Putative RNA-binding protein RGGm

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MRB1-associated protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HL62_LEIBR

TriTrypDb:

LbrM.33.0260 , LBRM2903_310012100

Length:

183

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HL62

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HL62

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	4
GO:0003723	RNA binding	4	4
GO:0005488	binding	1	4
GO:0097159	organic cyclic compound binding	2	4
GO:1901363	heterocyclic compound binding	2	4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.456
CLV_NRD_NRD_1	144	146	PF00675	0.474
CLV_NRD_NRD_1	157	159	PF00675	0.476
CLV_NRD_NRD_1	166	168	PF00675	0.487
CLV_NRD_NRD_1	42	44	PF00675	0.519
CLV_NRD_NRD_1	6	8	PF00675	0.617
CLV_PCSK_KEX2_1	144	146	PF00082	0.520
CLV_PCSK_KEX2_1	166	168	PF00082	0.491
CLV_PCSK_KEX2_1	42	44	PF00082	0.519
CLV_PCSK_KEX2_1	6	8	PF00082	0.617
CLV_PCSK_PC7_1	2	8	PF00082	0.614
CLV_PCSK_SKI1_1	114	118	PF00082	0.244
DEG_Nend_UBRbox_1	1	4	PF02207	0.611
DOC_MAPK_gen_1	132	141	PF00069	0.428
DOC_MAPK_gen_1	42	49	PF00069	0.513
DOC_PP4_FxxP_1	106	109	PF00568	0.444
DOC_PP4_FxxP_1	37	40	PF00568	0.526
LIG_deltaCOP1_diTrp_1	26	37	PF00928	0.531
LIG_FHA_1	126	132	PF00498	0.444
LIG_FHA_1	136	142	PF00498	0.451
LIG_FHA_2	48	54	PF00498	0.442
LIG_FHA_2	78	84	PF00498	0.479
LIG_LIR_Apic_2	105	109	PF02991	0.444
LIG_LIR_Apic_2	36	40	PF02991	0.525
LIG_LIR_Gen_1	75	85	PF02991	0.444
LIG_LIR_Gen_1	90	97	PF02991	0.444
LIG_LIR_Nem_3	75	81	PF02991	0.444
LIG_LIR_Nem_3	90	96	PF02991	0.444
LIG_Pex14_2	93	97	PF04695	0.444
LIG_SH2_STAT5	130	133	PF00017	0.440
LIG_SUMO_SIM_par_1	136	143	PF11976	0.447
LIG_SUMO_SIM_par_1	45	50	PF11976	0.497
MOD_CK1_1	177	183	PF00069	0.587
MOD_CK1_1	70	76	PF00069	0.444
MOD_CK2_1	119	125	PF00069	0.444
MOD_CK2_1	47	53	PF00069	0.460
MOD_GlcNHglycan	11	14	PF01048	0.673
MOD_GlcNHglycan	69	72	PF01048	0.244
MOD_GlcNHglycan	97	100	PF01048	0.244
MOD_GSK3_1	174	181	PF00069	0.481
MOD_GSK3_1	70	77	PF00069	0.444
MOD_NEK2_1	1	6	PF00069	0.679
MOD_NEK2_1	140	145	PF00069	0.451
MOD_NEK2_1	47	52	PF00069	0.459
MOD_PKA_2	1	7	PF00069	0.712
MOD_PKB_1	7	15	PF00069	0.616
MOD_Plk_1	135	141	PF00069	0.448
MOD_Plk_1	73	79	PF00069	0.480
MOD_Plk_1	89	95	PF00069	0.457
MOD_Plk_4	125	131	PF00069	0.444
MOD_Plk_4	135	141	PF00069	0.448
TRG_DiLeu_BaEn_1	136	141	PF01217	0.447
TRG_ER_diArg_1	155	158	PF00400	0.461
TRG_ER_diArg_1	41	43	PF00400	0.526
TRG_ER_diArg_1	5	7	PF00400	0.624
TRG_Pf-PMV_PEXEL_1	114	118	PF00026	0.244
TRG_Pf-PMV_PEXEL_1	145	149	PF00026	0.515

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A422NG79	Trypanosoma rangeli	80%	100%
A4HJ16	Leishmania braziliensis	99%	100%