Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJ85_LEIBR

TriTrypDb:

LbrM.31.1250 , LBRM2903_310020600

Length:

326

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJ85

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ85

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	304	308	PF00656	0.645
CLV_NRD_NRD_1	151	153	PF00675	0.820
CLV_NRD_NRD_1	213	215	PF00675	0.677
CLV_NRD_NRD_1	236	238	PF00675	0.534
CLV_NRD_NRD_1	242	244	PF00675	0.518
CLV_PCSK_KEX2_1	150	152	PF00082	0.807
CLV_PCSK_SKI1_1	215	219	PF00082	0.539
DOC_MAPK_gen_1	169	178	PF00069	0.585
DOC_MAPK_MEF2A_6	171	180	PF00069	0.529
DOC_PP1_RVXF_1	23	30	PF00149	0.500
DOC_PP1_RVXF_1	3	10	PF00149	0.513
DOC_PP4_MxPP_1	311	314	PF00568	0.532
DOC_USP7_MATH_1	107	111	PF00917	0.632
DOC_USP7_MATH_1	136	140	PF00917	0.554
DOC_USP7_MATH_1	226	230	PF00917	0.647
DOC_USP7_MATH_1	314	318	PF00917	0.529
DOC_USP7_MATH_1	64	68	PF00917	0.615
DOC_USP7_UBL2_3	244	248	PF12436	0.570
DOC_WW_Pin1_4	103	108	PF00397	0.626
DOC_WW_Pin1_4	116	121	PF00397	0.503
LIG_14-3-3_CanoR_1	17	24	PF00244	0.480
LIG_14-3-3_CanoR_1	243	249	PF00244	0.671
LIG_14-3-3_CanoR_1	61	71	PF00244	0.545
LIG_14-3-3_CanoR_1	93	100	PF00244	0.568
LIG_FHA_1	200	206	PF00498	0.535
LIG_FHA_1	95	101	PF00498	0.675
LIG_FHA_2	304	310	PF00498	0.547
LIG_LIR_Apic_2	297	303	PF02991	0.541
LIG_LIR_Gen_1	14	22	PF02991	0.489
LIG_LIR_Nem_3	14	18	PF02991	0.636
LIG_LIR_Nem_3	266	271	PF02991	0.557
LIG_LYPXL_yS_3	268	271	PF13949	0.549
LIG_SH2_CRK	15	19	PF00017	0.497
LIG_SH2_STAT5	28	31	PF00017	0.486
LIG_SH3_3	52	58	PF00018	0.671
LIG_TRAF2_1	313	316	PF00917	0.530
LIG_TYR_ITSM	264	271	PF00017	0.551
MOD_CK1_1	20	26	PF00069	0.618
MOD_CK1_1	229	235	PF00069	0.539
MOD_CK1_1	250	256	PF00069	0.545
MOD_CK1_1	43	49	PF00069	0.496
MOD_CK1_1	95	101	PF00069	0.567
MOD_CK2_1	291	297	PF00069	0.610
MOD_CK2_1	303	309	PF00069	0.546
MOD_CK2_1	69	75	PF00069	0.647
MOD_Cter_Amidation	148	151	PF01082	0.583
MOD_GlcNHglycan	103	106	PF01048	0.560
MOD_GlcNHglycan	147	150	PF01048	0.719
MOD_GlcNHglycan	153	156	PF01048	0.727
MOD_GlcNHglycan	230	234	PF01048	0.678
MOD_GlcNHglycan	244	247	PF01048	0.530
MOD_GlcNHglycan	292	296	PF01048	0.579
MOD_GlcNHglycan	30	33	PF01048	0.667
MOD_GlcNHglycan	42	45	PF01048	0.493
MOD_GlcNHglycan	66	69	PF01048	0.694
MOD_GlcNHglycan	71	74	PF01048	0.623
MOD_GSK3_1	103	110	PF00069	0.632
MOD_GSK3_1	132	139	PF00069	0.562
MOD_GSK3_1	16	23	PF00069	0.556
MOD_GSK3_1	199	206	PF00069	0.559
MOD_GSK3_1	28	35	PF00069	0.549
MOD_LATS_1	289	295	PF00433	0.538
MOD_N-GLC_1	101	106	PF02516	0.558
MOD_N-GLC_1	136	141	PF02516	0.606
MOD_N-GLC_1	178	183	PF02516	0.515
MOD_NEK2_1	16	21	PF00069	0.527
MOD_NEK2_1	203	208	PF00069	0.684
MOD_NEK2_1	40	45	PF00069	0.509
MOD_NEK2_2	3	8	PF00069	0.511
MOD_PIKK_1	62	68	PF00454	0.547
MOD_PIKK_1	92	98	PF00454	0.568
MOD_PKA_1	145	151	PF00069	0.542
MOD_PKA_1	215	221	PF00069	0.631
MOD_PKA_1	237	243	PF00069	0.529
MOD_PKA_2	151	157	PF00069	0.652
MOD_PKA_2	16	22	PF00069	0.601
MOD_PKA_2	242	248	PF00069	0.671
MOD_PKA_2	69	75	PF00069	0.625
MOD_PKA_2	92	98	PF00069	0.578
MOD_Plk_1	74	80	PF00069	0.520
MOD_Plk_4	11	17	PF00069	0.505
MOD_Plk_4	51	57	PF00069	0.651
MOD_ProDKin_1	103	109	PF00069	0.624
MOD_ProDKin_1	116	122	PF00069	0.502
MOD_SUMO_for_1	227	230	PF00179	0.533
MOD_SUMO_for_1	256	259	PF00179	0.548
TRG_ENDOCYTIC_2	15	18	PF00928	0.500
TRG_ENDOCYTIC_2	268	271	PF00928	0.549
TRG_ER_diArg_1	150	152	PF00400	0.784

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IJY9	Leishmania donovani	35%	100%
A4I6M9	Leishmania infantum	36%	100%
E9B1Q2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%