LeishMANIAdb
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Putative serine/threonine protein kinase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative serine/threonine protein kinase
Gene product:
Repressor of differentiation kinase 1, putative
Species:
Leishmania braziliensis
UniProt:
A4HK62_LEIBR
TriTrypDb:
LbrM.32.0900 , LBRM2903_320014200 *
Length:
1353

Annotations

LeishMANIAdb annotations

This unusual receptor kinase contains at least 2TM segments (possibly even 4TM), an N-terminal sensor domain and 2 tandem protein kinase domains!. This kinase family is a result of expansive receptor evolution within kinetoplastids. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

A4HK62
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 7
GO:0006793 phosphorus metabolic process 3 7
GO:0006796 phosphate-containing compound metabolic process 4 7
GO:0006807 nitrogen compound metabolic process 2 7
GO:0008152 metabolic process 1 7
GO:0009987 cellular process 1 7
GO:0016310 phosphorylation 5 7
GO:0019538 protein metabolic process 3 7
GO:0036211 protein modification process 4 7
GO:0043170 macromolecule metabolic process 3 7
GO:0043412 macromolecule modification 4 7
GO:0044237 cellular metabolic process 2 7
GO:0044238 primary metabolic process 2 7
GO:0071704 organic substance metabolic process 2 7
GO:1901564 organonitrogen compound metabolic process 3 7
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 7
GO:0003824 catalytic activity 1 7
GO:0004672 protein kinase activity 3 7
GO:0004674 protein serine/threonine kinase activity 4 6
GO:0005488 binding 1 7
GO:0005524 ATP binding 5 7
GO:0016301 kinase activity 4 7
GO:0016740 transferase activity 2 7
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 7
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 7
GO:0017076 purine nucleotide binding 4 7
GO:0030554 adenyl nucleotide binding 5 7
GO:0032553 ribonucleotide binding 3 7
GO:0032555 purine ribonucleotide binding 4 7
GO:0032559 adenyl ribonucleotide binding 5 7
GO:0035639 purine ribonucleoside triphosphate binding 4 7
GO:0036094 small molecule binding 2 7
GO:0043167 ion binding 2 7
GO:0043168 anion binding 3 7
GO:0097159 organic cyclic compound binding 2 7
GO:0097367 carbohydrate derivative binding 2 7
GO:0140096 catalytic activity, acting on a protein 2 7
GO:1901265 nucleoside phosphate binding 3 7
GO:1901363 heterocyclic compound binding 2 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1172 1176 PF00656 0.526
CLV_C14_Caspase3-7 1291 1295 PF00656 0.561
CLV_C14_Caspase3-7 1319 1323 PF00656 0.526
CLV_C14_Caspase3-7 33 37 PF00656 0.669
CLV_C14_Caspase3-7 57 61 PF00656 0.546
CLV_C14_Caspase3-7 612 616 PF00656 0.400
CLV_C14_Caspase3-7 809 813 PF00656 0.580
CLV_NRD_NRD_1 1186 1188 PF00675 0.274
CLV_NRD_NRD_1 38 40 PF00675 0.395
CLV_NRD_NRD_1 619 621 PF00675 0.543
CLV_NRD_NRD_1 958 960 PF00675 0.444
CLV_PCSK_KEX2_1 1116 1118 PF00082 0.274
CLV_PCSK_KEX2_1 114 116 PF00082 0.308
CLV_PCSK_KEX2_1 1186 1188 PF00082 0.274
CLV_PCSK_KEX2_1 216 218 PF00082 0.361
CLV_PCSK_KEX2_1 38 40 PF00082 0.395
CLV_PCSK_KEX2_1 540 542 PF00082 0.479
CLV_PCSK_KEX2_1 619 621 PF00082 0.543
CLV_PCSK_KEX2_1 850 852 PF00082 0.340
CLV_PCSK_PC1ET2_1 1116 1118 PF00082 0.274
CLV_PCSK_PC1ET2_1 114 116 PF00082 0.308
CLV_PCSK_PC1ET2_1 216 218 PF00082 0.361
CLV_PCSK_PC1ET2_1 540 542 PF00082 0.479
CLV_PCSK_PC1ET2_1 850 852 PF00082 0.340
CLV_PCSK_PC7_1 1182 1188 PF00082 0.274
CLV_PCSK_SKI1_1 1123 1127 PF00082 0.274
CLV_PCSK_SKI1_1 1187 1191 PF00082 0.294
CLV_PCSK_SKI1_1 208 212 PF00082 0.234
CLV_PCSK_SKI1_1 381 385 PF00082 0.327
CLV_PCSK_SKI1_1 403 407 PF00082 0.308
CLV_PCSK_SKI1_1 537 541 PF00082 0.502
CLV_PCSK_SKI1_1 703 707 PF00082 0.575
CLV_PCSK_SKI1_1 742 746 PF00082 0.320
CLV_PCSK_SKI1_1 833 837 PF00082 0.370
CLV_PCSK_SKI1_1 984 988 PF00082 0.538
DEG_APCC_DBOX_1 114 122 PF00400 0.521
DEG_APCC_DBOX_1 1186 1194 PF00400 0.474
DEG_Nend_Nbox_1 1 3 PF02207 0.520
DEG_ODPH_VHL_1 601 613 PF01847 0.309
DEG_SCF_FBW7_1 965 970 PF00400 0.731
DEG_SPOP_SBC_1 679 683 PF00917 0.297
DEG_SPOP_SBC_1 764 768 PF00917 0.527
DEG_SPOP_SBC_1 907 911 PF00917 0.664
DOC_CDC14_PxL_1 1115 1123 PF14671 0.474
DOC_CYCLIN_yCln2_LP_2 940 946 PF00134 0.619
DOC_MAPK_gen_1 114 121 PF00069 0.520
DOC_MAPK_gen_1 1186 1192 PF00069 0.474
DOC_MAPK_gen_1 1243 1252 PF00069 0.488
DOC_MAPK_gen_1 460 469 PF00069 0.562
DOC_MAPK_gen_1 737 745 PF00069 0.514
DOC_MAPK_gen_1 850 857 PF00069 0.544
DOC_MAPK_MEF2A_6 12 19 PF00069 0.590
DOC_MAPK_MEF2A_6 1209 1217 PF00069 0.474
DOC_MAPK_MEF2A_6 510 518 PF00069 0.414
DOC_MAPK_NFAT4_5 12 20 PF00069 0.594
DOC_MAPK_RevD_3 1102 1117 PF00069 0.474
DOC_PP1_RVXF_1 206 213 PF00149 0.254
DOC_PP1_RVXF_1 717 724 PF00149 0.326
DOC_PP1_RVXF_1 740 746 PF00149 0.519
DOC_PP1_RVXF_1 753 759 PF00149 0.490
DOC_PP4_FxxP_1 357 360 PF00568 0.503
DOC_PP4_MxPP_1 935 938 PF00568 0.532
DOC_USP7_MATH_1 1093 1097 PF00917 0.474
DOC_USP7_MATH_1 1166 1170 PF00917 0.474
DOC_USP7_MATH_1 123 127 PF00917 0.627
DOC_USP7_MATH_1 1261 1265 PF00917 0.474
DOC_USP7_MATH_1 1329 1333 PF00917 0.480
DOC_USP7_MATH_1 71 75 PF00917 0.567
DOC_USP7_MATH_1 736 740 PF00917 0.557
DOC_USP7_MATH_1 775 779 PF00917 0.514
DOC_USP7_MATH_1 806 810 PF00917 0.589
DOC_USP7_MATH_1 901 905 PF00917 0.570
DOC_USP7_MATH_1 945 949 PF00917 0.549
DOC_USP7_UBL2_3 829 833 PF12436 0.511
DOC_WW_Pin1_4 1030 1035 PF00397 0.604
DOC_WW_Pin1_4 1043 1048 PF00397 0.566
DOC_WW_Pin1_4 1250 1255 PF00397 0.474
DOC_WW_Pin1_4 267 272 PF00397 0.589
DOC_WW_Pin1_4 918 923 PF00397 0.576
DOC_WW_Pin1_4 963 968 PF00397 0.695
DOC_WW_Pin1_4 972 977 PF00397 0.646
LIG_14-3-3_CanoR_1 12 18 PF00244 0.540
LIG_14-3-3_CanoR_1 179 185 PF00244 0.295
LIG_14-3-3_CanoR_1 208 213 PF00244 0.494
LIG_14-3-3_CanoR_1 217 223 PF00244 0.598
LIG_14-3-3_CanoR_1 462 467 PF00244 0.462
LIG_14-3-3_CanoR_1 482 489 PF00244 0.418
LIG_14-3-3_CanoR_1 959 969 PF00244 0.751
LIG_14-3-3_CanoR_1 984 992 PF00244 0.651
LIG_AP2alpha_2 805 807 PF02296 0.485
LIG_AP2alpha_2 916 918 PF02296 0.541
LIG_APCC_ABBA_1 294 299 PF00400 0.560
LIG_BIR_III_2 1294 1298 PF00653 0.481
LIG_BIR_III_4 1064 1068 PF00653 0.631
LIG_BRCT_BRCA1_1 1095 1099 PF00533 0.487
LIG_BRCT_BRCA1_1 1347 1351 PF00533 0.474
LIG_BRCT_BRCA1_1 351 355 PF00533 0.473
LIG_BRCT_BRCA1_1 680 684 PF00533 0.301
LIG_Clathr_ClatBox_1 1214 1218 PF01394 0.474
LIG_Clathr_ClatBox_1 836 840 PF01394 0.580
LIG_FHA_1 1061 1067 PF00498 0.506
LIG_FHA_1 1291 1297 PF00498 0.526
LIG_FHA_1 179 185 PF00498 0.332
LIG_FHA_1 188 194 PF00498 0.316
LIG_FHA_1 288 294 PF00498 0.487
LIG_FHA_1 339 345 PF00498 0.575
LIG_FHA_1 400 406 PF00498 0.597
LIG_FHA_1 436 442 PF00498 0.568
LIG_FHA_1 454 460 PF00498 0.522
LIG_FHA_1 462 468 PF00498 0.505
LIG_FHA_1 484 490 PF00498 0.450
LIG_FHA_1 509 515 PF00498 0.448
LIG_FHA_1 616 622 PF00498 0.333
LIG_FHA_1 671 677 PF00498 0.363
LIG_FHA_1 766 772 PF00498 0.519
LIG_FHA_1 864 870 PF00498 0.462
LIG_FHA_1 964 970 PF00498 0.692
LIG_FHA_1 973 979 PF00498 0.725
LIG_FHA_2 1040 1046 PF00498 0.728
LIG_FHA_2 1202 1208 PF00498 0.487
LIG_FHA_2 1340 1346 PF00498 0.503
LIG_FHA_2 218 224 PF00498 0.586
LIG_FHA_2 300 306 PF00498 0.552
LIG_FHA_2 797 803 PF00498 0.521
LIG_FHA_2 969 975 PF00498 0.683
LIG_GBD_Chelix_1 159 167 PF00786 0.227
LIG_Integrin_RGD_1 499 501 PF01839 0.283
LIG_IRF3_LxIS_1 1268 1274 PF10401 0.474
LIG_LIR_Apic_2 1248 1254 PF02991 0.503
LIG_LIR_Gen_1 1096 1106 PF02991 0.526
LIG_LIR_Gen_1 1154 1165 PF02991 0.474
LIG_LIR_Gen_1 1274 1283 PF02991 0.484
LIG_LIR_Gen_1 1348 1353 PF02991 0.494
LIG_LIR_Gen_1 149 158 PF02991 0.245
LIG_LIR_Gen_1 248 256 PF02991 0.475
LIG_LIR_Gen_1 263 272 PF02991 0.568
LIG_LIR_Gen_1 352 363 PF02991 0.498
LIG_LIR_Gen_1 578 587 PF02991 0.295
LIG_LIR_Gen_1 634 645 PF02991 0.426
LIG_LIR_Gen_1 805 814 PF02991 0.507
LIG_LIR_Gen_1 865 876 PF02991 0.523
LIG_LIR_LC3C_4 517 521 PF02991 0.383
LIG_LIR_Nem_3 1009 1015 PF02991 0.569
LIG_LIR_Nem_3 1096 1102 PF02991 0.474
LIG_LIR_Nem_3 1154 1160 PF02991 0.474
LIG_LIR_Nem_3 1175 1180 PF02991 0.526
LIG_LIR_Nem_3 1348 1352 PF02991 0.494
LIG_LIR_Nem_3 149 153 PF02991 0.245
LIG_LIR_Nem_3 248 254 PF02991 0.475
LIG_LIR_Nem_3 263 269 PF02991 0.564
LIG_LIR_Nem_3 351 357 PF02991 0.507
LIG_LIR_Nem_3 578 583 PF02991 0.293
LIG_LIR_Nem_3 634 640 PF02991 0.367
LIG_LIR_Nem_3 670 675 PF02991 0.380
LIG_LIR_Nem_3 682 688 PF02991 0.285
LIG_LIR_Nem_3 805 810 PF02991 0.492
LIG_LIR_Nem_3 865 871 PF02991 0.516
LIG_MLH1_MIPbox_1 351 355 PF16413 0.446
LIG_MLH1_MIPbox_1 681 685 PF16413 0.304
LIG_MYND_3 291 295 PF01753 0.563
LIG_NRBOX 234 240 PF00104 0.491
LIG_PDZ_Class_2 1348 1353 PF00595 0.474
LIG_Pex14_2 357 361 PF04695 0.506
LIG_Pex14_2 502 506 PF04695 0.497
LIG_Pex14_2 684 688 PF04695 0.331
LIG_Pex14_2 924 928 PF04695 0.522
LIG_PTB_Apo_2 58 65 PF02174 0.486
LIG_PTB_Phospho_1 58 64 PF10480 0.483
LIG_SH2_GRB2like 354 357 PF00017 0.505
LIG_SH2_NCK_1 261 265 PF00017 0.510
LIG_SH2_PTP2 1251 1254 PF00017 0.474
LIG_SH2_PTP2 868 871 PF00017 0.519
LIG_SH2_SRC 34 37 PF00017 0.668
LIG_SH2_SRC 675 678 PF00017 0.357
LIG_SH2_STAT5 1103 1106 PF00017 0.474
LIG_SH2_STAT5 1148 1151 PF00017 0.474
LIG_SH2_STAT5 1157 1160 PF00017 0.478
LIG_SH2_STAT5 1198 1201 PF00017 0.474
LIG_SH2_STAT5 1251 1254 PF00017 0.474
LIG_SH2_STAT5 170 173 PF00017 0.369
LIG_SH2_STAT5 183 186 PF00017 0.370
LIG_SH2_STAT5 2 5 PF00017 0.557
LIG_SH2_STAT5 251 254 PF00017 0.483
LIG_SH2_STAT5 261 264 PF00017 0.521
LIG_SH2_STAT5 266 269 PF00017 0.613
LIG_SH2_STAT5 312 315 PF00017 0.505
LIG_SH2_STAT5 354 357 PF00017 0.506
LIG_SH2_STAT5 369 372 PF00017 0.512
LIG_SH2_STAT5 429 432 PF00017 0.567
LIG_SH2_STAT5 569 572 PF00017 0.284
LIG_SH2_STAT5 672 675 PF00017 0.432
LIG_SH2_STAT5 868 871 PF00017 0.519
LIG_SH2_STAT5 876 879 PF00017 0.541
LIG_SH3_3 1007 1013 PF00018 0.671
LIG_SH3_3 104 110 PF00018 0.632
LIG_SH3_3 1312 1318 PF00018 0.474
LIG_SH3_3 300 306 PF00018 0.502
LIG_SH3_3 67 73 PF00018 0.508
LIG_SH3_3 722 728 PF00018 0.310
LIG_SH3_3 786 792 PF00018 0.503
LIG_SUMO_SIM_anti_2 1156 1163 PF11976 0.474
LIG_SUMO_SIM_anti_2 237 243 PF11976 0.488
LIG_SUMO_SIM_anti_2 299 305 PF11976 0.494
LIG_SUMO_SIM_anti_2 515 520 PF11976 0.318
LIG_SUMO_SIM_par_1 1313 1320 PF11976 0.472
LIG_SUMO_SIM_par_1 643 648 PF11976 0.309
LIG_SUMO_SIM_par_1 694 699 PF11976 0.291
LIG_SUMO_SIM_par_1 749 754 PF11976 0.479
LIG_TRAF2_1 132 135 PF00917 0.619
LIG_TRAF2_1 1342 1345 PF00917 0.526
LIG_TRAF2_1 221 224 PF00917 0.646
LIG_TRAF2_1 883 886 PF00917 0.526
LIG_TYR_ITIM 249 254 PF00017 0.424
LIG_UBA3_1 750 755 PF00899 0.485
LIG_WRC_WIRS_1 1346 1351 PF05994 0.474
LIG_WRC_WIRS_1 147 152 PF05994 0.418
LIG_WRC_WIRS_1 209 214 PF05994 0.545
LIG_WRC_WIRS_1 386 391 PF05994 0.545
LIG_WRC_WIRS_1 590 595 PF05994 0.310
MOD_CK1_1 1020 1026 PF00069 0.620
MOD_CK1_1 1048 1054 PF00069 0.591
MOD_CK1_1 1059 1065 PF00069 0.561
MOD_CK1_1 146 152 PF00069 0.418
MOD_CK1_1 178 184 PF00069 0.268
MOD_CK1_1 461 467 PF00069 0.461
MOD_CK1_1 505 511 PF00069 0.444
MOD_CK1_1 52 58 PF00069 0.559
MOD_CK1_1 604 610 PF00069 0.362
MOD_CK1_1 678 684 PF00069 0.299
MOD_CK1_1 715 721 PF00069 0.218
MOD_CK1_1 796 802 PF00069 0.516
MOD_CK1_1 841 847 PF00069 0.522
MOD_CK1_1 862 868 PF00069 0.607
MOD_CK1_1 961 967 PF00069 0.753
MOD_CK1_1 968 974 PF00069 0.700
MOD_CK1_1 979 985 PF00069 0.580
MOD_CK2_1 1039 1045 PF00069 0.770
MOD_CK2_1 123 129 PF00069 0.601
MOD_CK2_1 1271 1277 PF00069 0.484
MOD_CK2_1 1329 1335 PF00069 0.533
MOD_CK2_1 1339 1345 PF00069 0.481
MOD_CK2_1 217 223 PF00069 0.574
MOD_CK2_1 299 305 PF00069 0.505
MOD_CK2_1 451 457 PF00069 0.591
MOD_CK2_1 547 553 PF00069 0.341
MOD_CK2_1 554 560 PF00069 0.338
MOD_CK2_1 583 589 PF00069 0.298
MOD_CK2_1 708 714 PF00069 0.276
MOD_CK2_1 796 802 PF00069 0.516
MOD_CK2_1 880 886 PF00069 0.573
MOD_CK2_1 968 974 PF00069 0.685
MOD_Cter_Amidation 36 39 PF01082 0.460
MOD_GlcNHglycan 1095 1098 PF01048 0.275
MOD_GlcNHglycan 1227 1230 PF01048 0.274
MOD_GlcNHglycan 1263 1266 PF01048 0.274
MOD_GlcNHglycan 190 193 PF01048 0.458
MOD_GlcNHglycan 262 265 PF01048 0.274
MOD_GlcNHglycan 323 326 PF01048 0.286
MOD_GlcNHglycan 423 426 PF01048 0.322
MOD_GlcNHglycan 451 454 PF01048 0.342
MOD_GlcNHglycan 74 77 PF01048 0.347
MOD_GlcNHglycan 777 780 PF01048 0.341
MOD_GlcNHglycan 840 843 PF01048 0.328
MOD_GlcNHglycan 861 864 PF01048 0.402
MOD_GlcNHglycan 911 914 PF01048 0.451
MOD_GlcNHglycan 994 998 PF01048 0.400
MOD_GSK3_1 1017 1024 PF00069 0.652
MOD_GSK3_1 1025 1032 PF00069 0.672
MOD_GSK3_1 1039 1046 PF00069 0.716
MOD_GSK3_1 1055 1062 PF00069 0.522
MOD_GSK3_1 1093 1100 PF00069 0.526
MOD_GSK3_1 1129 1136 PF00069 0.474
MOD_GSK3_1 1147 1154 PF00069 0.474
MOD_GSK3_1 1221 1228 PF00069 0.498
MOD_GSK3_1 1263 1270 PF00069 0.471
MOD_GSK3_1 13 20 PF00069 0.587
MOD_GSK3_1 142 149 PF00069 0.449
MOD_GSK3_1 173 180 PF00069 0.301
MOD_GSK3_1 218 225 PF00069 0.605
MOD_GSK3_1 260 267 PF00069 0.527
MOD_GSK3_1 317 324 PF00069 0.500
MOD_GSK3_1 344 351 PF00069 0.544
MOD_GSK3_1 359 366 PF00069 0.491
MOD_GSK3_1 381 388 PF00069 0.505
MOD_GSK3_1 407 414 PF00069 0.592
MOD_GSK3_1 419 426 PF00069 0.514
MOD_GSK3_1 449 456 PF00069 0.547
MOD_GSK3_1 458 465 PF00069 0.552
MOD_GSK3_1 504 511 PF00069 0.501
MOD_GSK3_1 51 58 PF00069 0.551
MOD_GSK3_1 597 604 PF00069 0.340
MOD_GSK3_1 631 638 PF00069 0.323
MOD_GSK3_1 675 682 PF00069 0.301
MOD_GSK3_1 708 715 PF00069 0.240
MOD_GSK3_1 763 770 PF00069 0.523
MOD_GSK3_1 859 866 PF00069 0.664
MOD_GSK3_1 877 884 PF00069 0.505
MOD_GSK3_1 924 931 PF00069 0.536
MOD_GSK3_1 961 968 PF00069 0.811
MOD_GSK3_1 972 979 PF00069 0.712
MOD_N-GLC_1 1005 1010 PF02516 0.379
MOD_N-GLC_1 13 18 PF02516 0.346
MOD_N-GLC_1 218 223 PF02516 0.421
MOD_N-GLC_1 338 343 PF02516 0.412
MOD_N-GLC_1 348 353 PF02516 0.278
MOD_N-GLC_1 363 368 PF02516 0.291
MOD_N-GLC_1 449 454 PF02516 0.316
MOD_N-GLC_1 462 467 PF02516 0.310
MOD_N-GLC_1 478 483 PF02516 0.283
MOD_N-GLC_1 7 12 PF02516 0.322
MOD_NEK2_1 1056 1061 PF00069 0.521
MOD_NEK2_1 1199 1204 PF00069 0.474
MOD_NEK2_1 1245 1250 PF00069 0.486
MOD_NEK2_1 1271 1276 PF00069 0.474
MOD_NEK2_1 15 20 PF00069 0.645
MOD_NEK2_1 234 239 PF00069 0.466
MOD_NEK2_1 245 250 PF00069 0.530
MOD_NEK2_1 260 265 PF00069 0.498
MOD_NEK2_1 478 483 PF00069 0.508
MOD_NEK2_1 502 507 PF00069 0.490
MOD_NEK2_1 552 557 PF00069 0.347
MOD_NEK2_1 59 64 PF00069 0.532
MOD_NEK2_1 696 701 PF00069 0.307
MOD_NEK2_1 7 12 PF00069 0.665
MOD_NEK2_1 730 735 PF00069 0.321
MOD_NEK2_1 751 756 PF00069 0.507
MOD_NEK2_1 774 779 PF00069 0.516
MOD_NEK2_1 87 92 PF00069 0.585
MOD_NEK2_1 878 883 PF00069 0.514
MOD_NEK2_1 924 929 PF00069 0.617
MOD_NEK2_2 1087 1092 PF00069 0.519
MOD_NEK2_2 1166 1171 PF00069 0.474
MOD_PIKK_1 1151 1157 PF00454 0.474
MOD_PIKK_1 193 199 PF00454 0.310
MOD_PIKK_1 284 290 PF00454 0.456
MOD_PIKK_1 663 669 PF00454 0.297
MOD_PIKK_1 687 693 PF00454 0.304
MOD_PIKK_1 744 750 PF00454 0.559
MOD_PIKK_1 793 799 PF00454 0.614
MOD_PIKK_1 881 887 PF00454 0.523
MOD_PKA_2 1245 1251 PF00069 0.488
MOD_PKA_2 1339 1345 PF00069 0.503
MOD_PKA_2 178 184 PF00069 0.290
MOD_PKA_2 461 467 PF00069 0.456
MOD_PKA_2 481 487 PF00069 0.430
MOD_PKA_2 547 553 PF00069 0.337
MOD_PKA_2 736 742 PF00069 0.561
MOD_PKA_2 928 934 PF00069 0.522
MOD_PKA_2 958 964 PF00069 0.643
MOD_Plk_1 1020 1026 PF00069 0.588
MOD_Plk_1 1056 1062 PF00069 0.536
MOD_Plk_1 13 19 PF00069 0.548
MOD_Plk_1 218 224 PF00069 0.626
MOD_Plk_1 245 251 PF00069 0.417
MOD_Plk_1 317 323 PF00069 0.502
MOD_Plk_1 338 344 PF00069 0.620
MOD_Plk_1 381 387 PF00069 0.511
MOD_Plk_1 462 468 PF00069 0.523
MOD_Plk_1 478 484 PF00069 0.410
MOD_Plk_1 55 61 PF00069 0.550
MOD_Plk_1 583 589 PF00069 0.321
MOD_Plk_1 635 641 PF00069 0.392
MOD_Plk_1 793 799 PF00069 0.501
MOD_Plk_1 87 93 PF00069 0.542
MOD_Plk_1 976 982 PF00069 0.634
MOD_Plk_2-3 129 135 PF00069 0.612
MOD_Plk_2-3 299 305 PF00069 0.494
MOD_Plk_2-3 451 457 PF00069 0.579
MOD_Plk_2-3 606 612 PF00069 0.340
MOD_Plk_4 1045 1051 PF00069 0.613
MOD_Plk_4 1056 1062 PF00069 0.555
MOD_Plk_4 1087 1093 PF00069 0.567
MOD_Plk_4 1153 1159 PF00069 0.485
MOD_Plk_4 149 155 PF00069 0.233
MOD_Plk_4 198 204 PF00069 0.283
MOD_Plk_4 234 240 PF00069 0.507
MOD_Plk_4 350 356 PF00069 0.504
MOD_Plk_4 385 391 PF00069 0.481
MOD_Plk_4 392 398 PF00069 0.468
MOD_Plk_4 462 468 PF00069 0.454
MOD_Plk_4 514 520 PF00069 0.310
MOD_Plk_4 59 65 PF00069 0.487
MOD_Plk_4 680 686 PF00069 0.322
MOD_ProDKin_1 1030 1036 PF00069 0.608
MOD_ProDKin_1 1043 1049 PF00069 0.563
MOD_ProDKin_1 1250 1256 PF00069 0.474
MOD_ProDKin_1 267 273 PF00069 0.588
MOD_ProDKin_1 918 924 PF00069 0.575
MOD_ProDKin_1 963 969 PF00069 0.695
MOD_ProDKin_1 972 978 PF00069 0.646
MOD_SUMO_for_1 1125 1128 PF00179 0.474
MOD_SUMO_rev_2 108 116 PF00179 0.559
MOD_SUMO_rev_2 1201 1210 PF00179 0.474
MOD_SUMO_rev_2 609 618 PF00179 0.389
MOD_SUMO_rev_2 825 835 PF00179 0.525
TRG_DiLeu_BaEn_1 538 543 PF01217 0.280
TRG_DiLeu_BaEn_2 1044 1050 PF01217 0.643
TRG_DiLeu_BaEn_2 588 594 PF01217 0.304
TRG_DiLeu_BaLyEn_6 250 255 PF01217 0.425
TRG_DiLeu_BaLyEn_6 289 294 PF01217 0.450
TRG_DiLeu_LyEn_5 538 543 PF01217 0.280
TRG_ENDOCYTIC_2 1103 1106 PF00928 0.503
TRG_ENDOCYTIC_2 1157 1160 PF00928 0.479
TRG_ENDOCYTIC_2 251 254 PF00928 0.481
TRG_ENDOCYTIC_2 266 269 PF00928 0.553
TRG_ENDOCYTIC_2 312 315 PF00928 0.521
TRG_ENDOCYTIC_2 354 357 PF00928 0.509
TRG_ENDOCYTIC_2 868 871 PF00928 0.519
TRG_ER_diArg_1 1185 1187 PF00400 0.474
TRG_ER_diArg_1 38 40 PF00400 0.595
TRG_ER_diArg_1 619 622 PF00400 0.345
TRG_ER_diArg_1 716 719 PF00400 0.351
TRG_NLS_MonoExtN_4 957 963 PF00514 0.586
TRG_Pf-PMV_PEXEL_1 1123 1127 PF00026 0.275
TRG_Pf-PMV_PEXEL_1 253 257 PF00026 0.223
TRG_Pf-PMV_PEXEL_1 541 545 PF00026 0.502
TRG_Pf-PMV_PEXEL_1 574 578 PF00026 0.529
TRG_Pf-PMV_PEXEL_1 585 589 PF00026 0.457

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7M0 Leptomonas seymouri 63% 88%
A0A3S7X5A9 Leishmania donovani 81% 100%
A4I7P7 Leishmania infantum 82% 99%
E9B2K5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 99%
Q4Q5K1 Leishmania major 81% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS