AP2/ERF domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJM9_LEIBR

TriTrypDb:

LbrM.31.2740 , LBRM2903_310037100

Length:

203

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJM9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJM9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	37	41	PF00656	0.458
CLV_PCSK_KEX2_1	111	113	PF00082	0.572
CLV_PCSK_KEX2_1	145	147	PF00082	0.582
CLV_PCSK_PC1ET2_1	111	113	PF00082	0.572
CLV_PCSK_PC1ET2_1	145	147	PF00082	0.582
CLV_PCSK_SKI1_1	192	196	PF00082	0.643
CLV_PCSK_SKI1_1	61	65	PF00082	0.581
DEG_Nend_UBRbox_2	1	3	PF02207	0.576
DOC_CYCLIN_yClb5_NLxxxL_5	173	182	PF00134	0.516
DOC_MAPK_gen_1	110	118	PF00069	0.494
DOC_MAPK_MEF2A_6	135	143	PF00069	0.461
DOC_USP7_UBL2_3	60	64	PF12436	0.540
LIG_FHA_1	111	117	PF00498	0.641
LIG_FHA_1	142	148	PF00498	0.526
LIG_FHA_1	151	157	PF00498	0.548
LIG_FHA_1	158	164	PF00498	0.522
LIG_FHA_1	73	79	PF00498	0.545
LIG_FHA_2	32	38	PF00498	0.541
LIG_LIR_Gen_1	65	74	PF02991	0.638
LIG_LIR_Nem_3	172	178	PF02991	0.460
LIG_NRP_CendR_1	200	203	PF00754	0.522
LIG_Pex14_1	114	118	PF04695	0.594
LIG_SH2_CRK	175	179	PF00017	0.498
LIG_SH2_STAP1	100	104	PF00017	0.721
LIG_SH2_STAT5	102	105	PF00017	0.596
LIG_SUMO_SIM_anti_2	162	167	PF11976	0.467
LIG_SUMO_SIM_par_1	157	164	PF11976	0.484
LIG_SUMO_SIM_par_1	20	26	PF11976	0.596
LIG_TYR_ITIM	173	178	PF00017	0.530
LIG_UBA3_1	130	135	PF00899	0.570
MOD_CK1_1	23	29	PF00069	0.489
MOD_GlcNHglycan	91	94	PF01048	0.578
MOD_GSK3_1	194	201	PF00069	0.651
MOD_GSK3_1	3	10	PF00069	0.538
MOD_GSK3_1	94	101	PF00069	0.655
MOD_NEK2_1	139	144	PF00069	0.632
MOD_NEK2_1	194	199	PF00069	0.509
MOD_NEK2_2	100	105	PF00069	0.578
MOD_NEK2_2	20	25	PF00069	0.457
MOD_NEK2_2	72	77	PF00069	0.600
MOD_PIKK_1	23	29	PF00454	0.539
MOD_PIKK_1	3	9	PF00454	0.618
MOD_PKA_1	110	116	PF00069	0.560
MOD_Plk_2-3	157	163	PF00069	0.553
MOD_SUMO_rev_2	2	6	PF00179	0.475
TRG_ENDOCYTIC_2	121	124	PF00928	0.480
TRG_ENDOCYTIC_2	175	178	PF00928	0.546
TRG_ENDOCYTIC_2	44	47	PF00928	0.624
TRG_NLS_MonoExtN_4	107	114	PF00514	0.517

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I730	Leptomonas seymouri	43%	100%
A0A0N1I8Q6	Leptomonas seymouri	24%	89%
A0A3Q8IF19	Leishmania donovani	23%	93%
A0A3Q8IKA6	Leishmania donovani	57%	100%
A4HJM8	Leishmania braziliensis	23%	100%
A4I750	Leishmania infantum	23%	93%
A4I751	Leishmania infantum	57%	100%
E9B245	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%
Q4Q616	Leishmania major	56%	100%
Q4Q617	Leishmania major	23%	100%