LeishMANIAdb
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BRCT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
BRCT domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4HJU2_LEIBR
TriTrypDb:
LbrM.31.3400 * , LBRM2903_310044200 * , LBRM2903_310044300 *
Length:
695

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJU2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJU2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 130 134 PF00656 0.848
CLV_C14_Caspase3-7 550 554 PF00656 0.862
CLV_NRD_NRD_1 174 176 PF00675 0.827
CLV_NRD_NRD_1 18 20 PF00675 0.814
CLV_NRD_NRD_1 278 280 PF00675 0.880
CLV_NRD_NRD_1 329 331 PF00675 0.850
CLV_NRD_NRD_1 385 387 PF00675 0.834
CLV_NRD_NRD_1 405 407 PF00675 0.506
CLV_PCSK_KEX2_1 174 176 PF00082 0.827
CLV_PCSK_KEX2_1 18 20 PF00082 0.814
CLV_PCSK_KEX2_1 278 280 PF00082 0.880
CLV_PCSK_KEX2_1 329 331 PF00082 0.850
CLV_PCSK_KEX2_1 385 387 PF00082 0.834
CLV_PCSK_KEX2_1 405 407 PF00082 0.506
CLV_PCSK_PC7_1 274 280 PF00082 0.876
CLV_PCSK_SKI1_1 129 133 PF00082 0.846
CLV_PCSK_SKI1_1 329 333 PF00082 0.855
DEG_APCC_DBOX_1 128 136 PF00400 0.850
DEG_APCC_DBOX_1 238 246 PF00400 0.864
DEG_SCF_FBW7_1 445 451 PF00400 0.826
DEG_SPOP_SBC_1 677 681 PF00917 0.838
DOC_CDC14_PxL_1 632 640 PF14671 0.832
DOC_CKS1_1 445 450 PF01111 0.824
DOC_MAPK_MEF2A_6 291 300 PF00069 0.855
DOC_PP2B_LxvP_1 135 138 PF13499 0.854
DOC_PP2B_LxvP_1 559 562 PF13499 0.843
DOC_PP2B_LxvP_1 56 59 PF13499 0.827
DOC_SPAK_OSR1_1 279 283 PF12202 0.879
DOC_SPAK_OSR1_1 690 694 PF12202 0.803
DOC_USP7_MATH_1 131 135 PF00917 0.848
DOC_USP7_MATH_1 198 202 PF00917 0.871
DOC_USP7_MATH_1 206 210 PF00917 0.728
DOC_USP7_MATH_1 23 27 PF00917 0.830
DOC_USP7_MATH_1 235 239 PF00917 0.860
DOC_USP7_MATH_1 281 285 PF00917 0.873
DOC_USP7_MATH_1 323 327 PF00917 0.852
DOC_USP7_MATH_1 409 413 PF00917 0.865
DOC_USP7_MATH_1 427 431 PF00917 0.536
DOC_USP7_MATH_1 448 452 PF00917 0.829
DOC_USP7_MATH_1 453 457 PF00917 0.758
DOC_USP7_MATH_1 587 591 PF00917 0.857
DOC_USP7_MATH_1 663 667 PF00917 0.831
DOC_USP7_MATH_2 459 465 PF00917 0.847
DOC_WW_Pin1_4 144 149 PF00397 0.860
DOC_WW_Pin1_4 259 264 PF00397 0.863
DOC_WW_Pin1_4 337 342 PF00397 0.853
DOC_WW_Pin1_4 444 449 PF00397 0.824
DOC_WW_Pin1_4 472 477 PF00397 0.847
DOC_WW_Pin1_4 506 511 PF00397 0.852
DOC_WW_Pin1_4 519 524 PF00397 0.617
DOC_WW_Pin1_4 580 585 PF00397 0.847
DOC_WW_Pin1_4 640 645 PF00397 0.850
DOC_WW_Pin1_4 647 652 PF00397 0.738
DOC_WW_Pin1_4 653 658 PF00397 0.618
DOC_WW_Pin1_4 83 88 PF00397 0.834
LIG_14-3-3_CanoR_1 334 338 PF00244 0.863
LIG_14-3-3_CanoR_1 413 421 PF00244 0.873
LIG_14-3-3_CanoR_1 484 490 PF00244 0.863
LIG_14-3-3_CanoR_1 529 535 PF00244 0.873
LIG_14-3-3_CanoR_1 557 562 PF00244 0.848
LIG_14-3-3_CanoR_1 608 618 PF00244 0.854
LIG_14-3-3_CanoR_1 646 651 PF00244 0.865
LIG_14-3-3_CanoR_1 661 670 PF00244 0.574
LIG_14-3-3_CanoR_1 94 99 PF00244 0.867
LIG_BRCT_BRCA1_1 655 659 PF00533 0.843
LIG_EVH1_1 267 271 PF00568 0.867
LIG_EVH1_1 56 60 PF00568 0.828
LIG_EVH1_2 276 280 PF00568 0.874
LIG_FHA_1 103 109 PF00498 0.849
LIG_FHA_1 168 174 PF00498 0.823
LIG_FHA_1 253 259 PF00498 0.867
LIG_FHA_1 270 276 PF00498 0.570
LIG_FHA_1 291 297 PF00498 0.852
LIG_FHA_1 453 459 PF00498 0.841
LIG_FHA_1 507 513 PF00498 0.852
LIG_FHA_1 530 536 PF00498 0.870
LIG_FHA_1 554 560 PF00498 0.854
LIG_FHA_1 581 587 PF00498 0.853
LIG_FHA_1 627 633 PF00498 0.828
LIG_FHA_2 290 296 PF00498 0.856
LIG_FHA_2 342 348 PF00498 0.862
LIG_FHA_2 577 583 PF00498 0.843
LIG_FHA_2 622 628 PF00498 0.826
LIG_Integrin_isoDGR_2 491 493 PF01839 0.869
LIG_LIR_Nem_3 522 528 PF02991 0.852
LIG_LIR_Nem_3 689 694 PF02991 0.804
LIG_PCNA_yPIPBox_3 106 114 PF02747 0.850
LIG_SH2_CRK 525 529 PF00017 0.869
LIG_SH2_STAT3 119 122 PF00017 0.843
LIG_SH3_1 114 120 PF00018 0.835
LIG_SH3_3 114 120 PF00018 0.835
LIG_SH3_3 142 148 PF00018 0.861
LIG_SH3_3 257 263 PF00018 0.863
LIG_SH3_3 265 271 PF00018 0.731
LIG_SH3_3 300 306 PF00018 0.843
LIG_SH3_3 335 341 PF00018 0.857
LIG_SH3_3 518 524 PF00018 0.846
LIG_SH3_3 54 60 PF00018 0.834
LIG_SH3_3 542 548 PF00018 0.871
LIG_SH3_3 581 587 PF00018 0.853
LIG_SH3_3 86 92 PF00018 0.843
LIG_TRAF2_1 579 582 PF00917 0.839
LIG_TRAF2_1 603 606 PF00917 0.860
LIG_WW_3 275 279 PF00397 0.874
MOD_CDC14_SPxK_1 643 646 PF00782 0.862
MOD_CDK_SPxK_1 444 450 PF00069 0.826
MOD_CDK_SPxK_1 640 646 PF00069 0.854
MOD_CDK_SPxxK_3 472 479 PF00069 0.849
MOD_CK1_1 26 32 PF00069 0.829
MOD_CK1_1 336 342 PF00069 0.856
MOD_CK1_1 34 40 PF00069 0.685
MOD_CK1_1 376 382 PF00069 0.841
MOD_CK1_1 414 420 PF00069 0.872
MOD_CK1_1 440 446 PF00069 0.827
MOD_CK1_1 519 525 PF00069 0.847
MOD_CK1_1 552 558 PF00069 0.853
MOD_CK1_1 621 627 PF00069 0.825
MOD_CK1_1 640 646 PF00069 0.522
MOD_CK1_1 649 655 PF00069 0.699
MOD_CK1_1 662 668 PF00069 0.607
MOD_CK2_1 24 30 PF00069 0.832
MOD_CK2_1 240 246 PF00069 0.863
MOD_CK2_1 341 347 PF00069 0.859
MOD_CK2_1 472 478 PF00069 0.847
MOD_CK2_1 576 582 PF00069 0.840
MOD_CK2_1 600 606 PF00069 0.860
MOD_GlcNHglycan 142 145 PF01048 0.859
MOD_GlcNHglycan 151 154 PF01048 0.658
MOD_GlcNHglycan 195 198 PF01048 0.875
MOD_GlcNHglycan 204 207 PF01048 0.714
MOD_GlcNHglycan 208 211 PF01048 0.637
MOD_GlcNHglycan 222 225 PF01048 0.553
MOD_GlcNHglycan 324 328 PF01048 0.846
MOD_GlcNHglycan 417 420 PF01048 0.871
MOD_GlcNHglycan 429 432 PF01048 0.641
MOD_GlcNHglycan 437 440 PF01048 0.488
MOD_GlcNHglycan 455 458 PF01048 0.531
MOD_GlcNHglycan 478 482 PF01048 0.854
MOD_GlcNHglycan 559 562 PF01048 0.843
MOD_GlcNHglycan 589 593 PF01048 0.852
MOD_GlcNHglycan 624 627 PF01048 0.823
MOD_GlcNHglycan 661 664 PF01048 0.840
MOD_GSK3_1 140 147 PF00069 0.861
MOD_GSK3_1 193 200 PF00069 0.876
MOD_GSK3_1 202 209 PF00069 0.707
MOD_GSK3_1 241 248 PF00069 0.863
MOD_GSK3_1 332 339 PF00069 0.864
MOD_GSK3_1 376 383 PF00069 0.840
MOD_GSK3_1 407 414 PF00069 0.864
MOD_GSK3_1 440 447 PF00069 0.828
MOD_GSK3_1 448 455 PF00069 0.695
MOD_GSK3_1 457 464 PF00069 0.546
MOD_GSK3_1 502 509 PF00069 0.855
MOD_GSK3_1 543 550 PF00069 0.869
MOD_GSK3_1 553 560 PF00069 0.680
MOD_GSK3_1 576 583 PF00069 0.841
MOD_GSK3_1 618 625 PF00069 0.834
MOD_GSK3_1 646 653 PF00069 0.861
MOD_GSK3_1 659 666 PF00069 0.614
MOD_GSK3_1 676 683 PF00069 0.544
MOD_GSK3_1 90 97 PF00069 0.863
MOD_GSK3_1 98 105 PF00069 0.711
MOD_N-GLC_1 461 466 PF02516 0.857
MOD_N-GLC_1 61 66 PF02516 0.818
MOD_N-GLC_1 653 658 PF02516 0.845
MOD_N-GLC_1 7 12 PF02516 0.800
MOD_N-GLC_1 83 88 PF02516 0.834
MOD_NEK2_1 140 145 PF00069 0.859
MOD_NEK2_1 332 337 PF00069 0.870
MOD_NEK2_1 435 440 PF00069 0.840
MOD_NEK2_1 452 457 PF00069 0.550
MOD_NEK2_1 477 482 PF00069 0.852
MOD_NEK2_1 588 593 PF00069 0.855
MOD_NEK2_1 618 623 PF00069 0.837
MOD_NEK2_1 659 664 PF00069 0.843
MOD_NEK2_2 131 136 PF00069 0.851
MOD_NEK2_2 463 468 PF00069 0.867
MOD_NEK2_2 663 668 PF00069 0.833
MOD_PIKK_1 100 106 PF00454 0.849
MOD_PIKK_1 37 43 PF00454 0.821
MOD_PIKK_1 440 446 PF00454 0.827
MOD_PIKK_1 543 549 PF00454 0.869
MOD_PIKK_1 61 67 PF00454 0.818
MOD_PK_1 299 305 PF00069 0.849
MOD_PK_1 373 379 PF00069 0.839
MOD_PKA_2 188 194 PF00069 0.867
MOD_PKA_2 333 339 PF00069 0.865
MOD_PKA_2 414 420 PF00069 0.872
MOD_PKA_2 528 534 PF00069 0.873
MOD_PKA_2 576 582 PF00069 0.840
MOD_PKA_2 607 613 PF00069 0.854
MOD_PKB_1 413 421 PF00069 0.873
MOD_Plk_1 29 35 PF00069 0.833
MOD_Plk_1 37 43 PF00069 0.681
MOD_Plk_1 448 454 PF00069 0.834
MOD_Plk_1 477 483 PF00069 0.852
MOD_Plk_1 588 594 PF00069 0.853
MOD_Plk_1 61 67 PF00069 0.818
MOD_Plk_1 618 624 PF00069 0.835
MOD_Plk_1 626 632 PF00069 0.687
MOD_Plk_1 7 13 PF00069 0.799
MOD_Plk_2-3 188 194 PF00069 0.867
MOD_Plk_2-3 290 296 PF00069 0.856
MOD_Plk_2-3 600 606 PF00069 0.860
MOD_Plk_4 376 382 PF00069 0.841
MOD_Plk_4 437 443 PF00069 0.832
MOD_Plk_4 663 669 PF00069 0.835
MOD_ProDKin_1 144 150 PF00069 0.858
MOD_ProDKin_1 259 265 PF00069 0.864
MOD_ProDKin_1 337 343 PF00069 0.854
MOD_ProDKin_1 444 450 PF00069 0.826
MOD_ProDKin_1 472 478 PF00069 0.847
MOD_ProDKin_1 506 512 PF00069 0.854
MOD_ProDKin_1 519 525 PF00069 0.620
MOD_ProDKin_1 580 586 PF00069 0.848
MOD_ProDKin_1 640 646 PF00069 0.854
MOD_ProDKin_1 647 653 PF00069 0.736
MOD_ProDKin_1 83 89 PF00069 0.834
MOD_SUMO_rev_2 382 392 PF00179 0.831
TRG_DiLeu_BaLyEn_6 507 512 PF01217 0.851
TRG_DiLeu_BaLyEn_6 91 96 PF01217 0.864
TRG_ENDOCYTIC_2 525 528 PF00928 0.865
TRG_ER_diArg_1 17 19 PF00400 0.808
TRG_ER_diArg_1 173 175 PF00400 0.834
TRG_ER_diArg_1 277 279 PF00400 0.877
TRG_ER_diArg_1 384 386 PF00400 0.841
TRG_ER_diArg_1 518 521 PF00400 0.855
TRG_Pf-PMV_PEXEL_1 94 98 PF00026 0.873

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS