LeishMANIAdb
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STI1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
STI1 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HL59_LEIBR
TriTrypDb:
LbrM.33.0230 , LBRM2903_330007200 *
Length:
132

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
Term Name Level Count
GO:0005739 mitochondrion 5 1
GO:0020023 kinetoplast 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HL59
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HL59

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 12 16 PF00656 0.480
CLV_PCSK_KEX2_1 106 108 PF00082 0.520
CLV_PCSK_PC1ET2_1 106 108 PF00082 0.520
CLV_PCSK_SKI1_1 54 58 PF00082 0.714
DEG_Nend_UBRbox_3 1 3 PF02207 0.547
DOC_USP7_MATH_1 32 36 PF00917 0.721
DOC_WW_Pin1_4 7 12 PF00397 0.539
LIG_FHA_1 62 68 PF00498 0.514
LIG_FHA_2 85 91 PF00498 0.651
MOD_CDK_SPxxK_3 7 14 PF00069 0.611
MOD_CK2_1 116 122 PF00069 0.581
MOD_Cter_Amidation 48 51 PF01082 0.554
MOD_GlcNHglycan 118 121 PF01048 0.721
MOD_GlcNHglycan 22 25 PF01048 0.558
MOD_GSK3_1 16 23 PF00069 0.661
MOD_N-GLC_1 7 12 PF02516 0.615
MOD_NEK2_1 1 6 PF00069 0.618
MOD_NEK2_1 20 25 PF00069 0.423
MOD_Plk_1 79 85 PF00069 0.659
MOD_Plk_4 16 22 PF00069 0.713
MOD_ProDKin_1 7 13 PF00069 0.537
MOD_SUMO_rev_2 122 130 PF00179 0.544
MOD_SUMO_rev_2 59 64 PF00179 0.466
MOD_SUMO_rev_2 98 108 PF00179 0.583

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4KJX2 Bodo saltans 38% 69%
A0A3S7X6E1 Leishmania donovani 82% 94%
Q4Q4K1 Leishmania major 86% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS