rRNA-processing protein FYV7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

rRNA processing, putative

Species:

Leishmania braziliensis

UniProt:

A4HKD6_LEIBR

TriTrypDb:

LbrM.32.1650 , LBRM2903_320022600

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKD6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKD6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	101	103	PF00675	0.377
CLV_NRD_NRD_1	130	132	PF00675	0.316
CLV_NRD_NRD_1	157	159	PF00675	0.304
CLV_NRD_NRD_1	34	36	PF00675	0.494
CLV_NRD_NRD_1	47	49	PF00675	0.323
CLV_NRD_NRD_1	67	69	PF00675	0.150
CLV_NRD_NRD_1	7	9	PF00675	0.530
CLV_NRD_NRD_1	95	97	PF00675	0.284
CLV_PCSK_KEX2_1	101	103	PF00082	0.332
CLV_PCSK_KEX2_1	132	134	PF00082	0.319
CLV_PCSK_KEX2_1	151	153	PF00082	0.246
CLV_PCSK_KEX2_1	167	169	PF00082	0.381
CLV_PCSK_KEX2_1	34	36	PF00082	0.494
CLV_PCSK_KEX2_1	59	61	PF00082	0.357
CLV_PCSK_KEX2_1	7	9	PF00082	0.523
CLV_PCSK_KEX2_1	95	97	PF00082	0.286
CLV_PCSK_PC1ET2_1	101	103	PF00082	0.301
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.269
CLV_PCSK_PC1ET2_1	151	153	PF00082	0.339
CLV_PCSK_PC1ET2_1	167	169	PF00082	0.413
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.301
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.286
CLV_PCSK_PC7_1	147	153	PF00082	0.339
CLV_PCSK_SKI1_1	17	21	PF00082	0.577
CLV_PCSK_SKI1_1	69	73	PF00082	0.338
DOC_PP1_SILK_1	76	81	PF00149	0.203
DOC_USP7_MATH_1	157	161	PF00917	0.413
DOC_USP7_MATH_1	174	178	PF00917	0.327
DOC_USP7_UBL2_3	167	171	PF12436	0.413
DOC_USP7_UBL2_3	93	97	PF12436	0.300
LIG_14-3-3_CanoR_1	102	109	PF00244	0.301
LIG_14-3-3_CanoR_1	161	165	PF00244	0.203
LIG_14-3-3_CanoR_1	26	30	PF00244	0.507
LIG_14-3-3_CanoR_1	66	75	PF00244	0.203
LIG_BIR_II_1	1	5	PF00653	0.682
LIG_FHA_1	70	76	PF00498	0.203
LIG_FHA_2	106	112	PF00498	0.276
LIG_FHA_2	26	32	PF00498	0.539
LIG_FHA_2	87	93	PF00498	0.296
LIG_LIR_Nem_3	45	50	PF02991	0.298
LIG_REV1ctd_RIR_1	18	27	PF16727	0.554
LIG_SH2_CRK	120	124	PF00017	0.362
LIG_SH2_CRK	47	51	PF00017	0.301
LIG_SH2_NCK_1	120	124	PF00017	0.433
LIG_SH2_STAP1	84	88	PF00017	0.301
LIG_TRAF2_1	71	74	PF00917	0.203
LIG_UBA3_1	183	189	PF00899	0.301
MOD_CK1_1	105	111	PF00069	0.310
MOD_CK1_1	160	166	PF00069	0.263
MOD_CK2_1	121	127	PF00069	0.337
MOD_CK2_1	175	181	PF00069	0.410
MOD_CK2_1	25	31	PF00069	0.505
MOD_CK2_1	67	73	PF00069	0.372
MOD_CK2_1	86	92	PF00069	0.218
MOD_Cter_Amidation	32	35	PF01082	0.533
MOD_GlcNHglycan	104	107	PF01048	0.331
MOD_GlcNHglycan	123	126	PF01048	0.358
MOD_GlcNHglycan	69	72	PF01048	0.311
MOD_GSK3_1	175	182	PF00069	0.415
MOD_GSK3_1	69	76	PF00069	0.283
MOD_NEK2_1	104	109	PF00069	0.373
MOD_PKA_1	102	108	PF00069	0.301
MOD_PKA_2	157	163	PF00069	0.468
MOD_PKA_2	25	31	PF00069	0.501
MOD_PKA_2	67	73	PF00069	0.203
MOD_Plk_1	73	79	PF00069	0.305
MOD_Plk_1	84	90	PF00069	0.271
MOD_Plk_4	160	166	PF00069	0.246
MOD_Plk_4	179	185	PF00069	0.354
MOD_Plk_4	25	31	PF00069	0.473
MOD_Plk_4	74	80	PF00069	0.244
MOD_SUMO_for_1	13	16	PF00179	0.483
TRG_DiLeu_BaEn_3	73	79	PF01217	0.203
TRG_ENDOCYTIC_2	120	123	PF00928	0.384
TRG_ENDOCYTIC_2	47	50	PF00928	0.314
TRG_ER_diArg_1	41	44	PF00400	0.283
TRG_NLS_Bipartite_1	115	135	PF00514	0.203
TRG_NLS_Bipartite_1	151	171	PF00514	0.370
TRG_NLS_MonoCore_2	93	98	PF00514	0.301
TRG_NLS_MonoExtC_3	130	135	PF00514	0.306
TRG_NLS_MonoExtC_3	166	171	PF00514	0.413
TRG_NLS_MonoExtN_4	93	99	PF00514	0.301
TRG_Pf-PMV_PEXEL_1	48	53	PF00026	0.314

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMW6	Leptomonas seymouri	78%	100%
A0A0S4J953	Bodo saltans	47%	84%
A0A1X0NUH7	Trypanosomatidae	54%	96%
A0A3R7KF30	Trypanosoma rangeli	52%	96%
A0A3S7X5G7	Leishmania donovani	84%	100%
A4I807	Leishmania infantum	85%	100%
D0AA30	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	94%
E9B2S4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q5D3	Leishmania major	85%	100%