LeishMANIAdb
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Presequence translocated-associated motor subunit PAM16

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Presequence translocated-associated motor subunit PAM16
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HJZ7_LEIBR
TriTrypDb:
LbrM.32.0230 , LBRM2903_320007000
Length:
90

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005739 mitochondrion 5 1
GO:0020023 kinetoplast 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HJZ7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJZ7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 51 53 PF00675 0.600
CLV_NRD_NRD_1 68 70 PF00675 0.414
CLV_NRD_NRD_1 84 86 PF00675 0.532
DEG_Nend_Nbox_1 1 3 PF02207 0.540
DOC_USP7_UBL2_3 82 86 PF12436 0.461
DOC_WW_Pin1_4 84 89 PF00397 0.635
LIG_14-3-3_CanoR_1 9 19 PF00244 0.586
LIG_BRCT_BRCA1_1 15 19 PF00533 0.436
LIG_FHA_2 61 67 PF00498 0.550
LIG_LIR_Gen_1 40 48 PF02991 0.499
LIG_LIR_Nem_3 49 54 PF02991 0.442
LIG_SH2_CRK 51 55 PF00017 0.462
LIG_SH3_3 29 35 PF00018 0.421
MOD_CK2_1 17 23 PF00069 0.570
MOD_CK2_1 34 40 PF00069 0.531
MOD_CK2_1 60 66 PF00069 0.507
MOD_GlcNHglycan 36 39 PF01048 0.466
MOD_GSK3_1 13 20 PF00069 0.535
MOD_N-GLC_2 73 75 PF02516 0.551
MOD_NEK2_1 1 6 PF00069 0.644
MOD_NEK2_1 77 82 PF00069 0.589
MOD_PKA_1 17 23 PF00069 0.524
MOD_ProDKin_1 84 90 PF00069 0.645
TRG_DiLeu_BaEn_4 49 55 PF01217 0.425
TRG_ENDOCYTIC_2 41 44 PF00928 0.421
TRG_ENDOCYTIC_2 51 54 PF00928 0.413
TRG_Pf-PMV_PEXEL_1 52 56 PF00026 0.523

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P8J9 Leptomonas seymouri 78% 95%
A0A0S4ISH5 Bodo saltans 53% 98%
A0A1X0P6S9 Trypanosomatidae 57% 76%
A0A3Q8IGP9 Leishmania donovani 85% 99%
A0A422P0X8 Trypanosoma rangeli 57% 81%
A4I7I0 Leishmania infantum 87% 99%
D0A083 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 49% 93%
E9B2D7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 99%
Q4Q5R9 Leishmania major 87% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS