GP46-like surface antigen

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJC6_LEIBR

TriTrypDb:

LbrM.31.1660 , LBRM2903_200078600 , LBRM2903_310025900

Length:

556

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	2
GO:0042995	cell projection	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0120025	plasma membrane bounded cell projection	3	2

Expansion

Sequence features

A4HJC6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJC6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	147	149	PF00675	0.542
CLV_PCSK_KEX2_1	525	527	PF00082	0.577
CLV_PCSK_PC1ET2_1	525	527	PF00082	0.577
CLV_PCSK_SKI1_1	117	121	PF00082	0.497
DEG_Nend_UBRbox_1	1	4	PF02207	0.800
DEG_SPOP_SBC_1	159	163	PF00917	0.834
DEG_SPOP_SBC_1	169	173	PF00917	0.751
DEG_SPOP_SBC_1	179	183	PF00917	0.634
DEG_SPOP_SBC_1	189	193	PF00917	0.629
DEG_SPOP_SBC_1	199	203	PF00917	0.633
DEG_SPOP_SBC_1	209	213	PF00917	0.632
DEG_SPOP_SBC_1	221	225	PF00917	0.732
DEG_SPOP_SBC_1	233	237	PF00917	0.735
DEG_SPOP_SBC_1	240	244	PF00917	0.647
DEG_SPOP_SBC_1	252	256	PF00917	0.649
DEG_SPOP_SBC_1	265	269	PF00917	0.727
DEG_SPOP_SBC_1	276	280	PF00917	0.744
DEG_SPOP_SBC_1	289	293	PF00917	0.728
DEG_SPOP_SBC_1	300	304	PF00917	0.753
DEG_SPOP_SBC_1	308	312	PF00917	0.652
DEG_SPOP_SBC_1	319	323	PF00917	0.646
DEG_SPOP_SBC_1	326	330	PF00917	0.662
DEG_SPOP_SBC_1	339	343	PF00917	0.641
DEG_SPOP_SBC_1	350	354	PF00917	0.750
DEG_SPOP_SBC_1	363	367	PF00917	0.729
DEG_SPOP_SBC_1	374	378	PF00917	0.749
DEG_SPOP_SBC_1	381	385	PF00917	0.663
DEG_SPOP_SBC_1	393	397	PF00917	0.652
DEG_SPOP_SBC_1	406	410	PF00917	0.726
DEG_SPOP_SBC_1	417	421	PF00917	0.746
DEG_SPOP_SBC_1	430	434	PF00917	0.726
DEG_SPOP_SBC_1	441	445	PF00917	0.752
DEG_SPOP_SBC_1	449	453	PF00917	0.653
DEG_SPOP_SBC_1	460	464	PF00917	0.648
DEG_SPOP_SBC_1	47	51	PF00917	0.683
DEG_SPOP_SBC_1	472	476	PF00917	0.733
DOC_CYCLIN_yCln2_LP_2	101	107	PF00134	0.707
DOC_USP7_MATH_1	189	193	PF00917	0.879
DOC_USP7_MATH_1	240	244	PF00917	0.884
DOC_USP7_MATH_1	25	29	PF00917	0.689
DOC_USP7_MATH_1	252	256	PF00917	0.736
DOC_USP7_MATH_1	264	268	PF00917	0.735
DOC_USP7_MATH_1	307	311	PF00917	0.887
DOC_USP7_MATH_1	326	330	PF00917	0.650
DOC_USP7_MATH_1	338	342	PF00917	0.737
DOC_USP7_MATH_1	38	42	PF00917	0.530
DOC_USP7_MATH_1	381	385	PF00917	0.888
DOC_USP7_MATH_1	393	397	PF00917	0.739
DOC_USP7_MATH_1	405	409	PF00917	0.735
DOC_USP7_MATH_1	448	452	PF00917	0.884
DOC_USP7_MATH_1	47	51	PF00917	0.570
DOC_USP7_MATH_1	472	476	PF00917	0.883
DOC_USP7_MATH_1	502	506	PF00917	0.754
DOC_USP7_MATH_1	542	546	PF00917	0.549
DOC_USP7_MATH_1	60	64	PF00917	0.532
DOC_WW_Pin1_4	153	158	PF00397	0.762
DOC_WW_Pin1_4	475	480	PF00397	0.884
DOC_WW_Pin1_4	485	490	PF00397	0.719
LIG_14-3-3_CanoR_1	484	489	PF00244	0.853
LIG_14-3-3_CanoR_1	507	515	PF00244	0.726
LIG_Clathr_ClatBox_1	140	144	PF01394	0.714
LIG_FHA_1	135	141	PF00498	0.742
LIG_FHA_1	4	10	PF00498	0.735
LIG_FHA_1	72	78	PF00498	0.704
LIG_FHA_2	163	169	PF00498	0.866
LIG_FHA_2	173	179	PF00498	0.756
LIG_FHA_2	183	189	PF00498	0.632
LIG_FHA_2	193	199	PF00498	0.633
LIG_FHA_2	203	209	PF00498	0.632
LIG_FHA_2	215	221	PF00498	0.728
LIG_FHA_2	227	233	PF00498	0.737
LIG_FHA_2	234	240	PF00498	0.646
LIG_FHA_2	246	252	PF00498	0.647
LIG_FHA_2	258	264	PF00498	0.741
LIG_FHA_2	270	276	PF00498	0.736
LIG_FHA_2	282	288	PF00498	0.741
LIG_FHA_2	294	300	PF00498	0.747
LIG_FHA_2	301	307	PF00498	0.652
LIG_FHA_2	313	319	PF00498	0.655
LIG_FHA_2	320	326	PF00498	0.647
LIG_FHA_2	332	338	PF00498	0.655
LIG_FHA_2	344	350	PF00498	0.744
LIG_FHA_2	356	362	PF00498	0.741
LIG_FHA_2	368	374	PF00498	0.745
LIG_FHA_2	375	381	PF00498	0.648
LIG_FHA_2	387	393	PF00498	0.652
LIG_FHA_2	399	405	PF00498	0.742
LIG_FHA_2	411	417	PF00498	0.740
LIG_FHA_2	423	429	PF00498	0.741
LIG_FHA_2	435	441	PF00498	0.744
LIG_FHA_2	442	448	PF00498	0.650
LIG_FHA_2	454	460	PF00498	0.651
LIG_FHA_2	466	472	PF00498	0.738
LIG_FHA_2	78	84	PF00498	0.721
LIG_LIR_Gen_1	108	115	PF02991	0.718
LIG_LIR_Gen_1	36	43	PF02991	0.686
LIG_LIR_Gen_1	83	91	PF02991	0.723
LIG_LIR_Nem_3	11	16	PF02991	0.716
LIG_MYND_3	112	116	PF01753	0.720
LIG_MYND_3	64	68	PF01753	0.691
LIG_Pex14_2	105	109	PF04695	0.703
LIG_PTB_Apo_2	20	27	PF02174	0.699
LIG_PTB_Phospho_1	20	26	PF10480	0.703
LIG_SH2_CRK	26	30	PF00017	0.692
LIG_SH2_NCK_1	26	30	PF00017	0.692
LIG_SH2_STAP1	515	519	PF00017	0.720
LIG_SH2_STAT5	26	29	PF00017	0.689
LIG_SH2_STAT5	493	496	PF00017	0.758
LIG_SH2_STAT5	515	518	PF00017	0.711
LIG_SUMO_SIM_par_1	68	75	PF11976	0.695
LIG_TYR_ITIM	24	29	PF00017	0.688
MOD_CK1_1	132	138	PF00069	0.740
MOD_CK1_1	192	198	PF00069	0.885
MOD_CK1_1	243	249	PF00069	0.890
MOD_CK1_1	255	261	PF00069	0.744
MOD_CK1_1	267	273	PF00069	0.744
MOD_CK1_1	310	316	PF00069	0.897
MOD_CK1_1	329	335	PF00069	0.661
MOD_CK1_1	341	347	PF00069	0.749
MOD_CK1_1	36	42	PF00069	0.690
MOD_CK1_1	384	390	PF00069	0.892
MOD_CK1_1	396	402	PF00069	0.747
MOD_CK1_1	408	414	PF00069	0.746
MOD_CK1_1	451	457	PF00069	0.891
MOD_CK1_1	474	480	PF00069	0.885
MOD_CK1_1	487	493	PF00069	0.654
MOD_CK2_1	162	168	PF00069	0.864
MOD_CK2_1	172	178	PF00069	0.756
MOD_CK2_1	182	188	PF00069	0.635
MOD_CK2_1	192	198	PF00069	0.635
MOD_CK2_1	202	208	PF00069	0.633
MOD_CK2_1	214	220	PF00069	0.730
MOD_CK2_1	226	232	PF00069	0.738
MOD_CK2_1	233	239	PF00069	0.649
MOD_CK2_1	245	251	PF00069	0.650
MOD_CK2_1	257	263	PF00069	0.744
MOD_CK2_1	269	275	PF00069	0.742
MOD_CK2_1	281	287	PF00069	0.743
MOD_CK2_1	293	299	PF00069	0.749
MOD_CK2_1	300	306	PF00069	0.653
MOD_CK2_1	312	318	PF00069	0.659
MOD_CK2_1	319	325	PF00069	0.647
MOD_CK2_1	331	337	PF00069	0.658
MOD_CK2_1	343	349	PF00069	0.748
MOD_CK2_1	355	361	PF00069	0.743
MOD_CK2_1	367	373	PF00069	0.748
MOD_CK2_1	374	380	PF00069	0.649
MOD_CK2_1	386	392	PF00069	0.653
MOD_CK2_1	398	404	PF00069	0.744
MOD_CK2_1	410	416	PF00069	0.744
MOD_CK2_1	422	428	PF00069	0.742
MOD_CK2_1	434	440	PF00069	0.745
MOD_CK2_1	441	447	PF00069	0.653
MOD_CK2_1	453	459	PF00069	0.653
MOD_CK2_1	465	471	PF00069	0.741
MOD_CK2_1	77	83	PF00069	0.712
MOD_GlcNHglycan	29	32	PF01048	0.491
MOD_GlcNHglycan	53	56	PF01048	0.497
MOD_GlcNHglycan	544	547	PF01048	0.549
MOD_GlcNHglycan	551	554	PF01048	0.427
MOD_GSK3_1	129	136	PF00069	0.719
MOD_GSK3_1	158	165	PF00069	0.831
MOD_GSK3_1	167	174	PF00069	0.762
MOD_GSK3_1	177	184	PF00069	0.648
MOD_GSK3_1	187	194	PF00069	0.632
MOD_GSK3_1	197	204	PF00069	0.633
MOD_GSK3_1	207	214	PF00069	0.632
MOD_GSK3_1	215	222	PF00069	0.654
MOD_GSK3_1	223	230	PF00069	0.686
MOD_GSK3_1	234	241	PF00069	0.646
MOD_GSK3_1	242	249	PF00069	0.652
MOD_GSK3_1	25	32	PF00069	0.443
MOD_GSK3_1	250	257	PF00069	0.687
MOD_GSK3_1	264	271	PF00069	0.714
MOD_GSK3_1	274	281	PF00069	0.759
MOD_GSK3_1	288	295	PF00069	0.716
MOD_GSK3_1	307	314	PF00069	0.653
MOD_GSK3_1	320	327	PF00069	0.722
MOD_GSK3_1	328	335	PF00069	0.798
MOD_GSK3_1	338	345	PF00069	0.668
MOD_GSK3_1	348	355	PF00069	0.640
MOD_GSK3_1	362	369	PF00069	0.717
MOD_GSK3_1	375	382	PF00069	0.724
MOD_GSK3_1	38	45	PF00069	0.528
MOD_GSK3_1	383	390	PF00069	0.792
MOD_GSK3_1	391	398	PF00069	0.689
MOD_GSK3_1	405	412	PF00069	0.716
MOD_GSK3_1	415	422	PF00069	0.761
MOD_GSK3_1	429	436	PF00069	0.715
MOD_GSK3_1	448	455	PF00069	0.649
MOD_GSK3_1	458	465	PF00069	0.762
MOD_GSK3_1	47	54	PF00069	0.574
MOD_GSK3_1	471	478	PF00069	0.722
MOD_GSK3_1	479	486	PF00069	0.772
MOD_GSK3_1	5	12	PF00069	0.728
MOD_GSK3_1	68	75	PF00069	0.695
MOD_GSK3_1	83	90	PF00069	0.539
MOD_N-GLC_1	502	507	PF02516	0.551
MOD_N-GLC_2	509	511	PF02516	0.522
MOD_NEK2_1	134	139	PF00069	0.748
MOD_NEK2_1	24	29	PF00069	0.688
MOD_NEK2_1	46	51	PF00069	0.680
MOD_NEK2_1	70	75	PF00069	0.695
MOD_NEK2_2	502	507	PF00069	0.751
MOD_PIKK_1	72	78	PF00454	0.704
MOD_PKA_2	483	489	PF00069	0.857
MOD_Plk_1	502	508	PF00069	0.742
MOD_Plk_1	83	89	PF00069	0.728
MOD_Plk_4	129	135	PF00069	0.717
MOD_ProDKin_1	153	159	PF00069	0.766
MOD_ProDKin_1	475	481	PF00069	0.884
MOD_ProDKin_1	485	491	PF00069	0.714
MOD_SUMO_for_1	1	4	PF00179	0.800
TRG_DiLeu_BaLyEn_6	17	22	PF01217	0.704
TRG_ENDOCYTIC_2	102	105	PF00928	0.712
TRG_ENDOCYTIC_2	26	29	PF00928	0.689
TRG_NES_CRM1_1	111	124	PF08389	0.714

