A conserved kinetoplastid protein with N-terminal signal-anchor and an ankyrin repeat domain. The latter is related to the domain found in eukaryotic peptidyl-prolyl isomerases.
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 6 |
| NetGPI | no | yes: 0, no: 6 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0032991 | protein-containing complex | 1 | 1 |
| GO:0101031 | protein folding chaperone complex | 3 | 1 |
| GO:0140535 | intracellular protein-containing complex | 2 | 1 |
Related structures:
AlphaFold database: A4HL17
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 179 | 181 | PF00675 | 0.500 |
| CLV_PCSK_KEX2_1 | 179 | 181 | PF00082 | 0.500 |
| CLV_PCSK_SKI1_1 | 84 | 88 | PF00082 | 0.469 |
| DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.691 |
| DOC_MAPK_gen_1 | 82 | 91 | PF00069 | 0.381 |
| DOC_MAPK_MEF2A_6 | 4 | 13 | PF00069 | 0.427 |
| DOC_MAPK_RevD_3 | 164 | 180 | PF00069 | 0.374 |
| DOC_USP7_MATH_1 | 14 | 18 | PF00917 | 0.257 |
| DOC_USP7_MATH_1 | 42 | 46 | PF00917 | 0.551 |
| DOC_WW_Pin1_4 | 59 | 64 | PF00397 | 0.454 |
| DOC_WW_Pin1_4 | 72 | 77 | PF00397 | 0.480 |
| LIG_14-3-3_CanoR_1 | 154 | 160 | PF00244 | 0.342 |
| LIG_14-3-3_CanoR_1 | 28 | 35 | PF00244 | 0.404 |
| LIG_14-3-3_CanoR_1 | 4 | 11 | PF00244 | 0.508 |
| LIG_FHA_1 | 117 | 123 | PF00498 | 0.368 |
| LIG_FHA_1 | 125 | 131 | PF00498 | 0.372 |
| LIG_FHA_1 | 156 | 162 | PF00498 | 0.316 |
| LIG_FHA_1 | 189 | 195 | PF00498 | 0.259 |
| LIG_FHA_1 | 4 | 10 | PF00498 | 0.496 |
| LIG_Integrin_isoDGR_2 | 2 | 4 | PF01839 | 0.373 |
| LIG_Integrin_RGD_1 | 221 | 223 | PF01839 | 0.542 |
| LIG_LIR_Nem_3 | 23 | 27 | PF02991 | 0.319 |
| LIG_RPA_C_Fungi | 175 | 187 | PF08784 | 0.427 |
| LIG_SH2_CRK | 27 | 31 | PF00017 | 0.568 |
| LIG_SH2_STAT5 | 24 | 27 | PF00017 | 0.365 |
| LIG_SH2_STAT5 | 77 | 80 | PF00017 | 0.392 |
| LIG_SH3_3 | 163 | 169 | PF00018 | 0.468 |
| LIG_SH3_3 | 46 | 52 | PF00018 | 0.639 |
| LIG_SH3_3 | 62 | 68 | PF00018 | 0.508 |
| LIG_SUMO_SIM_anti_2 | 215 | 220 | PF11976 | 0.394 |
| LIG_TRAF2_1 | 99 | 102 | PF00917 | 0.386 |
| LIG_TYR_ITIM | 25 | 30 | PF00017 | 0.397 |
| LIG_UBA3_1 | 88 | 93 | PF00899 | 0.369 |
| MOD_N-GLC_1 | 188 | 193 | PF02516 | 0.297 |
| MOD_PIKK_1 | 28 | 34 | PF00454 | 0.576 |
| MOD_PIKK_1 | 3 | 9 | PF00454 | 0.602 |
| MOD_PKA_2 | 3 | 9 | PF00069 | 0.720 |
| MOD_Plk_1 | 116 | 122 | PF00069 | 0.393 |
| MOD_Plk_4 | 117 | 123 | PF00069 | 0.474 |
| MOD_Plk_4 | 14 | 20 | PF00069 | 0.310 |
| MOD_Plk_4 | 155 | 161 | PF00069 | 0.479 |
| MOD_ProDKin_1 | 59 | 65 | PF00069 | 0.562 |
| MOD_ProDKin_1 | 72 | 78 | PF00069 | 0.592 |
| MOD_SUMO_for_1 | 130 | 133 | PF00179 | 0.291 |
| MOD_SUMO_for_1 | 92 | 95 | PF00179 | 0.287 |
| MOD_SUMO_rev_2 | 170 | 174 | PF00179 | 0.419 |
| TRG_ENDOCYTIC_2 | 27 | 30 | PF00928 | 0.567 |
| TRG_ER_diArg_1 | 178 | 180 | PF00400 | 0.355 |
| TRG_Pf-PMV_PEXEL_1 | 28 | 32 | PF00026 | 0.585 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1PAP4 | Leptomonas seymouri | 46% | 100% |
| A0A3S7X657 | Leishmania donovani | 79% | 100% |
| A4I8J8 | Leishmania infantum | 79% | 100% |
| E9B3F8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 79% | 100% |
| Q4Q4P2 | Leishmania major | 79% | 100% |