LeishMANIAdb
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Peptidase_S24 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Peptidase_S24 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HL38_LEIBR
TriTrypDb:
LbrM.33.0020 , LBRM2903_330005100
Length:
111

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HL38
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HL38

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 44 48 PF00082 0.383
DEG_Nend_UBRbox_2 1 3 PF02207 0.563
DOC_MAPK_gen_1 38 47 PF00069 0.428
DOC_PP2B_LxvP_1 73 76 PF13499 0.445
DOC_WW_Pin1_4 104 109 PF00397 0.409
LIG_14-3-3_CanoR_1 49 58 PF00244 0.492
LIG_FHA_1 13 19 PF00498 0.496
LIG_FHA_1 35 41 PF00498 0.522
LIG_IBAR_NPY_1 101 103 PF08397 0.306
LIG_PALB2_WD40_1 53 61 PF16756 0.534
LIG_SUMO_SIM_par_1 14 21 PF11976 0.482
LIG_TRAF2_1 68 71 PF00917 0.378
MOD_CK1_1 12 18 PF00069 0.480
MOD_CK1_1 66 72 PF00069 0.555
MOD_CK1_1 78 84 PF00069 0.571
MOD_GlcNHglycan 11 14 PF01048 0.445
MOD_GlcNHglycan 19 23 PF01048 0.404
MOD_GlcNHglycan 65 68 PF01048 0.492
MOD_GSK3_1 62 69 PF00069 0.460
MOD_NEK2_1 18 23 PF00069 0.314
MOD_NEK2_1 36 41 PF00069 0.442
MOD_NEK2_1 4 9 PF00069 0.362
MOD_Plk_4 12 18 PF00069 0.492
MOD_ProDKin_1 104 110 PF00069 0.416
MOD_SUMO_for_1 84 87 PF00179 0.424
TRG_ENDOCYTIC_2 92 95 PF00928 0.495

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKZ7 Leptomonas seymouri 68% 100%
A0A0S4KHD0 Bodo saltans 53% 100%
A0A1X0P3H9 Trypanosomatidae 61% 100%
A0A3Q8IEL8 Leishmania donovani 80% 100%
A0A3R7KVB4 Trypanosoma rangeli 56% 100%
A4I8L8 Leishmania infantum 80% 100%
C9ZPU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 55% 100%
E9B3H9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 100%
Q4Q4M1 Leishmania major 83% 100%
V5DB11 Trypanosoma cruzi 64% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS