EamA domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HKM4_LEIBR

TriTrypDb:

LbrM.32.2560 , LBRM2903_320032900

Length:

139


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

A4HKM4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKM4


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	59	63	PF00082	0.336
DEG_APCC_DBOX_1	58	66	PF00400	0.394
DEG_APCC_DBOX_1	74	82	PF00400	0.517
DEG_Nend_Nbox_1	1	3	PF02207	0.439
DOC_MAPK_MEF2A_6	34	42	PF00069	0.471
DOC_USP7_MATH_1	135	139	PF00917	0.680
DOC_USP7_MATH_1	23	27	PF00917	0.416
DOC_WW_Pin1_4	83	88	PF00397	0.515
LIG_APCC_ABBA_1	106	111	PF00400	0.327
LIG_FHA_1	102	108	PF00498	0.426
LIG_FHA_1	94	100	PF00498	0.404
LIG_LIR_Nem_3	72	77	PF02991	0.603
LIG_PDZ_Class_2	134	139	PF00595	0.672
LIG_SH2_STAT5	39	42	PF00017	0.480
LIG_SH2_STAT5	77	80	PF00017	0.529
LIG_SH3_3	129	135	PF00018	0.406
LIG_SUMO_SIM_anti_2	110	117	PF11976	0.338
LIG_SUMO_SIM_par_1	29	35	PF11976	0.294
MOD_CK1_1	101	107	PF00069	0.227
MOD_GlcNHglycan	100	103	PF01048	0.312
MOD_GlcNHglycan	15	18	PF01048	0.507
MOD_GlcNHglycan	25	28	PF01048	0.546
MOD_GlcNHglycan	34	37	PF01048	0.573
MOD_GSK3_1	107	114	PF00069	0.466
MOD_GSK3_1	79	86	PF00069	0.513
MOD_N-GLC_1	4	9	PF02516	0.570
MOD_NEK2_1	32	37	PF00069	0.428
MOD_NEK2_1	69	74	PF00069	0.464
MOD_NEK2_1	98	103	PF00069	0.309
MOD_PIKK_1	79	85	PF00454	0.607
MOD_Plk_1	111	117	PF00069	0.222
MOD_Plk_1	4	10	PF00069	0.367
MOD_Plk_2-3	43	49	PF00069	0.455
MOD_Plk_4	111	117	PF00069	0.223
MOD_Plk_4	69	75	PF00069	0.479
MOD_ProDKin_1	83	89	PF00069	0.510
TRG_DiLeu_BaEn_1	111	116	PF01217	0.284
TRG_DiLeu_BaLyEn_6	27	32	PF01217	0.294
TRG_ENDOCYTIC_2	39	42	PF00928	0.480
TRG_PTS2	1	42	PF00400	0.432


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II38	Leptomonas seymouri	78%	73%
A0A0S4IRV5	Bodo saltans	46%	78%
A0A1X0NRG8	Trypanosomatidae	50%	73%
A0A1X0NUK8	Trypanosomatidae	49%	73%
A0A3Q8IH44	Leishmania donovani	92%	100%
A0A3R7KNK3	Trypanosoma rangeli	55%	78%
A4I856	Leishmania infantum	91%	100%
D0AAC3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	87%
Q4Q542	Leishmania major	91%	100%