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0R0HPY5	SOYBN	32%	57%
A7PW81	VITVI	30%	100%
B8ABC2	ORYSI	30%	100%
C0LGD7	ARATH	29%	58%
C0LGE0	ARATH	33%	55%
C0LGE4	ARATH	26%	63%
C0LGF4	ARATH	32%	94%
C0LGF5	ARATH	31%	52%
C0LGG7	ARATH	26%	58%
C0LGJ1	ARATH	28%	50%
C0LGK4	ARATH	35%	61%
C0LGK9	ARATH	28%	65%
C0LGN2	ARATH	27%	55%
C0LGP4	ARATH	31%	55%
C0LGP9	ARATH	26%	71%
C0LGQ5	ARATH	30%	45%
C0LGQ9	ARATH	34%	53%
C0LGR3	ARATH	30%	51%
C0LGS2	ARATH	35%	49%
C0LGS3	ARATH	30%	72%
C0LGT6	ARATH	31%	54%
C0LGU1	ARATH	29%	58%
C0LGV1	ARATH	34%	49%
C0LGW6	ARATH	28%	58%
C0LGX3	ARATH	29%	56%
F4HTV6	ARATH	33%	100%
F4I2N7	ARATH	23%	57%
F4J8G2	ARATH	28%	64%
F4J9A8	ARATH	33%	59%
F4JGB6	ARATH	33%	69%
F4K6B8	ARATH	30%	51%
G7JIK2	MEDTR	29%	57%
G9LZD7	ORYSJ	33%	48%
I1Z695	ORYSJ	30%	56%
O22476	ARATH	30%	46%
O22938	ARATH	28%	62%
O48788	ARATH	32%	84%
O48809	ARATH	28%	71%
O48849	ARATH	30%	62%
O48851	ARATH	33%	72%
O49318	ARATH	29%	49%
O49325	ARATH	28%	71%
O49545	ARATH	26%	55%
O49879	SOLLC	40%	66%
O65375	ARATH	29%	75%
O65440	ARATH	29%	56%
O80809	ARATH	27%	77%
O81765	ARATH	27%	80%
O82318	ARATH	30%	58%
P0DL10	MAIZE	31%	56%
P0DO05	SOLPI	40%	64%
P0DO06	SOLPI	40%	64%
P13813	PLAKN	35%	100%
P21978	LEIAM	40%	100%
P47179	YEAST	34%	48%
P47735	ARATH	33%	56%
P93194	IPONI	29%	50%
Q00874	ARATH	36%	100%
Q05091	PYRCO	32%	100%
Q0JA29	ORYSJ	31%	47%
Q0WR59	ARATH	34%	53%
Q0WVM4	ARATH	35%	88%
Q1MX30	ORYSI	29%	54%
Q1PEN0	ARATH	30%	77%
Q3E991	ARATH	31%	84%
Q40235	SOLPI	40%	64%
Q42371	ARATH	28%	57%
Q4PSE6	ARATH	27%	100%
Q5HY64	HUMAN	19%	54%
Q5MR23	SOLPI	40%	64%
Q5PP26	ARATH	28%	100%
Q5VQP7	ORYSJ	30%	100%
Q5Z9N5	ORYSJ	29%	56%
Q658G7	ORYSJ	30%	57%
Q67X31	ORYSJ	32%	90%
Q69JN6	ORYSJ	30%	46%
Q69SP5	ORYSJ	29%	57%
Q6JN46	SOLLC	26%	54%
Q6JN47	SOLLC	28%	54%
Q6K4T4	ORYSJ	33%	92%
Q6NQP4	ARATH	27%	100%
Q6R2K1	ARATH	25%	80%
Q6R2K2	ARATH	27%	81%
Q6XAT2	ARATH	31%	57%
Q7F8Q9	ORYSJ	31%	39%
Q7FZR1	ARATH	30%	69%
Q7G768	ORYSJ	26%	50%
Q8GRU6	LOTJA	30%	56%
Q8GT95	ORYSJ	32%	100%
Q8GUQ5	SOLLC	29%	46%
Q8GZ99	ARATH	29%	58%
Q8L899	SOLPE	29%	46%
Q8LPB4	DAUCA	29%	54%
Q8RX63	ARATH	28%	65%
Q8RZV7	ORYSJ	34%	43%
Q8VYT3	ARATH	35%	86%
Q8VZG8	ARATH	34%	53%
Q8W4S5	ARATH	38%	91%
Q940E8	MAIZE	28%	91%
Q942F3	ORYSJ	29%	50%
Q9ASQ6	ARATH	31%	55%
Q9C637	ARATH	32%	56%
Q9C699	ARATH	28%	57%
Q9C6A8	ARATH	30%	58%
Q9C7T7	ARATH	24%	57%
Q9C9H6	ARATH	29%	71%
Q9C9H7	ARATH	29%	66%
Q9FGL5	ARATH	30%	58%
Q9FII5	ARATH	29%	53%
Q9FIZ3	ARATH	29%	44%
Q9FK66	ARATH	29%	100%
Q9FL28	ARATH	33%	47%
Q9FL51	ARATH	29%	64%
Q9FP13	ORYSJ	30%	87%
Q9FPJ5	ARATH	28%	100%
Q9FRS6	ARATH	33%	54%
Q9FXF2	ARATH	35%	54%
Q9FZ59	ARATH	31%	51%
Q9LFG1	ARATH	26%	59%
Q9LH52	ARATH	29%	100%
Q9LHF1	ARATH	32%	100%
Q9LHP4	ARATH	33%	49%
Q9LJF3	ARATH	29%	48%
Q9LJM4	ARATH	27%	56%
Q9LJW7	ARATH	28%	78%
Q9LP24	ARATH	31%	50%
Q9LRT1	ARATH	29%	55%
Q9LS79	ARATH	26%	71%
Q9LS80	ARATH	24%	67%
Q9LT96	ARATH	31%	59%
Q9LVM0	ARATH	32%	85%
Q9LVP0	ARATH	28%	50%
Q9LY03	ARATH	31%	58%
Q9LYN8	ARATH	33%	47%
Q9LZV7	ARATH	30%	57%
Q9M0G7	ARATH	30%	55%
Q9M2Z1	ARATH	31%	55%
Q9M5J9	ARATH	29%	100%
Q9M6A7	SOYBN	32%	56%
Q9M8T0	ARATH	24%	89%
Q9M9X0	ARATH	29%	64%
Q9S7I6	ARATH	29%	48%
Q9S9U3	ARATH	31%	58%
Q9SCT4	ARATH	30%	67%
Q9SD62	ARATH	28%	54%
Q9SGP2	ARATH	28%	56%
Q9SH71	ARATH	29%	95%
Q9SHI2	ARATH	25%	50%
Q9SJH6	ARATH	26%	100%
Q9SKK2	ARATH	30%	57%
Q9SN38	ARATH	37%	100%
Q9SN46	ARATH	27%	65%
Q9SRL2	ARATH	31%	58%
Q9SRL7	ARATH	32%	59%
Q9SSD1	ARATH	30%	100%
Q9SSL9	ARATH	32%	50%
Q9SVM3	ARATH	29%	66%
Q9SYQ8	ARATH	28%	57%
Q9T0K5	ARATH	26%	73%
Q9XIB6	ARATH	25%	66%
Q9XIL9	ARATH	28%	76%
Q9ZPS9	ARATH	28%	49%
Q9ZU46	ARATH	32%	78%
Q9ZUI0	ARATH	28%	57%
Q9ZUK3	ARATH	30%	57%
Q9ZVR7	ARATH	31%	55%
Q9ZWC8	ARATH	32%	48%