LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HKN9_LEIBR
TriTrypDb:
LbrM.32.2720 , LBRM2903_320034600 *
Length:
1284

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0000974 Prp19 complex 2 1
GO:0005681 spliceosomal complex 3 1
GO:0005684 U2-type spliceosomal complex 4 1
GO:0032991 protein-containing complex 1 1
GO:0071007 U2-type catalytic step 2 spliceosome 4 1
GO:0071013 catalytic step 2 spliceosome 3 1
GO:0071014 post-mRNA release spliceosomal complex 4 1
GO:0140513 nuclear protein-containing complex 2 1
GO:1902494 catalytic complex 2 1
GO:1990904 ribonucleoprotein complex 2 1
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Expansion

Sequence features

A4HKN9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0000349 generation of catalytic spliceosome for first transesterification step 7 1
GO:0000375 RNA splicing, via transesterification reactions 8 7
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 9 7
GO:0000398 mRNA splicing, via spliceosome 8 7
GO:0006139 nucleobase-containing compound metabolic process 3 7
GO:0006396 RNA processing 6 7
GO:0006397 mRNA processing 7 7
GO:0006725 cellular aromatic compound metabolic process 3 7
GO:0006807 nitrogen compound metabolic process 2 7
GO:0008152 metabolic process 1 7
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 240 244 PF00656 0.507
CLV_C14_Caspase3-7 489 493 PF00656 0.553
CLV_C14_Caspase3-7 97 101 PF00656 0.479
CLV_NRD_NRD_1 1256 1258 PF00675 0.440
CLV_NRD_NRD_1 235 237 PF00675 0.422
CLV_NRD_NRD_1 249 251 PF00675 0.390
CLV_NRD_NRD_1 272 274 PF00675 0.481
CLV_NRD_NRD_1 397 399 PF00675 0.294
CLV_NRD_NRD_1 632 634 PF00675 0.436
CLV_NRD_NRD_1 668 670 PF00675 0.523
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P599 Leptomonas seymouri 52% 99%
A0A3S7X5S9 Leishmania donovani 78% 100%
A4I870 Leishmania infantum 78% 100%
E9B328 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
Q4Q526 Leishmania major 77% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS