Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HKI6_LEIBR

TriTrypDb:

LbrM.32.2160 , LBRM2903_320028100

Length:

478

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKI6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKI6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	314	318	PF00656	0.555
CLV_C14_Caspase3-7	377	381	PF00656	0.557
CLV_C14_Caspase3-7	462	466	PF00656	0.517
CLV_C14_Caspase3-7	467	471	PF00656	0.553
CLV_NRD_NRD_1	241	243	PF00675	0.657
CLV_NRD_NRD_1	385	387	PF00675	0.678
CLV_NRD_NRD_1	391	393	PF00675	0.630
CLV_NRD_NRD_1	67	69	PF00675	0.660
CLV_PCSK_KEX2_1	385	387	PF00082	0.693
CLV_PCSK_KEX2_1	391	393	PF00082	0.652
CLV_PCSK_KEX2_1	67	69	PF00082	0.660
CLV_PCSK_SKI1_1	454	458	PF00082	0.583
DEG_Nend_UBRbox_3	1	3	PF02207	0.640
DEG_SPOP_SBC_1	275	279	PF00917	0.526
DOC_CKS1_1	36	41	PF01111	0.523
DOC_CKS1_1	87	92	PF01111	0.678
DOC_CYCLIN_yCln2_LP_2	429	435	PF00134	0.489
DOC_MAPK_gen_1	263	271	PF00069	0.666
DOC_PP4_FxxP_1	338	341	PF00568	0.728
DOC_USP7_MATH_1	134	138	PF00917	0.595
DOC_USP7_MATH_1	205	209	PF00917	0.537
DOC_USP7_MATH_1	219	223	PF00917	0.602
DOC_USP7_MATH_1	275	279	PF00917	0.539
DOC_USP7_MATH_1	311	315	PF00917	0.660
DOC_USP7_MATH_1	341	345	PF00917	0.653
DOC_USP7_MATH_1	374	378	PF00917	0.544
DOC_USP7_MATH_1	458	462	PF00917	0.466
DOC_USP7_MATH_1	5	9	PF00917	0.605
DOC_WW_Pin1_4	1	6	PF00397	0.556
DOC_WW_Pin1_4	181	186	PF00397	0.519
DOC_WW_Pin1_4	285	290	PF00397	0.583
DOC_WW_Pin1_4	321	326	PF00397	0.555
DOC_WW_Pin1_4	337	342	PF00397	0.612
DOC_WW_Pin1_4	35	40	PF00397	0.653
DOC_WW_Pin1_4	397	402	PF00397	0.549
DOC_WW_Pin1_4	471	476	PF00397	0.574
DOC_WW_Pin1_4	50	55	PF00397	0.532
DOC_WW_Pin1_4	86	91	PF00397	0.682
LIG_14-3-3_CanoR_1	226	233	PF00244	0.614
LIG_14-3-3_CanoR_1	234	239	PF00244	0.643
LIG_14-3-3_CanoR_1	242	250	PF00244	0.562
LIG_14-3-3_CanoR_1	263	271	PF00244	0.666
LIG_14-3-3_CanoR_1	308	316	PF00244	0.650
LIG_Actin_WH2_2	297	312	PF00022	0.514
LIG_BRCT_BRCA1_1	136	140	PF00533	0.719
LIG_BRCT_BRCA1_1	147	151	PF00533	0.555
LIG_BRCT_BRCA1_1	179	183	PF00533	0.502
LIG_BRCT_BRCA1_1	207	211	PF00533	0.494
LIG_BRCT_BRCA1_1	332	336	PF00533	0.652
LIG_BRCT_BRCA1_1	359	363	PF00533	0.611
LIG_CaM_IQ_9	440	456	PF13499	0.579
LIG_FHA_1	162	168	PF00498	0.578
LIG_FHA_1	275	281	PF00498	0.555
LIG_FHA_1	288	294	PF00498	0.504
LIG_FHA_1	310	316	PF00498	0.686
LIG_FHA_1	403	409	PF00498	0.519
LIG_FHA_2	112	118	PF00498	0.528
LIG_FHA_2	127	133	PF00498	0.566
LIG_FHA_2	29	35	PF00498	0.660
LIG_FHA_2	345	351	PF00498	0.646
LIG_FHA_2	465	471	PF00498	0.556
LIG_FHA_2	472	478	PF00498	0.563
LIG_FHA_2	69	75	PF00498	0.623
LIG_LIR_Apic_2	132	136	PF02991	0.488
LIG_LIR_Apic_2	335	341	PF02991	0.713
LIG_LIR_Gen_1	100	109	PF02991	0.591
LIG_LIR_Gen_1	252	261	PF02991	0.515
LIG_LIR_Gen_1	333	341	PF02991	0.509
LIG_LIR_Gen_1	360	369	PF02991	0.524
LIG_LIR_Nem_3	100	105	PF02991	0.731
LIG_LIR_Nem_3	252	256	PF02991	0.516
LIG_LIR_Nem_3	333	339	PF02991	0.654
LIG_LIR_Nem_3	360	366	PF02991	0.525
LIG_SH2_STAP1	439	443	PF00017	0.569
LIG_SH3_3	472	478	PF00018	0.578
LIG_SUMO_SIM_par_1	158	165	PF11976	0.541
LIG_TRAF2_1	152	155	PF00917	0.611
LIG_TRAF2_1	79	82	PF00917	0.551
LIG_WRC_WIRS_1	345	350	PF05994	0.716
MOD_CK1_1	100	106	PF00069	0.587
MOD_CK1_1	162	168	PF00069	0.517
MOD_CK1_1	174	180	PF00069	0.591
MOD_CK1_1	19	25	PF00069	0.516
MOD_CK1_1	194	200	PF00069	0.520
MOD_CK1_1	212	218	PF00069	0.678
MOD_CK1_1	222	228	PF00069	0.642
MOD_CK1_1	287	293	PF00069	0.545
MOD_CK1_1	337	343	PF00069	0.682
MOD_CK1_1	344	350	PF00069	0.638
MOD_CK1_1	413	419	PF00069	0.611
MOD_CK1_1	471	477	PF00069	0.576
MOD_CK1_1	6	12	PF00069	0.599
MOD_CK2_1	111	117	PF00069	0.526
MOD_CK2_1	252	258	PF00069	0.656
MOD_CK2_1	471	477	PF00069	0.576
MOD_CK2_1	76	82	PF00069	0.695
MOD_Cter_Amidation	383	386	PF01082	0.674
MOD_GlcNHglycan	102	105	PF01048	0.504
MOD_GlcNHglycan	171	174	PF01048	0.663
MOD_GlcNHglycan	179	182	PF01048	0.513
MOD_GlcNHglycan	193	196	PF01048	0.491
MOD_GlcNHglycan	217	220	PF01048	0.644
MOD_GlcNHglycan	22	25	PF01048	0.508
MOD_GlcNHglycan	228	231	PF01048	0.544
MOD_GlcNHglycan	236	239	PF01048	0.481
MOD_GlcNHglycan	243	246	PF01048	0.572
MOD_GlcNHglycan	265	268	PF01048	0.642
MOD_GlcNHglycan	301	304	PF01048	0.613
MOD_GlcNHglycan	372	375	PF01048	0.614
MOD_GlcNHglycan	412	415	PF01048	0.560
MOD_GlcNHglycan	45	48	PF01048	0.521
MOD_GlcNHglycan	7	11	PF01048	0.605
MOD_GSK3_1	1	8	PF00069	0.554
MOD_GSK3_1	122	129	PF00069	0.725
MOD_GSK3_1	15	22	PF00069	0.542
MOD_GSK3_1	171	178	PF00069	0.565
MOD_GSK3_1	205	212	PF00069	0.614
MOD_GSK3_1	215	222	PF00069	0.682
MOD_GSK3_1	259	266	PF00069	0.606
MOD_GSK3_1	28	35	PF00069	0.639
MOD_GSK3_1	326	333	PF00069	0.540
MOD_GSK3_1	337	344	PF00069	0.560
MOD_GSK3_1	354	361	PF00069	0.643
MOD_GSK3_1	370	377	PF00069	0.542
MOD_GSK3_1	397	404	PF00069	0.639
MOD_GSK3_1	464	471	PF00069	0.550
MOD_GSK3_1	82	89	PF00069	0.648
MOD_N-GLC_1	15	20	PF02516	0.526
MOD_N-GLC_1	296	301	PF02516	0.556
MOD_N-GLC_1	355	360	PF02516	0.504
MOD_NEK2_1	109	114	PF00069	0.516
MOD_NEK2_1	126	131	PF00069	0.474
MOD_NEK2_1	171	176	PF00069	0.517
MOD_NEK2_1	20	25	PF00069	0.529
MOD_NEK2_1	209	214	PF00069	0.636
MOD_NEK2_1	241	246	PF00069	0.515
MOD_NEK2_1	276	281	PF00069	0.549
MOD_NEK2_1	298	303	PF00069	0.644
MOD_NEK2_1	304	309	PF00069	0.686
MOD_NEK2_1	32	37	PF00069	0.504
MOD_NEK2_1	369	374	PF00069	0.549
MOD_NEK2_1	395	400	PF00069	0.663
MOD_NEK2_1	402	407	PF00069	0.590
MOD_NEK2_1	75	80	PF00069	0.644
MOD_NEK2_2	449	454	PF00069	0.453
MOD_PIKK_1	197	203	PF00454	0.497
MOD_PIKK_1	287	293	PF00454	0.545
MOD_PKA_1	385	391	PF00069	0.672
MOD_PKA_1	67	73	PF00069	0.625
MOD_PKA_2	222	228	PF00069	0.522
MOD_PKA_2	241	247	PF00069	0.472
MOD_PKA_2	309	315	PF00069	0.673
MOD_PKA_2	385	391	PF00069	0.680
MOD_PKA_2	42	48	PF00069	0.526
MOD_PKA_2	468	474	PF00069	0.714
MOD_PKA_2	67	73	PF00069	0.625
MOD_PKA_2	75	81	PF00069	0.634
MOD_PKB_1	282	290	PF00069	0.531
MOD_PKB_1	308	316	PF00069	0.523
MOD_Plk_1	110	116	PF00069	0.581
MOD_Plk_1	15	21	PF00069	0.526
MOD_Plk_1	197	203	PF00069	0.497
MOD_Plk_1	251	257	PF00069	0.511
MOD_Plk_1	269	275	PF00069	0.517
MOD_Plk_1	296	302	PF00069	0.567
MOD_Plk_1	334	340	PF00069	0.652
MOD_Plk_1	358	364	PF00069	0.521
MOD_Plk_1	68	74	PF00069	0.661
MOD_Plk_1	81	87	PF00069	0.583
MOD_Plk_2-3	111	117	PF00069	0.526
MOD_Plk_2-3	252	258	PF00069	0.513
MOD_Plk_4	122	128	PF00069	0.534
MOD_Plk_4	16	22	PF00069	0.525
MOD_Plk_4	162	168	PF00069	0.509
MOD_Plk_4	171	177	PF00069	0.530
MOD_Plk_4	205	211	PF00069	0.587
MOD_Plk_4	212	218	PF00069	0.617
MOD_Plk_4	341	347	PF00069	0.639
MOD_Plk_4	358	364	PF00069	0.549
MOD_Plk_4	374	380	PF00069	0.657
MOD_Plk_4	82	88	PF00069	0.763
MOD_ProDKin_1	1	7	PF00069	0.556
MOD_ProDKin_1	181	187	PF00069	0.522
MOD_ProDKin_1	285	291	PF00069	0.584
MOD_ProDKin_1	321	327	PF00069	0.554
MOD_ProDKin_1	337	343	PF00069	0.611
MOD_ProDKin_1	35	41	PF00069	0.655
MOD_ProDKin_1	397	403	PF00069	0.549
MOD_ProDKin_1	471	477	PF00069	0.576
MOD_ProDKin_1	50	56	PF00069	0.529
MOD_ProDKin_1	86	92	PF00069	0.680
TRG_DiLeu_BaLyEn_6	398	403	PF01217	0.526
TRG_ER_diArg_1	385	387	PF00400	0.578
TRG_ER_diArg_1	391	393	PF00400	0.561
TRG_ER_diArg_1	66	68	PF00400	0.586
TRG_NES_CRM1_1	97	111	PF08389	0.505
TRG_Pf-PMV_PEXEL_1	451	455	PF00026	0.593

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X5L4	Leishmania donovani	50%	100%
A4I817	Leishmania infantum	50%	100%
E9B2X5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	100%
Q4Q581	Leishmania major	53%	100%