Mitochondrial inner membrane protease subunit 2

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HL11_LEIBR

TriTrypDb:

LbrM.32.3980 , LBRM2903_320049400

Length:

155

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HL11

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HL11

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
DEG_APCC_DBOX_1	19	27	PF00400	0.343
DOC_CKS1_1	79	84	PF01111	0.508
DOC_MAPK_gen_1	61	69	PF00069	0.500
DOC_PP2B_LxvP_1	67	70	PF13499	0.651
DOC_PP4_FxxP_1	11	14	PF00568	0.360
DOC_WW_Pin1_4	10	15	PF00397	0.363
DOC_WW_Pin1_4	148	153	PF00397	0.456
DOC_WW_Pin1_4	54	59	PF00397	0.485
DOC_WW_Pin1_4	75	80	PF00397	0.515
LIG_14-3-3_CanoR_1	110	118	PF00244	0.670

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3W3	Leptomonas seymouri	76%	100%
A0A1X0NRY2	Trypanosomatidae	70%	100%
A0A3Q8IGB2	Leishmania donovani	84%	100%
A0A3R7N368	Trypanosoma rangeli	59%	100%
A4I8J2	Leishmania infantum	84%	100%
D0AAM6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	100%
E9B3F2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q4P8	Leishmania major	83%	100%
V5DME5	Trypanosoma cruzi	63%	100%

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