ADP-ribosylation factor

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylation factor, putative

Species:

Leishmania braziliensis

UniProt:

A4HJR7_LEIBR

TriTrypDb:

LbrM.31.3150 , LBRM2903_310041400

Length:

178

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0005794	Golgi apparatus	5	13
GO:0043226	organelle	2	13
GO:0043227	membrane-bounded organelle	3	13
GO:0043229	intracellular organelle	3	13
GO:0043231	intracellular membrane-bounded organelle	4	13
GO:0110165	cellular anatomical entity	1	13

Expansion

Sequence features

A4HJR7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJR7

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	13
GO:0008104	protein localization	4	13
GO:0009987	cellular process	1	13
GO:0015031	protein transport	4	13
GO:0016192	vesicle-mediated transport	4	13
GO:0033036	macromolecule localization	2	13
GO:0045184	establishment of protein localization	3	13
GO:0051179	localization	1	13
GO:0051234	establishment of localization	2	13
GO:0051641	cellular localization	2	13
GO:0070727	cellular macromolecule localization	3	13
GO:0071702	organic substance transport	4	13
GO:0071705	nitrogen compound transport	4	13
GO:0006886	intracellular protein transport	4	1
GO:0046907	intracellular transport	3	1
GO:0051649	establishment of localization in cell	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	14
GO:0003824	catalytic activity	1	14
GO:0003924	GTPase activity	7	14
GO:0005488	binding	1	14
GO:0005525	GTP binding	5	14
GO:0016462	pyrophosphatase activity	5	14
GO:0016787	hydrolase activity	2	14
GO:0016817	hydrolase activity, acting on acid anhydrides	3	14
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	14
GO:0017076	purine nucleotide binding	4	14
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	14
GO:0019001	guanyl nucleotide binding	5	14
GO:0032553	ribonucleotide binding	3	14
GO:0032555	purine ribonucleotide binding	4	14
GO:0032561	guanyl ribonucleotide binding	5	14
GO:0035639	purine ribonucleoside triphosphate binding	4	14
GO:0036094	small molecule binding	2	14
GO:0043167	ion binding	2	14
GO:0043168	anion binding	3	14
GO:0097159	organic cyclic compound binding	2	14
GO:0097367	carbohydrate derivative binding	2	14
GO:1901265	nucleoside phosphate binding	3	14
GO:1901363	heterocyclic compound binding	2	14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	113	117	PF00082	0.361
CLV_PCSK_SKI1_1	55	59	PF00082	0.292
CLV_PCSK_SKI1_1	97	101	PF00082	0.299
DEG_SPOP_SBC_1	129	133	PF00917	0.303
DOC_MAPK_gen_1	11	21	PF00069	0.461
DOC_MAPK_HePTP_8	9	21	PF00069	0.452
DOC_MAPK_MEF2A_6	11	18	PF00069	0.303
DOC_PP1_RVXF_1	53	60	PF00149	0.292
LIG_14-3-3_CanoR_1	113	118	PF00244	0.452
LIG_Actin_WH2_2	42	60	PF00022	0.295
LIG_Actin_WH2_2	99	115	PF00022	0.292
LIG_BIR_III_4	22	26	PF00653	0.303
LIG_FHA_1	114	120	PF00498	0.452
LIG_FHA_1	130	136	PF00498	0.303
LIG_FHA_1	25	31	PF00498	0.303
LIG_FHA_1	79	85	PF00498	0.292
LIG_FHA_2	58	64	PF00498	0.328
LIG_LIR_Gen_1	167	173	PF02991	0.331
LIG_LIR_Nem_3	167	171	PF02991	0.331
LIG_LIR_Nem_3	51	57	PF02991	0.292
LIG_NRBOX	4	10	PF00104	0.452
LIG_Pex14_1	74	78	PF04695	0.328
LIG_PTB_Apo_2	53	60	PF02174	0.292
LIG_SH2_CRK	54	58	PF00017	0.292
LIG_SH2_GRB2like	78	81	PF00017	0.303
LIG_SH2_STAT5	150	153	PF00017	0.316
LIG_TYR_ITIM	52	57	PF00017	0.292
LIG_UBA3_1	17	26	PF00899	0.298
LIG_UBA3_1	29	34	PF00899	0.278
MOD_CK2_1	128	134	PF00069	0.303
MOD_Cter_Amidation	9	12	PF01082	0.452
MOD_GSK3_1	129	136	PF00069	0.309
MOD_GSK3_1	37	44	PF00069	0.296
MOD_N-GLC_1	113	118	PF02516	0.331
MOD_NEK2_1	57	62	PF00069	0.299
MOD_NMyristoyl	1	7	PF02799	0.524
MOD_Plk_1	113	119	PF00069	0.431
MOD_Plk_4	113	119	PF00069	0.388
MOD_Plk_4	25	31	PF00069	0.303
MOD_Plk_4	4	10	PF00069	0.321
MOD_SUMO_for_1	99	102	PF00179	0.316
MOD_SUMO_rev_2	50	57	PF00179	0.292
MOD_SUMO_rev_2	92	101	PF00179	0.431
TRG_DiLeu_BaEn_1	13	18	PF01217	0.316
TRG_ENDOCYTIC_2	163	166	PF00928	0.303
TRG_ENDOCYTIC_2	54	57	PF00928	0.298
TRG_ER_diArg_1	144	147	PF00400	0.303
TRG_ER_diLys_1	174	178	PF00400	0.493
TRG_Pf-PMV_PEXEL_1	105	109	PF00026	0.292

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q3	Leptomonas seymouri	51%	94%
A0A0N0P4P7	Leptomonas seymouri	35%	98%
A0A0N0P633	Leptomonas seymouri	77%	97%
A0A0N0P8D4	Leptomonas seymouri	46%	99%
A0A0N0P8G7	Leptomonas seymouri	21%	82%
A0A0N0P8Z3	Leptomonas seymouri	43%	100%
A0A0N1HS40	Leptomonas seymouri	40%	100%
A0A0N1HTN6	Leptomonas seymouri	52%	94%
A0A0N1I3A9	Leptomonas seymouri	45%	99%
A0A0N1I556	Leptomonas seymouri	96%	100%
A0A0N1I6N0	Leptomonas seymouri	42%	100%
A0A0N1IKF2	Leptomonas seymouri	33%	91%
A0A0N1ILN4	Leptomonas seymouri	29%	89%
A0A0N1PD39	Leptomonas seymouri	35%	99%
A0A0S4IQT8	Bodo saltans	42%	95%
A0A0S4IS60	Bodo saltans	52%	100%
A0A0S4J1G8	Bodo saltans	25%	81%
A0A0S4J2X3	Bodo saltans	47%	98%
A0A0S4J3L7	Bodo saltans	36%	99%
A0A0S4J5U8	Bodo saltans	35%	94%
A0A0S4J8H6	Bodo saltans	58%	99%
A0A0S4JF89	Bodo saltans	28%	81%
A0A0S4JK65	Bodo saltans	40%	100%
A0A0S4JQ13	Bodo saltans	39%	91%
A0A0S4KJ70	Bodo saltans	87%	84%
A0A0S4KKS9	Bodo saltans	59%	100%
A0A0S4KLN8	Bodo saltans	25%	74%
A0A1X0NKM5	Trypanosomatidae	40%	96%
A0A1X0NKZ8	Trypanosomatidae	40%	92%
A0A1X0NLB1	Trypanosomatidae	57%	94%
A0A1X0NLP5	Trypanosomatidae	46%	97%
A0A1X0NR74	Trypanosomatidae	31%	86%
A0A1X0NT19	Trypanosomatidae	52%	94%
A0A1X0NVM5	Trypanosomatidae	24%	82%
A0A1X0NZX3	Trypanosomatidae	47%	100%
A0A1X0P0A2	Trypanosomatidae	37%	99%
A0A1X0P0D4	Trypanosomatidae	36%	92%
A0A1X0P1Y5	Trypanosomatidae	40%	97%
A0A1X0P2L5	Trypanosomatidae	32%	92%
A0A1X0P5P0	Trypanosomatidae	86%	98%
A0A1X0P676	Trypanosomatidae	34%	93%
A0A221LG87	Leishmania donovani	33%	91%
A0A3Q8IDS2	Leishmania donovani	35%	98%
A0A3Q8IE68	Leishmania donovani	30%	89%
A0A3Q8IFX9	Leishmania donovani	40%	99%
A0A3Q8IK84	Leishmania donovani	24%	82%
A0A3R7K3A9	Trypanosoma rangeli	30%	86%
A0A3R7KSW8	Trypanosoma rangeli	35%	99%
A0A3R7L2X6	Trypanosoma rangeli	85%	100%
A0A3R7MW79	Trypanosoma rangeli	56%	94%
A0A3R7NC73	Trypanosoma rangeli	52%	94%
A0A3R7NMH3	Trypanosoma rangeli	34%	94%
A0A3R7RGT1	Trypanosoma rangeli	40%	97%
A0A3S5H598	Leishmania donovani	43%	97%
A0A3S5H5A9	Leishmania donovani	50%	94%
A0A3S5IQP0	Trypanosoma rangeli	40%	96%
A0A3S5ISB1	Trypanosoma rangeli	32%	97%
A0A3S7WU76	Leishmania donovani	53%	95%
A0A3S7X4X3	Leishmania donovani	96%	100%
A0A3S7X8N3	Leishmania donovani	41%	96%
A0A3S7XC57	Leishmania donovani	42%	100%
A0A422MYB1	Trypanosoma rangeli	84%	98%
A0A422MYF8	Trypanosoma rangeli	84%	100%
A0A422MZM4	Trypanosoma rangeli	39%	92%
A0A422NNC6	Trypanosoma rangeli	41%	93%
A0A422NRN0	Trypanosoma rangeli	46%	100%
A0A422NW53	Trypanosoma rangeli	40%	96%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	39%	94%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	39%	94%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	40%	94%
A4FV54	Bos taurus	28%	86%
A4H3V3	Leishmania braziliensis	43%	97%
A4H3W8	Leishmania braziliensis	48%	94%
A4H449	Leishmania braziliensis	33%	100%
A4H8R6	Leishmania braziliensis	36%	98%
A4H8V3	Leishmania braziliensis	51%	95%
A4HFK0	Leishmania braziliensis	29%	89%
A4HH98	Leishmania braziliensis	45%	99%
A4HJL1	Leishmania braziliensis	77%	100%
A4HLP5	Leishmania braziliensis	26%	82%
A4HM52	Leishmania braziliensis	41%	96%
A4HQE3	Leishmania braziliensis	41%	100%
A4HS29	Leishmania infantum	42%	97%
A4HS43	Leishmania infantum	50%	94%
A4HSC6	Leishmania infantum	33%	91%
A4HX34	Leishmania infantum	35%	98%
A4HX72	Leishmania infantum	53%	95%
A4I4E4	Leishmania infantum	46%	99%
A4I5R5	Leishmania infantum	40%	99%
A4I784	Leishmania infantum	96%	100%
A4I946	Leishmania infantum	24%	82%
A4IAR4	Leishmania infantum	41%	96%
A4IE34	Leishmania infantum	42%	100%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	35%	94%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	39%	94%
A6NH57	Homo sapiens	44%	99%
A8ISN6	Chlamydomonas reinhardtii	42%	100%
B5FYQ0	Taeniopygia guttata	43%	98%
B6DT76	Bodo saltans	30%	87%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	92%
C9ZQX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	74%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	97%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	94%
C9ZUL0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	86%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	94%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	92%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	94%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	86%	98%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	85%	98%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	96%
D0AA91	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	84%
E9AD53	Leishmania major	30%	89%
E9ADU4	Leishmania major	44%	100%
E9AEJ0	Leishmania major	41%	100%
E9AHE8	Leishmania infantum	30%	89%
E9AHL7	Leishmania infantum	77%	98%
E9AIU0	Leishmania braziliensis	39%	99%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	97%
E9AK30	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%
E9AKA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	91%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	99%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	98%
E9ARC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	95%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9AYX8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	89%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	99%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	98%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9B420	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	82%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	96%
F4IZ82	Arabidopsis thaliana	34%	100%
O00909	Dictyostelium discoideum	72%	98%
O04266	Brassica campestris	35%	92%
O04267	Brassica campestris	34%	91%
O04834	Arabidopsis thaliana	34%	92%
O08697	Rattus norvegicus	52%	97%
O23778	Catharanthus roseus	76%	98%
O42819	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	29%	83%
O45379	Caenorhabditis elegans	46%	97%
O48649	Salix bakko	78%	98%
O48920	Vigna unguiculata	78%	98%
O49841	Arabidopsis thaliana	28%	85%
O88848	Mus musculus	42%	96%
P01123	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	86%
P07560	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	83%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	37%	94%
P0C950	Aspergillus niger	36%	94%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	36%	94%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	77%	98%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	77%	98%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	39%	94%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	39%	94%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	39%	94%
P0CT17	Magnaporthe oryzae (strain Y34)	39%	94%
P0DH91	Arabidopsis thaliana	78%	98%
P10536	Rattus norvegicus	31%	89%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	70%	98%
P11620	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	88%
P16976	Zea mays	32%	86%
P18085	Homo sapiens	71%	99%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	71%	98%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	94%
P22125	Diplobatis ommata	28%	88%
P22127	Diplobatis ommata	28%	89%
P22128	Diplobatis ommata	29%	85%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	73%	99%
P24409	Canis lupus familiaris	28%	89%
P25160	Drosophila melanogaster	58%	99%
P26990	Gallus gallus	66%	100%
P26991	Giardia intestinalis	71%	93%
P28186	Arabidopsis thaliana	27%	82%
P28188	Arabidopsis thaliana	31%	88%
P31584	Volvox carteri	33%	88%
P33723	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	29%	88%
P34139	Dictyostelium discoideum	31%	88%
P34212	Caenorhabditis elegans	49%	100%
P34727	Ajellomyces capsulatus	73%	97%
P35280	Rattus norvegicus	28%	86%
P36397	Arabidopsis thaliana	77%	98%
P36404	Homo sapiens	50%	97%
P36405	Homo sapiens	43%	98%
P36536	Mus musculus	33%	90%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	76%	99%
P36862	Volvox carteri	34%	88%
P37996	Rattus norvegicus	44%	98%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	57%	97%
P38146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	89%
P39110	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	93%
P40392	Oryza sativa subsp. japonica	31%	88%
P40616	Homo sapiens	59%	98%
P40617	Homo sapiens	44%	89%
P40940	Arabidopsis thaliana	57%	98%
P40945	Drosophila melanogaster	74%	99%
P40946	Drosophila melanogaster	65%	100%
P40994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	55%	97%
P49076	Zea mays	78%	98%
P49702	Gallus gallus	72%	99%
P49703	Homo sapiens	41%	89%
P51152	Canis lupus familiaris	23%	86%
P51643	Xenopus laevis	76%	98%
P51644	Xenopus laevis	73%	99%
P51645	Xenopus laevis	64%	100%
P51646	Rattus norvegicus	48%	99%
P51821	Chlamydomonas reinhardtii	78%	98%
P51822	Daucus carota	78%	98%
P51823	Oryza sativa subsp. japonica	78%	98%
P51824	Solanum tuberosum	78%	90%
P52884	Solanum lycopersicum	37%	92%
P55258	Mus musculus	28%	86%
P56559	Homo sapiens	46%	93%
P61006	Homo sapiens	28%	86%
P61007	Canis lupus familiaris	28%	86%
P61026	Homo sapiens	28%	89%
P61027	Mus musculus	28%	89%
P61028	Mus musculus	29%	86%
P61204	Homo sapiens	76%	98%
P61205	Mus musculus	76%	98%
P61206	Rattus norvegicus	76%	98%
P61207	Takifugu rubripes	76%	98%
P61208	Mus musculus	46%	93%
P61209	Drosophila melanogaster	76%	98%
P61210	Locusta migratoria	76%	98%
P61211	Mus musculus	59%	98%
P61212	Rattus norvegicus	59%	98%
P61213	Mus musculus	45%	89%
P61214	Rattus norvegicus	45%	89%
P61750	Mus musculus	72%	99%
P61751	Rattus norvegicus	72%	99%
P62330	Homo sapiens	66%	100%
P62331	Mus musculus	66%	100%
P62332	Rattus norvegicus	66%	100%
P62820	Homo sapiens	28%	87%
P62821	Mus musculus	28%	87%
P62822	Canis lupus familiaris	28%	87%
P70550	Rattus norvegicus	29%	86%
P78976	Hypocrea jecorina	37%	94%
P84077	Homo sapiens	76%	98%
P84078	Mus musculus	76%	98%
P84079	Rattus norvegicus	76%	98%
P84080	Bos taurus	76%	98%
P84081	Bos taurus	78%	98%
P84082	Rattus norvegicus	78%	98%
P84083	Rattus norvegicus	71%	99%
P84084	Mus musculus	71%	99%
P84085	Homo sapiens	71%	99%
P90726	Caenorhabditis briggsae	28%	88%
P91924	Dugesia japonica	76%	97%
Q007T5	Sus scrofa	66%	100%
Q01474	Arabidopsis thaliana	34%	92%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	94%
Q01890	Phytophthora infestans	29%	89%
Q02804	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	90%
Q05737	Zea mays	29%	88%
Q05974	Lymnaea stagnalis	28%	87%
Q06396	Oryza sativa subsp. japonica	78%	98%
Q06849	Drosophila melanogaster	46%	97%
Q06AU7	Sus scrofa	28%	89%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	96%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	38%	94%
Q0IIM2	Bos taurus	42%	96%
Q0P5N6	Homo sapiens	32%	90%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	39%	96%
Q0VC18	Bos taurus	42%	89%
Q10943	Caenorhabditis elegans	75%	98%
Q13795	Homo sapiens	32%	89%
Q15286	Homo sapiens	26%	89%
Q18510	Caenorhabditis elegans	40%	94%
Q19705	Caenorhabditis elegans	41%	97%
Q1MTE5	Danio rerio	45%	98%
Q1ZXA5	Dictyostelium discoideum	36%	96%
Q20758	Caenorhabditis elegans	56%	99%
Q23445	Caenorhabditis elegans	28%	92%
Q25761	Plasmodium falciparum (isolate NF54)	68%	98%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	38%	94%
Q2HJH2	Bos taurus	28%	89%
Q2HJI8	Bos taurus	29%	86%
Q2KI07	Bos taurus	32%	96%
Q2KJ96	Bos taurus	48%	99%
Q2TA37	Bos taurus	50%	97%
Q2TBW6	Bos taurus	44%	98%
Q2YDM1	Bos taurus	59%	98%
Q32LJ2	Bos taurus	32%	89%
Q39433	Beta vulgaris	27%	83%
Q39434	Beta vulgaris	28%	83%
Q39571	Chlamydomonas reinhardtii	31%	88%
Q3SXC5	Mus musculus	43%	93%
Q3SZF2	Bos taurus	73%	99%
Q3T0D7	Bos taurus	33%	90%
Q3T0M9	Bos taurus	45%	89%
Q3T0T7	Bos taurus	32%	90%
Q40193	Lotus japonicus	28%	82%
Q40520	Nicotiana tabacum	28%	80%
Q40522	Nicotiana tabacum	27%	80%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	37%	94%
Q4Q0D7	Leishmania major	42%	100%
Q4Q5Y0	Leishmania major	96%	100%
Q4Q756	Leishmania major	40%	100%
Q4QEJ1	Leishmania major	53%	100%
Q4QEM9	Leishmania major	36%	100%
Q4QJK0	Leishmania major	33%	100%
Q4R4S4	Macaca fascicularis	33%	96%
Q4R5P1	Macaca fascicularis	28%	86%
Q4R5P2	Macaca fascicularis	76%	98%
Q4R8X3	Macaca fascicularis	29%	89%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	39%	94%
Q52NJ2	Sus scrofa	28%	87%
Q52NJ3	Sus scrofa	33%	90%
Q52NJ4	Sus scrofa	44%	98%
Q54GY8	Dictyostelium discoideum	23%	88%
Q54HK2	Dictyostelium discoideum	50%	94%
Q54I24	Dictyostelium discoideum	49%	82%
Q54JJ3	Dictyostelium discoideum	57%	94%
Q54K69	Dictyostelium discoideum	29%	90%
Q54NU2	Dictyostelium discoideum	34%	87%
Q54R04	Dictyostelium discoideum	35%	96%
Q54UF1	Dictyostelium discoideum	48%	97%
Q54V41	Dictyostelium discoideum	59%	95%
Q54V47	Dictyostelium discoideum	60%	95%
Q54Y14	Dictyostelium discoideum	32%	92%
Q54YV7	Dictyostelium discoideum	25%	91%
Q559R0	Dictyostelium discoideum	35%	95%
Q55AD9	Dictyostelium discoideum	50%	97%
Q55EF0	Dictyostelium discoideum	21%	82%
Q55EG6	Dictyostelium discoideum	23%	80%
Q58DI9	Bos taurus	42%	98%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	40%	94%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	94%
Q5BK71	Rattus norvegicus	42%	100%
Q5E9I6	Bos taurus	76%	98%
Q5EA19	Bos taurus	31%	88%
Q5HZY2	Rattus norvegicus	32%	90%
Q5M9P8	Danio rerio	42%	96%
Q5PYH3	Sus scrofa	32%	90%
Q5R4A3	Pongo abelii	28%	86%
Q5R4G5	Pongo abelii	43%	96%
Q5R548	Pongo abelii	33%	90%
Q5R579	Pongo abelii	32%	89%
Q5R5P7	Pongo abelii	76%	98%
Q5R5U1	Pongo abelii	28%	89%
Q5R6E7	Pongo abelii	32%	96%
Q5RCF1	Pongo abelii	71%	99%
Q5RCQ6	Pongo abelii	39%	100%
Q5RE13	Pongo abelii	28%	89%
Q5REC9	Pongo abelii	29%	86%
Q5REU3	Pongo abelii	41%	89%
Q5RFN0	Pongo abelii	33%	87%
Q5U1Y1	Rattus norvegicus	23%	69%
Q5U316	Rattus norvegicus	26%	89%
Q5UQ27	Acanthamoeba polyphaga mimivirus	27%	83%
Q5VLR7	Leishmania donovani	77%	98%
Q5ZHV1	Gallus gallus	26%	78%
Q5ZKQ8	Gallus gallus	32%	96%
Q60Z38	Caenorhabditis briggsae	41%	94%
Q61LA8	Caenorhabditis briggsae	75%	98%
Q627K4	Caenorhabditis briggsae	41%	97%
Q63055	Rattus norvegicus	31%	89%
Q66HA6	Rattus norvegicus	33%	96%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	39%	94%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	38%	94%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	38%	94%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	36%	94%
Q6IMM3	Leishmania major	77%	100%
Q6IQ22	Homo sapiens	23%	73%
Q6NYB7	Rattus norvegicus	28%	87%
Q6NZW8	Danio rerio	33%	96%
Q6P068	Mus musculus	47%	99%
Q6P3A9	Mus musculus	43%	100%
Q6P8C8	Xenopus tropicalis	32%	96%
Q6PHN9	Mus musculus	26%	89%
Q6T311	Homo sapiens	36%	95%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	37%	94%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	75%	98%
Q76NM7	Plasmodium falciparum (isolate 3D7)	25%	86%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	68%	98%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	77%	96%
Q7T3A4	Danio rerio	28%	89%
Q80ZU0	Mus musculus	48%	99%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	38%	94%
Q8BGR6	Mus musculus	32%	87%
Q8BSL7	Mus musculus	78%	98%
Q8BXL7	Mus musculus	31%	89%
Q8MQT8	Giardia intestinalis	31%	93%
Q8MXS1	Caenorhabditis elegans	28%	88%
Q8N4G2	Homo sapiens	43%	93%
Q8N8L6	Homo sapiens	36%	73%
Q8QHI3	Xenopus laevis	44%	98%
Q8SQH8	Encephalitozoon cuniculi (strain GB-M1)	42%	86%
Q8SS09	Encephalitozoon cuniculi (strain GB-M1)	35%	81%
Q8VEH3	Mus musculus	32%	96%
Q8VY57	Arabidopsis thaliana	34%	97%
Q8W4C8	Arabidopsis thaliana	34%	97%
Q92928	Homo sapiens	26%	89%
Q92930	Homo sapiens	29%	86%
Q93Y31	Arabidopsis thaliana	33%	97%
Q94148	Caenorhabditis elegans	30%	89%
Q94231	Caenorhabditis elegans	56%	99%
Q94650	Plasmodium falciparum	68%	98%
Q96283	Arabidopsis thaliana	29%	82%
Q96361	Brassica rapa subsp. pekinensis	57%	98%
Q969Q4	Homo sapiens	41%	91%
Q96AX2	Homo sapiens	24%	80%
Q96BM9	Homo sapiens	32%	96%
Q96KC2	Homo sapiens	50%	99%
Q99P58	Mus musculus	22%	82%
Q99PE9	Mus musculus	41%	89%
Q9CQC9	Mus musculus	32%	90%
Q9CQW2	Mus musculus	33%	96%
Q9D0J4	Mus musculus	52%	97%
Q9D1G1	Mus musculus	31%	89%
Q9D4P0	Mus musculus	50%	99%
Q9DD03	Mus musculus	28%	88%
Q9FIF9	Arabidopsis thaliana	29%	82%
Q9FJN8	Arabidopsis thaliana	28%	79%
Q9FPJ4	Arabidopsis thaliana	29%	88%
Q9H0F7	Homo sapiens	43%	96%
Q9H0U4	Homo sapiens	28%	89%
Q9LNW1	Arabidopsis thaliana	28%	83%
Q9LQC8	Arabidopsis thaliana	78%	98%
Q9N6B0	Leishmania donovani	46%	99%
Q9NR31	Homo sapiens	33%	90%
Q9NVJ2	Homo sapiens	33%	96%
Q9NXU5	Homo sapiens	33%	87%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	36%	94%
Q9QVY3	Cricetulus griseus	32%	90%
Q9QXJ4	Mus musculus	37%	73%
Q9SEH3	Arabidopsis thaliana	29%	88%
Q9SHU5	Arabidopsis thaliana	64%	87%
Q9SMQ6	Arabidopsis thaliana	26%	79%
Q9U0T6	Leishmania major	50%	100%
Q9VHV5	Drosophila melanogaster	32%	96%
Q9WUL7	Mus musculus	44%	98%
Q9XZX2	Leishmania major	42%	100%
Q9Y689	Homo sapiens	48%	99%
Q9Y6B6	Homo sapiens	32%	90%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	60%	97%
Q9ZPX1	Arabidopsis thaliana	44%	96%
Q9ZRE2	Arabidopsis thaliana	28%	87%
V5B891	Trypanosoma cruzi	51%	94%
V5BBM5	Trypanosoma cruzi	25%	86%
V5DJR8	Trypanosoma cruzi	40%	96%