Kri1_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HKG7_LEIBR

TriTrypDb:

LbrM.32.1970 , LBRM2903_320026100

Length:

244

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKG7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKG7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	145	147	PF00675	0.591
CLV_NRD_NRD_1	149	151	PF00675	0.581
CLV_NRD_NRD_1	163	165	PF00675	0.661
CLV_NRD_NRD_1	169	171	PF00675	0.584
CLV_NRD_NRD_1	19	21	PF00675	0.481
CLV_NRD_NRD_1	235	237	PF00675	0.566
CLV_NRD_NRD_1	38	40	PF00675	0.471
CLV_NRD_NRD_1	45	47	PF00675	0.523
CLV_NRD_NRD_1	66	68	PF00675	0.447
CLV_PCSK_FUR_1	35	39	PF00082	0.409
CLV_PCSK_KEX2_1	144	146	PF00082	0.595
CLV_PCSK_KEX2_1	163	165	PF00082	0.602
CLV_PCSK_KEX2_1	168	170	PF00082	0.646
CLV_PCSK_KEX2_1	19	21	PF00082	0.481
CLV_PCSK_KEX2_1	31	33	PF00082	0.510
CLV_PCSK_KEX2_1	37	39	PF00082	0.468
CLV_PCSK_KEX2_1	66	68	PF00082	0.447
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.476
CLV_PCSK_PC1ET2_1	37	39	PF00082	0.415
CLV_PCSK_PC7_1	159	165	PF00082	0.533
CLV_PCSK_SKI1_1	23	27	PF00082	0.483
CLV_PCSK_SKI1_1	236	240	PF00082	0.480
DEG_Nend_UBRbox_1	1	4	PF02207	0.600
DOC_MAPK_gen_1	26	36	PF00069	0.439
DOC_USP7_MATH_1	12	16	PF00917	0.534
DOC_USP7_MATH_1	90	94	PF00917	0.608
DOC_USP7_MATH_2	87	93	PF00917	0.537
LIG_BRCT_BRCA1_1	6	10	PF00533	0.603
LIG_FHA_1	179	185	PF00498	0.522
LIG_FHA_1	28	34	PF00498	0.442
LIG_IBAR_NPY_1	4	6	PF08397	0.432
LIG_Integrin_RGD_1	159	161	PF01839	0.512
LIG_SH2_STAT5	63	66	PF00017	0.447
LIG_SH3_3	81	87	PF00018	0.562
LIG_TRAF2_1	49	52	PF00917	0.509
MOD_CK1_1	174	180	PF00069	0.522
MOD_CK1_1	54	60	PF00069	0.460
MOD_CK2_1	118	124	PF00069	0.557
MOD_CK2_1	12	18	PF00069	0.499
MOD_CK2_1	89	95	PF00069	0.630
MOD_GlcNHglycan	120	123	PF01048	0.592
MOD_GlcNHglycan	190	193	PF01048	0.563
MOD_GlcNHglycan	205	208	PF01048	0.713
MOD_GlcNHglycan	92	95	PF01048	0.655
MOD_GSK3_1	171	178	PF00069	0.521
MOD_GSK3_1	224	231	PF00069	0.612
MOD_GSK3_1	90	97	PF00069	0.543
MOD_N-GLC_1	223	228	PF02516	0.681
MOD_NEK2_1	175	180	PF00069	0.515
MOD_NEK2_1	239	244	PF00069	0.478
MOD_NEK2_1	27	32	PF00069	0.455
MOD_NEK2_1	59	64	PF00069	0.473
MOD_PK_1	163	169	PF00069	0.516
MOD_PKA_1	163	169	PF00069	0.667
MOD_PKA_2	163	169	PF00069	0.762
MOD_Plk_1	110	116	PF00069	0.568
MOD_Plk_1	138	144	PF00069	0.510
MOD_Plk_1	51	57	PF00069	0.477
MOD_Plk_4	110	116	PF00069	0.530
MOD_Plk_4	59	65	PF00069	0.451
MOD_SUMO_rev_2	92	102	PF00179	0.534
TRG_ER_diArg_1	143	146	PF00400	0.658
TRG_ER_diArg_1	162	164	PF00400	0.486
TRG_ER_diArg_1	167	170	PF00400	0.649
TRG_ER_diArg_1	38	40	PF00400	0.455
TRG_ER_diArg_1	65	67	PF00400	0.448
TRG_NLS_Bipartite_1	19	41	PF00514	0.452
TRG_NLS_MonoExtN_4	35	41	PF00514	0.435

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFN4	Leptomonas seymouri	59%	100%
A0A3Q8IH03	Leishmania donovani	60%	95%
A4I7Z4	Leishmania infantum	61%	100%
E9B2V6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	100%
Q4Q5A0	Leishmania major	65%	99%