LeishMANIAdb
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Non-specific serine/threonine protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Non-specific serine/threonine protein kinase
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4HJJ6_LEIBR
TriTrypDb:
LbrM.31.2400 , LBRM2903_310033500 *
Length:
1020

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJJ6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJJ6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 340 344 PF00656 0.852
CLV_C14_Caspase3-7 424 428 PF00656 0.597
CLV_C14_Caspase3-7 941 945 PF00656 0.665
CLV_C14_Caspase3-7 977 981 PF00656 0.586
CLV_NRD_NRD_1 17 19 PF00675 0.780
CLV_NRD_NRD_1 171 173 PF00675 0.767
CLV_NRD_NRD_1 214 216 PF00675 0.697
CLV_NRD_NRD_1 237 239 PF00675 0.792
CLV_NRD_NRD_1 3 5 PF00675 0.656
CLV_NRD_NRD_1 359 361 PF00675 0.864
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IK75 Leishmania donovani 55% 97%
A4I6Z3 Leishmania infantum 55% 97%
E9B214 Leishmania mexicana (strain MHOM/GT/2001/U1103) 53% 98%
Q4Q647 Leishmania major 54% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS