Putative rab11B GTPase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

rab11B GTPase, putative

Species:

Leishmania braziliensis

UniProt:

A4HKH2_LEIBR

TriTrypDb:

LbrM.32.2020 , LBRM2903_320026600

Length:

219

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	1
GO:0005929	cilium	4	1
GO:0036064	ciliary basal body	3	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0110165	cellular anatomical entity	1	2
GO:0120025	plasma membrane bounded cell projection	3	1
GO:0016020	membrane	2	1

Expansion

Sequence features

A4HKH2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKH2

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006886	intracellular protein transport	4	1
GO:0008104	protein localization	4	1
GO:0009987	cellular process	1	1
GO:0015031	protein transport	4	1
GO:0033036	macromolecule localization	2	1
GO:0045184	establishment of protein localization	3	1
GO:0046907	intracellular transport	3	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0051641	cellular localization	2	1
GO:0051649	establishment of localization in cell	3	1
GO:0070727	cellular macromolecule localization	3	1
GO:0071702	organic substance transport	4	1
GO:0071705	nitrogen compound transport	4	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003824	catalytic activity	1	11
GO:0003924	GTPase activity	7	11
GO:0005488	binding	1	11
GO:0005525	GTP binding	5	11
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	11
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0017076	purine nucleotide binding	4	11
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0019001	guanyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032561	guanyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	164	168	PF00656	0.285
CLV_NRD_NRD_1	108	110	PF00675	0.268
CLV_NRD_NRD_1	21	23	PF00675	0.489
CLV_PCSK_SKI1_1	109	113	PF00082	0.250
CLV_PCSK_SKI1_1	11	15	PF00082	0.522
CLV_PCSK_SKI1_1	23	27	PF00082	0.325
CLV_PCSK_SKI1_1	6	10	PF00082	0.582
CLV_PCSK_SKI1_1	86	90	PF00082	0.351
DEG_SPOP_SBC_1	214	218	PF00917	0.518
DOC_CYCLIN_yClb5_NLxxxL_5	114	120	PF00134	0.264
DOC_MAPK_gen_1	22	30	PF00069	0.282
DOC_MAPK_JIP1_4	23	29	PF00069	0.379
DOC_MAPK_MEF2A_6	22	29	PF00069	0.309
DOC_USP7_MATH_1	166	170	PF00917	0.288
DOC_USP7_MATH_1	213	217	PF00917	0.540
DOC_USP7_UBL2_3	110	114	PF12436	0.246
DOC_USP7_UBL2_3	187	191	PF12436	0.427
LIG_14-3-3_CanoR_1	109	114	PF00244	0.246
LIG_14-3-3_CanoR_1	86	91	PF00244	0.246
LIG_APCC_ABBA_1	123	128	PF00400	0.310
LIG_BIR_II_1	1	5	PF00653	0.441
LIG_BIR_III_1	1	5	PF00653	0.415
LIG_BIR_III_3	1	5	PF00653	0.415
LIG_BRCT_BRCA1_1	148	152	PF00533	0.314
LIG_FHA_1	194	200	PF00498	0.449
LIG_FHA_1	54	60	PF00498	0.281
LIG_FHA_2	10	16	PF00498	0.526
LIG_FHA_2	66	72	PF00498	0.259
LIG_LIR_Gen_1	85	95	PF02991	0.246
LIG_LIR_Nem_3	112	116	PF02991	0.246
LIG_LIR_Nem_3	85	90	PF02991	0.379
LIG_SH2_CRK	64	68	PF00017	0.264
LIG_SH2_STAP1	57	61	PF00017	0.246
LIG_SH2_STAT5	162	165	PF00017	0.283
LIG_SH2_STAT5	49	52	PF00017	0.246
LIG_SH3_3	4	10	PF00018	0.562
LIG_SUMO_SIM_par_1	26	33	PF11976	0.246
LIG_TRAF2_1	82	85	PF00917	0.246
MOD_CK1_1	144	150	PF00069	0.355
MOD_GlcNHglycan	163	166	PF01048	0.246
MOD_GlcNHglycan	32	35	PF01048	0.281
MOD_GSK3_1	105	112	PF00069	0.251
MOD_GSK3_1	174	181	PF00069	0.379
MOD_GSK3_1	53	60	PF00069	0.271
MOD_GSK3_1	86	93	PF00069	0.400
MOD_NEK2_1	105	110	PF00069	0.246
MOD_NEK2_1	174	179	PF00069	0.300
MOD_NEK2_1	30	35	PF00069	0.277
MOD_NEK2_1	52	57	PF00069	0.260
MOD_NEK2_2	57	62	PF00069	0.246
MOD_PIKK_1	193	199	PF00454	0.444
MOD_PKA_1	109	115	PF00069	0.246
MOD_Plk_2-3	65	71	PF00069	0.324
MOD_Plk_4	57	63	PF00069	0.246
MOD_Plk_4	9	15	PF00069	0.641
MOD_Plk_4	90	96	PF00069	0.386
TRG_ENDOCYTIC_2	113	116	PF00928	0.261
TRG_ENDOCYTIC_2	49	52	PF00928	0.246
TRG_ENDOCYTIC_2	64	67	PF00928	0.246
TRG_Pf-PMV_PEXEL_1	118	122	PF00026	0.273
TRG_Pf-PMV_PEXEL_1	43	47	PF00026	0.291

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Z9	Leptomonas seymouri	26%	93%
A0A0N0P3A0	Leptomonas seymouri	30%	81%
A0A0N0P3G2	Leptomonas seymouri	26%	100%
A0A0N0P6K4	Leptomonas seymouri	31%	100%
A0A0N0P8G7	Leptomonas seymouri	31%	100%
A0A0N0P971	Leptomonas seymouri	81%	100%
A0A0N1HYV5	Leptomonas seymouri	33%	100%
A0A0N1I011	Leptomonas seymouri	31%	100%
A0A0N1I5E3	Leptomonas seymouri	26%	98%
A0A0N1I9K4	Leptomonas seymouri	26%	93%
A0A0N1IC49	Leptomonas seymouri	30%	70%
A0A0N1IJ36	Leptomonas seymouri	33%	99%
A0A0N1IL60	Leptomonas seymouri	32%	100%
A0A0N1ILN4	Leptomonas seymouri	37%	100%
A0A0N1PC08	Leptomonas seymouri	34%	100%
A0A0S4IH61	Bodo saltans	32%	70%
A0A0S4IJB7	Bodo saltans	33%	100%
A0A0S4IM06	Bodo saltans	32%	100%
A0A0S4IQG4	Bodo saltans	28%	100%
A0A0S4ISF4	Bodo saltans	77%	94%
A0A0S4IWV0	Bodo saltans	35%	100%
A0A0S4IX77	Bodo saltans	31%	100%
A0A0S4IY79	Bodo saltans	28%	100%
A0A0S4J1G8	Bodo saltans	29%	100%
A0A0S4J2B4	Bodo saltans	25%	90%
A0A0S4J6H6	Bodo saltans	31%	100%
A0A0S4J9T5	Bodo saltans	24%	89%
A0A0S4JBJ9	Bodo saltans	32%	100%
A0A0S4JDW3	Bodo saltans	32%	91%
A0A0S4JF89	Bodo saltans	34%	99%
A0A0S4JHS1	Bodo saltans	30%	96%
A0A0S4JJX5	Bodo saltans	29%	100%
A0A0S4JKI9	Bodo saltans	35%	97%
A0A0S4JQT6	Bodo saltans	26%	97%
A0A0S4JR87	Bodo saltans	26%	87%
A0A0S4JRU1	Bodo saltans	32%	100%
A0A0S4JSC1	Bodo saltans	25%	100%
A0A0S4JUQ8	Bodo saltans	24%	89%
A0A0S4JVK4	Bodo saltans	31%	82%
A0A0S4JYJ1	Bodo saltans	28%	95%
A0A0S4KHE5	Bodo saltans	37%	100%
A0A0S4KLB5	Bodo saltans	25%	100%
A0A0S4KLN8	Bodo saltans	32%	91%
A0A1X0NLK7	Trypanosomatidae	32%	94%
A0A1X0NLM1	Trypanosomatidae	33%	95%
A0A1X0NLX4	Trypanosomatidae	32%	100%
A0A1X0NN96	Trypanosomatidae	34%	100%
A0A1X0NQB8	Trypanosomatidae	33%	100%
A0A1X0NQG4	Trypanosomatidae	26%	99%
A0A1X0NR18	Trypanosomatidae	33%	100%
A0A1X0NR74	Trypanosomatidae	36%	100%
A0A1X0NRC4	Trypanosomatidae	31%	99%
A0A1X0NRE0	Trypanosomatidae	32%	100%
A0A1X0NUA8	Trypanosomatidae	75%	100%
A0A1X0NUW7	Trypanosomatidae	25%	97%
A0A1X0NVM5	Trypanosomatidae	31%	100%
A0A1X0NWF8	Trypanosomatidae	28%	100%
A0A1X0NYR7	Trypanosomatidae	32%	100%
A0A1X0P0N4	Trypanosomatidae	26%	100%
A0A1X0P1V3	Trypanosomatidae	26%	94%
A0A1X0P706	Trypanosomatidae	32%	99%
A0A3Q8I8T8	Leishmania donovani	32%	100%
A0A3Q8IC02	Leishmania donovani	31%	76%
A0A3Q8ICX9	Leishmania donovani	30%	100%
A0A3Q8IE68	Leishmania donovani	38%	100%
A0A3Q8IK84	Leishmania donovani	31%	100%
A0A3Q8IRV7	Leishmania donovani	31%	74%
A0A3R7K3A9	Trypanosoma rangeli	36%	100%
A0A3R7K3N3	Trypanosoma rangeli	33%	94%
A0A3R7KA22	Trypanosoma rangeli	29%	95%
A0A3R7KBN3	Trypanosoma rangeli	33%	100%
A0A3R7KD28	Trypanosoma rangeli	32%	100%
A0A3R7L455	Trypanosoma rangeli	32%	100%
A0A3R7L7N2	Trypanosoma rangeli	27%	100%
A0A3R7LXW6	Trypanosoma rangeli	28%	98%
A0A3R7ME44	Trypanosoma rangeli	25%	90%
A0A3R7N2H4	Trypanosoma rangeli	27%	100%
A0A3R7N3U0	Trypanosoma rangeli	23%	99%
A0A3R7N6U0	Trypanosoma rangeli	35%	80%
A0A3R7N9H9	Trypanosoma rangeli	31%	100%
A0A3R7N9V4	Trypanosoma rangeli	32%	100%
A0A3R7RHV7	Trypanosoma rangeli	24%	99%
A0A3S5H4Z2	Leishmania donovani	29%	80%
A0A3S5H5Y5	Leishmania donovani	32%	97%
A0A3S5H6H3	Leishmania donovani	26%	98%
A0A3S7WRA9	Leishmania donovani	31%	100%
A0A3S7WV84	Leishmania donovani	27%	93%
A0A3S7X3D1	Leishmania donovani	25%	93%
A0A3S7X5J2	Leishmania donovani	90%	98%
A0A422MUR1	Trypanosoma rangeli	31%	99%
A0A422N7J5	Trypanosoma rangeli	33%	76%
A0A422NH56	Trypanosoma rangeli	74%	100%
A0A422P0L6	Trypanosoma rangeli	27%	96%
A0A422P3H9	Trypanosoma rangeli	29%	96%
A2WSI7	Oryza sativa subsp. indica	32%	99%
A2Y7R5	Oryza sativa subsp. indica	31%	99%
A2YEQ6	Oryza sativa subsp. indica	32%	97%
A4H506	Leishmania braziliensis	31%	100%
A4H679	Leishmania braziliensis	34%	100%
A4H6A4	Leishmania braziliensis	32%	100%
A4H6A5	Leishmania braziliensis	26%	100%
A4H9M3	Leishmania braziliensis	26%	100%
A4HBS6	Leishmania braziliensis	30%	77%
A4HEE8	Leishmania braziliensis	30%	100%
A4HFK0	Leishmania braziliensis	37%	100%
A4HIB4	Leishmania braziliensis	26%	100%
A4HK33	Leishmania braziliensis	30%	100%
A4HKJ3	Leishmania braziliensis	31%	100%
A4HLP5	Leishmania braziliensis	31%	100%
A4HQE5	Leishmania braziliensis	33%	73%
A4HRM3	Leishmania infantum	29%	80%
A4HT72	Leishmania infantum	32%	97%
A4HUK3	Leishmania infantum	31%	100%
A4HUM8	Leishmania infantum	32%	100%
A4HUM9	Leishmania infantum	26%	99%
A4HXY7	Leishmania infantum	27%	93%
A4HZ80	Leishmania infantum	31%	76%
A4I1I6	Leishmania infantum	29%	100%
A4I5J8	Leishmania infantum	25%	93%
A4I7N3	Leishmania infantum	30%	100%
A4I7Z9	Leishmania infantum	90%	98%
A4I946	Leishmania infantum	31%	100%
A4IC86	Leishmania infantum	31%	74%
A5D7F5	Bos taurus	30%	80%
A6QR46	Bos taurus	31%	100%
B1A5Z4	Leishmania donovani	29%	100%
B6DT76	Bodo saltans	35%	100%
C4YL11	Candida albicans (strain WO-1)	30%	100%
C8VQY7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	100%
C9ZIZ1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	95%
C9ZJY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
C9ZKR6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
C9ZQX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	91%
C9ZUL0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZVM8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
C9ZVR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
C9ZVR3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
D0A1F6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	81%
D0A3U8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	97%
D0A5C0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	95%
D0A6V4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
D0A7A9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	97%
D0A9H1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
D0A9R7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
D0AA67	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	94%
D0AA91	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E2RQ15	Canis lupus familiaris	31%	100%
E9ACA1	Leishmania major	28%	100%
E9AD53	Leishmania major	38%	100%
E9AHE8	Leishmania infantum	38%	100%
E9AL68	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	97%
E9ANA1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9ANC6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9ANC7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	99%
E9ARQ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	93%
E9AU60	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	74%
E9AV47	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	76%
E9AXM1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AYX8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9B0U3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	93%
E9B2H2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B2W1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
E9B2Y3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9B420	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9Q9D5	Mus musculus	58%	98%
F1PTE3	Canis lupus familiaris	30%	100%
G4MYS1	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	33%	100%
H9BW96	Epinephelus coioides	36%	100%
I1RMF2	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	31%	100%
O00194	Homo sapiens	30%	100%
O01803	Caenorhabditis elegans	32%	100%
O04157	Arabidopsis thaliana	30%	100%
O04486	Arabidopsis thaliana	34%	100%
O13876	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	94%
O17915	Caenorhabditis elegans	32%	100%
O18334	Drosophila melanogaster	31%	100%
O23561	Arabidopsis thaliana	33%	100%
O23657	Arabidopsis thaliana	32%	100%
O24461	Prunus armeniaca	32%	100%
O24466	Arabidopsis thaliana	29%	100%
O35509	Rattus norvegicus	33%	100%
O35963	Mus musculus	32%	96%
O42819	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	33%	100%
O49513	Arabidopsis thaliana	34%	100%
O49841	Arabidopsis thaliana	34%	100%
O76173	Dictyostelium discoideum	29%	100%
O80501	Arabidopsis thaliana	31%	100%
O94655	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
O95716	Homo sapiens	28%	100%
O97572	Oryctolagus cuniculus	36%	100%
P01123	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P05712	Rattus norvegicus	33%	100%
P05714	Rattus norvegicus	31%	100%
P07560	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
P09527	Rattus norvegicus	36%	100%
P0CY30	Candida albicans	30%	100%
P0CY31	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
P10536	Rattus norvegicus	38%	100%
P10948	Bos taurus	30%	100%
P10949	Bos taurus	28%	96%
P11023	Bos taurus	29%	100%
P11620	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	100%
P16976	Zea mays	35%	100%
P17608	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P17609	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
P17610	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
P18067	Canis lupus familiaris	36%	100%
P19892	Arabidopsis thaliana	33%	100%
P20336	Homo sapiens	29%	100%
P20337	Homo sapiens	30%	100%
P20338	Homo sapiens	31%	100%
P20340	Homo sapiens	31%	100%
P20790	Dictyostelium discoideum	31%	100%
P20791	Dictyostelium discoideum	29%	100%
P22125	Diplobatis ommata	37%	100%
P22127	Diplobatis ommata	32%	100%
P22129	Diplobatis ommata	33%	100%
P23640	Rattus norvegicus	31%	99%
P24408	Canis lupus familiaris	30%	100%
P24409	Canis lupus familiaris	31%	100%
P25228	Drosophila melanogaster	28%	100%
P25766	Oryza sativa subsp. japonica	32%	97%
P28185	Arabidopsis thaliana	36%	100%
P28186	Arabidopsis thaliana	31%	100%
P28187	Arabidopsis thaliana	33%	100%
P28188	Arabidopsis thaliana	38%	100%
P28748	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
P29687	Nicotiana tabacum	32%	100%
P31022	Pisum sativum	34%	100%
P31582	Arabidopsis thaliana	32%	100%
P31583	Nicotiana plumbaginifolia	32%	100%
P31584	Volvox carteri	37%	100%
P32835	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P32836	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P32939	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
P33519	Dictyostelium discoideum	31%	100%
