Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

tubercidin resistance protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HJI3_LEIBR

TriTrypDb:

LbrM.31.2270 , LBRM2903_310031000

Length:

612

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6
GO:0005783	endoplasmic reticulum	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A4HJI3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJI3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	359	363	PF00656	0.733
CLV_C14_Caspase3-7	418	422	PF00656	0.806
CLV_NRD_NRD_1	482	484	PF00675	0.644
CLV_PCSK_KEX2_1	482	484	PF00082	0.644
CLV_PCSK_SKI1_1	12	16	PF00082	0.625
CLV_PCSK_SKI1_1	180	184	PF00082	0.468
CLV_PCSK_SKI1_1	221	225	PF00082	0.387
CLV_PCSK_SKI1_1	560	564	PF00082	0.461
CLV_Separin_Metazoa	43	47	PF03568	0.684
DEG_Nend_UBRbox_2	1	3	PF02207	0.819
DEG_SCF_FBW7_1	143	149	PF00400	0.680
DEG_SCF_FBW7_1	309	316	PF00400	0.700
DEG_SCF_FBW7_1	319	325	PF00400	0.747
DEG_SPOP_SBC_1	313	317	PF00917	0.857
DOC_CKS1_1	143	148	PF01111	0.860
DOC_CKS1_1	319	324	PF01111	0.696
DOC_CKS1_1	546	551	PF01111	0.849
DOC_PP2B_LxvP_1	490	493	PF13499	0.685
DOC_PP4_FxxP_1	31	34	PF00568	0.673
DOC_PP4_FxxP_1	581	584	PF00568	0.785
DOC_USP7_MATH_1	151	155	PF00917	0.676
DOC_USP7_MATH_1	173	177	PF00917	0.777
DOC_USP7_MATH_1	199	203	PF00917	0.690
DOC_USP7_MATH_1	313	317	PF00917	0.864
DOC_USP7_MATH_1	326	330	PF00917	0.710
DOC_USP7_MATH_1	38	42	PF00917	0.684
DOC_USP7_MATH_1	486	490	PF00917	0.669
DOC_USP7_MATH_1	513	517	PF00917	0.673
DOC_USP7_MATH_1	528	532	PF00917	0.620
DOC_USP7_MATH_1	58	62	PF00917	0.633
DOC_USP7_MATH_1	595	599	PF00917	0.530
DOC_USP7_MATH_1	7	11	PF00917	0.666
DOC_USP7_MATH_1	81	85	PF00917	0.827
DOC_WW_Pin1_4	142	147	PF00397	0.780
DOC_WW_Pin1_4	29	34	PF00397	0.855
DOC_WW_Pin1_4	309	314	PF00397	0.832
DOC_WW_Pin1_4	315	320	PF00397	0.808
DOC_WW_Pin1_4	322	327	PF00397	0.719
DOC_WW_Pin1_4	371	376	PF00397	0.806
DOC_WW_Pin1_4	377	382	PF00397	0.857
DOC_WW_Pin1_4	439	444	PF00397	0.784
DOC_WW_Pin1_4	458	463	PF00397	0.686
DOC_WW_Pin1_4	466	471	PF00397	0.831
DOC_WW_Pin1_4	500	505	PF00397	0.809
DOC_WW_Pin1_4	516	521	PF00397	0.656
DOC_WW_Pin1_4	52	57	PF00397	0.690
DOC_WW_Pin1_4	545	550	PF00397	0.850
LIG_14-3-3_CanoR_1	12	18	PF00244	0.671
LIG_14-3-3_CanoR_1	147	151	PF00244	0.790
LIG_14-3-3_CanoR_1	190	195	PF00244	0.662
LIG_14-3-3_CanoR_1	204	213	PF00244	0.632
LIG_14-3-3_CanoR_1	230	240	PF00244	0.784
LIG_14-3-3_CanoR_1	275	284	PF00244	0.684
LIG_14-3-3_CanoR_1	298	303	PF00244	0.675
LIG_14-3-3_CanoR_1	46	51	PF00244	0.696
LIG_14-3-3_CanoR_1	468	477	PF00244	0.702
LIG_14-3-3_CanoR_1	482	486	PF00244	0.726
LIG_14-3-3_CanoR_1	487	491	PF00244	0.685
LIG_14-3-3_CanoR_1	536	545	PF00244	0.658
LIG_BRCT_BRCA1_1	347	351	PF00533	0.692
LIG_CtBP_PxDLS_1	71	75	PF00389	0.669
LIG_deltaCOP1_diTrp_1	228	236	PF00928	0.766
LIG_EVH1_2	504	508	PF00568	0.657
LIG_FHA_1	16	22	PF00498	0.639
LIG_FHA_1	222	228	PF00498	0.581
LIG_FHA_1	281	287	PF00498	0.683
LIG_FHA_1	319	325	PF00498	0.875
LIG_FHA_1	9	15	PF00498	0.669
LIG_FHA_2	101	107	PF00498	0.663
LIG_FHA_2	156	162	PF00498	0.674
LIG_FHA_2	220	226	PF00498	0.693
LIG_FHA_2	246	252	PF00498	0.673
LIG_FHA_2	255	261	PF00498	0.644
LIG_FHA_2	323	329	PF00498	0.875
LIG_FHA_2	416	422	PF00498	0.861
LIG_FHA_2	452	458	PF00498	0.797
LIG_LIR_Apic_2	403	407	PF02991	0.666
LIG_LIR_Apic_2	515	520	PF02991	0.775
LIG_LIR_Nem_3	575	581	PF02991	0.773
LIG_LIR_Nem_3	92	97	PF02991	0.819
LIG_NRBOX	222	228	PF00104	0.762
LIG_REV1ctd_RIR_1	362	372	PF16727	0.849
LIG_SH2_CRK	94	98	PF00017	0.826
LIG_SH2_GRB2like	404	407	PF00017	0.668
LIG_SH2_SRC	404	407	PF00017	0.668
LIG_SH3_3	193	199	PF00018	0.662
LIG_SH3_3	264	270	PF00018	0.672
LIG_SH3_3	316	322	PF00018	0.693
LIG_SH3_3	372	378	PF00018	0.835
LIG_SH3_3	409	415	PF00018	0.669
LIG_SH3_3	440	446	PF00018	0.684
LIG_SH3_3	45	51	PF00018	0.707
LIG_SH3_3	546	552	PF00018	0.849
LIG_SUMO_SIM_anti_2	598	604	PF11976	0.375
LIG_SUMO_SIM_par_1	496	503	PF11976	0.761
LIG_TRAF2_1	33	36	PF00917	0.674
LIG_WW_3	295	299	PF00397	0.659
LIG_WW_3	43	47	PF00397	0.684
MOD_CDK_SPK_2	142	147	PF00069	0.806
MOD_CDK_SPK_2	516	521	PF00069	0.664
MOD_CDK_SPK_2	545	550	PF00069	0.850
MOD_CK1_1	16	22	PF00069	0.782
MOD_CK1_1	175	181	PF00069	0.668
MOD_CK1_1	317	323	PF00069	0.857
MOD_CK1_1	345	351	PF00069	0.806
MOD_CK1_1	442	448	PF00069	0.681
MOD_CK1_1	461	467	PF00069	0.751
MOD_CK1_1	469	475	PF00069	0.820
MOD_CK1_1	516	522	PF00069	0.768
MOD_CK1_1	57	63	PF00069	0.851
MOD_CK1_1	84	90	PF00069	0.819
MOD_CK2_1	155	161	PF00069	0.676
MOD_CK2_1	219	225	PF00069	0.669
MOD_CK2_1	322	328	PF00069	0.875
MOD_CK2_1	353	359	PF00069	0.856
MOD_CK2_1	451	457	PF00069	0.796
MOD_CK2_1	84	90	PF00069	0.702
MOD_DYRK1A_RPxSP_1	54	58	PF00069	0.687
MOD_GlcNHglycan	175	178	PF01048	0.611
MOD_GlcNHglycan	201	204	PF01048	0.551
MOD_GlcNHglycan	233	236	PF01048	0.578
MOD_GlcNHglycan	433	436	PF01048	0.644
MOD_GlcNHglycan	437	440	PF01048	0.595
MOD_GlcNHglycan	597	600	PF01048	0.530
MOD_GlcNHglycan	62	65	PF01048	0.603
MOD_GlcNHglycan	74	77	PF01048	0.467
MOD_GSK3_1	142	149	PF00069	0.679
MOD_GSK3_1	151	158	PF00069	0.656
MOD_GSK3_1	169	176	PF00069	0.637
MOD_GSK3_1	186	193	PF00069	0.770
MOD_GSK3_1	276	283	PF00069	0.729
MOD_GSK3_1	309	316	PF00069	0.713
MOD_GSK3_1	318	325	PF00069	0.756
MOD_GSK3_1	345	352	PF00069	0.796
MOD_GSK3_1	367	374	PF00069	0.817
MOD_GSK3_1	431	438	PF00069	0.686
MOD_GSK3_1	441	448	PF00069	0.824
MOD_GSK3_1	457	464	PF00069	0.666
MOD_GSK3_1	481	488	PF00069	0.673
MOD_GSK3_1	536	543	PF00069	0.705
MOD_GSK3_1	54	61	PF00069	0.732
MOD_GSK3_1	8	15	PF00069	0.766
MOD_GSK3_1	80	87	PF00069	0.824
MOD_GSK3_1	89	96	PF00069	0.706
MOD_LATS_1	210	216	PF00433	0.654
MOD_N-GLC_1	112	117	PF02516	0.473
MOD_N-GLC_1	371	376	PF02516	0.480
MOD_N-GLC_1	7	12	PF02516	0.551
MOD_NEK2_1	13	18	PF00069	0.669
MOD_NEK2_1	150	155	PF00069	0.712
MOD_NEK2_1	254	259	PF00069	0.696
MOD_NEK2_1	290	295	PF00069	0.683
MOD_NEK2_1	364	369	PF00069	0.668
MOD_NEK2_1	499	504	PF00069	0.826
MOD_NEK2_1	93	98	PF00069	0.823
MOD_PIKK_1	212	218	PF00454	0.712
MOD_PIKK_1	290	296	PF00454	0.856
MOD_PIKK_1	353	359	PF00454	0.795
MOD_PIKK_1	462	468	PF00454	0.687
MOD_PK_1	190	196	PF00069	0.662
MOD_PKA_2	100	106	PF00069	0.660
MOD_PKA_2	146	152	PF00069	0.791
MOD_PKA_2	280	286	PF00069	0.685
MOD_PKA_2	345	351	PF00069	0.692
MOD_PKA_2	429	435	PF00069	0.686
MOD_PKA_2	481	487	PF00069	0.764
MOD_PKA_2	513	519	PF00069	0.669
MOD_Plk_1	540	546	PF00069	0.702
MOD_Plk_1	89	95	PF00069	0.813
MOD_Plk_2-3	219	225	PF00069	0.586
MOD_Plk_2-3	245	251	PF00069	0.673
MOD_Plk_4	16	22	PF00069	0.659
MOD_Plk_4	81	87	PF00069	0.823
MOD_Plk_4	89	95	PF00069	0.715
MOD_ProDKin_1	142	148	PF00069	0.778
MOD_ProDKin_1	29	35	PF00069	0.857
MOD_ProDKin_1	309	315	PF00069	0.834
MOD_ProDKin_1	318	324	PF00069	0.767
MOD_ProDKin_1	371	377	PF00069	0.807
MOD_ProDKin_1	439	445	PF00069	0.784
MOD_ProDKin_1	458	464	PF00069	0.686
MOD_ProDKin_1	466	472	PF00069	0.831
MOD_ProDKin_1	500	506	PF00069	0.809
MOD_ProDKin_1	516	522	PF00069	0.651
MOD_ProDKin_1	52	58	PF00069	0.687
MOD_ProDKin_1	545	551	PF00069	0.850
MOD_SUMO_for_1	182	185	PF00179	0.663
MOD_SUMO_rev_2	154	164	PF00179	0.662
MOD_SUMO_rev_2	215	223	PF00179	0.605
TRG_DiLeu_BaEn_1	43	48	PF01217	0.686
TRG_DiLeu_BaLyEn_6	9	14	PF01217	0.668
TRG_ENDOCYTIC_2	578	581	PF00928	0.798
TRG_ENDOCYTIC_2	94	97	PF00928	0.825
TRG_ER_diArg_1	343	346	PF00400	0.688
TRG_ER_diArg_1	511	514	PF00400	0.674
TRG_Pf-PMV_PEXEL_1	221	225	PF00026	0.470
TRG_Pf-PMV_PEXEL_1	536	541	PF00026	0.453

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4Q2	Leishmania donovani	56%	100%
A4I732	Leishmania infantum	56%	86%
E9B200	Leishmania mexicana (strain MHOM/GT/2001/U1103)	54%	100%
Q4Q661	Leishmania major	54%	98%