EF-hand domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HJX7_LEIBR

TriTrypDb:

LbrM.32.0020 , LBRM2903_320005400

Length:

Annotations

LeishMANIAdb annotations

A protein with unclear topology, conserved but entirely restricted to Kinetoplastida.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJX7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJX7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	56	58	PF00675	0.368
CLV_NRD_NRD_1	59	61	PF00675	0.552
CLV_PCSK_KEX2_1	56	58	PF00082	0.368
DOC_USP7_MATH_1	69	73	PF00917	0.299
DOC_USP7_MATH_1	79	83	PF00917	0.283
LIG_14-3-3_CanoR_1	24	29	PF00244	0.371
LIG_BRCT_BRCA1_1	81	85	PF00533	0.313
LIG_LIR_Gen_1	46	54	PF02991	0.358
LIG_LIR_Gen_1	5	14	PF02991	0.288
LIG_LIR_Nem_3	13	17	PF02991	0.544
LIG_LIR_Nem_3	5	9	PF02991	0.441
LIG_SH2_STAT5	20	23	PF00017	0.325
LIG_SH3_3	33	39	PF00018	0.373
LIG_WRC_WIRS_1	11	16	PF05994	0.285
MOD_CK1_1	27	33	PF00069	0.379
MOD_N-GLC_1	24	29	PF02516	0.358
MOD_NEK2_1	12	17	PF00069	0.469
MOD_NEK2_2	69	74	PF00069	0.304
MOD_Plk_1	24	30	PF00069	0.354
MOD_Plk_4	79	85	PF00069	0.308
TRG_ER_diArg_1	56	58	PF00400	0.368

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4J967	Bodo saltans	39%	66%