC_2	253	256	PF00928	0.491
TRG_ER_diArg_1	34	37	PF00400	0.419
TRG_NES_CRM1_1	46	58	PF08389	0.546

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8G4	Leptomonas seymouri	92%	99%
A0A0N1I914	Leptomonas seymouri	56%	99%
A0A0N1PE41	Leptomonas seymouri	55%	97%
A0A0S4IME5	Bodo saltans	75%	100%
A0A0S4IQW2	Bodo saltans	51%	78%
A0A0S4IW81	Bodo saltans	56%	96%
A0A1X0NFA8	Trypanosomatidae	53%	91%
A0A1X0P0G5	Trypanosomatidae	54%	91%
A0A1X0P3L9	Trypanosomatidae	82%	100%
A0A3Q8IHV7	Leishmania donovani	54%	99%
A0A3R7KT84	Trypanosoma rangeli	80%	98%
A0A422NFU4	Trypanosoma rangeli	48%	84%
A0A422NKU6	Trypanosoma rangeli	55%	91%
A2VDS0	Bos taurus	30%	96%
A4H5F1	Leishmania braziliensis	56%	100%
A4HQ54	Leishmania braziliensis	55%	99%
A4HTP6	Leishmania infantum	56%	96%
A4I955	Leishmania infantum	97%	100%
A4IDV3	Leishmania infantum	55%	99%
A5UNK4	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	34%	100%
A6W1C7	Marinomonas sp. (strain MWYL1)	39%	100%
B0R7B4	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	27%	100%
B7IFM5	Thermosipho africanus (strain TCF52B)	44%	100%
B8GZV1	Caulobacter vibrioides (strain NA1000 / CB15N)	43%	100%
B9KPJ0	Cereibacter sphaeroides (strain KD131 / KCTC 12085)	42%	100%
C9ZPE9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	92%
D0A464	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	94%
D0A6B7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	80%	81%
E0Z5R2	Leishmania donovani	97%	100%
E9AMI3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	96%
E9ATX4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	54%	99%
E9B430	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
O08618	Rattus norvegicus	30%	96%
O26877	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	29%	100%
O28853	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	27%	100%
O29666	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	29%	100%
O33924	Corynebacterium ammoniagenes	42%	100%
O52958	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	31%	100%
O59586	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	28%	100%
O60256	Homo sapiens	30%	96%
O64888	Arabidopsis thaliana	38%	90%
O67556	Aquifex aeolicus (strain VF5)	41%	100%
O94413	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	100%
P09330	Rattus norvegicus	41%	100%
P0A1V6	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	40%	100%
P0A1V7	Salmonella typhi	40%	100%
P0A717	Escherichia coli (strain K12)	40%	100%
P0A718	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	40%	100%
P0A719	Escherichia coli O157:H7	40%	100%
P0DB98	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	40%	100%
P0DB99	Streptococcus pyogenes serotype M3 (strain SSI-1)	40%	100%
P0DC00	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	35%	100%
P0DC01	Streptococcus pyogenes serotype M3 (strain SSI-1)	35%	100%
P11908	Homo sapiens	41%	100%
P14193	Bacillus subtilis (strain 168)	42%	100%
P21108	Homo sapiens	40%	100%
P38063	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P38620	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P38689	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P42816	Bacillus caldolyticus	42%	100%
P44328	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	41%	100%
P46585	Candida albicans	38%	100%
P47304	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	36%	100%
P56184	Helicobacter pylori (strain ATCC 700392 / 26695)	44%	100%
P57266	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	39%	100%
P59512	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	39%	100%
P60891	Homo sapiens	41%	100%
P60892	Rattus norvegicus	41%	100%
P65233	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	42%	100%
P65234	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	44%	100%
P65235	Neisseria meningitidis serogroup B (strain MC58)	44%	100%
P65236	Staphylococcus aureus (strain Mu50 / ATCC 700699)	42%	100%
P65237	Staphylococcus aureus (strain N315)	42%	100%
P65238	Staphylococcus aureus (strain MW2)	42%	100%
P65239	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	40%	100%
P65240	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	40%	100%
P65241	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	33%	100%
P65242	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	33%	100%
P65243	Streptococcus pyogenes serotype M1	40%	100%
P65245	Streptococcus pyogenes serotype M18 (strain MGAS8232)	40%	100%
P75044	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	39%	100%
P87171	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P9WKE2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	42%	100%
P9WKE3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	42%	100%
Q08DW2	Bos taurus	30%	100%
Q0ARN5	Maricaulis maris (strain MCS10)	44%	100%
Q0BPP0	Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)	42%	100%
Q0C5A1	Hyphomonas neptunium (strain ATCC 15444)	42%	100%
Q14558	Homo sapiens	29%	100%
Q1LTH2	Baumannia cicadellinicola subsp. Homalodisca coagulata	40%	100%
Q27680	Leishmania donovani	56%	96%
Q28DH0	Xenopus tropicalis	29%	99%
Q2HJ58	Bos taurus	41%	100%
Q42581	Arabidopsis thaliana	38%	88%
Q42583	Arabidopsis thaliana	38%	89%
Q48793	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	41%	100%
Q49V09	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	42%	100%
Q4J9A6	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	26%	100%
Q4L3F7	Staphylococcus haemolyticus (strain JCSC1435)	42%	100%
Q4Q0M2	Leishmania major	55%	100%
Q4Q3Z4	Leishmania major	97%	100%
Q4QI56	Leishmania major	56%	100%
Q4R4R7	Macaca fascicularis	41%	100%
Q4R4U3	Macaca fascicularis	40%	100%
Q54PA9	Dictyostelium discoideum	41%	100%
Q54QU9	Dictyostelium discoideum	39%	100%
Q55848	Synechocystis sp. (strain PCC 6803 / Kazusa)	41%	100%
Q58761	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	32%	100%
Q59988	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	40%	100%
Q5HIH5	Staphylococcus aureus (strain COL)	42%	100%
Q5HRQ5	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	41%	100%
Q5R8F8	Pongo abelii	41%	100%
Q5RBA8	Pongo abelii	30%	96%
Q5RFJ7	Pongo abelii	41%	100%
Q5XC85	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	35%	100%
Q5XEL0	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	40%	100%
Q5XGI0	Xenopus tropicalis	41%	100%
Q5ZI49	Gallus gallus	39%	100%
Q5ZL26	Gallus gallus	30%	96%
Q63468	Rattus norvegicus	29%	100%
Q63XL8	Burkholderia pseudomallei (strain K96243)	45%	100%
Q69XQ6	Oryza sativa subsp. japonica	38%	89%
Q6AJL7	Desulfotalea psychrophila (strain LSv54 / DSM 12343)	45%	100%
Q6GBY8	Staphylococcus aureus (strain MSSA476)	42%	100%
Q6GJH1	Staphylococcus aureus (strain MRSA252)	42%	100%
Q6Z2L5	Oryza sativa subsp. japonica	37%	90%
Q723E1	Listeria monocytogenes serotype 4b (strain F2365)	37%	100%
Q724L4	Listeria monocytogenes serotype 4b (strain F2365)	41%	100%
Q72V73	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	41%	100%
Q75JN8	Dictyostelium discoideum	37%	100%
Q7M8J0	Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)	42%	100%
Q7MMZ1	Vibrio vulnificus (strain YJ016)	42%	100%
Q7MT83	Porphyromonas gingivalis (strain ATCC BAA-308 / W83)	39%	100%
Q7N590	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	41%	100%
Q7NM67	Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)	38%	100%
Q7NQS9	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	44%	100%
Q7U7L5	Parasynechococcus marenigrum (strain WH8102)	43%	100%
Q7UPM4	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	39%	100%
Q7V111	Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)	41%	100%
Q7V6S2	Prochlorococcus marinus (strain MIT 9313)	44%	100%
Q7VBH4	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	42%	100%
Q7VFY9	Helicobacter hepaticus (strain ATCC 51449 / 3B1)	46%	100%
Q7VL55	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	41%	100%
Q7VR76	Blochmannia floridanus	39%	100%
Q7VUH1	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	44%	100%
Q7W181	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	44%	100%
Q7WNY4	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	44%	100%
Q7ZXC9	Xenopus laevis	41%	100%
Q81J97	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	42%	100%
Q81VZ0	Bacillus anthracis	42%	100%
Q82HE7	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	40%	100%
Q82TQ4	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	45%	100%
Q82ZA5	Enterococcus faecalis (strain ATCC 700802 / V583)	40%	100%
Q832Z5	Enterococcus faecalis (strain ATCC 700802 / V583)	38%	100%
Q83AQ1	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	43%	100%
Q83TK1	Listeria welshimeri	41%	100%
Q83YI7	Listeria ivanovii	41%	100%
Q87A22	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	41%	100%
Q87RN8	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	41%	100%
Q888C6	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	41%	100%
Q88PX6	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	41%	100%
Q88VA5	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	36%	100%
Q88Z84	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	40%	100%
Q899I8	Clostridium tetani (strain Massachusetts / E88)	42%	100%
Q89DJ1	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	43%	100%
Q8CQU7	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	41%	100%
Q8DFF5	Vibrio vulnificus (strain CMCP6)	42%	100%
Q8DU94	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	34%	100%
Q8DWM2	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	40%	100%
Q8DZK4	Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)	36%	100%
Q8E2H0	Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)	39%	100%
Q8E568	Streptococcus agalactiae serotype III (strain NEM316)	36%	100%
Q8E7X8	Streptococcus agalactiae serotype III (strain NEM316)	39%	100%
Q8EAQ9	Shewanella oneidensis (strain MR-1)	41%	100%
Q8EU34	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	40%	100%
Q8EZN0	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	41%	100%
Q8FQV2	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	42%	100%
Q8FZF0	Brucella suis biovar 1 (strain 1330)	42%	100%
Q8G5P2	Bifidobacterium longum (strain NCC 2705)	38%	100%
Q8K9X2	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	39%	100%
Q8KCQ2	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	39%	100%
Q8NRU9	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	40%	100%
Q8P137	Streptococcus pyogenes serotype M18 (strain MGAS8232)	35%	100%
Q8PC63	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	42%	100%
Q8PNU0	Xanthomonas axonopodis pv. citri (strain 306)	42%	100%
Q8PUX3	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	27%	100%
Q8R574	Mus musculus	30%	96%
Q8R753	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)	41%	100%
Q8RHM2	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	41%	100%
Q8TRK8	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	28%	100%
Q8TUT6	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	30%	100%
Q8U458	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	31%	100%
Q8UDA9	Agrobacterium fabrum (strain C58 / ATCC 33970)	42%	100%
Q8XHJ4	Clostridium perfringens (strain 13 / Type A)	44%	100%
Q8Y2E1	Ralstonia solanacearum (strain GMI1000)	45%	100%
Q8Y9L8	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	36%	100%
Q8YIG1	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	42%	100%
Q8YN97	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	39%	100%
Q8ZEY2	Yersinia pestis	40%	100%
Q8ZU24	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	28%	100%
Q92EF1	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	36%	100%
Q92F68	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	41%	100%
Q92N73	Rhizobium meliloti (strain 1021)	42%	100%
Q93Z66	Arabidopsis thaliana	22%	87%
Q973F3	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	27%	100%
Q97CA5	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	24%	100%
Q97E93	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	40%	100%
Q97Z86	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	29%	100%
Q98HW3	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	43%	100%
Q98R83	Mycoplasmopsis pulmonis (strain UAB CTIP)	37%	100%
Q99ZR0	Streptococcus pyogenes serotype M1	35%	100%
Q9AAV6	Caulobacter vibrioides (strain ATCC 19089 / CB15)	43%	100%
Q9CD45	Mycobacterium leprae (strain TN)	42%	100%
Q9CEI4	Lactococcus lactis subsp. lactis (strain IL1403)	32%	100%
Q9CHB8	Lactococcus lactis subsp. lactis (strain IL1403)	43%	100%
Q9CP22	Pasteurella multocida (strain Pm70)	41%	100%
Q9CS42	Mus musculus	41%	100%
Q9D0M1	Mus musculus	29%	100%
Q9D7G0	Mus musculus	41%	100%
Q9EWS0	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	34%	100%
Q9HLV6	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	24%	100%
Q9HN88	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	27%	100%
Q9HVC5	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	41%	100%
Q9K3U0	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	40%	100%
Q9KGJ5	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	42%	100%
Q9KQ22	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	42%	100%
Q9PA76	Xylella fastidiosa (strain 9a5c)	41%	100%
Q9PP15	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	42%	100%
Q9PQV0	Ureaplasma parvum serovar 3 (strain ATCC 700970)	34%	100%
Q9RUD2	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	36%	100%
Q9UY08	Pyrococcus abyssi (strain GE5 / Orsay)	29%	100%
Q9X1W3	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	41%	100%
Q9XG98	Spinacia oleracea	38%	100%
Q9XG99	Spinacia oleracea	39%	90%
Q9XGA1	Spinacia oleracea	25%	100%
Q9YAW0	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	25%	100%
Q9ZLA1	Helicobacter pylori (strain J99 / ATCC 700824)	43%	100%
V5BEF5	Trypanosoma cruzi	50%	89%
V5BQA6	Trypanosoma cruzi	54%	91%
V5DQE3	Trypanosoma cruzi	80%	98%