LeishMANIAdb
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Putative aminopeptidase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:
Putative aminopeptidase
Gene product:
metallo-peptidase, Clan MA(E), Family M1
Species:
Leishmania braziliensis
UniProt:
A4HJL6_LEIBR
TriTrypDb:
LbrM.31.2610 , LBRM2903_310034700
Length:
118

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJL6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJL6

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 2
GO:0004177 aminopeptidase activity 5 2
GO:0008233 peptidase activity 3 2
GO:0008238 exopeptidase activity 4 2
GO:0016787 hydrolase activity 2 2
GO:0140096 catalytic activity, acting on a protein 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 1 3 PF00675 0.824
CLV_NRD_NRD_1 93 95 PF00675 0.746
CLV_PCSK_KEX2_1 93 95 PF00082 0.746
CLV_PCSK_SKI1_1 108 112 PF00082 0.665
CLV_PCSK_SKI1_1 63 67 PF00082 0.627
CLV_Separin_Metazoa 90 94 PF03568 0.742
DEG_APCC_DBOX_1 107 115 PF00400 0.662
DEG_Nend_UBRbox_1 1 4 PF02207 0.821
DEG_SPOP_SBC_1 19 23 PF00917 0.819
DOC_MAPK_gen_1 93 101 PF00069 0.753
DOC_PP4_FxxP_1 14 17 PF00568 0.831
DOC_USP7_MATH_1 17 21 PF00917 0.823
DOC_WW_Pin1_4 13 18 PF00397 0.831
DOC_WW_Pin1_4 99 104 PF00397 0.740
LIG_BRCT_BRCA1_1 10 14 PF00533 0.835
LIG_FHA_1 21 27 PF00498 0.821
LIG_LIR_Apic_2 11 17 PF02991 0.831
LIG_LIR_Gen_1 58 68 PF02991 0.635
LIG_LIR_Nem_3 58 64 PF02991 0.641
LIG_NRBOX 67 73 PF00104 0.636
LIG_PDZ_Class_1 113 118 PF00595 0.664
LIG_SH2_SRC 45 48 PF00017 0.685
LIG_SH2_STAT5 104 107 PF00017 0.698
LIG_SH3_3 73 79 PF00018 0.683
MOD_CK1_1 18 24 PF00069 0.642
MOD_CK1_1 8 14 PF00069 0.829
MOD_CK2_1 103 109 PF00069 0.699
MOD_GlcNHglycan 49 52 PF01048 0.666
MOD_GlcNHglycan 7 10 PF01048 0.820
MOD_GSK3_1 13 20 PF00069 0.830
MOD_GSK3_1 27 34 PF00069 0.551
MOD_GSK3_1 99 106 PF00069 0.727
MOD_ProDKin_1 13 19 PF00069 0.831
MOD_ProDKin_1 99 105 PF00069 0.733
TRG_ER_diArg_1 92 94 PF00400 0.755
TRG_NLS_MonoExtC_3 1 7 PF00514 0.809

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS