Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJM6_LEIBR

TriTrypDb:

LbrM.31.2710 , LBRM2903_310036700

Length:

225

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJM6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJM6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	197	201	PF00656	0.589
CLV_PCSK_SKI1_1	188	192	PF00082	0.565
CLV_PCSK_SKI1_1	44	48	PF00082	0.522
CLV_PCSK_SKI1_1	89	93	PF00082	0.503
DOC_MAPK_MEF2A_6	13	22	PF00069	0.494
DOC_PP2B_LxvP_1	171	174	PF13499	0.444
DOC_USP7_MATH_1	207	211	PF00917	0.717
DOC_USP7_MATH_1	50	54	PF00917	0.478
DOC_USP7_MATH_1	91	95	PF00917	0.582
DOC_USP7_UBL2_3	123	127	PF12436	0.462
DOC_WW_Pin1_4	136	141	PF00397	0.514
DOC_WW_Pin1_4	14	19	PF00397	0.727
DOC_WW_Pin1_4	144	149	PF00397	0.489
LIG_14-3-3_CanoR_1	203	207	PF00244	0.611
LIG_14-3-3_CanoR_1	44	49	PF00244	0.453
LIG_CaMK_CASK_1	182	188	PF00069	0.642
LIG_Clathr_ClatBox_1	221	225	PF01394	0.439
LIG_FHA_1	109	115	PF00498	0.522
LIG_FHA_1	41	47	PF00498	0.551
LIG_FHA_1	98	104	PF00498	0.555
LIG_FHA_2	189	195	PF00498	0.582
LIG_FHA_2	203	209	PF00498	0.574
LIG_LIR_Apic_2	12	18	PF02991	0.500
LIG_LIR_Nem_3	78	83	PF02991	0.685
LIG_PCNA_yPIPBox_3	110	119	PF02747	0.442
LIG_SH2_STAP1	180	184	PF00017	0.502
LIG_SH2_STAT5	56	59	PF00017	0.603
LIG_SUMO_SIM_anti_2	72	78	PF11976	0.458
LIG_SUMO_SIM_par_1	43	49	PF11976	0.524
LIG_UBA3_1	54	62	PF00899	0.449
MOD_CDK_SPxxK_3	14	21	PF00069	0.493
MOD_CK1_1	113	119	PF00069	0.594
MOD_CK1_1	149	155	PF00069	0.671
MOD_CK1_1	162	168	PF00069	0.519
MOD_CK2_1	202	208	PF00069	0.703
MOD_GlcNHglycan	140	143	PF01048	0.745
MOD_GlcNHglycan	167	171	PF01048	0.502
MOD_GSK3_1	138	145	PF00069	0.684
MOD_GSK3_1	162	169	PF00069	0.635
MOD_GSK3_1	198	205	PF00069	0.546
MOD_GSK3_1	40	47	PF00069	0.554
MOD_LATS_1	42	48	PF00433	0.611
MOD_N-GLC_1	159	164	PF02516	0.578
MOD_NEK2_1	198	203	PF00069	0.444
MOD_NEK2_1	55	60	PF00069	0.471
MOD_NEK2_2	207	212	PF00069	0.462
MOD_PIKK_1	108	114	PF00454	0.527
MOD_PKA_2	202	208	PF00069	0.651
MOD_Plk_1	159	165	PF00069	0.663
MOD_Plk_1	207	213	PF00069	0.554
MOD_Plk_4	110	116	PF00069	0.625
MOD_Plk_4	50	56	PF00069	0.501
MOD_ProDKin_1	136	142	PF00069	0.514
MOD_ProDKin_1	14	20	PF00069	0.726
MOD_ProDKin_1	144	150	PF00069	0.486
TRG_DiLeu_BaEn_2	23	29	PF01217	0.464
TRG_Pf-PMV_PEXEL_1	44	49	PF00026	0.553

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6W0	Leptomonas seymouri	28%	100%
A0A0N1ILD5	Leptomonas seymouri	37%	80%
A0A0N1PCW5	Leptomonas seymouri	29%	100%
A0A3S7X4T4	Leishmania donovani	51%	99%
A4I748	Leishmania infantum	51%	99%
E9B242	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	99%
Q4Q619	Leishmania major	48%	100%