OCRE domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HLF7_LEIBR

TriTrypDb:

LbrM.33.1230 , LBRM2903_330017300

Length:

214

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 9

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HLF7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HLF7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	115	119	PF00656	0.580
CLV_C14_Caspase3-7	149	153	PF00656	0.542
CLV_C14_Caspase3-7	89	93	PF00656	0.578
CLV_PCSK_SKI1_1	126	130	PF00082	0.571
CLV_PCSK_SKI1_1	7	11	PF00082	0.595
DOC_CKS1_1	166	171	PF01111	0.435
DOC_PP2B_LxvP_1	84	87	PF13499	0.581
DOC_PP4_FxxP_1	187	190	PF00568	0.447
DOC_WW_Pin1_4	132	137	PF00397	0.675
DOC_WW_Pin1_4	14	19	PF00397	0.629
DOC_WW_Pin1_4	165	170	PF00397	0.669
LIG_BRCT_BRCA1_1	183	187	PF00533	0.519
LIG_FHA_1	161	167	PF00498	0.393
LIG_LIR_Apic_2	176	182	PF02991	0.614
LIG_LIR_Apic_2	184	190	PF02991	0.502
LIG_PTAP_UEV_1	40	45	PF05743	0.541
LIG_PTAP_UEV_1	48	53	PF05743	0.519
LIG_SH2_CRK	180	184	PF00017	0.365
LIG_SH2_CRK	196	200	PF00017	0.421
LIG_SH2_NCK_1	196	200	PF00017	0.421
LIG_SH2_SRC	196	199	PF00017	0.483
LIG_SH3_3	103	109	PF00018	0.677
LIG_SH3_3	152	158	PF00018	0.643
LIG_SH3_3	163	169	PF00018	0.539
LIG_SH3_3	30	36	PF00018	0.544
LIG_SH3_3	38	44	PF00018	0.523
LIG_SH3_3	46	52	PF00018	0.503
LIG_SH3_3	54	60	PF00018	0.499
LIG_SH3_3	62	68	PF00018	0.523
LIG_SH3_3	70	76	PF00018	0.576
LIG_SUMO_SIM_par_1	162	168	PF11976	0.390
LIG_TRAF2_1	173	176	PF00917	0.374
MOD_CDK_SPxK_1	132	138	PF00069	0.614
MOD_CK1_1	102	108	PF00069	0.718
MOD_CK1_1	141	147	PF00069	0.622
MOD_CK2_1	170	176	PF00069	0.363
MOD_CK2_1	91	97	PF00069	0.665
MOD_GlcNHglycan	172	175	PF01048	0.374
MOD_GlcNHglycan	3	6	PF01048	0.681
MOD_GlcNHglycan	41	44	PF01048	0.707
MOD_GlcNHglycan	49	52	PF01048	0.609
MOD_GlcNHglycan	99	102	PF01048	0.729
MOD_GSK3_1	12	19	PF00069	0.694
MOD_GSK3_1	120	127	PF00069	0.702
MOD_GSK3_1	134	141	PF00069	0.623
MOD_GSK3_1	206	213	PF00069	0.501
MOD_GSK3_1	91	98	PF00069	0.688
MOD_N-GLC_1	102	107	PF02516	0.641
MOD_N-GLC_1	118	123	PF02516	0.581
MOD_N-GLC_1	12	17	PF02516	0.607
MOD_N-GLC_1	138	143	PF02516	0.566
MOD_NEK2_1	1	6	PF00069	0.711
MOD_NEK2_1	124	129	PF00069	0.565
MOD_NMyristoyl	1	7	PF02799	0.700
MOD_Plk_1	102	108	PF00069	0.630
MOD_Plk_1	124	130	PF00069	0.567
MOD_Plk_2-3	197	203	PF00069	0.476
MOD_ProDKin_1	132	138	PF00069	0.679
MOD_ProDKin_1	14	20	PF00069	0.627
MOD_ProDKin_1	165	171	PF00069	0.658
MOD_SPalmitoyl_4	1	7	PF01529	0.700
MOD_SUMO_rev_2	144	153	PF00179	0.520
MOD_SUMO_rev_2	92	101	PF00179	0.568
TRG_ENDOCYTIC_2	196	199	PF00928	0.401

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X6J5	Leishmania donovani	49%	100%
A4I8W8	Leishmania infantum	49%	100%
E9B3T7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	100%