LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4HJG7_LEIBR
TriTrypDb:
LbrM.31.2080 , LBRM2903_310030000 *
Length:
1343

Annotations

LeishMANIAdb annotations

A typical Kinetoplastid receptor kinase, belonging to the STE11 kinase family (MAP3K). Very tentatively required for stress response and / or developmental stage regulation. Expanded in many kinetoplastid groups, but especially in Leishmaniids.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 13
NetGPI no yes: 0, no: 14
Cellular components
Term Name Level Count
GO:0016020 membrane 2 12
GO:0110165 cellular anatomical entity 1 12

Expansion

Sequence features

A4HJG7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 14
GO:0006793 phosphorus metabolic process 3 15
GO:0006796 phosphate-containing compound metabolic process 4 15
GO:0006807 nitrogen compound metabolic process 2 14
GO:0008152 metabolic process 1 15
GO:0009987 cellular process 1 15
GO:0016310 phosphorylation 5 15
GO:0019538 protein metabolic process 3 14
GO:0036211 protein modification process 4 14
GO:0043170 macromolecule metabolic process 3 14
GO:0043412 macromolecule modification 4 14
GO:0044237 cellular metabolic process 2 15
GO:0044238 primary metabolic process 2 14
GO:0071704 organic substance metabolic process 2 14
GO:1901564 organonitrogen compound metabolic process 3 14
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 14
GO:0003824 catalytic activity 1 15
GO:0004672 protein kinase activity 3 15
GO:0005488 binding 1 14
GO:0005524 ATP binding 5 14
GO:0016301 kinase activity 4 15
GO:0016740 transferase activity 2 15
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 15
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 15
GO:0017076 purine nucleotide binding 4 14
GO:0030554 adenyl nucleotide binding 5 14
GO:0032553 ribonucleotide binding 3 14
GO:0032555 purine ribonucleotide binding 4 14
GO:0032559 adenyl ribonucleotide binding 5 14
GO:0035639 purine ribonucleoside triphosphate binding 4 14
GO:0036094 small molecule binding 2 14
GO:0043167 ion binding 2 14
GO:0043168 anion binding 3 14
GO:0097159 organic cyclic compound binding 2 14
GO:0097367 carbohydrate derivative binding 2 14
GO:0140096 catalytic activity, acting on a protein 2 15
GO:1901265 nucleoside phosphate binding 3 14
GO:1901363 heterocyclic compound binding 2 14
GO:0004674 protein serine/threonine kinase activity 4 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1068 1072 PF00656 0.537
CLV_C14_Caspase3-7 173 177 PF00656 0.272
CLV_C14_Caspase3-7 707 711 PF00656 0.521
CLV_NRD_NRD_1 1026 1028 PF00675 0.388
CLV_NRD_NRD_1 517 519 PF00675 0.467
CLV_NRD_NRD_1 535 537 PF00675 0.426
CLV_NRD_NRD_1 696 698 PF00675 0.355
CLV_NRD_NRD_1 792 794 PF00675 0.312
CLV_NRD_NRD_1 885 887 PF00675 0.560
CLV_PCSK_FUR_1 533 537 PF00082 0.381
CLV_PCSK_KEX2_1 1026 1028 PF00082 0.307
CLV_PCSK_KEX2_1 1316 1318 PF00082 0.257
CLV_PCSK_KEX2_1 41 43 PF00082 0.326
CLV_PCSK_KEX2_1 517 519 PF00082 0.438
CLV_PCSK_KEX2_1 533 535 PF00082 0.400
CLV_PCSK_KEX2_1 696 698 PF00082 0.351
CLV_PCSK_KEX2_1 791 793 PF00082 0.315
CLV_PCSK_KEX2_1 885 887 PF00082 0.560
CLV_PCSK_KEX2_1 937 939 PF00082 0.390
CLV_PCSK_PC1ET2_1 1316 1318 PF00082 0.212
CLV_PCSK_PC1ET2_1 41 43 PF00082 0.326
CLV_PCSK_PC1ET2_1 937 939 PF00082 0.342
CLV_PCSK_PC7_1 787 793 PF00082 0.320
CLV_PCSK_SKI1_1 1004 1008 PF00082 0.348
CLV_PCSK_SKI1_1 1082 1086 PF00082 0.577
CLV_PCSK_SKI1_1 1099 1103 PF00082 0.271
CLV_PCSK_SKI1_1 1140 1144 PF00082 0.387
CLV_PCSK_SKI1_1 1328 1332 PF00082 0.452
CLV_PCSK_SKI1_1 302 306 PF00082 0.619
CLV_PCSK_SKI1_1 356 360 PF00082 0.561
CLV_PCSK_SKI1_1 38 42 PF00082 0.372
CLV_PCSK_SKI1_1 528 532 PF00082 0.430
CLV_PCSK_SKI1_1 536 540 PF00082 0.362
CLV_PCSK_SKI1_1 961 965 PF00082 0.323
CLV_PCSK_SKI1_1 999 1003 PF00082 0.374
DEG_APCC_DBOX_1 1155 1163 PF00400 0.537
DEG_APCC_DBOX_1 355 363 PF00400 0.459
DEG_Nend_UBRbox_2 1 3 PF02207 0.543
DEG_ODPH_VHL_1 270 282 PF01847 0.276
DEG_SCF_FBW7_1 311 317 PF00400 0.306
DEG_SCF_FBW7_1 333 339 PF00400 0.252
DEG_SCF_FBW7_1 553 560 PF00400 0.532
DEG_SPOP_SBC_1 371 375 PF00917 0.296
DOC_ANK_TNKS_1 1025 1032 PF00023 0.482
DOC_ANK_TNKS_1 1069 1076 PF00023 0.737
DOC_CDC14_PxL_1 1256 1264 PF14671 0.412
DOC_CKS1_1 1221 1226 PF01111 0.618
DOC_CKS1_1 1289 1294 PF01111 0.475
DOC_CKS1_1 311 316 PF01111 0.301
DOC_CKS1_1 333 338 PF01111 0.303
DOC_CKS1_1 606 611 PF01111 0.754
DOC_CYCLIN_RxL_1 1324 1333 PF00134 0.520
DOC_CYCLIN_yClb5_NLxxxL_5 927 935 PF00134 0.524
DOC_CYCLIN_yCln2_LP_2 398 404 PF00134 0.455
DOC_CYCLIN_yCln2_LP_2 879 882 PF00134 0.631
DOC_MAPK_gen_1 1012 1020 PF00069 0.516
DOC_MAPK_gen_1 1316 1323 PF00069 0.412
DOC_MAPK_gen_1 534 545 PF00069 0.595
DOC_MAPK_MEF2A_6 1324 1331 PF00069 0.519
DOC_MAPK_MEF2A_6 298 307 PF00069 0.411
DOC_MAPK_MEF2A_6 539 547 PF00069 0.566
DOC_MAPK_MEF2A_6 767 776 PF00069 0.688
DOC_MAPK_MEF2A_6 89 97 PF00069 0.247
DOC_PP1_RVXF_1 472 479 PF00149 0.508
DOC_PP1_RVXF_1 910 916 PF00149 0.497
DOC_PP2B_LxvP_1 398 401 PF13499 0.452
DOC_PP2B_LxvP_1 681 684 PF13499 0.636
DOC_PP2B_LxvP_1 879 882 PF13499 0.631
DOC_PP4_FxxP_1 1204 1207 PF00568 0.515
DOC_PP4_FxxP_1 1289 1292 PF00568 0.475
DOC_PP4_FxxP_1 201 204 PF00568 0.390
DOC_PP4_FxxP_1 606 609 PF00568 0.762
DOC_USP7_MATH_1 1043 1047 PF00917 0.651
DOC_USP7_MATH_1 1051 1055 PF00917 0.552
DOC_USP7_MATH_1 470 474 PF00917 0.509
DOC_USP7_MATH_1 523 527 PF00917 0.667
DOC_USP7_MATH_1 557 561 PF00917 0.700
DOC_USP7_MATH_1 746 750 PF00917 0.701
DOC_USP7_MATH_1 888 892 PF00917 0.702
DOC_WW_Pin1_4 1082 1087 PF00397 0.771
DOC_WW_Pin1_4 1088 1093 PF00397 0.645
DOC_WW_Pin1_4 1131 1136 PF00397 0.537
DOC_WW_Pin1_4 1210 1215 PF00397 0.618
DOC_WW_Pin1_4 1220 1225 PF00397 0.509
DOC_WW_Pin1_4 1288 1293 PF00397 0.475
DOC_WW_Pin1_4 1310 1315 PF00397 0.449
DOC_WW_Pin1_4 310 315 PF00397 0.295
DOC_WW_Pin1_4 332 337 PF00397 0.308
DOC_WW_Pin1_4 518 523 PF00397 0.614
DOC_WW_Pin1_4 553 558 PF00397 0.554
DOC_WW_Pin1_4 564 569 PF00397 0.706
DOC_WW_Pin1_4 605 610 PF00397 0.763
DOC_WW_Pin1_4 655 660 PF00397 0.615
DOC_WW_Pin1_4 722 727 PF00397 0.614
LIG_14-3-3_CanoR_1 1303 1307 PF00244 0.561
LIG_14-3-3_CanoR_1 233 240 PF00244 0.331
LIG_14-3-3_CanoR_1 775 785 PF00244 0.627
LIG_14-3-3_CanoR_1 914 920 PF00244 0.594
LIG_14-3-3_CanoR_1 923 931 PF00244 0.572
LIG_14-3-3_CanoR_1 961 970 PF00244 0.550
LIG_14-3-3_CanoR_1 999 1004 PF00244 0.530
LIG_Actin_WH2_2 797 815 PF00022 0.600
LIG_Actin_WH2_2 989 1006 PF00022 0.493
LIG_BIR_III_2 1071 1075 PF00653 0.677
LIG_BIR_III_4 710 714 PF00653 0.516
LIG_BRCT_BRCA1_1 1045 1049 PF00533 0.490
LIG_BRCT_BRCA1_1 1051 1055 PF00533 0.465
LIG_BRCT_BRCA1_1 569 573 PF00533 0.633
LIG_BRCT_BRCA1_1 602 606 PF00533 0.800
LIG_BRCT_BRCA1_1 978 982 PF00533 0.496
LIG_Clathr_ClatBox_1 1233 1237 PF01394 0.493
LIG_Clathr_ClatBox_1 255 259 PF01394 0.268
LIG_Clathr_ClatBox_1 806 810 PF01394 0.495
LIG_CtBP_PxDLS_1 503 507 PF00389 0.527
LIG_CtBP_PxDLS_1 881 885 PF00389 0.557
LIG_CtBP_PxDLS_1 928 932 PF00389 0.523
LIG_deltaCOP1_diTrp_1 1242 1247 PF00928 0.412
LIG_deltaCOP1_diTrp_1 53 61 PF00928 0.436
LIG_EVH1_1 1221 1225 PF00568 0.462
LIG_FHA_1 10 16 PF00498 0.489
LIG_FHA_1 1180 1186 PF00498 0.475
LIG_FHA_1 1216 1222 PF00498 0.499
LIG_FHA_1 149 155 PF00498 0.243
LIG_FHA_1 173 179 PF00498 0.380
LIG_FHA_1 189 195 PF00498 0.393
LIG_FHA_1 275 281 PF00498 0.360
LIG_FHA_1 333 339 PF00498 0.395
LIG_FHA_1 410 416 PF00498 0.352
LIG_FHA_1 427 433 PF00498 0.235
LIG_FHA_1 553 559 PF00498 0.534
LIG_FHA_1 611 617 PF00498 0.646
LIG_FHA_1 69 75 PF00498 0.349
LIG_FHA_1 750 756 PF00498 0.724
LIG_FHA_1 780 786 PF00498 0.644
LIG_FHA_1 916 922 PF00498 0.627
LIG_FHA_1 924 930 PF00498 0.581
LIG_FHA_2 1055 1061 PF00498 0.463
LIG_FHA_2 1066 1072 PF00498 0.526
LIG_FHA_2 1136 1142 PF00498 0.537
LIG_FHA_2 1246 1252 PF00498 0.609
LIG_FHA_2 1256 1262 PF00498 0.463
LIG_FHA_2 1317 1323 PF00498 0.511
LIG_FHA_2 139 145 PF00498 0.234
LIG_FHA_2 156 162 PF00498 0.215
LIG_FHA_2 168 174 PF00498 0.251
LIG_FHA_2 273 279 PF00498 0.265
LIG_FHA_2 953 959 PF00498 0.604
LIG_GBD_Chelix_1 303 311 PF00786 0.572
LIG_Integrin_RGD_1 856 858 PF01839 0.388
LIG_IRF3_LxIS_1 303 308 PF10401 0.310
LIG_LIR_Apic_2 1209 1214 PF02991 0.618
LIG_LIR_Apic_2 1287 1292 PF02991 0.475
LIG_LIR_Apic_2 198 204 PF02991 0.352
LIG_LIR_Apic_2 265 269 PF02991 0.306
LIG_LIR_Apic_2 516 522 PF02991 0.675
LIG_LIR_Apic_2 603 609 PF02991 0.779
LIG_LIR_Gen_1 1296 1306 PF02991 0.475
LIG_LIR_Gen_1 144 154 PF02991 0.288
LIG_LIR_Gen_1 276 286 PF02991 0.387
LIG_LIR_Gen_1 343 350 PF02991 0.286
LIG_LIR_Gen_1 480 487 PF02991 0.475
LIG_LIR_Gen_1 53 64 PF02991 0.512
LIG_LIR_Gen_1 849 859 PF02991 0.637
LIG_LIR_Gen_1 85 95 PF02991 0.284
LIG_LIR_Nem_3 1052 1058 PF02991 0.644
LIG_LIR_Nem_3 1296 1301 PF02991 0.475
LIG_LIR_Nem_3 141 146 PF02991 0.291
LIG_LIR_Nem_3 147 152 PF02991 0.272
LIG_LIR_Nem_3 276 282 PF02991 0.384
LIG_LIR_Nem_3 331 337 PF02991 0.322
LIG_LIR_Nem_3 343 347 PF02991 0.272
LIG_LIR_Nem_3 434 440 PF02991 0.410
LIG_LIR_Nem_3 455 460 PF02991 0.559
LIG_LIR_Nem_3 480 484 PF02991 0.470
LIG_LIR_Nem_3 53 59 PF02991 0.512
LIG_LIR_Nem_3 837 843 PF02991 0.592
LIG_LIR_Nem_3 85 90 PF02991 0.392
LIG_LIR_Nem_3 979 985 PF02991 0.545
LIG_LYPXL_SIV_4 109 117 PF13949 0.244
LIG_LYPXL_yS_3 123 126 PF13949 0.239
LIG_LYPXL_yS_3 985 988 PF13949 0.619
LIG_MYND_1 877 881 PF01753 0.751
LIG_NRBOX 1138 1144 PF00104 0.556
LIG_NRBOX 135 141 PF00104 0.314
LIG_PCNA_yPIPBox_3 999 1007 PF02747 0.534
LIG_PDZ_Class_3 1338 1343 PF00595 0.556
LIG_Pex14_1 56 60 PF04695 0.436
LIG_Pex14_2 61 65 PF04695 0.319
LIG_PTAP_UEV_1 1007 1012 PF05743 0.532
LIG_Rb_LxCxE_1 1332 1343 PF01857 0.530
LIG_REV1ctd_RIR_1 1053 1062 PF16727 0.427
LIG_RPA_C_Fungi 691 703 PF08784 0.541
LIG_SH2_CRK 1105 1109 PF00017 0.235
LIG_SH2_CRK 1146 1150 PF00017 0.305
LIG_SH2_CRK 1211 1215 PF00017 0.235
LIG_SH2_CRK 1231 1235 PF00017 0.296
LIG_SH2_CRK 334 338 PF00017 0.353
LIG_SH2_CRK 519 523 PF00017 0.515
LIG_SH2_CRK 866 870 PF00017 0.509
LIG_SH2_GRB2like 283 286 PF00017 0.311
LIG_SH2_NCK_1 519 523 PF00017 0.515
LIG_SH2_PTP2 279 282 PF00017 0.297
LIG_SH2_PTP2 361 364 PF00017 0.278
LIG_SH2_SRC 283 286 PF00017 0.364
LIG_SH2_SRC 439 442 PF00017 0.235
LIG_SH2_STAP1 1119 1123 PF00017 0.357
LIG_SH2_STAP1 1298 1302 PF00017 0.375
LIG_SH2_STAT3 199 202 PF00017 0.359
LIG_SH2_STAT5 1107 1110 PF00017 0.217
LIG_SH2_STAT5 146 149 PF00017 0.245
LIG_SH2_STAT5 181 184 PF00017 0.536
LIG_SH2_STAT5 193 196 PF00017 0.465
LIG_SH2_STAT5 279 282 PF00017 0.472
LIG_SH2_STAT5 283 286 PF00017 0.350
LIG_SH2_STAT5 334 337 PF00017 0.418
LIG_SH2_STAT5 344 347 PF00017 0.560
LIG_SH2_STAT5 361 364 PF00017 0.291
LIG_SH2_STAT5 439 442 PF00017 0.320
LIG_SH2_STAT5 45 48 PF00017 0.352
LIG_SH2_STAT5 552 555 PF00017 0.550
LIG_SH2_STAT5 744 747 PF00017 0.342
LIG_SH2_STAT5 995 998 PF00017 0.399
LIG_SH3_1 1070 1076 PF00018 0.692
LIG_SH3_1 247 253 PF00018 0.402
LIG_SH3_1 266 272 PF00018 0.310
LIG_SH3_3 1005 1011 PF00018 0.594
LIG_SH3_3 1070 1076 PF00018 0.692
LIG_SH3_3 1084 1090 PF00018 0.481
LIG_SH3_3 118 124 PF00018 0.248
LIG_SH3_3 1219 1225 PF00018 0.287
LIG_SH3_3 247 253 PF00018 0.402
LIG_SH3_3 266 272 PF00018 0.310
LIG_SH3_3 347 353 PF00018 0.477
LIG_SH3_3 442 448 PF00018 0.252
LIG_SUMO_SIM_anti_2 1261 1267 PF11976 0.284
LIG_SUMO_SIM_anti_2 429 434 PF11976 0.235
LIG_SUMO_SIM_anti_2 820 828 PF11976 0.498
LIG_SUMO_SIM_par_1 1126 1132 PF11976 0.436
LIG_SUMO_SIM_par_1 1181 1188 PF11976 0.305
LIG_SUMO_SIM_par_1 1232 1237 PF11976 0.217
LIG_SUMO_SIM_par_1 150 156 PF11976 0.425
LIG_SUMO_SIM_par_1 428 434 PF11976 0.428
LIG_SUMO_SIM_par_1 820 828 PF11976 0.498
LIG_TRAF2_1 1092 1095 PF00917 0.393
LIG_TRAF2_1 1337 1340 PF00917 0.577
LIG_TRAF2_1 158 161 PF00917 0.249
LIG_TRAF2_1 618 621 PF00917 0.364
LIG_TRAF2_1 683 686 PF00917 0.730
LIG_TYR_ITIM 1103 1108 PF00017 0.231
LIG_TYR_ITIM 121 126 PF00017 0.253
LIG_TYR_ITIM 342 347 PF00017 0.285
LIG_TYR_ITIM 359 364 PF00017 0.247
LIG_TYR_ITIM 825 830 PF00017 0.582
LIG_WRC_WIRS_1 1055 1060 PF05994 0.287
LIG_WRC_WIRS_1 146 151 PF05994 0.268
LIG_WW_1 27 30 PF00397 0.392
LIG_WW_3 35 39 PF00397 0.309
MOD_CDK_SPxK_1 1310 1316 PF00069 0.217
MOD_CDK_SPxxK_3 1310 1317 PF00069 0.269
MOD_CDK_SPxxK_3 518 525 PF00069 0.502
MOD_CK1_1 1054 1060 PF00069 0.287
MOD_CK1_1 1163 1169 PF00069 0.418
MOD_CK1_1 1187 1193 PF00069 0.305
MOD_CK1_1 129 135 PF00069 0.475
MOD_CK1_1 148 154 PF00069 0.296
MOD_CK1_1 174 180 PF00069 0.366
MOD_CK1_1 18 24 PF00069 0.415
MOD_CK1_1 232 238 PF00069 0.481
MOD_CK1_1 310 316 PF00069 0.343
MOD_CK1_1 372 378 PF00069 0.419
MOD_CK1_1 406 412 PF00069 0.316
MOD_CK1_1 513 519 PF00069 0.546
MOD_CK1_1 560 566 PF00069 0.710
MOD_CK1_1 567 573 PF00069 0.628
MOD_CK1_1 715 721 PF00069 0.503
MOD_CK1_1 72 78 PF00069 0.403
MOD_CK1_1 737 743 PF00069 0.611
MOD_CK1_1 749 755 PF00069 0.454
MOD_CK1_1 891 897 PF00069 0.713
MOD_CK2_1 1135 1141 PF00069 0.392
MOD_CK2_1 1245 1251 PF00069 0.382
MOD_CK2_1 1316 1322 PF00069 0.366
MOD_CK2_1 155 161 PF00069 0.250
MOD_CK2_1 167 173 PF00069 0.274
MOD_CK2_1 18 24 PF00069 0.353
MOD_CK2_1 371 377 PF00069 0.338
MOD_CK2_1 948 954 PF00069 0.532
MOD_DYRK1A_RPxSP_1 1082 1086 PF00069 0.612
MOD_GlcNHglycan 1008 1011 PF01048 0.388
MOD_GlcNHglycan 1045 1048 PF01048 0.518
MOD_GlcNHglycan 106 109 PF01048 0.306
MOD_GlcNHglycan 1082 1085 PF01048 0.616
MOD_GlcNHglycan 1162 1165 PF01048 0.418
MOD_GlcNHglycan 394 397 PF01048 0.251
MOD_GlcNHglycan 449 452 PF01048 0.305
MOD_GlcNHglycan 602 605 PF01048 0.723
MOD_GlcNHglycan 643 646 PF01048 0.526
MOD_GlcNHglycan 714 717 PF01048 0.555
MOD_GlcNHglycan 890 893 PF01048 0.673
MOD_GSK3_1 1 8 PF00069 0.365
MOD_GSK3_1 1131 1138 PF00069 0.392
MOD_GSK3_1 1206 1213 PF00069 0.506
MOD_GSK3_1 1308 1315 PF00069 0.274
MOD_GSK3_1 144 151 PF00069 0.245
MOD_GSK3_1 167 174 PF00069 0.419
MOD_GSK3_1 18 25 PF00069 0.426
MOD_GSK3_1 180 187 PF00069 0.545
MOD_GSK3_1 232 239 PF00069 0.415
MOD_GSK3_1 310 317 PF00069 0.354
MOD_GSK3_1 324 331 PF00069 0.399
MOD_GSK3_1 332 339 PF00069 0.442
MOD_GSK3_1 388 395 PF00069 0.366
MOD_GSK3_1 403 410 PF00069 0.265
MOD_GSK3_1 443 450 PF00069 0.276
MOD_GSK3_1 452 459 PF00069 0.382
MOD_GSK3_1 524 531 PF00069 0.591
MOD_GSK3_1 541 548 PF00069 0.446
MOD_GSK3_1 553 560 PF00069 0.481
MOD_GSK3_1 563 570 PF00069 0.638
MOD_GSK3_1 610 617 PF00069 0.589
MOD_GSK3_1 622 629 PF00069 0.531
MOD_GSK3_1 68 75 PF00069 0.446
MOD_GSK3_1 733 740 PF00069 0.589
MOD_GSK3_1 929 936 PF00069 0.484
MOD_GSK3_1 948 955 PF00069 0.500
MOD_GSK3_1 96 103 PF00069 0.303
MOD_GSK3_1 976 983 PF00069 0.367
MOD_N-GLC_1 184 189 PF02516 0.546
MOD_N-GLC_1 216 221 PF02516 0.522
MOD_N-GLC_1 222 227 PF02516 0.493
MOD_N-GLC_1 284 289 PF02516 0.458
MOD_N-GLC_1 329 334 PF02516 0.436
MOD_N-GLC_1 340 345 PF02516 0.446
MOD_N-GLC_1 488 493 PF02516 0.425
MOD_N-GLC_1 5 10 PF02516 0.294
MOD_N-GLC_1 929 934 PF02516 0.411
MOD_N-GLC_1 95 100 PF02516 0.276
MOD_NEK2_1 1049 1054 PF00069 0.323
MOD_NEK2_1 1077 1082 PF00069 0.437
MOD_NEK2_1 1301 1306 PF00069 0.305
MOD_NEK2_1 152 157 PF00069 0.310
MOD_NEK2_1 305 310 PF00069 0.397
MOD_NEK2_1 329 334 PF00069 0.459
MOD_NEK2_1 337 342 PF00069 0.301
MOD_NEK2_1 407 412 PF00069 0.449
MOD_NEK2_1 431 436 PF00069 0.398
MOD_NEK2_1 456 461 PF00069 0.516
MOD_NEK2_1 5 10 PF00069 0.446
MOD_NEK2_1 538 543 PF00069 0.457
MOD_NEK2_1 545 550 PF00069 0.387
MOD_NEK2_1 622 627 PF00069 0.657
MOD_NEK2_1 63 68 PF00069 0.310
MOD_NEK2_1 69 74 PF00069 0.304
MOD_NEK2_1 733 738 PF00069 0.618
MOD_NEK2_1 78 83 PF00069 0.310
MOD_NEK2_1 921 926 PF00069 0.364
MOD_NEK2_1 929 934 PF00069 0.424
MOD_NEK2_2 1051 1056 PF00069 0.247
MOD_NEK2_2 1135 1140 PF00069 0.506
MOD_NEK2_2 1302 1307 PF00069 0.305
MOD_PIKK_1 100 106 PF00454 0.264
MOD_PIKK_1 1090 1096 PF00454 0.313
MOD_PIKK_1 293 299 PF00454 0.392
MOD_PIKK_1 30 36 PF00454 0.366
MOD_PIKK_1 305 311 PF00454 0.318
MOD_PIKK_1 72 78 PF00454 0.417
MOD_PIKK_1 929 935 PF00454 0.381
MOD_PKA_1 1316 1322 PF00069 0.217
MOD_PKA_1 791 797 PF00069 0.355
MOD_PKA_1 937 943 PF00069 0.427
MOD_PKA_2 1245 1251 PF00069 0.303
MOD_PKA_2 1302 1308 PF00069 0.365
MOD_PKA_2 1316 1322 PF00069 0.432
MOD_PKA_2 232 238 PF00069 0.398
MOD_PKA_2 508 514 PF00069 0.600
MOD_PKA_2 524 530 PF00069 0.551
MOD_PKA_2 791 797 PF00069 0.355
MOD_PKA_2 915 921 PF00069 0.514
MOD_PKA_2 922 928 PF00069 0.452
MOD_PKA_2 937 943 PF00069 0.493
MOD_PKA_2 976 982 PF00069 0.468
MOD_Plk_1 129 135 PF00069 0.459
MOD_Plk_1 184 190 PF00069 0.493
MOD_Plk_1 216 222 PF00069 0.283
MOD_Plk_1 223 229 PF00069 0.340
MOD_Plk_1 284 290 PF00069 0.392
MOD_Plk_1 329 335 PF00069 0.428
MOD_Plk_1 340 346 PF00069 0.379
MOD_Plk_1 362 368 PF00069 0.389
MOD_Plk_1 488 494 PF00069 0.427
MOD_Plk_1 5 11 PF00069 0.295
MOD_Plk_1 684 690 PF00069 0.504
MOD_Plk_1 734 740 PF00069 0.612
MOD_Plk_1 749 755 PF00069 0.405
MOD_Plk_1 929 935 PF00069 0.381
MOD_Plk_1 989 995 PF00069 0.330
MOD_Plk_2-3 704 710 PF00069 0.329
MOD_Plk_4 1051 1057 PF00069 0.236
MOD_Plk_4 1163 1169 PF00069 0.392
MOD_Plk_4 1179 1185 PF00069 0.238
MOD_Plk_4 188 194 PF00069 0.487
MOD_Plk_4 217 223 PF00069 0.298
MOD_Plk_4 314 320 PF00069 0.500
MOD_Plk_4 324 330 PF00069 0.461
MOD_Plk_4 340 346 PF00069 0.370
MOD_Plk_4 433 439 PF00069 0.353
MOD_Plk_4 452 458 PF00069 0.511
MOD_Plk_4 5 11 PF00069 0.328
MOD_Plk_4 546 552 PF00069 0.526
MOD_Plk_4 69 75 PF00069 0.295
MOD_Plk_4 704 710 PF00069 0.442
MOD_Plk_4 734 740 PF00069 0.612
MOD_Plk_4 781 787 PF00069 0.536
MOD_ProDKin_1 1082 1088 PF00069 0.713
MOD_ProDKin_1 1131 1137 PF00069 0.392
MOD_ProDKin_1 1210 1216 PF00069 0.506
MOD_ProDKin_1 1220 1226 PF00069 0.352
MOD_ProDKin_1 1288 1294 PF00069 0.305
MOD_ProDKin_1 1310 1316 PF00069 0.269
MOD_ProDKin_1 310 316 PF00069 0.339
MOD_ProDKin_1 332 338 PF00069 0.348
MOD_ProDKin_1 518 524 PF00069 0.500
MOD_ProDKin_1 553 559 PF00069 0.422
MOD_ProDKin_1 564 570 PF00069 0.630
MOD_ProDKin_1 605 611 PF00069 0.703
MOD_ProDKin_1 655 661 PF00069 0.502
MOD_ProDKin_1 722 728 PF00069 0.494
TRG_DiLeu_BaEn_1 480 485 PF01217 0.476
TRG_DiLeu_BaEn_1 781 786 PF01217 0.523
TRG_DiLeu_BaEn_2 1199 1205 PF01217 0.217
TRG_DiLeu_BaEn_4 575 581 PF01217 0.475
TRG_DiLeu_BaLyEn_6 285 290 PF01217 0.420
TRG_DiLeu_BaLyEn_6 333 338 PF01217 0.275
TRG_DiLeu_BaLyEn_6 398 403 PF01217 0.268
TRG_DiLeu_BaLyEn_6 583 588 PF01217 0.537
TRG_DiLeu_BaLyEn_6 802 807 PF01217 0.328
TRG_ENDOCYTIC_2 1021 1024 PF00928 0.426
TRG_ENDOCYTIC_2 1105 1108 PF00928 0.235
TRG_ENDOCYTIC_2 1146 1149 PF00928 0.506
TRG_ENDOCYTIC_2 123 126 PF00928 0.255
TRG_ENDOCYTIC_2 1231 1234 PF00928 0.331
TRG_ENDOCYTIC_2 1298 1301 PF00928 0.305
TRG_ENDOCYTIC_2 146 149 PF00928 0.415
TRG_ENDOCYTIC_2 279 282 PF00928 0.493
TRG_ENDOCYTIC_2 334 337 PF00928 0.362
TRG_ENDOCYTIC_2 344 347 PF00928 0.315
TRG_ENDOCYTIC_2 361 364 PF00928 0.248
TRG_ENDOCYTIC_2 404 407 PF00928 0.446
TRG_ENDOCYTIC_2 45 48 PF00928 0.309
TRG_ENDOCYTIC_2 827 830 PF00928 0.578
TRG_ENDOCYTIC_2 866 869 PF00928 0.508
TRG_ENDOCYTIC_2 985 988 PF00928 0.542
TRG_ER_diArg_1 506 509 PF00400 0.473
TRG_ER_diArg_1 517 519 PF00400 0.496
TRG_ER_diArg_1 533 536 PF00400 0.474
TRG_ER_diArg_1 790 793 PF00400 0.363
TRG_ER_diArg_1 884 886 PF00400 0.699
TRG_ER_diArg_1 912 915 PF00400 0.517
TRG_ER_diArg_1 967 970 PF00400 0.539
TRG_NLS_MonoExtN_4 533 540 PF00514 0.433
TRG_Pf-PMV_PEXEL_1 1012 1016 PF00026 0.347
TRG_Pf-PMV_PEXEL_1 288 292 PF00026 0.525

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IG80 Leishmania donovani 61% 98%
A0A3S7WQ86 Leishmania donovani 44% 99%
A0A3S7X4L0 Leishmania donovani 59% 99%
A4HJG2 Leishmania braziliensis 88% 100%
A4HTL4 Leishmania infantum 44% 99%
A4I6V7 Leishmania infantum 61% 98%
A4I6V8 Leishmania infantum 58% 99%
E9AME5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 43% 100%
E9B1Y1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 60% 98%
E9B1Y2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 58% 99%
Q4Q678 Leishmania major 57% 100%
Q4Q679 Leishmania major 60% 99%
Q4QIA3 Leishmania major 44% 97%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS