Pectinesterase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Pectinesterase

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJM7_LEIBR

TriTrypDb:

LbrM.31.2720 , LBRM2903_310036900

Length:

243

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJM7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJM7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	208	210	PF00675	0.582
CLV_PCSK_FUR_1	222	226	PF00082	0.310
CLV_PCSK_KEX2_1	208	210	PF00082	0.512
CLV_PCSK_KEX2_1	224	226	PF00082	0.428
CLV_PCSK_PC1ET2_1	224	226	PF00082	0.428
CLV_PCSK_SKI1_1	209	213	PF00082	0.515
CLV_PCSK_SKI1_1	46	50	PF00082	0.416
CLV_PCSK_SKI1_1	99	103	PF00082	0.479
DEG_Nend_UBRbox_2	1	3	PF02207	0.550
DEG_SPOP_SBC_1	174	178	PF00917	0.425
DOC_CKS1_1	14	19	PF01111	0.597
DOC_MAPK_DCC_7	166	174	PF00069	0.488
DOC_MAPK_gen_1	123	130	PF00069	0.370
DOC_MAPK_gen_1	97	104	PF00069	0.475
DOC_MAPK_MEF2A_6	123	130	PF00069	0.370
DOC_MAPK_MEF2A_6	97	104	PF00069	0.498
DOC_MAPK_NFAT4_5	97	105	PF00069	0.499
DOC_USP7_MATH_1	114	118	PF00917	0.580
DOC_USP7_UBL2_3	166	170	PF12436	0.505
DOC_WW_Pin1_4	13	18	PF00397	0.643
DOC_WW_Pin1_4	147	152	PF00397	0.492
DOC_WW_Pin1_4	3	8	PF00397	0.735
LIG_14-3-3_CanoR_1	233	238	PF00244	0.456
LIG_14-3-3_CanoR_1	40	50	PF00244	0.378
LIG_EH1_1	190	198	PF00400	0.256
LIG_FHA_1	178	184	PF00498	0.442
LIG_FHA_1	43	49	PF00498	0.425
LIG_FHA_1	54	60	PF00498	0.435
LIG_FHA_2	103	109	PF00498	0.391
LIG_FHA_2	184	190	PF00498	0.419
LIG_FHA_2	227	233	PF00498	0.470
LIG_LIR_Apic_2	11	17	PF02991	0.522
LIG_LIR_Gen_1	179	188	PF02991	0.417
LIG_LIR_Gen_1	90	101	PF02991	0.493
LIG_LIR_Nem_3	179	185	PF02991	0.330
LIG_LIR_Nem_3	90	96	PF02991	0.500
LIG_PCNA_yPIPBox_3	115	125	PF02747	0.406
LIG_PDZ_Class_3	238	243	PF00595	0.745
LIG_Pex14_1	181	185	PF04695	0.386
LIG_SH2_CRK	14	18	PF00017	0.526
LIG_SH2_NCK_1	14	18	PF00017	0.526
LIG_SH2_STAP1	191	195	PF00017	0.424
LIG_SH2_STAT5	121	124	PF00017	0.400
LIG_SH2_STAT5	14	17	PF00017	0.527
LIG_SH3_1	14	20	PF00018	0.522
LIG_SH3_3	14	20	PF00018	0.617
LIG_SUMO_SIM_anti_2	28	34	PF11976	0.309
LIG_SUMO_SIM_par_1	170	180	PF11976	0.408
LIG_SUMO_SIM_par_1	44	53	PF11976	0.431
LIG_SUMO_SIM_par_1	55	60	PF11976	0.439
LIG_UBA3_1	196	204	PF00899	0.501
LIG_WRC_WIRS_1	182	187	PF05994	0.261
MOD_CDK_SPK_2	147	152	PF00069	0.487
MOD_CK1_1	12	18	PF00069	0.546
MOD_CK1_1	160	166	PF00069	0.553
MOD_CK1_1	173	179	PF00069	0.644
MOD_CK1_1	184	190	PF00069	0.454
MOD_CK1_1	236	242	PF00069	0.497
MOD_CK1_1	5	11	PF00069	0.528
MOD_CK2_1	102	108	PF00069	0.558
MOD_CK2_1	183	189	PF00069	0.417
MOD_CK2_1	226	232	PF00069	0.412
MOD_GlcNHglycan	11	14	PF01048	0.514
MOD_GlcNHglycan	130	133	PF01048	0.574
MOD_GlcNHglycan	154	157	PF01048	0.733
MOD_GlcNHglycan	163	166	PF01048	0.699
MOD_GlcNHglycan	226	229	PF01048	0.613
MOD_GSK3_1	135	142	PF00069	0.598
MOD_GSK3_1	147	154	PF00069	0.618
MOD_GSK3_1	157	164	PF00069	0.547
MOD_GSK3_1	170	177	PF00069	0.571
MOD_GSK3_1	183	190	PF00069	0.408
MOD_GSK3_1	3	10	PF00069	0.512
MOD_GSK3_1	42	49	PF00069	0.417
MOD_GSK3_1	53	60	PF00069	0.456
MOD_N-GLC_1	114	119	PF02516	0.428
MOD_N-GLC_1	158	163	PF02516	0.559
MOD_N-GLC_1	8	13	PF02516	0.537
MOD_NEK2_1	102	107	PF00069	0.503
MOD_NEK2_1	130	135	PF00069	0.529
MOD_PIKK_1	15	21	PF00454	0.651
MOD_PIKK_1	25	31	PF00454	0.410
MOD_PIKK_1	57	63	PF00454	0.359
MOD_PK_1	170	176	PF00069	0.666
MOD_PKA_1	224	230	PF00069	0.343
MOD_PKA_2	224	230	PF00069	0.343
MOD_PKA_2	41	47	PF00069	0.502
MOD_PKB_1	40	48	PF00069	0.416
MOD_Plk_1	107	113	PF00069	0.433
MOD_Plk_1	114	120	PF00069	0.476
MOD_Plk_4	177	183	PF00069	0.514
MOD_ProDKin_1	13	19	PF00069	0.642
MOD_ProDKin_1	147	153	PF00069	0.496
MOD_ProDKin_1	3	9	PF00069	0.737
TRG_ER_diArg_1	40	43	PF00400	0.533
TRG_Pf-PMV_PEXEL_1	46	51	PF00026	0.452
TRG_Pf-PMV_PEXEL_1	71	76	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8Q6	Leptomonas seymouri	38%	100%
A0A0N1ILD5	Leptomonas seymouri	27%	86%
A0A0N1PCW5	Leptomonas seymouri	29%	100%
A0A3Q8IF19	Leishmania donovani	41%	100%
A0A3S5H7Q5	Leishmania donovani	55%	100%
A4HJM8	Leishmania braziliensis	37%	100%
A4I749	Leishmania infantum	55%	100%
A4I750	Leishmania infantum	41%	100%
E9B242	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B243	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	100%
E9B244	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
Q4Q617	Leishmania major	41%	100%
Q4Q618	Leishmania major	51%	70%