Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HKD1_LEIBR

TriTrypDb:

LbrM.32.1600 , LBRM2903_320022100

Length:

147

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HKD1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HKD1

PDB structure(s): 7aih_BC , 7ane_BC

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	51	53	PF00675	0.425
CLV_PCSK_KEX2_1	51	53	PF00082	0.399
CLV_PCSK_KEX2_1	7	9	PF00082	0.383
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.431
CLV_PCSK_PC7_1	47	53	PF00082	0.398
CLV_Separin_Metazoa	44	48	PF03568	0.447
DEG_APCC_KENBOX_2	62	66	PF00400	0.328
DEG_Nend_UBRbox_3	1	3	PF02207	0.398
DOC_MAPK_gen_1	33	40	PF00069	0.515
DOC_MAPK_gen_1	51	58	PF00069	0.415

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I494	Leptomonas seymouri	83%	100%
A0A0S4J787	Bodo saltans	62%	100%
A0A1X0NUE5	Trypanosomatidae	76%	100%
A0A3Q8IGY2	Leishmania donovani	90%	100%
A0A3S5IR91	Trypanosoma rangeli	73%	100%
A4I7W1	Leishmania infantum	89%	100%
D0AA24	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
E9B2R9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4Q5D8	Leishmania major	88%	100%

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