Putative mitochondrial carrier protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial carrier protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HK93_LEIBR

TriTrypDb:

LbrM.32.1210 , LBRM2903_320017900

Length:

365

Annotations

LeishMANIAdb annotations

Homologous to eukaryotic mitochondrial carriers responsible for FAD and/or folate uptake. In some organisms, homologs also transport thiamine.. Localization: Mitochondrial (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 23
NetGPI	no	yes: 0, no: 23

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	24
GO:0110165	cellular anatomical entity	1	24
GO:0005739	mitochondrion	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2

Expansion

Sequence features

A4HK93

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HK93

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	24
GO:0006862	nucleotide transport	6	21
GO:0009987	cellular process	1	24
GO:0015748	organophosphate ester transport	5	21
GO:0015931	nucleobase-containing compound transport	5	21
GO:0051179	localization	1	24
GO:0051234	establishment of localization	2	24
GO:0055085	transmembrane transport	2	24
GO:0071702	organic substance transport	4	23
GO:0071705	nitrogen compound transport	4	23
GO:0006811	monoatomic ion transport	4	2
GO:0006820	monoatomic anion transport	5	2
GO:0006835	dicarboxylic acid transport	7	2
GO:0015711	organic anion transport	5	2
GO:0015849	organic acid transport	5	2
GO:0015884	folic acid transport	5	2
GO:0034220	monoatomic ion transmembrane transport	3	2
GO:0035461	vitamin transmembrane transport	3	2
GO:0042886	amide transport	5	2
GO:0046942	carboxylic acid transport	6	2
GO:0051180	vitamin transport	4	2
GO:0072337	modified amino acid transport	5	2
GO:0098656	monoatomic anion transmembrane transport	4	2
GO:0098838	folate transmembrane transport	4	2
GO:1903825	organic acid transmembrane transport	3	2
GO:1904947	folate import into mitochondrion	4	2
GO:1905039	carboxylic acid transmembrane transport	4	2
GO:1990542	mitochondrial transmembrane transport	3	2

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	2
GO:0005342	organic acid transmembrane transporter activity	3	2
GO:0008509	monoatomic anion transmembrane transporter activity	4	2
GO:0008514	organic anion transmembrane transporter activity	5	2
GO:0008517	folic acid transmembrane transporter activity	4	2
GO:0015075	monoatomic ion transmembrane transporter activity	3	2
GO:0015215	nucleotide transmembrane transporter activity	4	2
GO:0015230	FAD transmembrane transporter activity	5	2
GO:0015605	organophosphate ester transmembrane transporter activity	3	2
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3	2
GO:0022857	transmembrane transporter activity	2	2
GO:0042887	amide transmembrane transporter activity	3	2
GO:0046943	carboxylic acid transmembrane transporter activity	4	2
GO:0072349	modified amino acid transmembrane transporter activity	3	2
GO:0090482	vitamin transmembrane transporter activity	3	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	360	362	PF00675	0.609
CLV_PCSK_KEX2_1	252	254	PF00082	0.523
CLV_PCSK_KEX2_1	360	362	PF00082	0.572
CLV_PCSK_PC1ET2_1	252	254	PF00082	0.536
CLV_PCSK_SKI1_1	133	137	PF00082	0.268
CLV_PCSK_SKI1_1	253	257	PF00082	0.511
CLV_PCSK_SKI1_1	343	347	PF00082	0.356
DEG_Nend_UBRbox_2	1	3	PF02207	0.389
DEG_SPOP_SBC_1	177	181	PF00917	0.163
DEG_SPOP_SBC_1	202	206	PF00917	0.351
DEG_SPOP_SBC_1	314	318	PF00917	0.351
DOC_CYCLIN_yCln2_LP_2	287	293	PF00134	0.338
DOC_MAPK_MEF2A_6	229	237	PF00069	0.496
DOC_PP2B_LxvP_1	243	246	PF13499	0.330
DOC_PP2B_PxIxI_1	41	47	PF00149	0.367
DOC_USP7_MATH_1	202	206	PF00917	0.467
DOC_WW_Pin1_4	30	35	PF00397	0.470
LIG_14-3-3_CanoR_1	114	120	PF00244	0.549
LIG_14-3-3_CanoR_1	172	178	PF00244	0.256
LIG_14-3-3_CanoR_1	216	220	PF00244	0.466
LIG_14-3-3_CanoR_1	229	234	PF00244	0.438
LIG_14-3-3_CanoR_1	3	9	PF00244	0.568
LIG_14-3-3_CanoR_1	302	306	PF00244	0.520
LIG_BIR_III_4	52	56	PF00653	0.334
LIG_FHA_1	14	20	PF00498	0.350
LIG_FHA_1	165	171	PF00498	0.428
LIG_FHA_1	185	191	PF00498	0.362
LIG_FHA_1	219	225	PF00498	0.467
LIG_FHA_1	31	37	PF00498	0.353
LIG_FHA_1	315	321	PF00498	0.551
LIG_FHA_1	352	358	PF00498	0.256
LIG_FHA_1	41	47	PF00498	0.481
LIG_FHA_1	54	60	PF00498	0.468
LIG_FHA_2	5	11	PF00498	0.352
LIG_HP1_1	290	294	PF01393	0.428
LIG_Integrin_isoDGR_2	112	114	PF01839	0.244
LIG_LIR_Gen_1	247	256	PF02991	0.365
LIG_LIR_Gen_1	280	291	PF02991	0.395
LIG_LIR_Nem_3	164	169	PF02991	0.397
LIG_LIR_Nem_3	205	211	PF02991	0.434
LIG_LIR_Nem_3	226	231	PF02991	0.467
LIG_LIR_Nem_3	247	251	PF02991	0.298
LIG_LIR_Nem_3	280	286	PF02991	0.395
LIG_LIR_Nem_3	307	313	PF02991	0.438
LIG_LIR_Nem_3	87	93	PF02991	0.312
LIG_MYND_1	34	38	PF01753	0.350
LIG_PCNA_APIM_2	251	257	PF02747	0.230
LIG_SH2_CRK	153	157	PF00017	0.348
LIG_SH2_CRK	248	252	PF00017	0.377
LIG_SH2_CRK	310	314	PF00017	0.480
LIG_SH2_STAP1	166	170	PF00017	0.356
LIG_SH2_STAP1	351	355	PF00017	0.254
LIG_SH2_STAT3	217	220	PF00017	0.477
LIG_SH2_STAT5	155	158	PF00017	0.316
LIG_SH2_STAT5	166	169	PF00017	0.367
LIG_SH2_STAT5	217	220	PF00017	0.386
LIG_SH2_STAT5	349	352	PF00017	0.315
LIG_SH3_3	183	189	PF00018	0.325
LIG_SH3_3	3	9	PF00018	0.376
LIG_SH3_3	86	92	PF00018	0.243
LIG_SUMO_SIM_anti_2	121	127	PF11976	0.440
LIG_SUMO_SIM_anti_2	173	181	PF11976	0.293
LIG_SUMO_SIM_anti_2	354	359	PF11976	0.357
LIG_SUMO_SIM_par_1	283	288	PF11976	0.344
LIG_SUMO_SIM_par_1	42	47	PF11976	0.580
LIG_SUMO_SIM_par_1	70	76	PF11976	0.244
LIG_WRC_WIRS_1	208	213	PF05994	0.471
MOD_CK1_1	118	124	PF00069	0.400
MOD_CK1_1	173	179	PF00069	0.322
MOD_CK1_1	180	186	PF00069	0.324
MOD_CK1_1	277	283	PF00069	0.337
MOD_CK1_1	29	35	PF00069	0.549
MOD_CK1_1	4	10	PF00069	0.351
MOD_CK1_1	83	89	PF00069	0.350
MOD_CK2_1	4	10	PF00069	0.351
MOD_GlcNHglycan	13	16	PF01048	0.661
MOD_GlcNHglycan	172	175	PF01048	0.466
MOD_GlcNHglycan	276	279	PF01048	0.338
MOD_GlcNHglycan	28	31	PF01048	0.595
MOD_GlcNHglycan	63	66	PF01048	0.663
MOD_GlcNHglycan	82	85	PF01048	0.292
MOD_GSK3_1	114	121	PF00069	0.471
MOD_GSK3_1	161	168	PF00069	0.356
MOD_GSK3_1	173	180	PF00069	0.314
MOD_GSK3_1	203	210	PF00069	0.489
MOD_GSK3_1	215	222	PF00069	0.471
MOD_GSK3_1	26	33	PF00069	0.501
MOD_GSK3_1	309	316	PF00069	0.466
MOD_GSK3_1	337	344	PF00069	0.308
MOD_GSK3_1	76	83	PF00069	0.330
MOD_N-GLC_1	119	124	PF02516	0.305
MOD_N-GLC_1	161	166	PF02516	0.584
MOD_N-GLC_1	202	207	PF02516	0.341
MOD_NEK2_1	1	6	PF00069	0.437
MOD_NEK2_1	119	124	PF00069	0.477
MOD_NEK2_1	178	183	PF00069	0.315
MOD_NEK2_1	192	197	PF00069	0.458
MOD_NEK2_1	215	220	PF00069	0.447
MOD_NEK2_1	285	290	PF00069	0.327
MOD_NEK2_1	337	342	PF00069	0.328
MOD_NEK2_2	131	136	PF00069	0.475
MOD_NEK2_2	92	97	PF00069	0.457
MOD_PIKK_1	320	326	PF00454	0.541
MOD_PIKK_1	76	82	PF00454	0.318
MOD_PKA_2	215	221	PF00069	0.498
MOD_PKA_2	301	307	PF00069	0.546
MOD_Plk_1	1	7	PF00069	0.361
MOD_Plk_1	119	125	PF00069	0.351
MOD_Plk_1	164	170	PF00069	0.371
MOD_Plk_1	351	357	PF00069	0.315
MOD_Plk_2-3	47	53	PF00069	0.502
MOD_Plk_4	143	149	PF00069	0.350
MOD_Plk_4	165	171	PF00069	0.385
MOD_Plk_4	173	179	PF00069	0.274
MOD_Plk_4	207	213	PF00069	0.422
MOD_Plk_4	353	359	PF00069	0.281
MOD_ProDKin_1	30	36	PF00069	0.472
TRG_ENDOCYTIC_2	116	119	PF00928	0.459
TRG_ENDOCYTIC_2	153	156	PF00928	0.326
TRG_ENDOCYTIC_2	157	160	PF00928	0.212
TRG_ENDOCYTIC_2	208	211	PF00928	0.430
TRG_ENDOCYTIC_2	248	251	PF00928	0.293
TRG_ENDOCYTIC_2	310	313	PF00928	0.454
TRG_ENDOCYTIC_2	330	333	PF00928	0.323
TRG_ER_diArg_1	256	259	PF00400	0.348
TRG_ER_diArg_1	360	362	PF00400	0.387
TRG_Pf-PMV_PEXEL_1	229	234	PF00026	0.280
TRG_Pf-PMV_PEXEL_1	311	315	PF00026	0.151

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4V4	Leptomonas seymouri	24%	100%
A0A0N0P7X0	Leptomonas seymouri	23%	100%
A0A0N0P7Y4	Leptomonas seymouri	22%	100%
A0A0N0P8W6	Leptomonas seymouri	22%	100%
A0A0N1I6I9	Leptomonas seymouri	25%	100%
A0A0N1IK46	Leptomonas seymouri	22%	100%
A0A0N1IMP5	Leptomonas seymouri	41%	100%
A0A0N1PFJ3	Leptomonas seymouri	77%	100%
A0A0S4IMF4	Bodo saltans	23%	100%
A0A0S4J045	Bodo saltans	24%	100%
A0A0S4J9F4	Bodo saltans	39%	100%
A0A0S4JHC1	Bodo saltans	25%	100%
A0A0S4JM95	Bodo saltans	22%	100%
A0A0S4KJX8	Bodo saltans	28%	100%
A0A0U2IR85	Ustilago maydis	21%	100%
A0A1D6N272	Zea mays	25%	100%
A0A1X0NJD2	Trypanosomatidae	24%	100%
A0A1X0NTK9	Trypanosomatidae	22%	100%
A0A1X0NUM8	Trypanosomatidae	54%	100%
A0A1X0NUU7	Trypanosomatidae	45%	100%
A0A1X0P4Q9	Trypanosomatidae	24%	100%
A0A1X0P6S2	Trypanosomatidae	25%	100%
A0A1X0P952	Trypanosomatidae	20%	100%
A0A3Q8I9Y9	Leishmania donovani	21%	100%
A0A3Q8IFU6	Leishmania donovani	40%	100%
A0A3Q8IKX9	Leishmania donovani	87%	100%
A0A3R7KLL6	Trypanosoma rangeli	25%	100%
A0A3R7LCB2	Trypanosoma rangeli	46%	100%
A0A3R7P246	Trypanosoma rangeli	48%	100%
A0A3R7RT89	Trypanosoma rangeli	24%	100%
A0A3S5H7M7	Leishmania donovani	23%	100%
A0A3S5H800	Leishmania donovani	25%	100%
A0A3S7WTS6	Leishmania donovani	21%	100%
A0A3S7WYS1	Leishmania donovani	24%	100%
A0A3S7X2U2	Leishmania donovani	24%	100%
A0A422N763	Trypanosoma rangeli	28%	100%
A0A422NF39	Trypanosoma rangeli	25%	100%
A0A422NSB9	Trypanosoma rangeli	21%	100%
A0JN87	Bos taurus	23%	100%
A0PC02	Ochotona dauurica	22%	100%
A1DI57	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	23%	100%
A2ADF7	Mus musculus	23%	100%
A2ASZ8	Mus musculus	24%	78%
A2CEQ0	Danio rerio	23%	78%
A2R5A0	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	24%	100%
A3LVX1	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	22%	100%
A4H7Y2	Leishmania braziliensis	21%	100%
A4H8E6	Leishmania braziliensis	21%	100%
A4HDW8	Leishmania braziliensis	23%	99%
A4HHT5	Leishmania braziliensis	24%	100%
A4HI60	Leishmania braziliensis	24%	100%
A4HK94	Leishmania braziliensis	41%	100%
A4HN00	Leishmania braziliensis	23%	100%
A4HWA9	Leishmania infantum	21%	100%
A4HWR9	Leishmania infantum	22%	100%
A4I163	Leishmania infantum	24%	100%
A4I4Z5	Leishmania infantum	24%	100%
A4I5D6	Leishmania infantum	23%	100%
A4I7S8	Leishmania infantum	87%	100%
A4I7S9	Leishmania infantum	41%	100%
A4IBM3	Leishmania infantum	24%	100%
A4RF23	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	25%	100%
A5DIS9	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	22%	100%
A5DX39	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	23%	100%
A5PJZ1	Bos taurus	23%	77%
A6QR09	Bos taurus	23%	100%
A6RF73	Ajellomyces capsulatus (strain NAm1 / WU24)	24%	100%
A6SL61	Botryotinia fuckeliana (strain B05.10)	24%	100%
A6ZV78	Saccharomyces cerevisiae (strain YJM789)	22%	100%
A7ER02	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	24%	100%
B0G143	Dictyostelium discoideum	22%	100%
B0G159	Dictyostelium discoideum	20%	77%
B2MVX9	Ovis aries	23%	100%
B4FIJ0	Zea mays	25%	100%
B6ZJZ9	Glycine max	23%	100%
B8ZHC9	Rattus norvegicus	23%	100%
C9ZKK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
C9ZNU5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
C9ZW54	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
C9ZYS8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	100%
C9ZZ11	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A5E9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0A9Y8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
D0A9Z0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
E8NHL5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AFF7	Leishmania major	25%	100%
E9ALE6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AQ09	Leishmania mexicana (strain MHOM/GT/2001/U1103)	20%	100%
E9AQH7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AX97	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9B0N4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9B2N6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
E9B2N7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
F1R4U0	Danio rerio	20%	100%
F1RFX9	Sus scrofa	21%	100%
F4HT41	Arabidopsis thaliana	23%	100%
O04200	Arabidopsis thaliana	22%	100%
O04619	Arabidopsis thaliana	23%	100%
O13660	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O18757	Oryctolagus cuniculus	23%	77%
O22261	Arabidopsis thaliana	26%	100%
O43808	Homo sapiens	24%	100%
O65023	Arabidopsis thaliana	23%	96%
O70579	Mus musculus	23%	100%
O81845	Arabidopsis thaliana	24%	100%
O94502	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	21%	86%
O95258	Homo sapiens	25%	100%
O95847	Homo sapiens	26%	100%
O97562	Sus scrofa	21%	100%
P04575	Mesocricetus auratus	20%	100%
P04633	Rattus norvegicus	22%	100%
P0CAT2	Danio rerio	24%	100%
P10566	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	100%
P14271	Oryctolagus cuniculus	20%	100%
P22292	Bos taurus	22%	100%
P29518	Zea mays	23%	84%
P32089	Rattus norvegicus	22%	100%
P32332	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	100%
P33303	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P38127	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	97%
P38152	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P39953	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P40464	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P40556	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	98%
P53007	Homo sapiens	22%	100%
P53257	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	100%
P55851	Homo sapiens	23%	100%
P56500	Rattus norvegicus	23%	100%
P70406	Mus musculus	23%	100%
P79110	Bos taurus	22%	100%
P90992	Caenorhabditis elegans	22%	100%
Q02978	Homo sapiens	21%	100%
Q03829	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	99%
Q06497	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	100%
Q08DK7	Bos taurus	23%	100%
Q0CEN9	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	25%	100%
Q0UUH1	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	24%	100%
Q0V7M4	Bos taurus	24%	78%
Q0VCH6	Bos taurus	21%	100%
Q10248	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
Q12251	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q12375	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	100%
Q17QI7	Bos taurus	21%	100%
Q19529	Caenorhabditis elegans	23%	69%
Q1E7P0	Coccidioides immitis (strain RS)	24%	100%
Q1LZB3	Bos taurus	27%	100%
Q23125	Caenorhabditis elegans	23%	100%
Q29RM1	Bos taurus	24%	100%
Q2UCW8	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	24%	100%
Q3SZI5	Bos taurus	22%	100%
Q3TZX3	Mus musculus	26%	100%
Q499U1	Rattus norvegicus	24%	100%
Q4Q5H0	Leishmania major	40%	100%
Q4Q5H1	Leishmania major	85%	100%
Q4Q7J8	Leishmania major	23%	100%
Q4QA75	Leishmania major	24%	99%
Q4QF00	Leishmania major	21%	100%
Q4QFH2	Leishmania major	20%	100%
Q4V9P0	Danio rerio	24%	100%
Q4X022	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	23%	100%
Q54BM3	Dictyostelium discoideum	24%	100%
Q54DU1	Dictyostelium discoideum	21%	100%
Q54EV4	Dictyostelium discoideum	23%	100%
Q54FE6	Dictyostelium discoideum	22%	100%
Q54FU9	Dictyostelium discoideum	23%	100%
Q54MZ4	Dictyostelium discoideum	22%	84%
Q54PY7	Dictyostelium discoideum	23%	100%
Q54QN2	Dictyostelium discoideum	26%	100%
Q54W11	Dictyostelium discoideum	22%	100%
Q55BF4	Dictyostelium discoideum	23%	100%
Q55DY8	Dictyostelium discoideum	22%	100%
Q55E85	Dictyostelium discoideum	21%	100%
Q55GE2	Dictyostelium discoideum	24%	100%
Q5AVW1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	100%
Q5EAC0	Bos taurus	23%	100%
Q5HZE0	Rattus norvegicus	23%	100%
Q5IS35	Macaca fascicularis	23%	100%
Q5NVC1	Pongo abelii	22%	100%
Q5PQM9	Rattus norvegicus	27%	100%
Q5R5A8	Pongo abelii	24%	100%
Q5RFB7	Pongo abelii	22%	100%
Q5SVS4	Homo sapiens	27%	100%
Q5U680	Mus musculus	21%	100%
Q5XGI1	Xenopus tropicalis	26%	100%
Q5XH95	Xenopus tropicalis	25%	71%
Q5XHA0	Xenopus tropicalis	23%	77%
Q5ZKP7	Gallus gallus	25%	100%
Q620A6	Caenorhabditis briggsae	23%	100%
Q628Z2	Caenorhabditis briggsae	23%	69%
Q66H23	Rattus norvegicus	23%	100%
Q66L49	Danio rerio	21%	77%
Q6BPW0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	22%	100%
Q6CQR3	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	100%
Q6DG32	Danio rerio	24%	100%
Q6DHC3	Danio rerio	25%	100%
Q6GQ22	Xenopus laevis	26%	100%
Q6GQS1	Mus musculus	24%	78%
Q6IZB5	Cricetulus griseus	25%	100%
Q6KCM7	Homo sapiens	24%	78%
Q6NUK1	Homo sapiens	23%	77%
Q6NYZ6	Danio rerio	26%	78%
Q6P036	Danio rerio	24%	100%
Q6PGY3	Danio rerio	21%	100%
Q6PIV7	Homo sapiens	22%	100%
Q76P23	Dictyostelium discoideum	22%	100%
Q76PC3	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
Q7K566	Drosophila melanogaster	24%	100%
Q7S2H8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	100%
Q7SXW0	Danio rerio	23%	100%
Q7T0U6	Xenopus laevis	23%	77%
Q7XA87	Arabidopsis thaliana	27%	100%
Q7ZY36	Xenopus laevis	22%	77%
Q7ZYD5	Xenopus laevis	24%	71%
Q84UC7	Arabidopsis thaliana	25%	100%
Q86AV5	Dictyostelium discoideum	22%	100%
Q86HN8	Dictyostelium discoideum	23%	84%
Q86I81	Dictyostelium discoideum	22%	100%
Q8BL03	Mus musculus	22%	100%
Q8BMD8	Mus musculus	22%	77%
Q8BMG8	Mus musculus	25%	100%
Q8BVN7	Mus musculus	23%	100%
Q8BZ09	Mus musculus	23%	100%
Q8HXE3	Macaca fascicularis	27%	100%
Q8JZU2	Mus musculus	22%	100%
Q8K3P6	Rattus norvegicus	24%	78%
Q8N5S1	Homo sapiens	22%	99%
Q8N8R3	Homo sapiens	22%	100%
Q8R0Z5	Mus musculus	24%	100%
Q8RWA5	Arabidopsis thaliana	22%	100%
Q8RXZ9	Arabidopsis thaliana	25%	100%
Q8TBP6	Homo sapiens	20%	100%
Q8TFH2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
Q8VZS0	Arabidopsis thaliana	21%	100%
Q91XD8	Mus musculus	24%	100%
Q920G8	Mus musculus	24%	100%
Q922G0	Mus musculus	23%	100%
Q93XM7	Arabidopsis thaliana	23%	100%
Q95J75	Macaca fascicularis	25%	100%
Q96A46	Homo sapiens	24%	100%
Q96CQ1	Homo sapiens	24%	100%
Q96DW6	Homo sapiens	22%	100%
Q99297	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	100%
Q9BQT8	Homo sapiens	22%	100%
Q9BSK2	Homo sapiens	26%	100%
Q9BV35	Homo sapiens	24%	78%
Q9CA93	Arabidopsis thaliana	24%	100%
Q9CR58	Mus musculus	27%	100%
Q9CR62	Mus musculus	21%	100%
Q9D8K8	Mus musculus	21%	100%
Q9DAM5	Mus musculus	22%	100%
Q9ER18	Phodopus sungorus	20%	100%
Q9FHX2	Arabidopsis thaliana	22%	89%
Q9FI43	Arabidopsis thaliana	24%	75%
Q9FI73	Arabidopsis thaliana	24%	100%
Q9FLS8	Arabidopsis thaliana	25%	76%
Q9GMZ1	Canis lupus familiaris	22%	100%
Q9H2D1	Homo sapiens	25%	100%
Q9HC21	Homo sapiens	22%	100%
Q9LJX5	Arabidopsis thaliana	21%	100%
Q9LY28	Arabidopsis thaliana	23%	76%
Q9M024	Arabidopsis thaliana	22%	88%
Q9MA90	Arabidopsis thaliana	22%	100%
Q9N2J1	Canis lupus familiaris	23%	100%
Q9NYZ2	Homo sapiens	22%	100%
Q9P6L7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
Q9SJY5	Arabidopsis thaliana	22%	100%
Q9SUV1	Arabidopsis thaliana	23%	93%
Q9UTN1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
Q9VAY3	Drosophila melanogaster	22%	96%
Q9VM51	Drosophila melanogaster	22%	100%
Q9VMK1	Drosophila melanogaster	24%	100%
Q9VQ37	Drosophila melanogaster	26%	100%
Q9W720	Danio rerio	21%	100%
Q9W725	Cyprinus carpio	20%	100%
Q9XI74	Arabidopsis thaliana	25%	100%
Q9Z2B2	Mus musculus	25%	100%
Q9ZWG1	Arabidopsis thaliana	25%	100%
V5B150	Trypanosoma cruzi	46%	100%
V5BGM6	Trypanosoma cruzi	55%	100%
V5BSW1	Trypanosoma cruzi	23%	100%
V5BTA6	Trypanosoma cruzi	21%	100%
V5BTE8	Trypanosoma cruzi	26%	100%
V5BVW0	Trypanosoma cruzi	23%	100%
V5C243	Trypanosoma cruzi	25%	100%