LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Ring_hydroxyl_A domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ring_hydroxyl_A domain-containing protein
Gene product:
Paraflagellar Rod Proteome Component 9, putative
Species:
Leishmania braziliensis
UniProt:
A4HKF5_LEIBR
TriTrypDb:
LbrM.32.1850 , LBRM2903_320024800 *
Length:
136

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0005929 cilium 4 2
GO:0042995 cell projection 2 2
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0110165 cellular anatomical entity 1 2
GO:0120025 plasma membrane bounded cell projection 3 2
GO:0031514 motile cilium 5 1

Expansion

Sequence features

A4HKF5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKF5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 102 104 PF00675 0.489
CLV_NRD_NRD_1 118 120 PF00675 0.585
CLV_NRD_NRD_1 126 128 PF00675 0.648
CLV_PCSK_KEX2_1 118 120 PF00082 0.606
CLV_PCSK_KEX2_1 126 128 PF00082 0.722
CLV_PCSK_SKI1_1 119 123 PF00082 0.538
CLV_PCSK_SKI1_1 129 133 PF00082 0.508
DOC_CYCLIN_RxL_1 113 123 PF00134 0.462
DOC_MAPK_MEF2A_6 46 53 PF00069 0.501
DOC_PP2B_LxvP_1 24 27 PF13499 0.658
LIG_BIR_II_1 1 5 PF00653 0.603
LIG_BIR_III_1 1 5 PF00653 0.565
LIG_BIR_III_3 1 5 PF00653 0.565
LIG_BRCT_BRCA1_1 27 31 PF00533 0.644
LIG_FHA_1 19 25 PF00498 0.552
LIG_LIR_Gen_1 28 39 PF02991 0.655
LIG_LIR_Nem_3 28 34 PF02991 0.654
LIG_SH2_STAT3 117 120 PF00017 0.461
LIG_SH2_STAT3 94 97 PF00017 0.453
LIG_SH2_STAT5 73 76 PF00017 0.615
LIG_TRAF2_1 27 30 PF00917 0.530
MOD_GSK3_1 18 25 PF00069 0.517
MOD_LATS_1 125 131 PF00433 0.484
MOD_NEK2_1 56 61 PF00069 0.494
MOD_PKA_2 4 10 PF00069 0.547
MOD_Plk_1 40 46 PF00069 0.639
MOD_Plk_2-3 105 111 PF00069 0.487
MOD_Plk_4 40 46 PF00069 0.639
MOD_SUMO_for_1 65 68 PF00179 0.637
TRG_DiLeu_BaEn_4 29 35 PF01217 0.531
TRG_ER_diArg_1 117 119 PF00400 0.606
TRG_ER_diArg_1 126 129 PF00400 0.721
TRG_Pf-PMV_PEXEL_1 119 123 PF00026 0.452

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I9A7 Leptomonas seymouri 64% 100%
A0A3Q8IGZ2 Leishmania donovani 68% 100%
A4I7Y3 Leishmania infantum 69% 100%
E9B2U4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 70% 100%
Q4Q5B2 Leishmania major 68% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS