LeishMANIAdb
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CHCH domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CHCH domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HKP9_LEIBR
TriTrypDb:
LbrM.32.2820 , LBRM2903_320035700
Length:
132

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKP9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKP9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 69 71 PF00675 0.639
CLV_PCSK_KEX2_1 69 71 PF00082 0.571
CLV_PCSK_SKI1_1 62 66 PF00082 0.698
DOC_CKS1_1 72 77 PF01111 0.574
DOC_USP7_UBL2_3 62 66 PF12436 0.698
DOC_WW_Pin1_4 16 21 PF00397 0.778
DOC_WW_Pin1_4 7 12 PF00397 0.764
DOC_WW_Pin1_4 71 76 PF00397 0.563
LIG_14-3-3_CanoR_1 48 56 PF00244 0.678
LIG_14-3-3_CanoR_1 69 73 PF00244 0.598
LIG_BIR_II_1 1 5 PF00653 0.725
LIG_FHA_2 102 108 PF00498 0.323
LIG_FHA_2 17 23 PF00498 0.748
LIG_FHA_2 83 89 PF00498 0.480
LIG_LIR_Apic_2 71 75 PF02991 0.563
LIG_LIR_Nem_3 29 33 PF02991 0.769
LIG_LIR_Nem_3 63 68 PF02991 0.693
LIG_PDZ_Class_2 127 132 PF00595 0.534
LIG_Pex14_1 72 76 PF04695 0.569
LIG_TRAF2_1 19 22 PF00917 0.612
LIG_TRAF2_1 85 88 PF00917 0.480
MOD_CK1_1 71 77 PF00069 0.603
MOD_CK2_1 101 107 PF00069 0.516
MOD_CK2_1 16 22 PF00069 0.753
MOD_CK2_1 82 88 PF00069 0.661
MOD_GlcNHglycan 11 14 PF01048 0.723
MOD_NEK2_1 34 39 PF00069 0.550
MOD_PKA_2 68 74 PF00069 0.644
MOD_ProDKin_1 16 22 PF00069 0.778
MOD_ProDKin_1 7 13 PF00069 0.764
MOD_ProDKin_1 71 77 PF00069 0.569
TRG_DiLeu_LyEn_5 29 34 PF01217 0.515
TRG_ER_diArg_1 68 70 PF00400 0.646

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PF38 Leptomonas seymouri 54% 100%
A0A1X0NRK0 Trypanosomatidae 58% 100%
A0A3Q8IH69 Leishmania donovani 82% 100%
A0A422NHY0 Trypanosoma rangeli 49% 100%
A4I880 Leishmania infantum 83% 100%
E9B338 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 100%
Q4Q516 Leishmania major 76% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS