Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HJT0_LEIBR

TriTrypDb:

LbrM.31.3280 , LBRM2903_310042700

Length:

246

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJT0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJT0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.677
CLV_NRD_NRD_1	106	108	PF00675	0.536
CLV_NRD_NRD_1	16	18	PF00675	0.404
CLV_NRD_NRD_1	213	215	PF00675	0.684
CLV_NRD_NRD_1	244	246	PF00675	0.681
CLV_NRD_NRD_1	61	63	PF00675	0.514
CLV_NRD_NRD_1	91	93	PF00675	0.568
CLV_PCSK_KEX2_1	105	107	PF00082	0.543
CLV_PCSK_KEX2_1	213	215	PF00082	0.684
CLV_PCSK_KEX2_1	244	246	PF00082	0.681
CLV_PCSK_KEX2_1	61	63	PF00082	0.514
CLV_PCSK_KEX2_1	91	93	PF00082	0.568
CLV_PCSK_SKI1_1	42	46	PF00082	0.559
DEG_APCC_DBOX_1	176	184	PF00400	0.509
DEG_APCC_DBOX_1	41	49	PF00400	0.530
DOC_CDC14_PxL_1	156	164	PF14671	0.525
DOC_WW_Pin1_4	184	189	PF00397	0.556
DOC_WW_Pin1_4	4	9	PF00397	0.663
DOC_WW_Pin1_4	53	58	PF00397	0.704
LIG_14-3-3_CanoR_1	17	26	PF00244	0.568
LIG_14-3-3_CanoR_1	177	181	PF00244	0.510
LIG_14-3-3_CanoR_1	221	228	PF00244	0.637
LIG_14-3-3_CanoR_1	99	105	PF00244	0.648
LIG_BRCT_BRCA1_1	65	69	PF00533	0.636
LIG_eIF4E_1	41	47	PF01652	0.530
LIG_FHA_1	151	157	PF00498	0.588
LIG_FHA_1	177	183	PF00498	0.575
LIG_FHA_1	185	191	PF00498	0.606
LIG_FHA_2	129	135	PF00498	0.608
LIG_LIR_LC3C_4	179	182	PF02991	0.506
LIG_SH2_STAT5	142	145	PF00017	0.559
LIG_SH2_STAT5	51	54	PF00017	0.647
LIG_SH3_2	209	214	PF14604	0.670
LIG_SH3_3	206	212	PF00018	0.712
LIG_SUMO_SIM_anti_2	179	184	PF11976	0.509
MOD_CDK_SPxK_1	4	10	PF00069	0.660
MOD_CK1_1	145	151	PF00069	0.555
MOD_CK1_1	170	176	PF00069	0.663
MOD_CK1_1	224	230	PF00069	0.689
MOD_CK1_1	33	39	PF00069	0.544
MOD_CK1_1	56	62	PF00069	0.657
MOD_CK1_1	67	73	PF00069	0.542
MOD_CK2_1	67	73	PF00069	0.657
MOD_Cter_Amidation	242	245	PF01082	0.683
MOD_GlcNHglycan	148	151	PF01048	0.581
MOD_GlcNHglycan	164	167	PF01048	0.636
MOD_GlcNHglycan	169	172	PF01048	0.615
MOD_GlcNHglycan	19	22	PF01048	0.543
MOD_GlcNHglycan	236	239	PF01048	0.571
MOD_GlcNHglycan	66	69	PF01048	0.660
MOD_GSK3_1	141	148	PF00069	0.719
MOD_GSK3_1	150	157	PF00069	0.603
MOD_GSK3_1	162	169	PF00069	0.617
MOD_GSK3_1	63	70	PF00069	0.573
MOD_NEK2_1	162	167	PF00069	0.651
MOD_NEK2_1	71	76	PF00069	0.465
MOD_NEK2_1	84	89	PF00069	0.523
MOD_NEK2_2	100	105	PF00069	0.655
MOD_PIKK_1	142	148	PF00454	0.561
MOD_PKA_1	17	23	PF00069	0.377
MOD_PKA_2	176	182	PF00069	0.508
MOD_PKA_2	30	36	PF00069	0.544
MOD_Plk_1	113	119	PF00069	0.542
MOD_Plk_4	176	182	PF00069	0.508
MOD_ProDKin_1	184	190	PF00069	0.556
MOD_ProDKin_1	4	10	PF00069	0.660
MOD_ProDKin_1	53	59	PF00069	0.711
TRG_DiLeu_BaLyEn_6	157	162	PF01217	0.525
TRG_ER_diArg_1	104	107	PF00400	0.691
TRG_ER_diArg_1	212	214	PF00400	0.784
TRG_ER_diArg_1	216	219	PF00400	0.740
TRG_ER_diArg_1	61	63	PF00400	0.514

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGF1	Leishmania donovani	72%	100%
A4I796	Leishmania infantum	74%	100%
E9B291	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	99%
Q4Q5W7	Leishmania major	74%	100%