Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJM5_LEIBR

TriTrypDb:

LbrM.31.2700 , LBRM2903_310036600

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJM5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJM5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	163	165	PF00675	0.444
CLV_NRD_NRD_1	91	93	PF00675	0.548
CLV_PCSK_KEX2_1	163	165	PF00082	0.444
CLV_PCSK_KEX2_1	43	45	PF00082	0.511
CLV_PCSK_KEX2_1	91	93	PF00082	0.698
CLV_PCSK_PC1ET2_1	43	45	PF00082	0.511
DEG_SPOP_SBC_1	122	126	PF00917	0.647
DEG_SPOP_SBC_1	150	154	PF00917	0.531
DOC_CYCLIN_yCln2_LP_2	75	81	PF00134	0.654
DOC_MAPK_DCC_7	73	81	PF00069	0.503
DOC_MAPK_gen_1	43	50	PF00069	0.507
DOC_MAPK_MEF2A_6	43	50	PF00069	0.601
DOC_USP7_MATH_1	113	117	PF00917	0.619
DOC_USP7_MATH_1	122	126	PF00917	0.749
DOC_USP7_MATH_1	150	154	PF00917	0.719
DOC_USP7_MATH_1	19	23	PF00917	0.564
DOC_USP7_MATH_1	49	53	PF00917	0.675
DOC_WW_Pin1_4	133	138	PF00397	0.597
DOC_WW_Pin1_4	67	72	PF00397	0.614
LIG_14-3-3_CanoR_1	21	28	PF00244	0.542
LIG_14-3-3_CanoR_1	67	71	PF00244	0.646
LIG_BIR_II_1	1	5	PF00653	0.698
LIG_FHA_1	100	106	PF00498	0.518
LIG_FHA_1	122	128	PF00498	0.596
LIG_LIR_Apic_2	65	71	PF02991	0.538
LIG_PDZ_Class_2	195	200	PF00595	0.572
LIG_Pex14_2	108	112	PF04695	0.552
LIG_SH2_CRK	68	72	PF00017	0.507
LIG_SH2_NCK_1	68	72	PF00017	0.507
LIG_SH2_STAT5	168	171	PF00017	0.524
LIG_SH2_STAT5	68	71	PF00017	0.512
LIG_SH3_2	39	44	PF14604	0.506
LIG_SH3_3	33	39	PF00018	0.682
LIG_WRC_WIRS_1	105	110	PF05994	0.564
LIG_WW_3	70	74	PF00397	0.644
MOD_CDC14_SPxK_1	70	73	PF00782	0.642
MOD_CDK_SPxK_1	67	73	PF00069	0.659
MOD_CK1_1	104	110	PF00069	0.636
MOD_CK1_1	121	127	PF00069	0.743
MOD_CK1_1	132	138	PF00069	0.651
MOD_CK1_1	152	158	PF00069	0.551
MOD_CK1_1	52	58	PF00069	0.720
MOD_CK1_1	66	72	PF00069	0.569
MOD_CK1_1	84	90	PF00069	0.580
MOD_GlcNHglycan	120	123	PF01048	0.773
MOD_GSK3_1	114	121	PF00069	0.636
MOD_GSK3_1	129	136	PF00069	0.625
MOD_GSK3_1	151	158	PF00069	0.569
MOD_GSK3_1	48	55	PF00069	0.709
MOD_GSK3_1	6	13	PF00069	0.682
MOD_GSK3_1	62	69	PF00069	0.628
MOD_GSK3_1	83	90	PF00069	0.529
MOD_NEK2_1	10	15	PF00069	0.727
MOD_NEK2_1	131	136	PF00069	0.534
MOD_NEK2_1	63	68	PF00069	0.599
MOD_NEK2_1	81	86	PF00069	0.475
MOD_NEK2_1	99	104	PF00069	0.673
MOD_NEK2_2	49	54	PF00069	0.610
MOD_PK_1	156	162	PF00069	0.468
MOD_PKA_2	20	26	PF00069	0.547
MOD_PKA_2	66	72	PF00069	0.720
MOD_PKA_2	90	96	PF00069	0.541
MOD_Plk_1	113	119	PF00069	0.630
MOD_Plk_1	26	32	PF00069	0.613
MOD_Plk_4	101	107	PF00069	0.640
MOD_ProDKin_1	133	139	PF00069	0.596
MOD_ProDKin_1	67	73	PF00069	0.612
MOD_SUMO_rev_2	171	179	PF00179	0.537
TRG_DiLeu_BaEn_1	101	106	PF01217	0.641
TRG_ER_diArg_1	162	164	PF00400	0.453

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4V8	Leishmania donovani	64%	99%
A4I747	Leishmania infantum	63%	99%
E9B241	Leishmania mexicana (strain MHOM/GT/2001/U1103)	62%	99%