Publication identifier(s): 31356625
GPI-anchored cell surface protease. Broad-spectrum ectoenzyme involved in pathogenesis. Heavily expanded family in all parazitic species.. Localization: Cell surface (experimental)
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 2 |
| Forrest at al. (procyclic) | no | yes: 4 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 72 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 5 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 68, no: 18 |
| NetGPI | no | yes: 0, no: 86 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 87 |
| GO:0110165 | cellular anatomical entity | 1 | 87 |
| GO:0005737 | cytoplasm | 2 | 6 |
| GO:0018995 | host cellular component | 2 | 4 |
| GO:0033643 | host cell part | 3 | 4 |
| GO:0033646 | host intracellular part | 4 | 4 |
| GO:0033647 | host intracellular organelle | 5 | 4 |
| GO:0033648 | host intracellular membrane-bounded organelle | 6 | 4 |
| GO:0042025 | host cell nucleus | 7 | 4 |
Related structures:
AlphaFold database: A4HJI2
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006508 | proteolysis | 4 | 87 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 87 |
| GO:0007155 | cell adhesion | 2 | 87 |
| GO:0008152 | metabolic process | 1 | 87 |
| GO:0009987 | cellular process | 1 | 87 |
| GO:0019538 | protein metabolic process | 3 | 87 |
| GO:0043170 | macromolecule metabolic process | 3 | 87 |
| GO:0044238 | primary metabolic process | 2 | 87 |
| GO:0071704 | organic substance metabolic process | 2 | 87 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 87 |
| GO:0009966 | regulation of signal transduction | 4 | 4 |
| GO:0010646 | regulation of cell communication | 4 | 4 |
| GO:0010749 | regulation of nitric oxide mediated signal transduction | 6 | 4 |
| GO:0023051 | regulation of signaling | 3 | 4 |
| GO:0035821 | modulation of process of another organism | 2 | 4 |
| GO:0044003 | modulation by symbiont of host process | 3 | 4 |
| GO:0044068 | modulation by symbiont of host cellular process | 4 | 4 |
| GO:0044081 | modulation by symbiont of host nitric oxide-mediated signal transduction | 5 | 4 |
| GO:0044403 | biological process involved in symbiotic interaction | 2 | 4 |
| GO:0044419 | biological process involved in interspecies interaction between organisms | 1 | 4 |
| GO:0044501 | modulation of signal transduction in another organism | 3 | 4 |
| GO:0048583 | regulation of response to stimulus | 3 | 4 |
| GO:0050789 | regulation of biological process | 2 | 4 |
| GO:0050794 | regulation of cellular process | 3 | 4 |
| GO:0051701 | biological process involved in interaction with host | 3 | 4 |
| GO:0052027 | modulation by symbiont of host signal transduction pathway | 4 | 4 |
| GO:0065007 | biological regulation | 1 | 4 |
| GO:0075130 | modulation by symbiont of host protein kinase-mediated signal transduction | 5 | 4 |
| GO:1902531 | regulation of intracellular signal transduction | 5 | 4 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 87 |
| GO:0004175 | endopeptidase activity | 4 | 87 |
| GO:0004222 | metalloendopeptidase activity | 5 | 87 |
| GO:0005488 | binding | 1 | 87 |
| GO:0008233 | peptidase activity | 3 | 87 |
| GO:0008237 | metallopeptidase activity | 4 | 87 |
| GO:0016787 | hydrolase activity | 2 | 87 |
| GO:0043167 | ion binding | 2 | 87 |
| GO:0043169 | cation binding | 3 | 87 |
| GO:0046872 | metal ion binding | 4 | 87 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 87 |
| GO:0008047 | enzyme activator activity | 3 | 4 |
| GO:0008160 | protein tyrosine phosphatase activator activity | 6 | 4 |
| GO:0019208 | phosphatase regulator activity | 3 | 4 |
| GO:0019211 | phosphatase activator activity | 4 | 4 |
| GO:0019888 | protein phosphatase regulator activity | 4 | 4 |
| GO:0030234 | enzyme regulator activity | 2 | 4 |
| GO:0072542 | protein phosphatase activator activity | 5 | 4 |
| GO:0098772 | molecular function regulator activity | 1 | 4 |
| GO:0140677 | molecular function activator activity | 2 | 4 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 107 | 111 | PF00656 | 0.201 |
| CLV_NRD_NRD_1 | 293 | 295 | PF00675 | 0.549 |
| CLV_NRD_NRD_1 | 373 | 375 | PF00675 | 0.472 |
| CLV_NRD_NRD_1 | 68 | 70 | PF00675 | 0.661 |
| CLV_PCSK_KEX2_1 | 161 | 163 | PF00082 | 0.601 |
| CLV_PCSK_KEX2_1 | 293 | 295 | PF00082 | 0.546 |
| CLV_PCSK_KEX2_1 | 372 | 374 | PF00082 | 0.463 |
| CLV_PCSK_KEX2_1 | 589 | 591 | PF00082 | 0.448 |
| CLV_PCSK_KEX2_1 | 68 | 70 | PF00082 | 0.704 |
| CLV_PCSK_KEX2_1 | 83 | 85 | PF00082 | 0.639 |
| CLV_PCSK_PC1ET2_1 | 161 | 163 | PF00082 | 0.608 |
| CLV_PCSK_PC1ET2_1 | 372 | 374 | PF00082 | 0.491 |
| CLV_PCSK_PC1ET2_1 | 589 | 591 | PF00082 | 0.500 |
| CLV_PCSK_PC1ET2_1 | 83 | 85 | PF00082 | 0.588 |
| CLV_PCSK_SKI1_1 | 314 | 318 | PF00082 | 0.506 |
| CLV_PCSK_SKI1_1 | 374 | 378 | PF00082 | 0.519 |
| DEG_SCF_FBW7_2 | 120 | 126 | PF00400 | 0.283 |
| DOC_CDC14_PxL_1 | 317 | 325 | PF14671 | 0.332 |
| DOC_CKS1_1 | 120 | 125 | PF01111 | 0.283 |
| DOC_MAPK_gen_1 | 324 | 331 | PF00069 | 0.300 |
| DOC_MAPK_MEF2A_6 | 10 | 19 | PF00069 | 0.440 |
| DOC_MAPK_MEF2A_6 | 75 | 82 | PF00069 | 0.417 |
| DOC_MAPK_NFAT4_5 | 10 | 18 | PF00069 | 0.509 |
| DOC_PP1_RVXF_1 | 403 | 409 | PF00149 | 0.366 |
| DOC_PP2B_LxvP_1 | 380 | 383 | PF13499 | 0.404 |
| DOC_PP4_FxxP_1 | 204 | 207 | PF00568 | 0.324 |
| DOC_PP4_FxxP_1 | 425 | 428 | PF00568 | 0.215 |
| DOC_USP7_MATH_1 | 140 | 144 | PF00917 | 0.302 |
| DOC_USP7_MATH_1 | 28 | 32 | PF00917 | 0.536 |
| DOC_USP7_MATH_1 | 285 | 289 | PF00917 | 0.380 |
| DOC_USP7_MATH_1 | 364 | 368 | PF00917 | 0.320 |
| DOC_USP7_MATH_1 | 470 | 474 | PF00917 | 0.295 |
| DOC_USP7_MATH_1 | 5 | 9 | PF00917 | 0.681 |
| DOC_USP7_MATH_1 | 579 | 583 | PF00917 | 0.336 |
| DOC_USP7_MATH_1 | 618 | 622 | PF00917 | 0.460 |
| DOC_WW_Pin1_4 | 119 | 124 | PF00397 | 0.318 |
| DOC_WW_Pin1_4 | 228 | 233 | PF00397 | 0.311 |
| DOC_WW_Pin1_4 | 281 | 286 | PF00397 | 0.198 |
| DOC_WW_Pin1_4 | 43 | 48 | PF00397 | 0.375 |
| DOC_WW_Pin1_4 | 434 | 439 | PF00397 | 0.358 |
| DOC_WW_Pin1_4 | 531 | 536 | PF00397 | 0.409 |
| DOC_WW_Pin1_4 | 580 | 585 | PF00397 | 0.371 |
| LIG_14-3-3_CanoR_1 | 148 | 153 | PF00244 | 0.324 |
| LIG_14-3-3_CanoR_1 | 162 | 170 | PF00244 | 0.357 |
| LIG_14-3-3_CanoR_1 | 389 | 394 | PF00244 | 0.340 |
| LIG_14-3-3_CanoR_1 | 450 | 459 | PF00244 | 0.297 |
| LIG_14-3-3_CanoR_1 | 631 | 639 | PF00244 | 0.227 |
| LIG_14-3-3_CanoR_1 | 99 | 105 | PF00244 | 0.298 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.676 |
| LIG_BRCT_BRCA1_1 | 307 | 311 | PF00533 | 0.395 |
| LIG_FHA_1 | 120 | 126 | PF00498 | 0.367 |
| LIG_FHA_1 | 187 | 193 | PF00498 | 0.337 |
| LIG_FHA_1 | 210 | 216 | PF00498 | 0.298 |
| LIG_FHA_1 | 24 | 30 | PF00498 | 0.431 |
| LIG_FHA_1 | 246 | 252 | PF00498 | 0.406 |
| LIG_FHA_1 | 287 | 293 | PF00498 | 0.413 |
| LIG_FHA_1 | 305 | 311 | PF00498 | 0.357 |
| LIG_FHA_1 | 348 | 354 | PF00498 | 0.352 |
| LIG_FHA_1 | 435 | 441 | PF00498 | 0.335 |
| LIG_FHA_1 | 552 | 558 | PF00498 | 0.404 |
| LIG_FHA_1 | 631 | 637 | PF00498 | 0.341 |
| LIG_FHA_2 | 272 | 278 | PF00498 | 0.216 |
| LIG_LIR_Apic_2 | 203 | 207 | PF02991 | 0.335 |
| LIG_LIR_Apic_2 | 600 | 606 | PF02991 | 0.281 |
| LIG_LIR_Gen_1 | 552 | 562 | PF02991 | 0.343 |
| LIG_LIR_LC3C_4 | 529 | 532 | PF02991 | 0.194 |
| LIG_LIR_Nem_3 | 110 | 116 | PF02991 | 0.289 |
| LIG_LIR_Nem_3 | 217 | 223 | PF02991 | 0.390 |
| LIG_LIR_Nem_3 | 400 | 406 | PF02991 | 0.358 |
| LIG_LIR_Nem_3 | 473 | 477 | PF02991 | 0.372 |
| LIG_LIR_Nem_3 | 491 | 496 | PF02991 | 0.284 |
| LIG_LIR_Nem_3 | 552 | 558 | PF02991 | 0.370 |
| LIG_LIR_Nem_3 | 63 | 67 | PF02991 | 0.552 |
| LIG_PTB_Apo_2 | 260 | 267 | PF02174 | 0.268 |
| LIG_PTB_Phospho_1 | 260 | 266 | PF10480 | 0.276 |
| LIG_RPA_C_Fungi | 384 | 396 | PF08784 | 0.224 |
| LIG_SH2_CRK | 390 | 394 | PF00017 | 0.415 |
| LIG_SH2_CRK | 493 | 497 | PF00017 | 0.466 |
| LIG_SH2_CRK | 555 | 559 | PF00017 | 0.536 |
| LIG_SH2_CRK | 603 | 607 | PF00017 | 0.233 |
| LIG_SH2_CRK | 64 | 68 | PF00017 | 0.503 |
| LIG_SH2_GRB2like | 261 | 264 | PF00017 | 0.456 |
| LIG_SH2_GRB2like | 603 | 606 | PF00017 | 0.456 |
| LIG_SH2_SRC | 598 | 601 | PF00017 | 0.389 |
| LIG_SH2_SRC | 603 | 606 | PF00017 | 0.389 |
| LIG_SH2_STAP1 | 467 | 471 | PF00017 | 0.229 |
| LIG_SH2_STAP1 | 474 | 478 | PF00017 | 0.218 |
| LIG_SH2_STAP1 | 555 | 559 | PF00017 | 0.526 |
| LIG_SH2_STAT5 | 131 | 134 | PF00017 | 0.311 |
| LIG_SH2_STAT5 | 21 | 24 | PF00017 | 0.302 |
| LIG_SH2_STAT5 | 223 | 226 | PF00017 | 0.370 |
| LIG_SH2_STAT5 | 261 | 264 | PF00017 | 0.348 |
| LIG_SH2_STAT5 | 266 | 269 | PF00017 | 0.341 |
| LIG_SH2_STAT5 | 477 | 480 | PF00017 | 0.377 |
| LIG_SH2_STAT5 | 493 | 496 | PF00017 | 0.320 |
| LIG_SH3_3 | 117 | 123 | PF00018 | 0.452 |
| LIG_SH3_3 | 179 | 185 | PF00018 | 0.259 |
| LIG_SH3_3 | 210 | 216 | PF00018 | 0.508 |
| LIG_SH3_3 | 476 | 482 | PF00018 | 0.355 |
| LIG_SH3_3 | 493 | 499 | PF00018 | 0.457 |
| LIG_SH3_3 | 529 | 535 | PF00018 | 0.275 |
| LIG_SH3_3 | 578 | 584 | PF00018 | 0.316 |
| LIG_SUMO_SIM_anti_2 | 611 | 617 | PF11976 | 0.371 |
| LIG_SUMO_SIM_par_1 | 188 | 195 | PF11976 | 0.196 |
| LIG_TRAF2_1 | 274 | 277 | PF00917 | 0.320 |
| LIG_TYR_ITIM | 62 | 67 | PF00017 | 0.508 |
| MOD_CDK_SPK_2 | 228 | 233 | PF00069 | 0.456 |
| MOD_CK1_1 | 105 | 111 | PF00069 | 0.492 |
| MOD_CK1_1 | 142 | 148 | PF00069 | 0.487 |
| MOD_CK1_1 | 391 | 397 | PF00069 | 0.355 |
| MOD_CK1_1 | 444 | 450 | PF00069 | 0.416 |
| MOD_CK1_1 | 534 | 540 | PF00069 | 0.386 |
| MOD_CK1_1 | 55 | 61 | PF00069 | 0.469 |
| MOD_CK1_1 | 560 | 566 | PF00069 | 0.345 |
| MOD_CK1_1 | 88 | 94 | PF00069 | 0.809 |
| MOD_CK2_1 | 267 | 273 | PF00069 | 0.295 |
| MOD_CK2_1 | 406 | 412 | PF00069 | 0.447 |
| MOD_Cter_Amidation | 324 | 327 | PF01082 | 0.266 |
| MOD_GlcNHglycan | 110 | 113 | PF01048 | 0.381 |
| MOD_GlcNHglycan | 141 | 145 | PF01048 | 0.412 |
| MOD_GlcNHglycan | 307 | 310 | PF01048 | 0.447 |
| MOD_GlcNHglycan | 31 | 34 | PF01048 | 0.486 |
| MOD_GlcNHglycan | 334 | 337 | PF01048 | 0.411 |
| MOD_GlcNHglycan | 447 | 450 | PF01048 | 0.476 |
| MOD_GlcNHglycan | 468 | 471 | PF01048 | 0.522 |
| MOD_GlcNHglycan | 559 | 562 | PF01048 | 0.426 |
| MOD_GlcNHglycan | 633 | 636 | PF01048 | 0.456 |
| MOD_GlcNHglycan | 87 | 90 | PF01048 | 0.799 |
| MOD_GSK3_1 | 126 | 133 | PF00069 | 0.357 |
| MOD_GSK3_1 | 160 | 167 | PF00069 | 0.323 |
| MOD_GSK3_1 | 192 | 199 | PF00069 | 0.398 |
| MOD_GSK3_1 | 227 | 234 | PF00069 | 0.347 |
| MOD_GSK3_1 | 245 | 252 | PF00069 | 0.294 |
| MOD_GSK3_1 | 267 | 274 | PF00069 | 0.293 |
| MOD_GSK3_1 | 281 | 288 | PF00069 | 0.498 |
| MOD_GSK3_1 | 428 | 435 | PF00069 | 0.260 |
| MOD_GSK3_1 | 441 | 448 | PF00069 | 0.325 |
| MOD_GSK3_1 | 462 | 469 | PF00069 | 0.411 |
| MOD_GSK3_1 | 480 | 487 | PF00069 | 0.344 |
| MOD_GSK3_1 | 560 | 567 | PF00069 | 0.371 |
| MOD_GSK3_1 | 614 | 621 | PF00069 | 0.571 |
| MOD_LATS_1 | 629 | 635 | PF00433 | 0.196 |
| MOD_N-GLC_1 | 332 | 337 | PF02516 | 0.438 |
| MOD_N-GLC_1 | 406 | 411 | PF02516 | 0.237 |
| MOD_N-GLC_1 | 549 | 554 | PF02516 | 0.318 |
| MOD_N-GLC_1 | 85 | 90 | PF02516 | 0.816 |
| MOD_NEK2_1 | 164 | 169 | PF00069 | 0.502 |
| MOD_NEK2_1 | 286 | 291 | PF00069 | 0.460 |
| MOD_NEK2_1 | 304 | 309 | PF00069 | 0.445 |
| MOD_NEK2_1 | 316 | 321 | PF00069 | 0.393 |
| MOD_NEK2_1 | 332 | 337 | PF00069 | 0.304 |
| MOD_NEK2_1 | 441 | 446 | PF00069 | 0.273 |
| MOD_NEK2_1 | 484 | 489 | PF00069 | 0.431 |
| MOD_NEK2_1 | 500 | 505 | PF00069 | 0.276 |
| MOD_NEK2_1 | 85 | 90 | PF00069 | 0.719 |
| MOD_PIKK_1 | 271 | 277 | PF00454 | 0.397 |
| MOD_PIKK_1 | 406 | 412 | PF00454 | 0.196 |
| MOD_PK_1 | 148 | 154 | PF00069 | 0.389 |
| MOD_PKA_1 | 160 | 166 | PF00069 | 0.490 |
| MOD_PKA_1 | 589 | 595 | PF00069 | 0.196 |
| MOD_PKA_1 | 68 | 74 | PF00069 | 0.461 |
| MOD_PKA_2 | 147 | 153 | PF00069 | 0.516 |
| MOD_PKA_2 | 388 | 394 | PF00069 | 0.407 |
| MOD_PKA_2 | 444 | 450 | PF00069 | 0.331 |
| MOD_PKA_2 | 455 | 461 | PF00069 | 0.341 |
| MOD_PKA_2 | 589 | 595 | PF00069 | 0.226 |
| MOD_PKA_2 | 630 | 636 | PF00069 | 0.344 |
| MOD_PKA_2 | 68 | 74 | PF00069 | 0.650 |
| MOD_Plk_1 | 187 | 193 | PF00069 | 0.264 |
| MOD_Plk_1 | 332 | 338 | PF00069 | 0.382 |
| MOD_Plk_4 | 142 | 148 | PF00069 | 0.402 |
| MOD_Plk_4 | 164 | 170 | PF00069 | 0.420 |
| MOD_Plk_4 | 187 | 193 | PF00069 | 0.467 |
| MOD_Plk_4 | 436 | 442 | PF00069 | 0.335 |
| MOD_Plk_4 | 560 | 566 | PF00069 | 0.327 |
| MOD_Plk_4 | 60 | 66 | PF00069 | 0.633 |
| MOD_ProDKin_1 | 119 | 125 | PF00069 | 0.370 |
| MOD_ProDKin_1 | 228 | 234 | PF00069 | 0.360 |
| MOD_ProDKin_1 | 281 | 287 | PF00069 | 0.202 |
| MOD_ProDKin_1 | 43 | 49 | PF00069 | 0.448 |
| MOD_ProDKin_1 | 434 | 440 | PF00069 | 0.425 |
| MOD_ProDKin_1 | 531 | 537 | PF00069 | 0.496 |
| MOD_ProDKin_1 | 580 | 586 | PF00069 | 0.444 |
| MOD_SUMO_for_1 | 376 | 379 | PF00179 | 0.382 |
| TRG_ENDOCYTIC_2 | 21 | 24 | PF00928 | 0.462 |
| TRG_ENDOCYTIC_2 | 390 | 393 | PF00928 | 0.356 |
| TRG_ENDOCYTIC_2 | 493 | 496 | PF00928 | 0.416 |
| TRG_ENDOCYTIC_2 | 555 | 558 | PF00928 | 0.514 |
| TRG_ENDOCYTIC_2 | 598 | 601 | PF00928 | 0.372 |
| TRG_ENDOCYTIC_2 | 64 | 67 | PF00928 | 0.735 |
| TRG_ER_diArg_1 | 292 | 294 | PF00400 | 0.457 |
| TRG_ER_diArg_1 | 67 | 69 | PF00400 | 0.616 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1IL11 | Leptomonas seymouri | 56% | 99% |
| A0A0S4IN60 | Bodo saltans | 32% | 72% |
| A0A0S4IUT6 | Bodo saltans | 32% | 79% |
| A0A0S4IUU1 | Bodo saltans | 30% | 98% |
| A0A1D5NSK0 | Danio rerio | 24% | 100% |
| A0A1X0NDG7 | Trypanosomatidae | 31% | 99% |
| A0A1X0NDJ3 | Trypanosomatidae | 27% | 90% |
| A0A1X0NDK2 | Trypanosomatidae | 29% | 100% |
| A0A1X0NDK7 | Trypanosomatidae | 29% | 91% |
| A0A1X0NDK9 | Trypanosomatidae | 29% | 100% |
| A0A1X0NDM7 | Trypanosomatidae | 28% | 100% |
| A0A1X0NDU8 | Trypanosomatidae | 28% | 97% |
| A0A1X0NE71 | Trypanosomatidae | 29% | 100% |
| A0A1X0NEE9 | Trypanosomatidae | 27% | 70% |
| A0A1X0NER9 | Trypanosomatidae | 29% | 100% |
| A0A1X0NET7 | Trypanosomatidae | 29% | 100% |
| A0A1X0NEX7 | Trypanosomatidae | 28% | 99% |
| A0A1X0NEZ6 | Trypanosomatidae | 29% | 99% |
| A0A1X0NF32 | Trypanosomatidae | 28% | 100% |
| A0A1X0NF41 | Trypanosomatidae | 30% | 100% |
| A0A1X0NFJ0 | Trypanosomatidae | 29% | 100% |
| A0A1X0NFK3 | Trypanosomatidae | 29% | 97% |
| A0A1X0NFL1 | Trypanosomatidae | 28% | 69% |
| A0A1X0NFS0 | Trypanosomatidae | 30% | 75% |
| A0A1X0NFT1 | Trypanosomatidae | 28% | 71% |
| A0A1X0NFU4 | Trypanosomatidae | 28% | 79% |
| A0A1X0NFZ9 | Trypanosomatidae | 30% | 100% |
| A0A1X0NG20 | Trypanosomatidae | 30% | 100% |
| A0A1X0NGP3 | Trypanosomatidae | 27% | 76% |
| A0A1X0NGY3 | Trypanosomatidae | 28% | 84% |
| A0A1X0NGZ3 | Trypanosomatidae | 30% | 100% |
| A0A1X0NH86 | Trypanosomatidae | 30% | 73% |
| A0A1X0NHP6 | Trypanosomatidae | 28% | 100% |
| A0A1X0NHQ6 | Trypanosomatidae | 28% | 100% |
| A0A1X0NI38 | Trypanosomatidae | 28% | 74% |
| A0A1X0NI74 | Trypanosomatidae | 29% | 87% |
| A0A1X0NII4 | Trypanosomatidae | 28% | 77% |
