Putative transcription like protein nupm1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription like protein nupm1, putative

Species:

Leishmania braziliensis

UniProt:

A4HJH6_LEIBR

TriTrypDb:

LbrM.31.2170 , LBRM2903_310031800

Length:

459

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A4HJH6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJH6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	138	142	PF00656	0.671
CLV_C14_Caspase3-7	41	45	PF00656	0.660
CLV_NRD_NRD_1	103	105	PF00675	0.460
CLV_NRD_NRD_1	110	112	PF00675	0.457
CLV_NRD_NRD_1	192	194	PF00675	0.556
CLV_NRD_NRD_1	232	234	PF00675	0.484
CLV_NRD_NRD_1	282	284	PF00675	0.542
CLV_NRD_NRD_1	299	301	PF00675	0.492
CLV_NRD_NRD_1	402	404	PF00675	0.570
CLV_PCSK_FUR_1	100	104	PF00082	0.372
CLV_PCSK_FUR_1	229	233	PF00082	0.490
CLV_PCSK_KEX2_1	102	104	PF00082	0.462
CLV_PCSK_KEX2_1	110	112	PF00082	0.453
CLV_PCSK_KEX2_1	192	194	PF00082	0.556
CLV_PCSK_KEX2_1	231	233	PF00082	0.491
CLV_PCSK_KEX2_1	281	283	PF00082	0.544
CLV_PCSK_KEX2_1	298	300	PF00082	0.493
CLV_PCSK_KEX2_1	402	404	PF00082	0.576
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.462
CLV_PCSK_PC7_1	227	233	PF00082	0.473
CLV_PCSK_SKI1_1	285	289	PF00082	0.523
CLV_Separin_Metazoa	91	95	PF03568	0.665
DEG_Kelch_Keap1_1	61	66	PF01344	0.832
DEG_Nend_UBRbox_2	1	3	PF02207	0.373
DEG_SCF_FBW7_2	84	91	PF00400	0.646
DOC_PP4_FxxP_1	421	424	PF00568	0.740
DOC_USP7_MATH_1	140	144	PF00917	0.830
DOC_USP7_MATH_1	287	291	PF00917	0.845
DOC_USP7_MATH_1	353	357	PF00917	0.836
DOC_USP7_MATH_1	372	376	PF00917	0.638
DOC_USP7_MATH_1	78	82	PF00917	0.719
DOC_USP7_UBL2_3	405	409	PF12436	0.759
DOC_WW_Pin1_4	172	177	PF00397	0.652
DOC_WW_Pin1_4	254	259	PF00397	0.683
DOC_WW_Pin1_4	358	363	PF00397	0.699
DOC_WW_Pin1_4	374	379	PF00397	0.735
DOC_WW_Pin1_4	84	89	PF00397	0.651
LIG_14-3-3_CanoR_1	148	152	PF00244	0.763
LIG_14-3-3_CanoR_1	159	165	PF00244	0.774
LIG_14-3-3_CanoR_1	299	305	PF00244	0.784
LIG_14-3-3_CanoR_1	403	409	PF00244	0.742
LIG_BIR_III_4	352	356	PF00653	0.676
LIG_BRCT_BRCA1_1	28	32	PF00533	0.438
LIG_BRCT_BRCA1_1	417	421	PF00533	0.744
LIG_BRCT_BRCA1_1	7	11	PF00533	0.290
LIG_FHA_1	54	60	PF00498	0.678
LIG_FHA_2	131	137	PF00498	0.692
LIG_FHA_2	273	279	PF00498	0.719
LIG_LIR_Apic_2	170	174	PF02991	0.804
LIG_LIR_Apic_2	418	424	PF02991	0.733
LIG_LIR_Gen_1	6	17	PF02991	0.260
LIG_LIR_Nem_3	321	326	PF02991	0.825
LIG_LIR_Nem_3	360	366	PF02991	0.668
LIG_LIR_Nem_3	407	411	PF02991	0.688
LIG_LIR_Nem_3	6	12	PF02991	0.260
LIG_LIR_Nem_3	71	77	PF02991	0.783
LIG_LYPXL_yS_3	323	326	PF13949	0.823
LIG_MLH1_MIPbox_1	417	421	PF16413	0.744
LIG_MYND_1	84	88	PF01753	0.689
LIG_PCNA_yPIPBox_3	409	421	PF02747	0.738
LIG_REV1ctd_RIR_1	418	423	PF16727	0.664
LIG_SH2_GRB2like	388	391	PF00017	0.696
LIG_SH2_STAT5	171	174	PF00017	0.741
LIG_SH3_3	25	31	PF00018	0.290
LIG_SH3_3	306	312	PF00018	0.701
LIG_SH3_3	359	365	PF00018	0.667
LIG_TRAF2_1	106	109	PF00917	0.660
LIG_TRAF2_1	88	91	PF00917	0.681
LIG_WW_3	82	86	PF00397	0.631
MOD_CDK_SPxxK_3	254	261	PF00069	0.607
MOD_CK1_1	143	149	PF00069	0.712
MOD_CK1_1	194	200	PF00069	0.740
MOD_CK1_1	203	209	PF00069	0.734
MOD_CK1_1	212	218	PF00069	0.731
MOD_CK1_1	254	260	PF00069	0.702
MOD_CK1_1	264	270	PF00069	0.731
MOD_CK1_1	303	309	PF00069	0.734
MOD_CK2_1	130	136	PF00069	0.811
MOD_CK2_1	272	278	PF00069	0.619
MOD_CK2_1	60	66	PF00069	0.814
MOD_CK2_1	67	73	PF00069	0.678
MOD_Cter_Amidation	279	282	PF01082	0.637
MOD_GlcNHglycan	13	16	PF01048	0.439
MOD_GlcNHglycan	152	155	PF01048	0.654
MOD_GlcNHglycan	197	200	PF01048	0.762
MOD_GlcNHglycan	263	266	PF01048	0.781
MOD_GlcNHglycan	306	309	PF01048	0.713
MOD_GlcNHglycan	394	398	PF01048	0.655
MOD_GlcNHglycan	417	420	PF01048	0.625
MOD_GSK3_1	1	8	PF00069	0.467
MOD_GSK3_1	140	147	PF00069	0.661
MOD_GSK3_1	150	157	PF00069	0.642
MOD_GSK3_1	191	198	PF00069	0.665
MOD_GSK3_1	250	257	PF00069	0.675
MOD_GSK3_1	259	266	PF00069	0.726
MOD_GSK3_1	26	33	PF00069	0.438
MOD_GSK3_1	299	306	PF00069	0.741
MOD_GSK3_1	315	322	PF00069	0.722
MOD_GSK3_1	343	350	PF00069	0.722
MOD_GSK3_1	353	360	PF00069	0.664
MOD_GSK3_1	366	373	PF00069	0.566
MOD_GSK3_1	374	381	PF00069	0.801
MOD_GSK3_1	389	396	PF00069	0.667
MOD_LATS_1	297	303	PF00433	0.614
MOD_N-GLC_1	389	394	PF02516	0.686
MOD_NEK2_1	1	6	PF00069	0.549
MOD_NEK2_1	11	16	PF00069	0.414
MOD_NEK2_1	26	31	PF00069	0.515
MOD_NEK2_1	263	268	PF00069	0.755
MOD_NEK2_1	366	371	PF00069	0.633
MOD_NEK2_1	59	64	PF00069	0.815
MOD_PIKK_1	209	215	PF00454	0.717
MOD_PIKK_1	264	270	PF00454	0.834
MOD_PK_1	300	306	PF00069	0.746
MOD_PKA_1	192	198	PF00069	0.704
MOD_PKA_1	281	287	PF00069	0.688
MOD_PKA_1	298	304	PF00069	0.618
MOD_PKA_2	147	153	PF00069	0.713
MOD_PKA_2	167	173	PF00069	0.509
MOD_PKA_2	191	197	PF00069	0.784
MOD_PKA_2	200	206	PF00069	0.682
MOD_PKA_2	209	215	PF00069	0.539
MOD_PKA_2	281	287	PF00069	0.688
MOD_PKA_2	298	304	PF00069	0.648
MOD_PKA_2	422	428	PF00069	0.585
MOD_PKB_1	291	299	PF00069	0.717
MOD_Plk_1	1	7	PF00069	0.419
MOD_Plk_2-3	132	138	PF00069	0.581
MOD_Plk_2-3	347	353	PF00069	0.616
MOD_Plk_4	13	19	PF00069	0.316
MOD_Plk_4	167	173	PF00069	0.743
MOD_Plk_4	5	11	PF00069	0.485
MOD_ProDKin_1	172	178	PF00069	0.562
MOD_ProDKin_1	254	260	PF00069	0.603
MOD_ProDKin_1	358	364	PF00069	0.625
MOD_ProDKin_1	374	380	PF00069	0.677
MOD_ProDKin_1	84	90	PF00069	0.554
TRG_ENDOCYTIC_2	323	326	PF00928	0.695
TRG_ER_diArg_1	222	225	PF00400	0.628
TRG_ER_diArg_1	227	230	PF00400	0.614
TRG_ER_diArg_1	231	233	PF00400	0.613
TRG_ER_diArg_1	281	283	PF00400	0.771
TRG_ER_diArg_1	291	294	PF00400	0.646
TRG_ER_diArg_1	298	300	PF00400	0.647
TRG_ER_diArg_1	401	403	PF00400	0.722
TRG_NLS_MonoCore_2	101	106	PF00514	0.535
TRG_NLS_MonoExtC_3	103	109	PF00514	0.447
TRG_NLS_MonoExtN_4	100	106	PF00514	0.567

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IGX0	Leptomonas seymouri	47%	94%
A0A3Q8IGF6	Leishmania donovani	61%	96%
A4HJX3	Leishmania braziliensis	100%	100%
A4I6W9	Leishmania infantum	62%	96%
E9B1Z3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	96%
Q4Q668	Leishmania major	59%	100%