Cyclic nucleotide-binding domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cyclic nucleotide-binding domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HKP3_LEIBR

TriTrypDb:

LbrM.32.2760 , LBRM2903_320035100

Length:

522

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKP3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKP3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	182	184	PF00675	0.790
CLV_NRD_NRD_1	197	199	PF00675	0.571
CLV_NRD_NRD_1	339	341	PF00675	0.299
CLV_NRD_NRD_1	461	463	PF00675	0.561
CLV_PCSK_KEX2_1	182	184	PF00082	0.770
CLV_PCSK_KEX2_1	197	199	PF00082	0.514
CLV_PCSK_KEX2_1	339	341	PF00082	0.299
CLV_PCSK_KEX2_1	461	463	PF00082	0.556
CLV_PCSK_SKI1_1	197	201	PF00082	0.500
CLV_PCSK_SKI1_1	284	288	PF00082	0.284

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NRJ2	Trypanosomatidae	40%	72%
A0A3R7KN76	Trypanosoma rangeli	36%	100%
D0AAE4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	74%
V5DAR5	Trypanosoma cruzi	37%	72%

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