| A0A1X0NIZ3 | Trypanosomatidae | 31% | 100% |
| A0A1X0NJS3 | Trypanosomatidae | 30% | 99% |
| A0A1X0NJU4 | Trypanosomatidae | 28% | 75% |
| A0A1X0NK29 | Trypanosomatidae | 29% | 70% |
| A0A1X0NK66 | Trypanosomatidae | 30% | 98% |
| A0A1X0NKJ8 | Trypanosomatidae | 28% | 87% |
| A0A1X0NKW9 | Trypanosomatidae | 33% | 100% |
| A0A1X0NME2 | Trypanosomatidae | 28% | 100% |
| A0A1X0NMK3 | Trypanosomatidae | 27% | 100% |
| A0A1X0NMK7 | Trypanosomatidae | 34% | 100% |
| A0A1X0NMV0 | Trypanosomatidae | 29% | 88% |
| A0A1X0NN43 | Trypanosomatidae | 28% | 90% |
| A0A1X0NNK8 | Trypanosomatidae | 28% | 98% |
| A0A1X0NP64 | Trypanosomatidae | 29% | 73% |
| A0A1X0NPW0 | Trypanosomatidae | 28% | 100% |
| A0A1X0NQM4 | Trypanosomatidae | 33% | 100% |
| A0A1X0NQN3 | Trypanosomatidae | 34% | 100% |
| A0A1X0NQU4 | Trypanosomatidae | 34% | 100% |
| A0A1X0NQW6 | Trypanosomatidae | 32% | 100% |
| A0A1X0NRF3 | Trypanosomatidae | 29% | 96% |
| A0A1X0NRY8 | Trypanosomatidae | 34% | 100% |
| A0A1X0NU16 | Trypanosomatidae | 36% | 100% |
| A0A1X0NUR2 | Trypanosomatidae | 32% | 88% |
| A0A1X0NV28 | Trypanosomatidae | 37% | 100% |
| A0A1X0NVC3 | Trypanosomatidae | 31% | 95% |
| A0A1X0NVE0 | Trypanosomatidae | 31% | 83% |
| A0A1X0NW07 | Trypanosomatidae | 26% | 100% |
| A0A1X0NX94 | Trypanosomatidae | 30% | 100% |
| A0A1X0NX98 | Trypanosomatidae | 28% | 81% |
| A0A1X0NXB6 | Trypanosomatidae | 27% | 92% |
| A0A1X0NXH6 | Trypanosomatidae | 34% | 89% |
| A0A1X0NXQ4 | Trypanosomatidae | 30% | 96% |
| A0A1X0NXR7 | Trypanosomatidae | 34% | 86% |
| A0A1X0NYE3 | Trypanosomatidae | 31% | 100% |
| A0A1X0NYE7 | Trypanosomatidae | 30% | 100% |
| A0A1X0NYN2 | Trypanosomatidae | 33% | 100% |
| A0A1X0NYN4 | Trypanosomatidae | 27% | 91% |
| A0A1X0NYS5 | Trypanosomatidae | 33% | 100% |
| A0A1X0NYZ2 | Trypanosomatidae | 37% | 100% |
| A0A1X0NZ46 | Trypanosomatidae | 28% | 100% |
| A0A1X0NZ63 | Trypanosomatidae | 29% | 100% |
| A0A1X0NZN6 | Trypanosomatidae | 29% | 100% |
| A0A1X0P055 | Trypanosomatidae | 34% | 100% |
| A0A1X0P154 | Trypanosomatidae | 30% | 100% |
| A0A1X0P331 | Trypanosomatidae | 35% | 100% |
| A0A1X0P3K0 | Trypanosomatidae | 28% | 89% |
| A0A1X0P3S2 | Trypanosomatidae | 27% | 100% |
| A0A1X0P4L8 | Trypanosomatidae | 28% | 100% |
| A0A1X0P4Y5 | Trypanosomatidae | 27% | 100% |
| A0A1X0P544 | Trypanosomatidae | 30% | 100% |
| A0A1X0P5J0 | Trypanosomatidae | 33% | 94% |
| A0A1X0P6H3 | Trypanosomatidae | 32% | 67% |
| A0A1X0P7K5 | Trypanosomatidae | 28% | 73% |
| A0A1X0P7R3 | Trypanosomatidae | 36% | 100% |
| A0A1X0P8B4 | Trypanosomatidae | 29% | 100% |
| A0A1X0P9Z4 | Trypanosomatidae | 28% | 100% |
| A0A1X0PB04 | Trypanosomatidae | 31% | 100% |
| A0A3Q8I8N3 | Leishmania donovani | 36% | 100% |
| A0A3Q8I8P8 | Leishmania donovani | 36% | 100% |
| A0A3Q8I8S6 | Leishmania donovani | 36% | 100% |
| A0A3Q8I8S9 | Leishmania donovani | 36% | 100% |
| A0A3Q8IAZ8 | Leishmania donovani | 36% | 100% |
| A0A3Q8IC35 | Leishmania donovani | 36% | 100% |
| A0A3Q8IC44 | Leishmania donovani | 36% | 100% |
| A0A3Q8IH61 | Leishmania donovani | 36% | 100% |
| A0A3Q8IIN4 | Leishmania donovani | 78% | 100% |
| A0A3R7JT49 | Trypanosoma rangeli | 35% | 77% |
| A0A3R7JTB6 | Trypanosoma rangeli | 32% | 92% |
| A0A3R7JV87 | Trypanosoma rangeli | 36% | 100% |
| A0A3R7K7T9 | Trypanosoma rangeli | 32% | 100% |
| A0A3R7K9S1 | Trypanosoma rangeli | 37% | 100% |
| A0A3R7KB14 | Trypanosoma rangeli | 33% | 74% |
| A0A3R7KLR6 | Trypanosoma rangeli | 31% | 100% |
| A0A3R7KMY2 | Trypanosoma rangeli | 37% | 97% |
| A0A3R7LFC4 | Trypanosoma rangeli | 37% | 96% |
| A0A3R7LFZ4 | Trypanosoma rangeli | 39% | 100% |
| A0A3R7LWG1 | Trypanosoma rangeli | 31% | 100% |
| A0A3R7LX11 | Trypanosoma rangeli | 37% | 100% |
| A0A3R7M1R8 | Trypanosoma rangeli | 36% | 100% |
| A0A3R7M574 | Trypanosoma rangeli | 36% | 100% |
| A0A3R7M7N6 | Trypanosoma rangeli | 36% | 94% |
| A0A3R7MTS2 | Trypanosoma rangeli | 37% | 100% |
| A0A3R7MW36 | Trypanosoma rangeli | 34% | 100% |
| A0A3R7MXF4 | Trypanosoma rangeli | 36% | 100% |
| A0A3R7N1W7 | Trypanosoma rangeli | 31% | 100% |
| A0A3R7N289 | Trypanosoma rangeli | 35% | 89% |
| A0A3R7NTI8 | Trypanosoma rangeli | 35% | 100% |
| A0A3R7R2J4 | Trypanosoma rangeli | 36% | 100% |
| A0A3R7R5R1 | Trypanosoma rangeli | 31% | 100% |
| A0A3R7R818 | Trypanosoma rangeli | 32% | 100% |
| A0A3S5H6G0 | Leishmania donovani | 36% | 100% |
| A0A3S5IQY2 | Trypanosoma rangeli | 36% | 100% |
| A0A3S7WR43 | Leishmania donovani | 36% | 100% |
| A0A3S7WR46 | Leishmania donovani | 36% | 100% |
| A0A3S7WR60 | Leishmania donovani | 36% | 100% |
| A0A3S7X192 | Leishmania donovani | 40% | 100% |
| A0A422MP17 | Trypanosoma rangeli | 32% | 100% |
| A0A422MRQ6 | Trypanosoma rangeli | 36% | 87% |
| A0A422MU95 | Trypanosoma rangeli | 35% | 100% |
| A0A422MVF5 | Trypanosoma rangeli | 32% | 100% |
| A0A422MVS3 | Trypanosoma rangeli | 31% | 100% |
| A0A422MW99 | Trypanosoma rangeli | 29% | 87% |
| A0A422MZ47 | Trypanosoma rangeli | 38% | 100% |
| A0A422MZG4 | Trypanosoma rangeli | 35% | 100% |
| A0A422N361 | Trypanosoma rangeli | 35% | 100% |
| A0A422N7Q6 | Trypanosoma rangeli | 36% | 100% |
| A0A422NDS2 | Trypanosoma rangeli | 34% | 100% |
| A0A422NDT3 | Trypanosoma rangeli | 32% | 100% |
| A0A422NP82 | Trypanosoma rangeli | 39% | 100% |
| A4H626 | Leishmania braziliensis | 36% | 100% |
| A4H627 | Leishmania braziliensis | 33% | 100% |
| A4H630 | Leishmania braziliensis | 37% | 100% |
| A4H631 | Leishmania braziliensis | 38% | 100% |
| A4H632 | Leishmania braziliensis | 36% | 100% |
| A4H633 | Leishmania braziliensis | 39% | 100% |
| A4H634 | Leishmania braziliensis | 38% | 100% |
| A4H635 | Leishmania braziliensis | 38% | 100% |
| A4H636 | Leishmania braziliensis | 33% | 94% |
| A4H637 | Leishmania braziliensis | 38% | 100% |
| A4H638 | Leishmania braziliensis | 36% | 100% |
| A4H639 | Leishmania braziliensis | 37% | 100% |
| A4H640 | Leishmania braziliensis | 38% | 100% |
| A4H6D3 | Leishmania braziliensis | 35% | 100% |
| A4H6D5 | Leishmania braziliensis | 36% | 100% |
| A4H6D7 | Leishmania braziliensis | 33% | 100% |
| A4H6D8 | Leishmania braziliensis | 36% | 100% |
| A4H6D9 | Leishmania braziliensis | 36% | 100% |
| A4H6E0 | Leishmania braziliensis | 36% | 100% |
| A4H6E1 | Leishmania braziliensis | 35% | 100% |
| A4H6E2 | Leishmania braziliensis | 35% | 100% |
| A4H6E3 | Leishmania braziliensis | 37% | 100% |
| A4H6E5 | Leishmania braziliensis | 38% | 100% |
| A4HUF6 | Leishmania infantum | 37% | 100% |
| A4HUF8 | Leishmania infantum | 36% | 100% |
| A4HUF9 | Leishmania infantum | 36% | 100% |
| A4HUG0 | Leishmania infantum | 35% | 85% |
| A4I6X5 | Leishmania infantum | 78% | 100% |
| C9ZUT5 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 36% | 100% |
| D0A1R8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 31% | 100% |
| D0A7S8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 27% | 96% |
| D0A855 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 32% | 100% |
| E9AHH5 | Leishmania infantum | 40% | 100% |
| E9AN53 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 37% | 99% |
| E9AN54 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 37% | 100% |
| E9AN55 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 37% | 100% |
| E9AN56 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 37% | 100% |
| E9AN57 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 38% | 100% |
| E9AZL8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 41% | 100% |
| E9B1Z9 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 75% | 100% |
| O62446 | Caenorhabditis elegans | 25% | 98% |
| P08148 | Leishmania major | 38% | 100% |
| P15706 | Leishmania chagasi | 36% | 100% |
| P23223 | Leishmania donovani | 36% | 100% |
| P43150 | Leishmania mexicana | 37% | 100% |
| Q00689 | Leishmania guyanensis | 38% | 100% |
| Q06031 | Crithidia fasciculata | 35% | 99% |
| Q27673 | Leishmania amazonensis | 36% | 100% |
| Q29AK2 | Drosophila pseudoobscura pseudoobscura | 24% | 95% |
| Q4Q662 | Leishmania major | 79% | 100% |
| Q4Q8L3 | Leishmania major | 39% | 100% |
| Q4QHG9 | Leishmania major | 36% | 100% |
| Q4QHH0 | Leishmania major | 35% | 100% |
| Q4QHH1 | Leishmania major | 36% | 100% |
| Q4QHH2 | Leishmania major | 37% | 100% |
| Q61YG1 | Caenorhabditis briggsae | 25% | 98% |
| Q6LA77 | Leishmania infantum | 36% | 100% |
| Q8BMN4 | Mus musculus | 25% | 95% |
| Q8MNZ1 | Leishmania tropica | 36% | 99% |
| Q9VH19 | Drosophila melanogaster | 24% | 95% |
| V5A359 | Trypanosoma cruzi | 38% | 100% |
| V5A488 | Trypanosoma cruzi | 31% | 80% |
| V5AII7 | Trypanosoma cruzi | 38% | 100% |
| V5APQ4 | Trypanosoma cruzi | 32% | 82% |
| V5AX72 | Trypanosoma cruzi | 33% | 88% |
| V5B5M0 | Trypanosoma cruzi | 33% | 88% |
| V5B9W5 | Trypanosoma cruzi | 29% | 96% |
| V5BAN1 | Trypanosoma cruzi | 32% | 82% |
| V5BLT3 | Trypanosoma cruzi | 32% | 100% |
| V5CI97 | Trypanosoma cruzi | 29% | 100% |
| V5D358 | Trypanosoma cruzi | 33% | 76% |