Putative ATP-dependent RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase, putative

Species:

Leishmania braziliensis

UniProt:

A4HKL3_LEIBR

TriTrypDb:

LbrM.32.2450 , LBRM2903_320031400

Length:

770

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HKL3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKL3

Function

Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	2
GO:0000470	maturation of LSU-rRNA	9	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006364	rRNA processing	8	2
GO:0006396	RNA processing	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0016070	RNA metabolic process	5	2
GO:0016072	rRNA metabolic process	7	2
GO:0034470	ncRNA processing	7	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034660	ncRNA metabolic process	6	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0046483	heterocycle metabolic process	3	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	15
GO:0003676	nucleic acid binding	3	15
GO:0003723	RNA binding	4	14
GO:0003824	catalytic activity	1	15
GO:0004386	helicase activity	2	15
GO:0005488	binding	1	15
GO:0005524	ATP binding	5	15
GO:0016787	hydrolase activity	2	15
GO:0017076	purine nucleotide binding	4	15
GO:0030554	adenyl nucleotide binding	5	15
GO:0032553	ribonucleotide binding	3	15
GO:0032555	purine ribonucleotide binding	4	15
GO:0032559	adenyl ribonucleotide binding	5	15
GO:0035639	purine ribonucleoside triphosphate binding	4	15
GO:0036094	small molecule binding	2	15
GO:0043167	ion binding	2	15
GO:0043168	anion binding	3	15
GO:0097159	organic cyclic compound binding	2	15
GO:0097367	carbohydrate derivative binding	2	15
GO:0140640	catalytic activity, acting on a nucleic acid	2	15
GO:0140657	ATP-dependent activity	1	15
GO:1901265	nucleoside phosphate binding	3	15
GO:1901363	heterocyclic compound binding	2	15
GO:0003724	RNA helicase activity	3	3
GO:0003743	translation initiation factor activity	4	3
GO:0008135	translation factor activity, RNA binding	3	3
GO:0008186	ATP-dependent activity, acting on RNA	2	3
GO:0045182	translation regulator activity	1	3
GO:0090079	translation regulator activity, nucleic acid binding	2	3
GO:0140098	catalytic activity, acting on RNA	3	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	178	182	PF00656	0.603
CLV_C14_Caspase3-7	423	427	PF00656	0.457
CLV_C14_Caspase3-7	432	436	PF00656	0.467
CLV_NRD_NRD_1	103	105	PF00675	0.658
CLV_NRD_NRD_1	128	130	PF00675	0.393
CLV_NRD_NRD_1	167	169	PF00675	0.563
CLV_NRD_NRD_1	170	172	PF00675	0.550
CLV_NRD_NRD_1	194	196	PF00675	0.490
CLV_NRD_NRD_1	269	271	PF00675	0.160
CLV_NRD_NRD_1	330	332	PF00675	0.215
CLV_NRD_NRD_1	517	519	PF00675	0.317
CLV_NRD_NRD_1	6	8	PF00675	0.520
CLV_NRD_NRD_1	724	726	PF00675	0.572
CLV_NRD_NRD_1	739	741	PF00675	0.455
CLV_NRD_NRD_1	86	88	PF00675	0.569
CLV_PCSK_FUR_1	168	172	PF00082	0.499
CLV_PCSK_KEX2_1	105	107	PF00082	0.652
CLV_PCSK_KEX2_1	128	130	PF00082	0.594
CLV_PCSK_KEX2_1	169	171	PF00082	0.676
CLV_PCSK_KEX2_1	194	196	PF00082	0.488
CLV_PCSK_KEX2_1	329	331	PF00082	0.222
CLV_PCSK_KEX2_1	517	519	PF00082	0.235
CLV_PCSK_KEX2_1	6	8	PF00082	0.525
CLV_PCSK_KEX2_1	724	726	PF00082	0.524
CLV_PCSK_KEX2_1	738	740	PF00082	0.482
CLV_PCSK_KEX2_1	86	88	PF00082	0.591
CLV_PCSK_PC1ET2_1	105	107	PF00082	0.643
CLV_PCSK_PC1ET2_1	169	171	PF00082	0.676
CLV_PCSK_PC1ET2_1	724	726	PF00082	0.530
CLV_PCSK_SKI1_1	148	152	PF00082	0.685
CLV_PCSK_SKI1_1	517	521	PF00082	0.298
DEG_APCC_DBOX_1	203	211	PF00400	0.386
DEG_APCC_DBOX_1	360	368	PF00400	0.510
DEG_APCC_DBOX_1	410	418	PF00400	0.487
DEG_APCC_DBOX_1	695	703	PF00400	0.257
DEG_APCC_DBOX_1	737	745	PF00400	0.584
DOC_ANK_TNKS_1	371	378	PF00023	0.411
DOC_CKS1_1	341	346	PF01111	0.411
DOC_CKS1_1	623	628	PF01111	0.303
DOC_CYCLIN_RxL_1	358	371	PF00134	0.446
DOC_CYCLIN_yClb1_LxF_4	618	624	PF00134	0.317
DOC_MAPK_gen_1	404	414	PF00069	0.482
DOC_MAPK_gen_1	517	524	PF00069	0.471
DOC_MAPK_MEF2A_6	644	651	PF00069	0.262
DOC_PP1_RVXF_1	251	258	PF00149	0.449
DOC_PP2B_LxvP_1	280	283	PF13499	0.452
DOC_PP2B_LxvP_1	584	587	PF13499	0.449
DOC_PP2B_LxvP_1	649	652	PF13499	0.290
DOC_PP4_FxxP_1	257	260	PF00568	0.449
DOC_PP4_FxxP_1	50	53	PF00568	0.574
DOC_PP4_FxxP_1	623	626	PF00568	0.318
DOC_USP7_MATH_1	111	115	PF00917	0.577
DOC_USP7_MATH_1	159	163	PF00917	0.704
DOC_USP7_MATH_1	400	404	PF00917	0.411
DOC_USP7_MATH_1	441	445	PF00917	0.515
DOC_USP7_MATH_1	487	491	PF00917	0.415
DOC_USP7_MATH_1	682	686	PF00917	0.323
DOC_USP7_MATH_1	89	93	PF00917	0.534
DOC_USP7_UBL2_3	4	8	PF12436	0.476
DOC_USP7_UBL2_3	465	469	PF12436	0.452
DOC_USP7_UBL2_3	726	730	PF12436	0.484
DOC_WW_Pin1_4	340	345	PF00397	0.449
DOC_WW_Pin1_4	49	54	PF00397	0.483
DOC_WW_Pin1_4	622	627	PF00397	0.305
LIG_14-3-3_CanoR_1	128	137	PF00244	0.376
LIG_14-3-3_CanoR_1	148	153	PF00244	0.483
LIG_14-3-3_CanoR_1	170	176	PF00244	0.603
LIG_14-3-3_CanoR_1	393	397	PF00244	0.450
LIG_14-3-3_CanoR_1	411	415	PF00244	0.413
LIG_14-3-3_CanoR_1	506	512	PF00244	0.459
LIG_14-3-3_CanoR_1	607	617	PF00244	0.417
LIG_14-3-3_CanoR_1	61	70	PF00244	0.478
LIG_14-3-3_CanoR_1	732	737	PF00244	0.497
LIG_14-3-3_CterR_2	766	770	PF00244	0.502
LIG_Actin_WH2_2	673	691	PF00022	0.392
LIG_APCC_ABBA_1	563	568	PF00400	0.452
LIG_BIR_III_2	486	490	PF00653	0.485
LIG_BIR_III_4	55	59	PF00653	0.591
LIG_BRCT_BRCA1_1	529	533	PF00533	0.449
LIG_BRCT_BRCA1_1	539	543	PF00533	0.449
LIG_BRCT_BRCA1_1	619	623	PF00533	0.361
LIG_BRCT_BRCA1_1	64	68	PF00533	0.571
LIG_BRCT_BRCA1_1	702	706	PF00533	0.389
LIG_Clathr_ClatBox_1	207	211	PF01394	0.364
LIG_Clathr_ClatBox_1	364	368	PF01394	0.540
LIG_deltaCOP1_diTrp_1	568	575	PF00928	0.422
LIG_eIF4E_1	131	137	PF01652	0.565
LIG_FHA_1	175	181	PF00498	0.545
LIG_FHA_1	274	280	PF00498	0.467
LIG_FHA_1	282	288	PF00498	0.462
LIG_FHA_1	289	295	PF00498	0.431
LIG_FHA_1	588	594	PF00498	0.543
LIG_FHA_1	600	606	PF00498	0.405
LIG_FHA_1	689	695	PF00498	0.257
LIG_FHA_2	130	136	PF00498	0.370
LIG_FHA_2	152	158	PF00498	0.499
LIG_FHA_2	295	301	PF00498	0.360
LIG_FHA_2	421	427	PF00498	0.566
LIG_FHA_2	623	629	PF00498	0.302
LIG_FHA_2	718	724	PF00498	0.558
LIG_IRF3_LxIS_1	417	422	PF10401	0.347
LIG_LIR_Apic_2	254	260	PF02991	0.449
LIG_LIR_Apic_2	47	53	PF02991	0.617
LIG_LIR_Apic_2	620	626	PF02991	0.352
LIG_LIR_Gen_1	239	247	PF02991	0.478
LIG_LIR_Nem_3	239	244	PF02991	0.435
LIG_LIR_Nem_3	628	634	PF02991	0.339
LIG_MLH1_MIPbox_1	64	68	PF16413	0.629
LIG_MYND_1	597	601	PF01753	0.411
LIG_PCNA_yPIPBox_3	372	386	PF02747	0.516
LIG_PCNA_yPIPBox_3	650	662	PF02747	0.293
LIG_Pex14_1	591	595	PF04695	0.449
LIG_Pex14_1	756	760	PF04695	0.371
LIG_REV1ctd_RIR_1	65	73	PF16727	0.635
LIG_RPA_C_Fungi	190	202	PF08784	0.583
LIG_SH2_CRK	241	245	PF00017	0.243
LIG_SH2_CRK	509	513	PF00017	0.354
LIG_SH2_CRK	595	599	PF00017	0.243
LIG_SH2_NCK_1	451	455	PF00017	0.484
LIG_SH2_PTP2	315	318	PF00017	0.171
LIG_SH2_SRC	595	598	PF00017	0.243
LIG_SH2_STAT3	634	637	PF00017	0.259
LIG_SH2_STAT5	131	134	PF00017	0.591
LIG_SH2_STAT5	315	318	PF00017	0.171
LIG_SH2_STAT5	509	512	PF00017	0.288
LIG_SH2_STAT5	604	607	PF00017	0.295
LIG_SH2_STAT5	634	637	PF00017	0.384
LIG_SH2_STAT5	728	731	PF00017	0.464
LIG_SH3_1	595	601	PF00018	0.243
LIG_SH3_3	338	344	PF00018	0.295
LIG_SH3_3	595	601	PF00018	0.295
LIG_SH3_3	711	717	PF00018	0.261
LIG_SH3_3	761	767	PF00018	0.566
LIG_SUMO_SIM_anti_2	185	192	PF11976	0.541
LIG_SUMO_SIM_par_1	148	155	PF11976	0.480
LIG_SUMO_SIM_par_1	363	369	PF11976	0.423
LIG_TRAF2_1	183	186	PF00917	0.612
LIG_TRAF2_1	625	628	PF00917	0.324
LIG_TRAF2_1	720	723	PF00917	0.495
LIG_UBA3_1	261	266	PF00899	0.313
LIG_WRC_WIRS_1	508	513	PF05994	0.389
MOD_CDK_SPxK_1	340	346	PF00069	0.295
MOD_CK1_1	174	180	PF00069	0.718
MOD_CK1_1	251	257	PF00069	0.243
MOD_CK1_1	387	393	PF00069	0.184
MOD_CK1_1	671	677	PF00069	0.293
MOD_CK2_1	151	157	PF00069	0.513
MOD_CK2_1	294	300	PF00069	0.171
MOD_CK2_1	402	408	PF00069	0.309
MOD_CK2_1	426	432	PF00069	0.539
MOD_CK2_1	622	628	PF00069	0.305
MOD_CK2_1	717	723	PF00069	0.509
MOD_Cter_Amidation	4	7	PF01082	0.479
MOD_GlcNHglycan	100	103	PF01048	0.590
MOD_GlcNHglycan	141	144	PF01048	0.604
MOD_GlcNHglycan	163	166	PF01048	0.557
MOD_GlcNHglycan	250	253	PF01048	0.249
MOD_GlcNHglycan	333	336	PF01048	0.300
MOD_GlcNHglycan	398	401	PF01048	0.295
MOD_GlcNHglycan	529	532	PF01048	0.389
MOD_GlcNHglycan	670	673	PF01048	0.304
MOD_GlcNHglycan	91	94	PF01048	0.570
MOD_GSK3_1	148	155	PF00069	0.688
MOD_GSK3_1	331	338	PF00069	0.370
MOD_GSK3_1	392	399	PF00069	0.295
MOD_GSK3_1	523	530	PF00069	0.295
MOD_GSK3_1	613	620	PF00069	0.465
MOD_N-GLC_1	273	278	PF02516	0.310
MOD_N-GLC_1	323	328	PF02516	0.339
MOD_N-GLC_1	749	754	PF02516	0.603
MOD_NEK2_1	137	142	PF00069	0.534
MOD_NEK2_1	396	401	PF00069	0.304
MOD_NEK2_1	412	417	PF00069	0.404
MOD_NEK2_1	419	424	PF00069	0.319
MOD_NEK2_1	524	529	PF00069	0.295
MOD_NEK2_1	537	542	PF00069	0.296
MOD_NEK2_1	706	711	PF00069	0.320
MOD_NEK2_2	265	270	PF00069	0.270
MOD_PKA_2	224	230	PF00069	0.243
MOD_PKA_2	387	393	PF00069	0.298
MOD_PKA_2	410	416	PF00069	0.458
MOD_PKA_2	475	481	PF00069	0.534
MOD_PKA_2	717	723	PF00069	0.605
MOD_PKB_1	329	337	PF00069	0.389
MOD_Plk_1	230	236	PF00069	0.389
MOD_Plk_1	273	279	PF00069	0.195
MOD_Plk_2-3	29	35	PF00069	0.547
MOD_Plk_2-3	426	432	PF00069	0.593
MOD_Plk_2-3	475	481	PF00069	0.705
MOD_Plk_4	209	215	PF00069	0.351
MOD_Plk_4	335	341	PF00069	0.302
MOD_Plk_4	392	398	PF00069	0.295
MOD_Plk_4	426	432	PF00069	0.500
MOD_Plk_4	507	513	PF00069	0.389
MOD_Plk_4	587	593	PF00069	0.335
MOD_Plk_4	617	623	PF00069	0.377
MOD_ProDKin_1	340	346	PF00069	0.295
MOD_ProDKin_1	49	55	PF00069	0.476
MOD_ProDKin_1	622	628	PF00069	0.303
MOD_SUMO_for_1	175	178	PF00179	0.498
MOD_SUMO_for_1	183	186	PF00179	0.450
TRG_DiLeu_BaEn_1	186	191	PF01217	0.553
TRG_DiLeu_BaEn_2	626	632	PF01217	0.280
TRG_DiLeu_BaEn_2	756	762	PF01217	0.534
TRG_DiLeu_BaEn_4	327	333	PF01217	0.195
TRG_DiLeu_BaEn_4	627	633	PF01217	0.311
TRG_DiLeu_BaLyEn_6	203	208	PF01217	0.383
TRG_DiLeu_BaLyEn_6	257	262	PF01217	0.335
TRG_DiLeu_BaLyEn_6	360	365	PF01217	0.390
TRG_ENDOCYTIC_2	241	244	PF00928	0.243
TRG_ENDOCYTIC_2	315	318	PF00928	0.171
TRG_ENDOCYTIC_2	509	512	PF00928	0.297
TRG_ER_diArg_1	10	13	PF00400	0.544
TRG_ER_diArg_1	127	129	PF00400	0.352
TRG_ER_diArg_1	168	171	PF00400	0.599
TRG_ER_diArg_1	329	331	PF00400	0.276
TRG_ER_diArg_1	361	364	PF00400	0.276
TRG_ER_diArg_1	557	560	PF00400	0.243
TRG_ER_diArg_1	59	62	PF00400	0.415
TRG_ER_diArg_1	738	740	PF00400	0.458
TRG_NLS_Bipartite_1	86	108	PF00514	0.709
TRG_NLS_MonoCore_2	167	172	PF00514	0.498
TRG_NLS_MonoExtC_3	103	108	PF00514	0.662
TRG_NLS_MonoExtC_3	6	11	PF00514	0.530
TRG_NLS_MonoExtN_4	104	109	PF00514	0.685
TRG_NLS_MonoExtN_4	168	173	PF00514	0.617
TRG_NLS_MonoExtN_4	4	11	PF00514	0.537
TRG_Pf-PMV_PEXEL_1	125	130	PF00026	0.346
TRG_Pf-PMV_PEXEL_1	363	368	PF00026	0.238
TRG_Pf-PMV_PEXEL_1	372	376	PF00026	0.251

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWK5	Leptomonas seymouri	73%	98%
A0A0N1I6K5	Leptomonas seymouri	35%	100%
A0A0S4IWD0	Bodo saltans	35%	100%
A0A0S4JDX4	Bodo saltans	32%	88%
A0A0S4KKU4	Bodo saltans	64%	100%
A0A1X0NVK0	Trypanosomatidae	56%	100%
A0A1X0P7S4	Trypanosomatidae	35%	100%
A0A3R7M1K3	Trypanosoma rangeli	56%	100%
A0A3S5H5X3	Leishmania donovani	28%	100%
A0A3S5H6T7	Leishmania donovani	30%	100%
A0A3S7X579	Leishmania donovani	27%	100%
A0A3S7X5R1	Leishmania donovani	83%	100%
A0A3S7XAN8	Leishmania donovani	36%	100%
A0A3S7XAT8	Leishmania donovani	30%	100%
A1CB55	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	27%	100%
A1CL59	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	28%	100%
A1D699	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	28%	100%
A1DE84	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	27%	100%
A1DNF9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	28%	95%
A2RA55	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	27%	100%
A2XVF7	Oryza sativa subsp. indica	28%	93%
A3AVH5	Oryza sativa subsp. japonica	28%	93%
A3GGE9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	29%	100%
A3LNR6	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	33%	100%
A3LWH3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	27%	100%
A3LX02	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	26%	100%
A4H481	Leishmania braziliensis	27%	100%
A4H4Y0	Leishmania braziliensis	30%	100%
A4HP48	Leishmania braziliensis	35%	100%
A4HP49	Leishmania braziliensis	30%	100%
A4HWB0	Leishmania infantum	29%	100%
A4I7M5	Leishmania infantum	27%	100%
A4I846	Leishmania infantum	83%	100%
A4IDF5	Leishmania infantum	36%	100%
A4IDF6	Leishmania infantum	30%	100%
A5DAR2	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	27%	100%
A5DGM4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	27%	100%
A5DLF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	30%	100%
A5E2I8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	27%	100%
A6R918	Ajellomyces capsulatus (strain NAm1 / WU24)	28%	100%
A6RMZ2	Botryotinia fuckeliana (strain B05.10)	30%	100%
A6RSH5	Botryotinia fuckeliana (strain B05.10)	27%	88%
A6ZPU3	Saccharomyces cerevisiae (strain YJM789)	32%	100%
A6ZZY8	Saccharomyces cerevisiae (strain YJM789)	27%	100%
A7F2S3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	28%	100%
A7F8V8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	27%	88%
A7TJ71	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	30%	100%
A7TNT1	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	27%	100%
C9ZUC4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	76%
D0A331	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D0AAB3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
E9AKE2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AM86	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AQ10	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ASV6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9AZV0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	86%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B304	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	99%
O49289	Arabidopsis thaliana	26%	91%
O60173	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
O80792	Arabidopsis thaliana	26%	91%
P0CQ82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	31%	90%
P0CQ83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	31%	90%
P0CQ84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	35%	100%
P0CQ85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	35%	100%
P15424	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
P20448	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P36120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
Q09916	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
Q0CF43	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	27%	100%
Q0D622	Oryza sativa subsp. japonica	30%	100%
Q0DBS1	Oryza sativa subsp. japonica	31%	100%
Q0DBU5	Oryza sativa subsp. japonica	29%	100%
Q0DLB9	Oryza sativa subsp. japonica	31%	100%
Q0UHM7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	24%	93%
Q0UP45	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	28%	100%
Q0UR48	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	33%	100%
Q13206	Homo sapiens	30%	88%
Q1E1R7	Coccidioides immitis (strain RS)	28%	100%
Q1E9T9	Coccidioides immitis (strain RS)	28%	100%
Q2GV49	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	25%	100%
Q2NL08	Bos taurus	31%	100%
Q2UBZ5	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	28%	100%
Q2UE66	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	28%	100%
Q4HVW2	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	28%	100%
Q4HZ68	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	28%	100%
Q4P0Y5	Ustilago maydis (strain 521 / FGSC 9021)	26%	79%
Q4P9E5	Ustilago maydis (strain 521 / FGSC 9021)	30%	100%
Q4Q1N9	Leishmania major	30%	100%
Q4Q1P0	Leishmania major	36%	100%
Q4Q552	Leishmania major	83%	99%
Q4Q5M6	Leishmania major	26%	100%
Q4QFH1	Leishmania major	30%	100%
Q4QIQ9	Leishmania major	29%	100%
Q4QJG6	Leishmania major	27%	100%
Q4WM60	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	28%	98%
Q4WV71	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	27%	100%
Q4WYJ7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	28%	100%
Q54EC2	Dictyostelium discoideum	26%	100%
Q59N29	Candida albicans (strain SC5314 / ATCC MYA-2876)	26%	100%
Q59S50	Candida albicans (strain SC5314 / ATCC MYA-2876)	27%	100%
Q5AF95	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
Q5AK59	Candida albicans (strain SC5314 / ATCC MYA-2876)	35%	100%
Q5BGX6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	99%
Q5ZBH5	Oryza sativa subsp. japonica	29%	100%
Q5ZJF6	Gallus gallus	30%	88%
Q5ZLN8	Gallus gallus	32%	100%
Q6AZV7	Xenopus laevis	31%	100%
Q6BKH3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	25%	96%
Q6BSM3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	27%	100%
Q6C193	Yarrowia lipolytica (strain CLIB 122 / E 150)	26%	100%
Q6C835	Yarrowia lipolytica (strain CLIB 122 / E 150)	30%	96%
Q6CGD1	Yarrowia lipolytica (strain CLIB 122 / E 150)	30%	100%
Q6CK32	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	29%	100%
Q6CRF4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	100%
Q6FNA2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	79%
Q6FPT7	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	31%	100%
Q6K7R9	Oryza sativa subsp. japonica	28%	95%
Q754J2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	28%	100%
Q75C76	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	32%	100%
Q7XJN0	Arabidopsis thaliana	31%	100%
Q80Y44	Mus musculus	30%	88%
Q84T03	Oryza sativa subsp. japonica	34%	100%
Q86B47	Drosophila melanogaster	30%	79%
Q873H9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	26%	100%
Q8JHJ2	Danio rerio	30%	100%
Q8K363	Mus musculus	33%	100%
Q8NHQ9	Homo sapiens	31%	100%
Q8TFL3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	100%
Q93Y39	Arabidopsis thaliana	27%	93%
Q9H8H2	Homo sapiens	32%	90%
Q9SB89	Arabidopsis thaliana	35%	100%
Q9SW44	Arabidopsis thaliana	27%	100%
Q9UTP9	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
Q9VHU1	Drosophila melanogaster	30%	100%
V5DCA1	Trypanosoma cruzi	56%	100%