LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HLE9_LEIBR
TriTrypDb:
LbrM.33.1140 , LBRM2903_330016100
Length:
1149

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005634 nucleus 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4HLE9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HLE9

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 67 71 PF00656 0.551
CLV_C14_Caspase3-7 705 709 PF00656 0.542
CLV_NRD_NRD_1 228 230 PF00675 0.761
CLV_NRD_NRD_1 254 256 PF00675 0.685
CLV_NRD_NRD_1 310 312 PF00675 0.612
CLV_NRD_NRD_1 496 498 PF00675 0.462
CLV_NRD_NRD_1 598 600 PF00675 0.484
CLV_NRD_NRD_1 89 91 PF00675 0.668
CLV_NRD_NRD_1 92 94 PF00675 0.669
CLV_NRD_NRD_1 95 97 PF00675 0.641
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I5H2 Leptomonas seymouri 45% 94%
A0A3S7X6I6 Leishmania donovani 70% 98%
A4I8V8 Leishmania infantum 70% 98%
E9B3S7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 69% 98%
Q4Q497 Leishmania major 71% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS