YqaJ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

YqaJ-like viral recombinase domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HKD9_LEIBR

TriTrypDb:

LbrM.32.1690 , LBRM2903_320023000 , LBRM2903_320023100

Length:

619

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKD9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKD9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	394	398	PF00656	0.443
CLV_C14_Caspase3-7	516	520	PF00656	0.625
CLV_NRD_NRD_1	301	303	PF00675	0.357
CLV_NRD_NRD_1	456	458	PF00675	0.427
CLV_NRD_NRD_1	534	536	PF00675	0.280
CLV_PCSK_FUR_1	299	303	PF00082	0.327
CLV_PCSK_KEX2_1	301	303	PF00082	0.357
CLV_PCSK_KEX2_1	456	458	PF00082	0.427
CLV_PCSK_KEX2_1	534	536	PF00082	0.280
CLV_PCSK_KEX2_1	551	553	PF00082	0.447
CLV_PCSK_PC1ET2_1	551	553	PF00082	0.480
CLV_PCSK_SKI1_1	456	460	PF00082	0.430
CLV_PCSK_SKI1_1	534	538	PF00082	0.357
DEG_APCC_DBOX_1	169	177	PF00400	0.387
DEG_APCC_DBOX_1	506	514	PF00400	0.493
DOC_AGCK_PIF_2	335	340	PF00069	0.358
DOC_ANK_TNKS_1	514	521	PF00023	0.451
DOC_CKS1_1	225	230	PF01111	0.287
DOC_CKS1_1	567	572	PF01111	0.487
DOC_CYCLIN_RxL_1	531	540	PF00134	0.282
DOC_CYCLIN_yCln2_LP_2	225	231	PF00134	0.210
DOC_CYCLIN_yCln2_LP_2	348	354	PF00134	0.318
DOC_MAPK_gen_1	152	161	PF00069	0.396
DOC_MAPK_gen_1	534	541	PF00069	0.258
DOC_MAPK_MEF2A_6	154	163	PF00069	0.353
DOC_MAPK_MEF2A_6	485	493	PF00069	0.436
DOC_PP1_RVXF_1	5	11	PF00149	0.408
DOC_PP1_RVXF_1	532	539	PF00149	0.417
DOC_PP2B_LxvP_1	493	496	PF13499	0.429
DOC_PP4_FxxP_1	260	263	PF00568	0.301
DOC_PP4_FxxP_1	372	375	PF00568	0.446
DOC_USP7_MATH_1	121	125	PF00917	0.257
DOC_USP7_MATH_1	162	166	PF00917	0.378
DOC_USP7_MATH_1	169	173	PF00917	0.402
DOC_USP7_MATH_1	188	192	PF00917	0.233
DOC_USP7_MATH_1	230	234	PF00917	0.260
DOC_USP7_MATH_1	391	395	PF00917	0.474
DOC_USP7_UBL2_3	7	11	PF12436	0.301
DOC_WW_Pin1_4	119	124	PF00397	0.432
DOC_WW_Pin1_4	224	229	PF00397	0.391
DOC_WW_Pin1_4	241	246	PF00397	0.217
DOC_WW_Pin1_4	419	424	PF00397	0.359
DOC_WW_Pin1_4	555	560	PF00397	0.723
DOC_WW_Pin1_4	562	567	PF00397	0.635
DOC_WW_Pin1_4	91	96	PF00397	0.328
LIG_14-3-3_CanoR_1	118	125	PF00244	0.229
LIG_14-3-3_CanoR_1	154	160	PF00244	0.396
LIG_14-3-3_CanoR_1	168	174	PF00244	0.299
LIG_14-3-3_CanoR_1	179	185	PF00244	0.431
LIG_14-3-3_CanoR_1	218	225	PF00244	0.333
LIG_14-3-3_CanoR_1	315	321	PF00244	0.513
LIG_14-3-3_CanoR_1	32	40	PF00244	0.373
LIG_14-3-3_CanoR_1	415	425	PF00244	0.323
LIG_14-3-3_CanoR_1	451	456	PF00244	0.396
LIG_14-3-3_CanoR_1	507	511	PF00244	0.469
LIG_14-3-3_CanoR_1	527	531	PF00244	0.243
LIG_14-3-3_CanoR_1	552	559	PF00244	0.637
LIG_14-3-3_CanoR_1	601	611	PF00244	0.502
LIG_Actin_WH2_2	26	43	PF00022	0.329
LIG_AP2alpha_2	486	488	PF02296	0.298
LIG_APCC_ABBA_1	284	289	PF00400	0.316
LIG_APCC_ABBA_1	574	579	PF00400	0.569
LIG_APCC_ABBAyCdc20_2	573	579	PF00400	0.480
LIG_BIR_II_1	1	5	PF00653	0.474
LIG_BRCT_BRCA1_1	135	139	PF00533	0.272
LIG_BRCT_BRCA1_1	302	306	PF00533	0.367
LIG_BRCT_BRCA1_1	331	335	PF00533	0.430
LIG_BRCT_BRCA1_1	372	376	PF00533	0.374
LIG_BRCT_BRCA1_1	528	532	PF00533	0.282
LIG_deltaCOP1_diTrp_1	327	335	PF00928	0.434
LIG_EH_1	373	377	PF12763	0.446
LIG_FHA_1	143	149	PF00498	0.315
LIG_FHA_1	209	215	PF00498	0.265
LIG_FHA_1	420	426	PF00498	0.387
LIG_FHA_1	437	443	PF00498	0.441
LIG_FHA_1	478	484	PF00498	0.528
LIG_FHA_1	490	496	PF00498	0.409
LIG_FHA_1	580	586	PF00498	0.472
LIG_FHA_1	605	611	PF00498	0.497
LIG_FHA_2	334	340	PF00498	0.439
LIG_FHA_2	409	415	PF00498	0.416
LIG_FHA_2	432	438	PF00498	0.420
LIG_FHA_2	44	50	PF00498	0.301
LIG_FHA_2	514	520	PF00498	0.675
LIG_FHA_2	567	573	PF00498	0.488
LIG_FXI_DFP_1	335	339	PF00024	0.366
LIG_LIR_Apic_2	370	375	PF02991	0.322
LIG_LIR_Apic_2	565	570	PF02991	0.483
LIG_LIR_Gen_1	181	188	PF02991	0.217
LIG_LIR_Gen_1	283	292	PF02991	0.338
LIG_LIR_Gen_1	332	343	PF02991	0.385
LIG_LIR_Gen_1	397	408	PF02991	0.539
LIG_LIR_Gen_1	411	420	PF02991	0.386
LIG_LIR_Gen_1	486	496	PF02991	0.369
LIG_LIR_Nem_3	181	187	PF02991	0.282
LIG_LIR_Nem_3	244	249	PF02991	0.301
LIG_LIR_Nem_3	281	287	PF02991	0.309
LIG_LIR_Nem_3	332	338	PF02991	0.374
LIG_LIR_Nem_3	339	343	PF02991	0.349
LIG_LIR_Nem_3	34	39	PF02991	0.303
LIG_LIR_Nem_3	373	379	PF02991	0.396
LIG_LIR_Nem_3	397	403	PF02991	0.497
LIG_LIR_Nem_3	405	410	PF02991	0.444
LIG_LIR_Nem_3	411	416	PF02991	0.418
LIG_LIR_Nem_3	486	491	PF02991	0.333
LIG_MAD2	503	511	PF02301	0.288
LIG_NRBOX	68	74	PF00104	0.301
LIG_PCNA_yPIPBox_3	573	585	PF02747	0.476
LIG_Pex14_2	163	167	PF04695	0.234
LIG_Pex14_2	368	372	PF04695	0.469
LIG_Pex14_2	473	477	PF04695	0.463
LIG_Pex14_2	538	542	PF04695	0.289
LIG_PTB_Apo_2	77	84	PF02174	0.210
LIG_SH2_CRK	567	571	PF00017	0.487
LIG_SH2_NCK_1	413	417	PF00017	0.415
LIG_SH2_STAP1	413	417	PF00017	0.415
LIG_SH2_STAT3	266	269	PF00017	0.301
LIG_SH2_STAT5	203	206	PF00017	0.210
LIG_SH2_STAT5	250	253	PF00017	0.355
LIG_SH2_STAT5	287	290	PF00017	0.346
LIG_SH2_STAT5	36	39	PF00017	0.307
LIG_SH2_STAT5	402	405	PF00017	0.369
LIG_SH3_3	156	162	PF00018	0.412
LIG_SH3_3	226	232	PF00018	0.457
LIG_SH3_3	508	514	PF00018	0.619
LIG_SH3_3	605	611	PF00018	0.518
LIG_SUMO_SIM_par_1	238	244	PF11976	0.301
LIG_TYR_ITSM	409	416	PF00017	0.423
LIG_UBA3_1	239	243	PF00899	0.301
MOD_CDC14_SPxK_1	244	247	PF00782	0.361
MOD_CDK_SPxK_1	241	247	PF00069	0.334
MOD_CDK_SPxxK_3	566	573	PF00069	0.482
MOD_CK1_1	117	123	PF00069	0.327
MOD_CK1_1	142	148	PF00069	0.310
MOD_CK1_1	171	177	PF00069	0.436
MOD_CK1_1	178	184	PF00069	0.394
MOD_CK1_1	191	197	PF00069	0.350
MOD_CK1_1	209	215	PF00069	0.363
MOD_CK1_1	217	223	PF00069	0.419
MOD_CK1_1	252	258	PF00069	0.236
MOD_CK1_1	540	546	PF00069	0.382
MOD_CK1_1	554	560	PF00069	0.647
MOD_CK1_1	580	586	PF00069	0.672
MOD_CK1_1	606	612	PF00069	0.584
MOD_CK2_1	408	414	PF00069	0.434
MOD_CK2_1	43	49	PF00069	0.312
MOD_CK2_1	441	447	PF00069	0.436
MOD_CMANNOS	474	477	PF00535	0.471
MOD_GlcNHglycan	114	117	PF01048	0.394
MOD_GlcNHglycan	135	138	PF01048	0.361
MOD_GlcNHglycan	18	21	PF01048	0.338
MOD_GlcNHglycan	254	257	PF01048	0.236
MOD_GlcNHglycan	356	359	PF01048	0.303
MOD_GlcNHglycan	466	470	PF01048	0.377
MOD_GlcNHglycan	542	545	PF01048	0.416
MOD_GlcNHglycan	553	556	PF01048	0.548
MOD_GlcNHglycan	596	599	PF01048	0.634
MOD_GSK3_1	112	119	PF00069	0.324
MOD_GSK3_1	133	140	PF00069	0.456
MOD_GSK3_1	168	175	PF00069	0.424
MOD_GSK3_1	188	195	PF00069	0.424
MOD_GSK3_1	199	206	PF00069	0.353
MOD_GSK3_1	214	221	PF00069	0.202
MOD_GSK3_1	248	255	PF00069	0.294
MOD_GSK3_1	329	336	PF00069	0.446
MOD_GSK3_1	354	361	PF00069	0.411
MOD_GSK3_1	447	454	PF00069	0.483
MOD_GSK3_1	48	55	PF00069	0.398
MOD_GSK3_1	509	516	PF00069	0.539
MOD_GSK3_1	551	558	PF00069	0.761
MOD_GSK3_1	562	569	PF00069	0.740
MOD_GSK3_1	59	66	PF00069	0.311
MOD_GSK3_1	602	609	PF00069	0.658
MOD_N-GLC_1	142	147	PF02516	0.210
MOD_N-GLC_1	329	334	PF02516	0.431
MOD_N-GLC_1	352	357	PF02516	0.255
MOD_N-GLC_1	52	57	PF02516	0.234
MOD_N-GLC_1	577	582	PF02516	0.478
MOD_N-GLC_2	155	157	PF02516	0.210
MOD_NEK2_1	114	119	PF00069	0.469
MOD_NEK2_1	18	23	PF00069	0.340
MOD_NEK2_1	214	219	PF00069	0.352
MOD_NEK2_1	249	254	PF00069	0.378
MOD_NEK2_1	329	334	PF00069	0.431
MOD_NEK2_1	352	357	PF00069	0.424
MOD_NEK2_1	441	446	PF00069	0.401
MOD_NEK2_1	465	470	PF00069	0.439
MOD_NEK2_1	537	542	PF00069	0.417
MOD_NEK2_1	577	582	PF00069	0.647
MOD_PIKK_1	18	24	PF00454	0.301
MOD_PIKK_1	230	236	PF00454	0.244
MOD_PIKK_1	392	398	PF00454	0.418
MOD_PIKK_1	441	447	PF00454	0.345
MOD_PIKK_1	513	519	PF00454	0.604
MOD_PKA_1	551	557	PF00069	0.490
MOD_PKA_2	117	123	PF00069	0.341
MOD_PKA_2	133	139	PF00069	0.199
MOD_PKA_2	169	175	PF00069	0.321
MOD_PKA_2	178	184	PF00069	0.382
MOD_PKA_2	217	223	PF00069	0.215
MOD_PKA_2	300	306	PF00069	0.342
MOD_PKA_2	31	37	PF00069	0.379
MOD_PKA_2	450	456	PF00069	0.404
MOD_PKA_2	506	512	PF00069	0.473
MOD_PKA_2	526	532	PF00069	0.238
MOD_PKA_2	551	557	PF00069	0.632
MOD_PKB_1	166	174	PF00069	0.262
MOD_Plk_1	221	227	PF00069	0.210
MOD_Plk_1	329	335	PF00069	0.425
MOD_Plk_1	577	583	PF00069	0.477
MOD_Plk_4	316	322	PF00069	0.392
MOD_Plk_4	402	408	PF00069	0.326
MOD_Plk_4	537	543	PF00069	0.372
MOD_Plk_4	580	586	PF00069	0.546
MOD_ProDKin_1	119	125	PF00069	0.432
MOD_ProDKin_1	224	230	PF00069	0.391
MOD_ProDKin_1	241	247	PF00069	0.217
MOD_ProDKin_1	419	425	PF00069	0.357
MOD_ProDKin_1	555	561	PF00069	0.724
MOD_ProDKin_1	562	568	PF00069	0.635
MOD_ProDKin_1	91	97	PF00069	0.328
TRG_DiLeu_BaEn_3	280	286	PF01217	0.395
TRG_DiLeu_BaLyEn_6	235	240	PF01217	0.301
TRG_ENDOCYTIC_2	100	103	PF00928	0.378
TRG_ENDOCYTIC_2	413	416	PF00928	0.396
TRG_ENDOCYTIC_2	70	73	PF00928	0.301
TRG_ER_diArg_1	167	170	PF00400	0.374
TRG_ER_diArg_1	298	301	PF00400	0.355
TRG_ER_diArg_1	455	457	PF00400	0.418
TRG_ER_diArg_1	534	536	PF00400	0.280
TRG_Pf-PMV_PEXEL_1	106	110	PF00026	0.313
TRG_Pf-PMV_PEXEL_1	457	462	PF00026	0.428
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.339

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P983	Leptomonas seymouri	51%	100%
A0A3S7X5H4	Leishmania donovani	68%	70%
A4I7W7	Leishmania infantum	68%	70%
E9B2S7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	70%
Q4Q5D0	Leishmania major	70%	100%
V5AZH5	Trypanosoma cruzi	38%	100%