LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HKI9_LEIBR
TriTrypDb:
LbrM.32.2200 , LBRM2903_320028500
Length:
110

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKI9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKI9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 106 108 PF00675 0.749
CLV_NRD_NRD_1 38 40 PF00675 0.668
CLV_PCSK_FUR_1 104 108 PF00082 0.551
CLV_PCSK_KEX2_1 106 108 PF00082 0.749
CLV_PCSK_KEX2_1 14 16 PF00082 0.602
CLV_PCSK_PC1ET2_1 14 16 PF00082 0.748
LIG_14-3-3_CanoR_1 104 110 PF00244 0.552
LIG_BIR_II_1 1 5 PF00653 0.811
LIG_SH2_STAT3 100 103 PF00017 0.550
LIG_SH2_STAT5 100 103 PF00017 0.536
LIG_SH3_3 19 25 PF00018 0.510
LIG_SH3_3 6 12 PF00018 0.772
LIG_SH3_3 73 79 PF00018 0.629
LIG_SH3_3 89 95 PF00018 0.726
MOD_CK1_1 55 61 PF00069 0.607
MOD_GlcNHglycan 32 35 PF01048 0.745
MOD_GSK3_1 52 59 PF00069 0.582
MOD_PIKK_1 58 64 PF00454 0.610
TRG_ER_diArg_1 104 107 PF00400 0.754
TRG_ER_diArg_1 17 20 PF00400 0.753

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X5P3 Leishmania donovani 63% 87%
A4I821 Leishmania infantum 66% 92%
E9B2X9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 67% 100%
Q4Q577 Leishmania major 70% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS