F-box domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HKG8_LEIBR

TriTrypDb:

LbrM.32.1980 , LBRM2903_320026200

Length:

159

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKG8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKG8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	39	43	PF00656	0.538
CLV_NRD_NRD_1	154	156	PF00675	0.586
CLV_NRD_NRD_1	5	7	PF00675	0.648
CLV_PCSK_KEX2_1	152	154	PF00082	0.544
CLV_PCSK_KEX2_1	156	158	PF00082	0.574
CLV_PCSK_KEX2_1	5	7	PF00082	0.648
CLV_PCSK_PC1ET2_1	152	154	PF00082	0.552
CLV_PCSK_PC1ET2_1	156	158	PF00082	0.558
CLV_PCSK_SKI1_1	13	17	PF00082	0.674
DOC_USP7_MATH_1	101	105	PF00917	0.743

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P974	Leptomonas seymouri	46%	100%
A0A1X0NT35	Trypanosomatidae	33%	94%
A0A3S7X5K4	Leishmania donovani	74%	100%
A0A422NH51	Trypanosoma rangeli	33%	99%
A4I7Z5	Leishmania infantum	74%	100%
D0AA62	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9B2V7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	100%
Q4Q599	Leishmania major	69%	96%

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