Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved (fragment)

Species:

Leishmania braziliensis

UniProt:

A4HJ87_LEIBR

TriTrypDb:

LbrM.31.1270 , LBRM2903_310020700

Length:

428

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HJ87

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ87

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	134	136	PF00675	0.701
CLV_NRD_NRD_1	143	145	PF00675	0.580
CLV_NRD_NRD_1	164	166	PF00675	0.687
CLV_NRD_NRD_1	307	309	PF00675	0.593
CLV_NRD_NRD_1	50	52	PF00675	0.617
CLV_PCSK_FUR_1	140	144	PF00082	0.693
CLV_PCSK_KEX2_1	134	136	PF00082	0.701
CLV_PCSK_KEX2_1	142	144	PF00082	0.597
CLV_PCSK_KEX2_1	164	166	PF00082	0.687
CLV_PCSK_KEX2_1	193	195	PF00082	0.621
CLV_PCSK_KEX2_1	303	305	PF00082	0.574
CLV_PCSK_KEX2_1	307	309	PF00082	0.542
CLV_PCSK_KEX2_1	411	413	PF00082	0.645
CLV_PCSK_KEX2_1	50	52	PF00082	0.617
CLV_PCSK_PC1ET2_1	193	195	PF00082	0.621
CLV_PCSK_PC1ET2_1	303	305	PF00082	0.574
CLV_PCSK_PC1ET2_1	411	413	PF00082	0.645
CLV_PCSK_SKI1_1	12	16	PF00082	0.650
CLV_PCSK_SKI1_1	25	29	PF00082	0.322
CLV_PCSK_SKI1_1	254	258	PF00082	0.607
CLV_PCSK_SKI1_1	303	307	PF00082	0.571
CLV_PCSK_SKI1_1	349	353	PF00082	0.601
CLV_PCSK_SKI1_1	85	89	PF00082	0.663
DOC_CYCLIN_RxL_1	346	354	PF00134	0.790
DOC_CYCLIN_yCln2_LP_2	313	319	PF00134	0.779
DOC_MAPK_gen_1	164	175	PF00069	0.875
DOC_MAPK_gen_1	303	313	PF00069	0.766
DOC_MAPK_MEF2A_6	12	21	PF00069	0.449
DOC_MAPK_MEF2A_6	307	315	PF00069	0.765
DOC_MAPK_RevD_3	180	194	PF00069	0.850
DOC_MAPK_RevD_3	290	304	PF00069	0.773
DOC_PP2B_LxvP_1	313	316	PF13499	0.760
DOC_USP7_MATH_1	138	142	PF00917	0.887
DOC_USP7_MATH_1	160	164	PF00917	0.885
DOC_USP7_MATH_1	167	171	PF00917	0.782
DOC_USP7_MATH_1	275	279	PF00917	0.764
DOC_USP7_MATH_1	320	324	PF00917	0.817
DOC_USP7_MATH_1	376	380	PF00917	0.825
DOC_USP7_MATH_1	420	424	PF00917	0.832
DOC_USP7_MATH_1	53	57	PF00917	0.836
DOC_USP7_UBL2_3	193	197	PF12436	0.810
DOC_WW_Pin1_4	218	223	PF00397	0.831
DOC_WW_Pin1_4	232	237	PF00397	0.639
LIG_14-3-3_CanoR_1	134	138	PF00244	0.895
LIG_14-3-3_CanoR_1	142	150	PF00244	0.791
LIG_14-3-3_CanoR_1	267	276	PF00244	0.766
LIG_14-3-3_CanoR_1	32	39	PF00244	0.794
LIG_14-3-3_CanoR_1	341	350	PF00244	0.776
LIG_14-3-3_CanoR_1	375	381	PF00244	0.828
LIG_14-3-3_CanoR_1	387	395	PF00244	0.686
LIG_BIR_III_4	252	256	PF00653	0.817
LIG_BRCT_BRCA1_1	208	212	PF00533	0.815
LIG_EVH1_1	182	186	PF00568	0.854
LIG_FHA_1	312	318	PF00498	0.767
LIG_FHA_1	362	368	PF00498	0.820
LIG_FHA_1	414	420	PF00498	0.837
LIG_FHA_2	149	155	PF00498	0.883
LIG_Integrin_RGD_1	308	310	PF01839	0.581
LIG_LIR_Gen_1	10	21	PF02991	0.449
LIG_LIR_Gen_1	354	360	PF02991	0.802
LIG_LIR_Nem_3	10	16	PF02991	0.449
LIG_LIR_Nem_3	354	358	PF02991	0.798
LIG_NRBOX	347	353	PF00104	0.793
LIG_Pex14_2	118	122	PF04695	0.864
LIG_SH2_CRK	23	27	PF00017	0.549
LIG_SH2_CRK	355	359	PF00017	0.802
LIG_SH2_NCK_1	342	346	PF00017	0.767
LIG_SH2_STAP1	301	305	PF00017	0.761
LIG_SH2_STAP1	342	346	PF00017	0.767
LIG_SH2_STAT5	23	26	PF00017	0.549
LIG_SH3_2	183	188	PF14604	0.857
LIG_SH3_3	172	178	PF00018	0.871
LIG_SH3_3	180	186	PF00018	0.754
LIG_SH3_3	198	204	PF00018	0.578
LIG_SH3_3	221	227	PF00018	0.837
LIG_SH3_3	258	264	PF00018	0.783
LIG_SH3_3	3	9	PF00018	0.615
LIG_SUMO_SIM_par_1	363	371	PF11976	0.825
LIG_TYR_ITIM	21	26	PF00017	0.549
LIG_TYR_ITIM	353	358	PF00017	0.799
LIG_UBA3_1	17	25	PF00899	0.549
MOD_CDK_SPK_2	218	223	PF00069	0.831
MOD_CDK_SPxxK_3	218	225	PF00069	0.834
MOD_CK1_1	145	151	PF00069	0.888
MOD_CK1_1	199	205	PF00069	0.801
MOD_CK1_1	231	237	PF00069	0.815
MOD_CK1_1	247	253	PF00069	0.597
MOD_CK1_1	340	346	PF00069	0.772
MOD_CK1_1	56	62	PF00069	0.863
MOD_CK1_1	81	87	PF00069	0.866
MOD_CK1_1	96	102	PF00069	0.679
MOD_CK2_1	148	154	PF00069	0.883
MOD_CK2_1	420	426	PF00069	0.832
MOD_GlcNHglycan	156	159	PF01048	0.684
MOD_GlcNHglycan	277	280	PF01048	0.557
MOD_GlcNHglycan	372	375	PF01048	0.632
MOD_GlcNHglycan	389	392	PF01048	0.423
MOD_GlcNHglycan	90	93	PF01048	0.661
MOD_GlcNHglycan	95	98	PF01048	0.599
MOD_GSK3_1	138	145	PF00069	0.889
MOD_GSK3_1	202	209	PF00069	0.793
MOD_GSK3_1	228	235	PF00069	0.829
MOD_GSK3_1	320	327	PF00069	0.815
MOD_GSK3_1	333	340	PF00069	0.612
MOD_GSK3_1	64	71	PF00069	0.874
MOD_GSK3_1	77	84	PF00069	0.702
MOD_N-GLC_1	218	223	PF02516	0.631
MOD_N-GLC_1	259	264	PF02516	0.582
MOD_N-GLC_1	88	93	PF02516	0.659
MOD_NEK2_1	228	233	PF00069	0.836
MOD_NEK2_1	269	274	PF00069	0.762
MOD_NEK2_1	292	297	PF00069	0.791
MOD_NEK2_1	351	356	PF00069	0.803
MOD_NEK2_1	368	373	PF00069	0.620
MOD_NEK2_1	39	44	PF00069	0.788
MOD_NEK2_1	401	406	PF00069	0.857
MOD_NEK2_1	413	418	PF00069	0.689
MOD_PIKK_1	133	139	PF00454	0.894
MOD_PIKK_1	202	208	PF00454	0.791
MOD_PIKK_1	32	38	PF00454	0.794
MOD_PIKK_1	53	59	PF00454	0.844
MOD_PKA_1	142	148	PF00069	0.892
MOD_PKA_2	133	139	PF00069	0.894
MOD_PKA_2	142	148	PF00069	0.780
MOD_PKA_2	154	160	PF00069	0.734
MOD_PKA_2	167	173	PF00069	0.710
MOD_PKA_2	206	212	PF00069	0.809
MOD_PKA_2	340	346	PF00069	0.772
MOD_PKB_1	140	148	PF00069	0.891
MOD_Plk_1	244	250	PF00069	0.790
MOD_Plk_4	244	250	PF00069	0.790
MOD_Plk_4	269	275	PF00069	0.762
MOD_ProDKin_1	218	224	PF00069	0.831
MOD_ProDKin_1	232	238	PF00069	0.635
TRG_DiLeu_BaEn_1	285	290	PF01217	0.760
TRG_ENDOCYTIC_2	23	26	PF00928	0.549
TRG_ENDOCYTIC_2	355	358	PF00928	0.800
TRG_ER_diArg_1	140	143	PF00400	0.891
TRG_ER_diArg_1	306	308	PF00400	0.778
TRG_ER_diArg_1	386	389	PF00400	0.844
TRG_ER_diArg_1	49	51	PF00400	0.813
TRG_Pf-PMV_PEXEL_1	188	192	PF00026	0.649
TRG_Pf-PMV_PEXEL_1	50	54	PF00026	0.618