P33723	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	38%	100%
P34139	Dictyostelium discoideum	37%	100%
P34140	Dictyostelium discoideum	34%	100%
P34143	Dictyostelium discoideum	29%	100%
P34149	Dictyostelium discoideum	29%	100%
P34213	Caenorhabditis elegans	31%	100%
P35276	Mus musculus	28%	100%
P35278	Mus musculus	36%	100%
P35279	Mus musculus	31%	100%
P35281	Rattus norvegicus	31%	100%
P35282	Mus musculus	31%	99%
P35283	Mus musculus	30%	90%
P35284	Rattus norvegicus	30%	90%
P35285	Mus musculus	32%	100%
P35286	Rattus norvegicus	31%	100%
P35288	Mus musculus	32%	92%
P35289	Rattus norvegicus	29%	100%
P35292	Mus musculus	31%	100%
P35293	Mus musculus	33%	100%
P35294	Mus musculus	34%	100%
P36017	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
P36018	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	94%
P36019	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
P36409	Dictyostelium discoideum	31%	100%
P36410	Dictyostelium discoideum	34%	100%
P36411	Dictyostelium discoideum	34%	100%
P36412	Dictyostelium discoideum	35%	100%
P36586	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
P36861	Volvox carteri	34%	100%
P36862	Volvox carteri	35%	100%
P36863	Volvox carteri	33%	100%
P36864	Volvox carteri	32%	100%
P38146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
P38542	Brugia malayi	32%	100%
P38543	Giardia intestinalis	31%	97%
P38544	Onchocerca volvulus	32%	100%
P38545	Plasmodium falciparum	32%	100%
P38546	Solanum lycopersicum	31%	99%
P38547	Solanum lycopersicum	31%	99%
P38548	Vicia faba	31%	99%
P38555	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	98%
P40392	Oryza sativa subsp. japonica	35%	100%
P40393	Oryza sativa subsp. japonica	35%	100%
P41914	Tetrahymena pyriformis	32%	98%
P41915	Tetrahymena thermophila	33%	97%
P41916	Arabidopsis thaliana	31%	99%
P41917	Arabidopsis thaliana	31%	99%
P41918	Nicotiana tabacum	31%	99%
P41919	Nicotiana tabacum	31%	99%
P41924	Yarrowia lipolytica (strain CLIB 122 / E 150)	35%	100%
P42558	Gallus gallus	34%	100%
P46629	Oryctolagus cuniculus	32%	100%
P46638	Mus musculus	33%	100%
P49103	Zea mays	32%	100%
P49104	Zea mays	32%	100%
P51146	Rattus norvegicus	34%	100%
P51147	Canis lupus familiaris	36%	100%
P51148	Homo sapiens	36%	100%
P51149	Homo sapiens	34%	100%
P51150	Mus musculus	34%	100%
P51151	Homo sapiens	31%	100%
P51152	Canis lupus familiaris	32%	100%
P51153	Homo sapiens	30%	100%
P51154	Canis lupus familiaris	31%	100%
P51156	Rattus norvegicus	33%	85%
P51157	Homo sapiens	25%	99%
P51158	Rattus norvegicus	26%	99%
P51159	Homo sapiens	32%	99%
P51996	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	99%
P52301	Xenopus laevis	34%	100%
P53994	Mus musculus	33%	100%
P54765	Lotus japonicus	31%	100%
P54766	Lotus japonicus	31%	100%
P55745	Canis lupus familiaris	31%	98%
P56371	Mus musculus	32%	100%
P57729	Homo sapiens	27%	100%
P57735	Homo sapiens	32%	100%
P59190	Homo sapiens	29%	100%
P59279	Mus musculus	32%	100%
P61017	Canis lupus familiaris	34%	100%
P61018	Homo sapiens	34%	100%
P61019	Homo sapiens	33%	100%
P61020	Homo sapiens	37%	100%
P61021	Mus musculus	37%	100%
P61026	Homo sapiens	31%	100%
P61027	Mus musculus	31%	100%
P61028	Mus musculus	30%	100%
P61105	Canis lupus familiaris	33%	100%
P61106	Homo sapiens	32%	100%
P61107	Rattus norvegicus	32%	100%
P61294	Mus musculus	31%	100%
P62490	Canis lupus familiaris	34%	100%
P62491	Homo sapiens	34%	100%
P62492	Mus musculus	34%	100%
P62493	Oryctolagus cuniculus	34%	100%
P62494	Rattus norvegicus	34%	100%
P62820	Homo sapiens	37%	100%
P62821	Mus musculus	37%	100%
P62822	Canis lupus familiaris	37%	100%
P62823	Mus musculus	29%	96%
P62824	Rattus norvegicus	29%	96%
P62825	Canis lupus familiaris	34%	100%
P62826	Homo sapiens	34%	100%
P62827	Mus musculus	34%	100%
P62828	Rattus norvegicus	34%	100%
P63011	Mus musculus	29%	100%
P63012	Rattus norvegicus	29%	100%
P70550	Rattus norvegicus	30%	100%
P79735	Danio rerio	33%	100%
P90726	Caenorhabditis briggsae	33%	100%
P91580	Ciona intestinalis	29%	100%
P92963	Arabidopsis thaliana	33%	100%
P93267	Mesembryanthemum crystallinum	30%	100%
P97950	Mus musculus	33%	92%
Q01111	Nicotiana plumbaginifolia	33%	100%
Q01890	Phytophthora infestans	36%	100%
Q01971	Oryctolagus cuniculus	33%	100%
Q05737	Zea mays	34%	100%
Q05974	Lymnaea stagnalis	35%	100%
Q05975	Lymnaea stagnalis	32%	100%
Q05976	Lymnaea stagnalis	35%	100%
Q06AU3	Sus scrofa	29%	100%
Q06AU7	Sus scrofa	37%	100%
Q08DE8	Bos taurus	29%	100%
Q0IIG8	Bos taurus	33%	100%
Q0WQN4	Arabidopsis thaliana	35%	96%
Q13636	Homo sapiens	32%	100%
Q13637	Homo sapiens	28%	97%
Q14088	Homo sapiens	33%	92%
Q15286	Homo sapiens	33%	100%
Q15771	Homo sapiens	33%	100%
Q15907	Homo sapiens	33%	100%
Q17QB7	Bos taurus	33%	100%
Q17QI8	Bos taurus	27%	93%
Q17QU4	Bos taurus	30%	100%
Q17R06	Bos taurus	31%	99%
Q1HE58	Canis lupus familiaris	31%	99%
Q1KME6	Gallus gallus	31%	100%
Q1PEX3	Arabidopsis thaliana	34%	100%
Q1RMR4	Bos taurus	29%	100%
Q1ZXE7	Dictyostelium discoideum	28%	96%
Q20365	Caenorhabditis elegans	28%	71%
Q22782	Caenorhabditis elegans	32%	100%
Q24192	Drosophila melanogaster	26%	100%
Q28IZ3	Xenopus tropicalis	33%	100%
Q29RR0	Bos taurus	33%	86%
Q2HJH2	Bos taurus	37%	100%
Q2TA29	Bos taurus	34%	100%
Q2TBH7	Bos taurus	31%	100%
Q32NQ0	Xenopus laevis	33%	100%
Q38922	Arabidopsis thaliana	32%	100%
Q39222	Arabidopsis thaliana	33%	100%
Q39433	Beta vulgaris	31%	100%
Q39434	Beta vulgaris	33%	100%
Q39570	Chlamydomonas reinhardtii	33%	100%
Q39571	Chlamydomonas reinhardtii	36%	100%
Q39572	Chlamydomonas reinhardtii	32%	100%
Q39573	Chlamydomonas reinhardtii	32%	100%
Q3MHP2	Bos taurus	33%	100%
Q3SWY9	Bos taurus	26%	99%
Q3T054	Bos taurus	34%	100%
Q3T0F5	Bos taurus	36%	100%
Q40191	Lotus japonicus	32%	97%
Q40193	Lotus japonicus	31%	100%
Q40194	Lotus japonicus	35%	100%
Q40195	Lotus japonicus	33%	100%
Q40520	Nicotiana tabacum	30%	99%
Q40521	Nicotiana tabacum	35%	100%
Q40522	Nicotiana tabacum	30%	99%
Q40523	Nicotiana tabacum	33%	100%
Q40723	Oryza sativa subsp. japonica	30%	100%
Q40787	Cenchrus ciliaris	30%	100%
Q41640	Vigna aconitifolia	30%	100%
Q43463	Glycine max	32%	100%
Q4LE85	Sus scrofa	31%	99%
Q4Q0D5	Leishmania major	31%	74%
Q4Q404	Leishmania major	32%	100%
Q4Q595	Leishmania major	90%	100%
Q4Q5N4	Leishmania major	30%	100%
Q4Q7C3	Leishmania major	25%	100%
Q4Q9V1	Leishmania major	29%	100%
Q4QCD4	Leishmania major	30%	76%
Q4QDS9	Leishmania major	27%	100%
Q4QH97	Leishmania major	26%	100%
Q4QH98	Leishmania major	32%	100%
Q4QHC3	Leishmania major	33%	100%
Q4QIN6	Leishmania major	31%	100%
Q4R4M9	Macaca fascicularis	34%	100%
Q4R4R9	Macaca fascicularis	29%	100%
Q4R4X6	Macaca fascicularis	33%	100%
Q4R8X3	Macaca fascicularis	37%	100%
Q4UB16	Theileria annulata	36%	100%
Q504M8	Mus musculus	33%	84%
Q52NJ1	Sus scrofa	34%	100%
Q52NJ2	Sus scrofa	37%	100%
Q52NJ6	Sus scrofa	32%	100%
Q53B90	Rattus norvegicus	32%	100%
Q54DA7	Dictyostelium discoideum	31%	100%
Q54E92	Dictyostelium discoideum	32%	100%
Q54FK8	Dictyostelium discoideum	29%	100%
Q54FL2	Dictyostelium discoideum	33%	100%
Q54GY8	Dictyostelium discoideum	33%	100%
Q54K69	Dictyostelium discoideum	33%	100%
Q54KM9	Dictyostelium discoideum	30%	100%
Q54NU2	Dictyostelium discoideum	34%	100%
Q54P07	Dictyostelium discoideum	26%	96%
Q54RX9	Dictyostelium discoideum	30%	100%
Q550H6	Dictyostelium discoideum	36%	98%
Q558I0	Dictyostelium discoideum	29%	100%
Q559X6	Dictyostelium discoideum	31%	100%
Q55E31	Dictyostelium discoideum	30%	84%
Q55ET3	Dictyostelium discoideum	28%	100%
Q55FK2	Dictyostelium discoideum	30%	100%
Q55FU9	Dictyostelium discoideum	27%	100%
Q58DS5	Bos taurus	31%	100%
Q58DS9	Bos taurus	37%	100%
Q58DW6	Bos taurus	30%	100%
Q5EB77	Rattus norvegicus	33%	100%
Q5JT25	Homo sapiens	30%	99%
Q5KTJ6	Mesocricetus auratus	30%	100%
Q5KTJ7	Mesocricetus auratus	30%	100%
Q5M7D1	Xenopus laevis	29%	79%
Q5R4W9	Pongo abelii	33%	100%
Q5R556	Pongo abelii	34%	100%
Q5R573	Pongo abelii	56%	96%
Q5R5H5	Pongo abelii	33%	100%
Q5R5U1	Pongo abelii	31%	100%
Q5R615	Pongo abelii	32%	96%
Q5R6B6	Pongo abelii	33%	100%
Q5R7L7	Pongo abelii	36%	100%
Q5R8Z8	Pongo abelii	32%	100%
Q5R9M7	Pongo abelii	34%	100%
Q5R9Y4	Pongo abelii	34%	100%
Q5RAV6	Pongo abelii	31%	100%
Q5RBG1	Pongo abelii	37%	100%
Q5RDE5	Pongo abelii	30%	80%
Q5RE13	Pongo abelii	37%	100%
Q5REC9	Pongo abelii	30%	100%
Q5RFI2	Pongo abelii	25%	99%
Q5U316	Rattus norvegicus	33%	100%
Q5UQ27	Acanthamoeba polyphaga mimivirus	30%	100%
Q5ZHV1	Gallus gallus	33%	96%
Q5ZHW4	Gallus gallus	37%	100%
Q5ZIT5	Gallus gallus	32%	100%
Q5ZJN2	Gallus gallus	34%	100%
Q5ZKU5	Gallus gallus	32%	100%
Q5ZLG1	Gallus gallus	33%	100%
Q61820	Mus musculus	32%	100%
Q63481	Rattus norvegicus	28%	100%
Q63941	Rattus norvegicus	30%	100%
Q63942	Rattus norvegicus	29%	100%
Q68EK7	Danio rerio	33%	100%
Q69XM7	Oryza sativa subsp. japonica	32%	97%
Q6AXT5	Rattus norvegicus	31%	98%
Q6DHC1	Danio rerio	33%	100%
Q6DUB4	Paramecium octaurelia	31%	100%
Q6FR65	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	34%	100%
Q6GL85	Xenopus tropicalis	34%	100%
Q6GQP4	Rattus norvegicus	32%	100%
Q6IMK3	Danio rerio	29%	80%
Q6IML7	Rattus norvegicus	30%	80%
Q6IMM1	Gallus gallus	29%	80%
Q6IQ22	Homo sapiens	32%	90%
Q6NYB7	Rattus norvegicus	37%	100%
Q6PHI9	Danio rerio	31%	100%
Q6PHN9	Mus musculus	33%	100%
Q74ZA9	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	100%
Q76NM7	Plasmodium falciparum (isolate 3D7)	29%	100%
Q7F7I7	Oryza sativa subsp. japonica	32%	99%
Q7GD79	Oryza sativa subsp. japonica	31%	99%
Q7RVL0	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	100%
Q7T3A4	Danio rerio	32%	100%
Q7ZYF1	Xenopus laevis	29%	80%
Q7ZZX9	Carassius auratus	33%	100%
Q86JP3	Dictyostelium discoideum	37%	100%
Q86YS6	Homo sapiens	32%	100%
Q8BHC1	Mus musculus	30%	100%
Q8BHH2	Mus musculus	32%	100%
Q8CFP6	Mus musculus	29%	80%
Q8CG50	Mus musculus	32%	100%
Q8H156	Arabidopsis thaliana	31%	99%
Q8HZJ5	Bos taurus	32%	100%
Q8K386	Mus musculus	29%	100%
Q8K586	Rattus norvegicus	32%	100%
Q8MXQ2	Dictyostelium discoideum	27%	98%
Q8MXS1	Caenorhabditis elegans	34%	100%
Q8QZZ8	Mus musculus	27%	100%
Q8TFK3	Yarrowia lipolytica (strain CLIB 122 / E 150)	28%	100%
Q8VDU1	Mus musculus	28%	93%
Q8VEA8	Mus musculus	27%	100%
Q8VHQ4	Mus musculus	28%	78%
Q8WQ53	Geodia cydonium	30%	96%
Q8WUD1	Homo sapiens	32%	100%
Q90965	Gallus gallus	33%	100%
Q91V41	Mus musculus	32%	100%
Q91YQ1	Mus musculus	28%	100%
Q91ZR1	Mus musculus	34%	100%
Q921E2	Mus musculus	32%	100%
Q923S9	Mus musculus	33%	100%
Q92928	Homo sapiens	37%	100%
Q94148	Caenorhabditis elegans	31%	100%
Q948K6	Arabidopsis thaliana	31%	100%
Q948K8	Arabidopsis thaliana	35%	100%
Q94986	Caenorhabditis elegans	25%	100%
Q95UJ0	Paramecium octaurelia	30%	100%
Q96283	Arabidopsis thaliana	33%	100%
Q969Q5	Homo sapiens	27%	100%
Q96AH8	Homo sapiens	27%	100%
Q96AX2	Homo sapiens	32%	98%
Q96DA2	Homo sapiens	30%	100%
Q96E17	Homo sapiens	28%	96%
Q96L33	Homo sapiens	28%	93%
Q96S21	Homo sapiens	28%	78%
Q99KL7	Mus musculus	26%	99%
Q99P58	Mus musculus	31%	100%
Q99P74	Rattus norvegicus	30%	100%
Q99P75	Rattus norvegicus	31%	100%
Q9C2L8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	100%
Q9C820	Arabidopsis thaliana	33%	100%
Q9C9U7	Arabidopsis thaliana	33%	94%
Q9CB01	Arabidopsis thaliana	31%	100%
Q9CZT8	Mus musculus	30%	100%
Q9D1G1	Mus musculus	37%	100%
Q9DD03	Mus musculus	31%	100%
Q9ERI2	Mus musculus	30%	99%
Q9FE79	Arabidopsis thaliana	31%	98%
Q9FGK5	Arabidopsis thaliana	35%	99%
Q9FIF9	Arabidopsis thaliana	32%	100%
Q9FJH0	Arabidopsis thaliana	35%	100%
Q9FJN8	Arabidopsis thaliana	33%	97%
Q9FK68	Arabidopsis thaliana	35%	100%
Q9FLQ3	Arabidopsis thaliana	29%	99%
Q9FPJ4	Arabidopsis thaliana	36%	100%
Q9GP33	Echinococcus multilocularis	29%	98%
Q9H082	Homo sapiens	32%	96%
Q9H0U4	Homo sapiens	37%	100%
Q9HDY0	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
Q9JKM7	Mus musculus	32%	98%
Q9LH50	Arabidopsis thaliana	31%	99%
Q9LK99	Arabidopsis thaliana	36%	100%
Q9LNK1	Arabidopsis thaliana	31%	92%
Q9LNW1	Arabidopsis thaliana	33%	100%
Q9LS94	Arabidopsis thaliana	33%	100%
Q9LW76	Arabidopsis thaliana	33%	100%
Q9LZD4	Arabidopsis thaliana	30%	100%
Q9NP72	Homo sapiens	33%	100%
Q9NP90	Homo sapiens	33%	100%
Q9NRW1	Homo sapiens	31%	100%
Q9NZQ0	Homo sapiens	30%	80%
Q9P4E9	Candida albicans (strain WO-1)	33%	100%
Q9R0M6	Mus musculus	31%	100%
Q9S810	Arabidopsis thaliana	33%	100%
Q9SEH3	Arabidopsis thaliana	36%	100%
Q9SF91	Arabidopsis thaliana	30%	100%
Q9SIP0	Arabidopsis thaliana	32%	100%
Q9SJ11	Arabidopsis thaliana	30%	100%
Q9SMQ6	Arabidopsis thaliana	33%	98%
Q9SN35	Arabidopsis thaliana	33%	100%
Q9SN68	Arabidopsis thaliana	32%	100%
Q9SRS5	Arabidopsis thaliana	34%	100%
Q9TVU5	Theileria parva	36%	100%
Q9UBK7	Homo sapiens	56%	96%
Q9UL25	Homo sapiens	31%	97%
Q9UL26	Homo sapiens	32%	100%
Q9ULC3	Homo sapiens	33%	92%
Q9ULW5	Homo sapiens	34%	86%
Q9UNT1	Homo sapiens	56%	96%
Q9VUN3	Drosophila melanogaster	31%	100%
Q9VZ23	Drosophila melanogaster	31%	100%
Q9WTL2	Mus musculus	32%	100%
Q9WVB1	Rattus norvegicus	31%	100%
Q9XER8	Gossypium hirsutum	32%	100%
Q9XI98	Arabidopsis thaliana	34%	100%
Q9YGC0	Salmo salar	34%	100%
Q9Z1Y0	Rattus norvegicus	28%	93%
Q9ZRE2	Arabidopsis thaliana	39%	100%
V5AYE3	Trypanosoma cruzi	34%	75%
V5BBM5	Trypanosoma cruzi	33%	100%
V5BCH4	Trypanosoma cruzi	32%	94%
V5BJM4	Trypanosoma cruzi	33%	84%
V5D1K6	Trypanosoma cruzi	29%	95%
V5D6P4	Trypanosoma cruzi	34%	80%
V5D9W7	Trypanosoma cruzi	33%	100%
V5DKQ7	Trypanosoma cruzi	32%	69%