Multidrug resistance protein, copy 1-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

multidrug resistance protein, copy 1-like protein

Species:

Leishmania braziliensis

UniProt:

A4HJB2_LEIBR

TriTrypDb:

LbrM.31.1520 , LBRM2903_310017900

Length:

225

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJB2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJB2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	92	96	PF00656	0.734
CLV_MEL_PAP_1	82	88	PF00089	0.758
CLV_NRD_NRD_1	126	128	PF00675	0.811
CLV_NRD_NRD_1	136	138	PF00675	0.642
CLV_NRD_NRD_1	141	143	PF00675	0.566
CLV_NRD_NRD_1	74	76	PF00675	0.804
CLV_PCSK_FUR_1	72	76	PF00082	0.798
CLV_PCSK_KEX2_1	125	127	PF00082	0.809
CLV_PCSK_KEX2_1	136	138	PF00082	0.624
CLV_PCSK_KEX2_1	141	143	PF00082	0.548
CLV_PCSK_KEX2_1	74	76	PF00082	0.804
CLV_PCSK_PC7_1	137	143	PF00082	0.820
CLV_PCSK_PC7_1	70	76	PF00082	0.790
DOC_ANK_TNKS_1	156	163	PF00023	0.817
DOC_CKS1_1	107	112	PF01111	0.793
DOC_WW_Pin1_4	106	111	PF00397	0.793
DOC_WW_Pin1_4	142	147	PF00397	0.817
LIG_14-3-3_CanoR_1	213	218	PF00244	0.815
LIG_FHA_1	174	180	PF00498	0.704
LIG_LIR_Gen_1	163	174	PF02991	0.792
LIG_LIR_Gen_1	185	194	PF02991	0.721
LIG_LIR_Nem_3	163	169	PF02991	0.799
LIG_LIR_Nem_3	185	190	PF02991	0.736
LIG_LIR_Nem_3	214	220	PF02991	0.810
LIG_LIR_Nem_3	54	58	PF02991	0.770
LIG_LIR_Nem_3	7	13	PF02991	0.660
LIG_PDZ_Class_1	220	225	PF00595	0.801
LIG_Pex14_2	23	27	PF04695	0.734
LIG_SH2_CRK	107	111	PF00017	0.791
LIG_SH2_CRK	203	207	PF00017	0.735
LIG_SH2_STAP1	11	15	PF00017	0.731
LIG_SH2_STAT3	11	14	PF00017	0.724
LIG_SH2_STAT5	203	206	PF00017	0.730
LIG_SH2_STAT5	28	31	PF00017	0.728
LIG_SH2_STAT5	81	84	PF00017	0.765
LIG_TRAF2_1	39	42	PF00917	0.771
LIG_TYR_ITIM	201	206	PF00017	0.726
LIG_TYR_ITIM	26	31	PF00017	0.731
MOD_CDK_SPK_2	106	111	PF00069	0.793
MOD_GlcNHglycan	16	21	PF01048	0.747
MOD_GlcNHglycan	183	187	PF01048	0.749
MOD_GlcNHglycan	41	46	PF01048	0.772
MOD_GlcNHglycan	64	67	PF01048	0.757
MOD_GSK3_1	216	223	PF00069	0.810
MOD_NEK2_1	190	195	PF00069	0.702
MOD_NEK2_1	220	225	PF00069	0.801
MOD_NEK2_1	26	31	PF00069	0.731
MOD_Plk_1	170	176	PF00069	0.785
MOD_Plk_4	170	176	PF00069	0.785
MOD_Plk_4	201	207	PF00069	0.730
MOD_Plk_4	26	32	PF00069	0.728
MOD_ProDKin_1	106	112	PF00069	0.794
MOD_ProDKin_1	142	148	PF00069	0.814
TRG_ENDOCYTIC_2	114	117	PF00928	0.800
TRG_ENDOCYTIC_2	203	206	PF00928	0.730
TRG_ENDOCYTIC_2	28	31	PF00928	0.728
TRG_ER_diArg_1	125	127	PF00400	0.809
TRG_ER_diArg_1	135	137	PF00400	0.650
TRG_ER_diArg_1	141	144	PF00400	0.551
TRG_ER_diArg_1	212	215	PF00400	0.811
TRG_ER_diArg_1	72	75	PF00400	0.797