This small protein family has no close known relatives. They might not even be membrane proteins.
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 18 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 6 |
| GO:0110165 | cellular anatomical entity | 1 | 6 |
Related structures:
AlphaFold database: A4HL00
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_PCSK_SKI1_1 | 110 | 114 | PF00082 | 0.499 |
| DEG_APCC_DBOX_1 | 59 | 67 | PF00400 | 0.657 |
| DOC_MAPK_FxFP_2 | 96 | 99 | PF00069 | 0.267 |
| DOC_PP1_RVXF_1 | 22 | 28 | PF00149 | 0.562 |
| DOC_PP4_FxxP_1 | 96 | 99 | PF00568 | 0.410 |
| DOC_PP4_MxPP_1 | 1 | 4 | PF00568 | 0.582 |
| DOC_USP7_MATH_1 | 4 | 8 | PF00917 | 0.578 |
| LIG_14-3-3_CanoR_1 | 24 | 28 | PF00244 | 0.680 |
| LIG_14-3-3_CanoR_1 | 46 | 52 | PF00244 | 0.587 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.605 |
| LIG_BIR_III_1 | 1 | 5 | PF00653 | 0.576 |
| LIG_BIR_III_3 | 1 | 5 | PF00653 | 0.576 |
| LIG_deltaCOP1_diTrp_1 | 114 | 120 | PF00928 | 0.446 |
| LIG_FHA_1 | 132 | 138 | PF00498 | 0.469 |
| LIG_LIR_Apic_2 | 119 | 123 | PF02991 | 0.381 |
| LIG_LIR_Apic_2 | 26 | 30 | PF02991 | 0.574 |
| LIG_LIR_Gen_1 | 87 | 97 | PF02991 | 0.327 |
| LIG_LIR_Nem_3 | 16 | 20 | PF02991 | 0.558 |
| LIG_LIR_Nem_3 | 49 | 54 | PF02991 | 0.603 |
| LIG_NRBOX | 76 | 82 | PF00104 | 0.380 |
| LIG_Pex14_1 | 27 | 31 | PF04695 | 0.583 |
| LIG_Pex14_2 | 13 | 17 | PF04695 | 0.652 |
| LIG_Pex14_2 | 8 | 12 | PF04695 | 0.658 |
| LIG_SH2_STAP1 | 111 | 115 | PF00017 | 0.343 |
| LIG_SH2_STAT5 | 118 | 121 | PF00017 | 0.317 |
| LIG_SH2_STAT5 | 143 | 146 | PF00017 | 0.439 |
| LIG_SH2_STAT5 | 97 | 100 | PF00017 | 0.357 |
| LIG_SH3_3 | 132 | 138 | PF00018 | 0.393 |
| LIG_SH3_3 | 96 | 102 | PF00018 | 0.326 |
| MOD_CMANNOS | 117 | 120 | PF00535 | 0.660 |
| MOD_GlcNHglycan | 74 | 77 | PF01048 | 0.262 |
| MOD_GSK3_1 | 133 | 140 | PF00069 | 0.395 |
| MOD_NEK2_1 | 47 | 52 | PF00069 | 0.580 |
| MOD_PKA_2 | 23 | 29 | PF00069 | 0.673 |
| MOD_Plk_4 | 23 | 29 | PF00069 | 0.579 |
| MOD_Plk_4 | 47 | 53 | PF00069 | 0.579 |
| TRG_ENDOCYTIC_2 | 31 | 34 | PF00928 | 0.571 |
| TRG_ENDOCYTIC_2 | 54 | 57 | PF00928 | 0.595 |
| TRG_ENDOCYTIC_2 | 89 | 92 | PF00928 | 0.311 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1IJP5 | Leptomonas seymouri | 86% | 100% |
| A0A0S4JRP2 | Bodo saltans | 66% | 100% |
| A0A1X0NRX4 | Trypanosomatidae | 67% | 100% |
| A0A3S7X678 | Leishmania donovani | 93% | 100% |
| A0A422P365 | Trypanosoma rangeli | 66% | 100% |
| A4I8I1 | Leishmania infantum | 93% | 100% |
| D0AAN5 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 71% | 100% |
| E9B3E1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 94% | 100% |
| Q4Q4R1 | Leishmania major | 93% | 100% |
| V5B5U3 | Trypanosoma cruzi | 67% | 100% |