Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

WD domain, G-beta repeat, putative

Species:

Leishmania braziliensis

UniProt:

A4HL42_LEIBR

TriTrypDb:

LbrM.33.0060 , LBRM2903_330005500

Length:

442

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	9
GO:0032991	protein-containing complex	1	9
GO:0043226	organelle	2	9
GO:0043228	non-membrane-bounded organelle	3	9
GO:0043229	intracellular organelle	3	9
GO:0043232	intracellular non-membrane-bounded organelle	4	9
GO:0110165	cellular anatomical entity	1	9
GO:1990904	ribonucleoprotein complex	2	9

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Expansion

Sequence features

A4HL42

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HL42

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	48	52	PF00656	0.747
CLV_NRD_NRD_1	187	189	PF00675	0.420
CLV_NRD_NRD_1	410	412	PF00675	0.318
CLV_PCSK_KEX2_1	410	412	PF00082	0.318
CLV_PCSK_SKI1_1	252	256	PF00082	0.229
CLV_PCSK_SKI1_1	411	415	PF00082	0.315
DEG_APCC_DBOX_1	410	418	PF00400	0.445
DOC_MAPK_gen_1	107	115	PF00069	0.396
DOC_MAPK_gen_1	410	416	PF00069	0.303
DOC_PP1_RVXF_1	347	354	PF00149	0.473

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6C2	Leptomonas seymouri	22%	100%
A0A0N1IHN2	Leptomonas seymouri	24%	85%
A0A0N1PC28	Leptomonas seymouri	74%	100%
A0A0S4IWG1	Bodo saltans	21%	90%
A0A0S4JA64	Bodo saltans	24%	75%
A0A0S4JL38	Bodo saltans	28%	82%
A0A0S4JPK4	Bodo saltans	25%	74%
A0A0S4JQ88	Bodo saltans	49%	100%
A0A0S4JQ93	Bodo saltans	25%	80%
A0A0S4KJ87	Bodo saltans	23%	74%

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